1NVPA

Human tfiia/tbp/dna complex
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
180
structure length
180
Chain Sequence
SGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel interactions between the components of human and yeast TFIIA/TBP/DNA complexes.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords 5'-D(*GP*GP*GP*GP*GP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*G)-3'
total genus 45
structure length 180
sequence length 180
ec nomenclature
pdb deposition date 2003-02-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00352 TBP Transcription factor TFIID (or TATA-binding protein, TBP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 1nvpA01
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 1nvpA02
3H1ZA 1PCZA 3EIKA 1QTPA 1VTLE 1AISA 1KY6A 1QNBA 1TBAB 1VTOA 1TBPA 2MJ7A 3ASMA 1YTBA 1KY7A 1JFIC 1KYDA 1D3UA 2D0AA 4RODB 1CDWA 1QNCA 3HS9A 1W80A 3OC3C 1NVPA 1R4XA 1RM1A 3OCIA 1QN6A 1QTSA 4B0AA 1QN3A 2D0CA 1KYFA 2D0BA 2G30A 4ROCB 3HS8A 4ROEB 1C9BB 1QN5A 4PY5A 4WZSD 1NGMA 1NH2A 2Z8UA 1QN8A 1E42A 5IYBP 2VJ0A 1QN9A 1PZDA 1B9KA 5IYDP 1QNAA 1QN7A 1VOKA 5IYCP 1VOLB 1QN4A 1MP9A 1QNEA 3VN5A 1KYUA 1YTFA 2IV9A 1TGHA 2IV8A
chains in the Genus database with same CATH superfamily
2DKAA 1PCZA 3ENCA 2NOIA 3CVSA 1EUVA 2NVMA 2Y8QA 1VTOA 2NOHA 3KTUA 3I0WA 2JOIA 1T6AA 2D0AA 2NWVA 3CWTA 1Q9UA 1QNCA 5KL0A 4D7QA 1W80A 2HKPA 2FUVA 3OCIA 1QN6A 1QTSA 2V9JA 2O3OA 2QLVA 1UT7A 4I8OA 3CWAA 2QRDA 3I0XA 4WZSD 3UW2A 3F10A 1NH2A 3BKQX 1E42A 2VJ0A 1N3CA 1DIZA 1PZDA 1B9KA 1MPGA 2JHJA 2NLVA 2OOYA 1HU0A 4TPSA 2HL9A 1QN4A 1K2YX 5AN4A 5JN5A 1QNEA 2YH5A 1LWWA 4EJYA 3D4VA 3DPUA 4EALA 1TGHA 2PWWA 2LAEA 3H1ZA 2MZ8A 4CFFA 2NOFA 1TBPA 1EBMA 1KFQA 1C4GA 3D7QA 3N89A 1YTBA 3CVTA 3ULXA 2XHIA 2NOEA 1JFIC 1KYDA 1UT4A 4HJHA 1WJWA 4RODB 1CDWA 1KFIA 3HS9A 2YA3A 2H4LX 4QG5A 1YQKA 1NVPA 1RM1A 1LWYA 4Q11A 4B0AA 1QN3A 2D0CA 4ROEB 3OGDA 2NOBA 4WXAA 3OH9A 3OLPA 4C7PA 1QN9A 4MRQA 1VOLB 1MP9A 2HL8A 1PVSA 1YQRA 1KYUA 1UL7A 5HSHA 3OH6A 2IV8A 3TDHA 1FN7A 3OSTA 1QN7A 2NOZA 1XSZA 1AISA 5F9CA 1QNBA 2MJ7A 2V8QA 2HZMA 3PMGA 1VKLA 3ASMA 3OSMA 1M3HA 3ENOC 1V5SA 1C47A 5JMVD 2FKMX 1N39A 5BMPA 2FGTA 1R4XA 3SNSA 2JPIA 1YQMA 4EAIA 5EPCA 1TUOA 3IH7A 4ROCB 3HS8A 1QN5A 2Z8UA 2ZFDB 5IYDP 1P5GX 1QNAA 2DKDA 1PCJX 1VOKA 3CWSA 3RPJA 4D7RA 2V92A 1M3QA 1P5DX 3I3WA 3CWUA 2R5XA 3DPTA 4EAGA 2OOXA 3EIKA 1QTPA 4DULA 1VTLE 1KY6A 1TBAB 1J3MA 2DKCA 2QREA 4WX8A 3PDKA 1KY7A 1PCMX 3CW7A 1D3UA 1JDYA 2QRCA 2Z0FA 5BMNA 1WQAA 3NA5A 3KRMA 3OC3C 2F7LA 2EHBD 2Y8LA 4IL8A 1KYFA 1K35A 2D0BA 4EJZA 2G30A 4EAKA 1C9BB 2I5WA 2HZSA 2QR1A 4EAJA 1KO9A 4PY5A 3F0ZA 1M5Q1 1NGMA 1QN8A 1LWVA 5IYBP 1YQLA 3OSEA 2FKFA 3C04A 1LXTA 2H5AX 3TE5A 2NOLA 3RSMA 5IYCP 3T4NA 1N3AA 3VN5A 1YTFA 2IV9A 4BJUA 2JHNA 3EAYA
chains in the Genus database with same CATH topology
2NOIA 1PCZA 2NOHA 1VTOA 3KTUA 3I0WA 2JOIA 2D0AA 1QNCA 1W80A 3OCIA 1QN6A 1QTSA 2O3OA 1UT7A 4I8OA 3I0XA 4WZSD 3F10A 1NH2A 1E42A 2VJ0A 1N3CA 1PZDA 1B9KA 1HU0A 4TPSA 1QN4A 5AN4A 1QNEA 2YH5A 1LWWA 4EJYA 1TGHA 3DPUA 2LAEA 3H1ZA 2MZ8A 2NOFA 1TBPA 1EBMA 1YTBA 3N89A 3ULXA 2XHIA 2NOEA 1JFIC 1KYDA 1UT4A 1CDWA 4RODB 3HS9A 1YQKA 1NVPA 1LWYA 1RM1A 4Q11A 4B0AA 1QN3A 2D0CA 4ROEB 2NOBA 1QN9A 1VOLB 1MP9A 1YQRA 1KYUA 2IV8A 1FN7A 3OSTA 1QN7A 2NOZA 1AISA 1QNBA 2MJ7A 2HZMA 3ASMA 3OSMA 1M3HA 1N39A 2FGTA 1R4XA 3SNSA 1YQMA 3IH7A 4ROCB 3HS8A 1QN5A 2Z8UA 5IYDP 1QNAA 1VOKA 3RPJA 1M3QA 3DPTA 3EIKA 1QTPA 4DULA 1VTLE 1KY6A 1TBAB 1KY7A 1D3UA 3KRMA 3OC3C 1KYFA 2D0BA 4EJZA 2G30A 1C9BB 2I5WA 2HZSA 1KO9A 4PY5A 3F0ZA 1NGMA 1QN8A 1LWVA 5IYBP 1YQLA 2NOLA 1N3AA 5IYCP 3VN5A 1YTFA 2IV9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H1Z A;  1PCZ A;  3EIK A;  1QTP A;  1VTL E;  1AIS A;  1KY6 A;  1QNB A;  1TBA B;  1VTO A;  1TBP A;  2MJ7 A;  3ASM A;  1YTB A;  1KY7 A;  1JFI C;  1KYD A;  1D3U A;  2D0A A;  4ROD B;  1CDW A;  1QNC A;  3HS9 A;  1W80 A;  3OC3 C;  1NVP A;  1R4X A;  1RM1 A;  3OCI A;  1QN6 A;  1QTS A;  4B0A A;  1QN3 A;  2D0C A;  1KYF A;  2D0B A;  2G30 A;  4ROC B;  3HS8 A;  4ROE B;  1C9B B;  1QN5 A;  4PY5 A;  4WZS D;  1NGM A;  1NH2 A;  2Z8U A;  1QN8 A;  1E42 A;  5IYB P;  2VJ0 A;  1QN9 A;  1PZD A;  1B9K A;  5IYD P;  1QNA A;  1QN7 A;  1VOK A;  5IYC P;  1VOL B;  1QN4 A;  1MP9 A;  1QNE A;  3VN5 A;  1KYU A;  1YTF A;  2IV9 A;  1TGH A;  2IV8 A; 
#chains in the Genus database with same CATH topology
 2DKA A;  1PCZ A;  3ENC A;  2NOI A;  3CVS A;  1EUV A;  2NVM A;  2Y8Q A;  1VTO A;  2NOH A;  3KTU A;  3I0W A;  2JOI A;  1T6A A;  2D0A A;  2NWV A;  3CWT A;  1Q9U A;  1QNC A;  5KL0 A;  4D7Q A;  1W80 A;  2HKP A;  2FUV A;  3OCI A;  1QN6 A;  1QTS A;  2V9J A;  2O3O A;  2QLV A;  1UT7 A;  4I8O A;  3CWA A;  2QRD A;  3I0X A;  4WZS D;  3UW2 A;  3F10 A;  1NH2 A;  3BKQ X;  1E42 A;  2VJ0 A;  1N3C A;  1DIZ A;  1PZD A;  1B9K A;  1MPG A;  2JHJ A;  2NLV A;  2OOY A;  1HU0 A;  4TPS A;  2HL9 A;  1QN4 A;  1K2Y X;  5AN4 A;  5JN5 A;  1QNE A;  2YH5 A;  1LWW A;  4EJY A;  3D4V A;  3DPU A;  4EAL A;  1TGH A;  2PWW A;  2LAE A;  3H1Z A;  2MZ8 A;  4CFF A;  2NOF A;  1TBP A;  1EBM A;  1KFQ A;  1C4G A;  3D7Q A;  3N89 A;  1YTB A;  3CVT A;  3ULX A;  2XHI A;  2NOE A;  1JFI C;  1KYD A;  1UT4 A;  4HJH A;  1WJW A;  4ROD B;  1CDW A;  1KFI A;  3HS9 A;  2YA3 A;  2H4L X;  4QG5 A;  1YQK A;  1NVP A;  1RM1 A;  1LWY A;  4Q11 A;  4B0A A;  1QN3 A;  2D0C A;  4ROE B;  3OGD A;  2NOB A;  4WXA A;  3OH9 A;  3OLP A;  4C7P A;  1QN9 A;  4MRQ A;  1VOL B;  1MP9 A;  2HL8 A;  1PVS A;  1YQR A;  1KYU A;  1UL7 A;  5HSH A;  3OH6 A;  2IV8 A;  3TDH A;  1FN7 A;  3OST A;  1QN7 A;  2NOZ A;  1XSZ A;  1AIS A;  5F9C A;  1QNB A;  2MJ7 A;  2V8Q A;  2HZM A;  3PMG A;  1VKL A;  3ASM A;  3OSM A;  1M3H A;  3ENO C;  1V5S A;  1C47 A;  5JMV D;  2FKM X;  1N39 A;  5BMP A;  2FGT A;  1R4X A;  3SNS A;  2JPI A;  1YQM A;  4EAI A;  5EPC A;  1TUO A;  3IH7 A;  4ROC B;  3HS8 A;  1QN5 A;  2Z8U A;  2ZFD B;  5IYD P;  1P5G X;  1QNA A;  2DKD A;  1PCJ X;  1VOK A;  3CWS A;  3RPJ A;  4D7R A;  2V92 A;  1M3Q A;  1P5D X;  3I3W A;  3CWU A;  2R5X A;  3DPT A;  4EAG A;  2OOX A;  3EIK A;  1QTP A;  4DUL A;  1VTL E;  1KY6 A;  1TBA B;  1J3M A;  2DKC A;  2QRE A;  4WX8 A;  3PDK A;  1KY7 A;  1PCM X;  3CW7 A;  1D3U A;  1JDY A;  2QRC A;  2Z0F A;  5BMN A;  1WQA A;  3NA5 A;  3KRM A;  3OC3 C;  2F7L A;  2EHB D;  2Y8L A;  4IL8 A;  1KYF A;  1K35 A;  2D0B A;  4EJZ A;  2G30 A;  4EAK A;  1C9B B;  2I5W A;  2HZS A;  2QR1 A;  4EAJ A;  1KO9 A;  4PY5 A;  3F0Z A;  1M5Q 1;  1NGM A;  1QN8 A;  1LWV A;  5IYB P;  1YQL A;  3OSE A;  2FKF A;  3C04 A;  1LXT A;  2H5A X;  3TE5 A;  2NOL A;  3RSM A;  5IYC P;  3T4N A;  1N3A A;  3VN5 A;  1YTF A;  2IV9 A;  4BJU A;  2JHN A;  3EAY A; 
#chains in the Genus database with same CATH homology
 2NOI A;  1PCZ A;  2NOH A;  1VTO A;  3KTU A;  3I0W A;  2JOI A;  2D0A A;  1QNC A;  1W80 A;  3OCI A;  1QN6 A;  1QTS A;  2O3O A;  1UT7 A;  4I8O A;  3I0X A;  4WZS D;  3F10 A;  1NH2 A;  1E42 A;  2VJ0 A;  1N3C A;  1PZD A;  1B9K A;  1HU0 A;  4TPS A;  1QN4 A;  5AN4 A;  1QNE A;  2YH5 A;  1LWW A;  4EJY A;  1TGH A;  3DPU A;  2LAE A;  3H1Z A;  2MZ8 A;  2NOF A;  1TBP A;  1EBM A;  1YTB A;  3N89 A;  3ULX A;  2XHI A;  2NOE A;  1JFI C;  1KYD A;  1UT4 A;  1CDW A;  4ROD B;  3HS9 A;  1YQK A;  1NVP A;  1LWY A;  1RM1 A;  4Q11 A;  4B0A A;  1QN3 A;  2D0C A;  4ROE B;  2NOB A;  1QN9 A;  1VOL B;  1MP9 A;  1YQR A;  1KYU A;  2IV8 A;  1FN7 A;  3OST A;  1QN7 A;  2NOZ A;  1AIS A;  1QNB A;  2MJ7 A;  2HZM A;  3ASM A;  3OSM A;  1M3H A;  1N39 A;  2FGT A;  1R4X A;  3SNS A;  1YQM A;  3IH7 A;  4ROC B;  3HS8 A;  1QN5 A;  2Z8U A;  5IYD P;  1QNA A;  1VOK A;  3RPJ A;  1M3Q A;  3DPT A;  3EIK A;  1QTP A;  4DUL A;  1VTL E;  1KY6 A;  1TBA B;  1KY7 A;  1D3U A;  3KRM A;  3OC3 C;  1KYF A;  2D0B A;  4EJZ A;  2G30 A;  1C9B B;  2I5W A;  2HZS A;  1KO9 A;  4PY5 A;  3F0Z A;  1NGM A;  1QN8 A;  1LWV A;  5IYB P;  1YQL A;  2NOL A;  1N3A A;  5IYC P;  3VN5 A;  1YTF A;  2IV9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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