2YA3A

Structure of the regulatory fragment of mammalian ampk in complex with coumarin adp
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
156
structure length
102
Chain Sequence
MAWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDEVAPRPGSHTIEFFEMCANLIKNSCTV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of Mammalian Ampk and its Regulation by Adp
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1
total genus 21
structure length 102
sequence length 156
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2011-02-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2ya3A01
1V5SA 2Y8LA 2V9JA 3TDHA 2EHBD 2QRCA 2ZFDB 3T4NA 2QREA 4EAJA 1UL7A 4EAKA 2QLVA 2V8QA 4EAIA 4EALA 2OOYA 2OOXA 2YA3A 2QRDA 4CFFA 4EAGA 3OSEA 2V92A 3TE5A 2Y8QA 2QR1A
chains in the Genus database with same CATH superfamily
1V5SA 3CW7A 3D4VA 1KYDA 1C4GA 1W80A 2EHBD 5AN4A 1PVSA 3BKQX 2MZ8A 2FGTA 2FKFA 3VN5A 1QN8A 4PY5A 3I0WA 2D0CA 1WJWA 3EIKA 4QG5A 1QN4A 2O3OA 3RSMA 1VOLB 3UW2A 3ULXA 2H5AX 3OCIA 1JFIC 2FKMX 2YA3A 1C9BB 1QN3A 1TUOA 4DULA 1QN7A 1QNCA 1VTOA 2YH5A 1QNEA 3OH6A 1MP9A 3EAYA 1UT7A 3ASMA 4WXAA 1P5DX 4EAGA 1DIZA 3DPTA 3TE5A 5IYCP 1PCJX 2Z8UA 3F10A 2DKAA 3C04A 3OGDA 1M3HA 3IH7A 2NOHA 2Y8LA 1QTPA 1N39A 1EBMA 3CWSA 2G30A 3H1ZA 1KY6A 2DKCA 2QREA 2FUVA 1LWVA 2NLVA 1M3QA 1NVPA 2JHJA 1YTFA 1Q9UA 2V8QA 3SNSA 2HL8A 4EAIA 4B0AA 1NGMA 2NOEA 2OOYA 1CDWA 1T6AA 1P5GX 2NVMA 4I8OA 2VJ0A 1B9KA 2JPIA 2NWVA 3D7QA 5HSHA 2QRDA 4CFFA 3CVSA 3CWAA 3I0XA 1M5Q1 1N3CA 1KYUA 1C47A 3OSEA 1D3UA 3F0ZA 3PMGA 3I3WA 1PZDA 1PCMX 2NOZA 4D7RA 1KYFA 1AISA 3TDHA 4D7QA 5F9CA 4BJUA 5EPCA 2JHNA 2QRCA 3KRMA 5IYBP 1QN9A 3T4NA 1QNBA 4RODB 1EUVA 4EJYA 1UL7A 3OH9A 1MPGA 3OC3C 5JMVD 4HJHA 3CWTA 1QTSA 1VOKA 2Z0FA 2IV8A 1PCZA 2HL9A 1VTLE 2NOFA 4WZSD 5BMPA 2XHIA 3KTUA 1KFIA 4MRQA 1FN7A 1LWYA 1K2YX 1QNAA 1LXTA 2V92A 3PDKA 1J3MA 3NA5A 4EJZA 2QR1A 1KY7A 2R5XA 1TGHA 2I5WA 4IL8A 1N3AA 1TBPA 1YQMA 2V9JA 4C7PA 1KFQA 4TPSA 2ZFDB 2NOIA 2NOLA 3DPUA 1YQKA 3CWUA 2LAEA 3ENCA 2D0AA 4EAJA 4EAKA 5BMNA 1NH2A 1YTBA 2HZSA 2QLVA 5KL0A 2HZMA 1R4XA 1RM1A 2DKDA 2D0BA 3N89A 3ENOC 4WX8A 1UT4A 2JOIA 1TBAB 2OOXA 4EALA 1HU0A 4ROCB 1JDYA 4Q11A 1XSZA 2PWWA 2HKPA 1QN6A 3CVTA 2H4LX 1E42A 1K35A 5JN5A 1WQAA 3HS9A 1LWWA 2NOBA 1VKLA 3OLPA 1QN5A 1KO9A 3RPJA 3HS8A 1YQRA 5IYDP 3OSTA 1YQLA 2Y8QA 2MJ7A 4ROEB 2F7LA 2IV9A 3OSMA
chains in the Genus database with same CATH topology
1V5SA 2Y8LA 2V9JA 3TDHA 2EHBD 2QRCA 2ZFDB 3T4NA 2QREA 4EAJA 1UL7A 4EAKA 2QLVA 2V8QA 4EAIA 4EALA 2OOYA 2OOXA 2YA3A 2QRDA 4CFFA 4EAGA 3OSEA 2V92A 3TE5A 2Y8QA 2QR1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1V5S A;  2Y8L A;  2V9J A;  3TDH A;  2EHB D;  2QRC A;  2ZFD B;  3T4N A;  2QRE A;  4EAJ A;  1UL7 A;  4EAK A;  2QLV A;  2V8Q A;  4EAI A;  4EAL A;  2OOY A;  2OOX A;  2YA3 A;  2QRD A;  4CFF A;  4EAG A;  3OSE A;  2V92 A;  3TE5 A;  2Y8Q A;  2QR1 A; 
#chains in the Genus database with same CATH topology
 1V5S A;  3CW7 A;  3D4V A;  1KYD A;  1C4G A;  1W80 A;  2EHB D;  5AN4 A;  1PVS A;  3BKQ X;  2MZ8 A;  2FGT A;  2FKF A;  3VN5 A;  1QN8 A;  4PY5 A;  3I0W A;  2D0C A;  1WJW A;  3EIK A;  4QG5 A;  1QN4 A;  2O3O A;  3RSM A;  1VOL B;  3UW2 A;  3ULX A;  2H5A X;  3OCI A;  1JFI C;  2FKM X;  2YA3 A;  1C9B B;  1QN3 A;  1TUO A;  4DUL A;  1QN7 A;  1QNC A;  1VTO A;  2YH5 A;  1QNE A;  3OH6 A;  1MP9 A;  3EAY A;  1UT7 A;  3ASM A;  4WXA A;  1P5D X;  4EAG A;  1DIZ A;  3DPT A;  3TE5 A;  5IYC P;  1PCJ X;  2Z8U A;  3F10 A;  2DKA A;  3C04 A;  3OGD A;  1M3H A;  3IH7 A;  2NOH A;  2Y8L A;  1QTP A;  1N39 A;  1EBM A;  3CWS A;  2G30 A;  3H1Z A;  1KY6 A;  2DKC A;  2QRE A;  2FUV A;  1LWV A;  2NLV A;  1M3Q A;  1NVP A;  2JHJ A;  1YTF A;  1Q9U A;  2V8Q A;  3SNS A;  2HL8 A;  4EAI A;  4B0A A;  1NGM A;  2NOE A;  2OOY A;  1CDW A;  1T6A A;  1P5G X;  2NVM A;  4I8O A;  2VJ0 A;  1B9K A;  2JPI A;  2NWV A;  3D7Q A;  5HSH A;  2QRD A;  4CFF A;  3CVS A;  3CWA A;  3I0X A;  1M5Q 1;  1N3C A;  1KYU A;  1C47 A;  3OSE A;  1D3U A;  3F0Z A;  3PMG A;  3I3W A;  1PZD A;  1PCM X;  2NOZ A;  4D7R A;  1KYF A;  1AIS A;  3TDH A;  4D7Q A;  5F9C A;  4BJU A;  5EPC A;  2JHN A;  2QRC A;  3KRM A;  5IYB P;  1QN9 A;  3T4N A;  1QNB A;  4ROD B;  1EUV A;  4EJY A;  1UL7 A;  3OH9 A;  1MPG A;  3OC3 C;  5JMV D;  4HJH A;  3CWT A;  1QTS A;  1VOK A;  2Z0F A;  2IV8 A;  1PCZ A;  2HL9 A;  1VTL E;  2NOF A;  4WZS D;  5BMP A;  2XHI A;  3KTU A;  1KFI A;  4MRQ A;  1FN7 A;  1LWY A;  1K2Y X;  1QNA A;  1LXT A;  2V92 A;  3PDK A;  1J3M A;  3NA5 A;  4EJZ A;  2QR1 A;  1KY7 A;  2R5X A;  1TGH A;  2I5W A;  4IL8 A;  1N3A A;  1TBP A;  1YQM A;  2V9J A;  4C7P A;  1KFQ A;  4TPS A;  2ZFD B;  2NOI A;  2NOL A;  3DPU A;  1YQK A;  3CWU A;  2LAE A;  3ENC A;  2D0A A;  4EAJ A;  4EAK A;  5BMN A;  1NH2 A;  1YTB A;  2HZS A;  2QLV A;  5KL0 A;  2HZM A;  1R4X A;  1RM1 A;  2DKD A;  2D0B A;  3N89 A;  3ENO C;  4WX8 A;  1UT4 A;  2JOI A;  1TBA B;  2OOX A;  4EAL A;  1HU0 A;  4ROC B;  1JDY A;  4Q11 A;  1XSZ A;  2PWW A;  2HKP A;  1QN6 A;  3CVT A;  2H4L X;  1E42 A;  1K35 A;  5JN5 A;  1WQA A;  3HS9 A;  1LWW A;  2NOB A;  1VKL A;  3OLP A;  1QN5 A;  1KO9 A;  3RPJ A;  3HS8 A;  1YQR A;  5IYD P;  3OST A;  1YQL A;  2Y8Q A;  2MJ7 A;  4ROE B;  2F7L A;  2IV9 A;  3OSM A; 
#chains in the Genus database with same CATH homology
 1V5S A;  2Y8L A;  2V9J A;  3TDH A;  2EHB D;  2QRC A;  2ZFD B;  3T4N A;  2QRE A;  4EAJ A;  1UL7 A;  4EAK A;  2QLV A;  2V8Q A;  4EAI A;  4EAL A;  2OOY A;  2OOX A;  2YA3 A;  2QRD A;  4CFF A;  4EAG A;  3OSE A;  2V92 A;  3TE5 A;  2Y8Q A;  2QR1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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