1TGHA

Tata binding protein (tbp)/dna complex
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
180
structure length
180
Chain Sequence
SGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title How proteins recognize the TATA box.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords DNA (5'-D(*CP*GP*TP*AP*TP*AP*TP*AP*TP*AP*CP*G)-3')
total genus 46
structure length 180
sequence length 180
ec nomenclature
pdb deposition date 1996-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00352 TBP Transcription factor TFIID (or TATA-binding protein, TBP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 1tghA01
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 1tghA02
2IV8A 1TBAB 1KY7A 1MP9A 4PY5A 4B0AA 1QN8A 1QNCA 1NGMA 1YTFA 5IYBP 1VTLE 1QN3A 1PCZA 3OCIA 1YTBA 1NH2A 1TGHA 2D0BA 3EIKA 1D3UA 1VOLB 1KYUA 2G30A 1NVPA 1VOKA 1QN5A 2Z8UA 3HS9A 1PZDA 1QTSA 1QTPA 1W80A 1QNBA 1QNAA 3H1ZA 1AISA 1QN4A 1QN6A 4ROCB 1R4XA 2IV9A 2D0AA 4WZSD 2D0CA 4ROEB 1C9BB 4RODB 1QN9A 1TBPA 1QN7A 3HS8A 1B9KA 1E42A 1JFIC 2MJ7A 1KY6A 1KYDA 1RM1A 2VJ0A 5IYCP 1VTOA 3OC3C 5IYDP 3VN5A 1QNEA 1CDWA 1KYFA 3ASMA
chains in the Genus database with same CATH superfamily
3CWUA 2IV8A 1MP9A 1PCJX 3TDHA 2NOZA 1NGMA 5IYBP 1JDYA 1QN3A 2QRCA 2NVMA 3EIKA 4IL8A 3PDKA 3OSTA 1QTSA 3I3WA 4D7QA 3OLPA 1T6AA 1QNBA 1N39A 2QREA 4TPSA 4EAJA 3D4VA 1QN6A 4ROCB 1R4XA 3CW7A 2NOEA 2DKAA 1WJWA 2OOYA 1N3CA 3N89A 4RODB 1KFQA 1VKLA 3I0WA 1TBPA 2FKFA 1P5GX 3HS8A 1E42A 1MPGA 1PVSA 3DPUA 2V9JA 3RPJA 5F9CA 3KRMA 1XSZA 1V5SA 1KYFA 2QLVA 1Q9UA 1YQKA 1YQRA 4EJZA 3F10A 2HKPA 1KY7A 3OGDA 4QG5A 2QR1A 3ULXA 3ENOC 3OH6A 1M3HA 5AN4A 1VTLE 1PCZA 2HZMA 2YA3A 1NH2A 1TGHA 3IH7A 1D3UA 1KYUA 2G30A 1PZDA 1UT7A 4HJHA 2QRDA 3I0XA 4EAIA 1LWWA 2OOXA 2V8QA 3RSMA 1K35A 3OSMA 2Z0FA 1AISA 1J3MA 4WXAA 1M3QA 1LXTA 1C4GA 2JOIA 1HU0A 2Y8QA 1KFIA 2D0AA 2V92A 4EJYA 2LAEA 2Y8LA 2F7LA 1C9BB 3ENCA 5BMPA 2HZSA 4MRQA 2MZ8A 1RM1A 2JPIA 1VTOA 1QNEA 1DIZA 2NLVA 1YQLA 4WX8A 3ASMA 4CFFA 3DPTA 1TBAB 2H4LX 2R5XA 2NOBA 4B0AA 1QN8A 1QNCA 1YTFA 4C7PA 4EAKA 2FGTA 3OSEA 2DKDA 1LWYA 1VOLB 2NWVA 1M5Q1 1PCMX 2YH5A 2Z8UA 4D7RA 2XHIA 4I8OA 3CWAA 3CWTA 2NOHA 3D7QA 1QNAA 1C47A 2NOIA 2JHNA 1QN4A 3CVSA 1N3AA 4EAGA 3CVTA 4WZSD 1TUOA 2D0CA 2H5AX 4ROEB 1EBMA 2I5WA 2HL9A 2FKMX 3TE5A 1KYDA 2NOLA 5IYDP 3VN5A 2ZFDB 2DKCA 1CDWA 1LWVA 4PY5A 1WQAA 1UT4A 5JMVD 3OCIA 1YTBA 4DULA 2D0BA 1NVPA 1K2YX 1VOKA 2O3OA 4BJUA 2JHJA 3OH9A 1KO9A 3HS9A 1QTPA 1FN7A 1QN5A 1W80A 5KL0A 3H1ZA 4Q11A 1EUVA 2HL8A 3EAYA 3SNSA 1P5DX 2IV9A 2EHBD 3BKQX 3KTUA 5JN5A 3CWSA 2NOFA 2FUVA 3T4NA 1QN9A 4EALA 1QN7A 1B9KA 3PMGA 5HSHA 1JFIC 2MJ7A 1KY6A 3F0ZA 2PWWA 2VJ0A 3C04A 5IYCP 1YQMA 3OC3C 3UW2A 5EPCA 3NA5A 5BMNA 1UL7A
chains in the Genus database with same CATH topology
2IV8A 1MP9A 2NOZA 1NGMA 5IYBP 1QN3A 3EIKA 3OSTA 1QTSA 1QNBA 1N39A 4TPSA 1QN6A 4ROCB 1R4XA 2NOEA 1N3CA 3N89A 4RODB 3I0WA 1TBPA 3HS8A 1E42A 3DPUA 3RPJA 3KRMA 1KYFA 1YQKA 1YQRA 4EJZA 3F10A 1KY7A 3ULXA 1M3HA 5AN4A 1VTLE 1PCZA 2HZMA 1NH2A 1TGHA 3IH7A 1D3UA 1KYUA 2G30A 1PZDA 1UT7A 3I0XA 1LWWA 3OSMA 1AISA 1M3QA 2JOIA 1HU0A 2D0AA 4EJYA 2LAEA 1C9BB 2HZSA 2MZ8A 1RM1A 1VTOA 1QNEA 1YQLA 3ASMA 3DPTA 1TBAB 2NOBA 4B0AA 1QN8A 1QNCA 1YTFA 2FGTA 1LWYA 1VOLB 2XHIA 2Z8UA 2YH5A 4I8OA 2NOHA 1QNAA 2NOIA 1QN4A 1N3AA 4WZSD 2D0CA 4ROEB 1EBMA 2I5WA 1KYDA 2NOLA 5IYDP 3VN5A 1CDWA 1LWVA 1UT4A 3OCIA 1YTBA 4DULA 2D0BA 1NVPA 1VOKA 2O3OA 1QN5A 1FN7A 1KO9A 3HS9A 1QTPA 1W80A 3H1ZA 4Q11A 3SNSA 2IV9A 3KTUA 2NOFA 1QN9A 1QN7A 1B9KA 1JFIC 2MJ7A 1KY6A 3F0ZA 2VJ0A 5IYCP 1YQMA 3OC3C 4PY5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IV8 A;  1TBA B;  1KY7 A;  1MP9 A;  4PY5 A;  4B0A A;  1QN8 A;  1QNC A;  1NGM A;  1YTF A;  5IYB P;  1VTL E;  1QN3 A;  1PCZ A;  3OCI A;  1YTB A;  1NH2 A;  1TGH A;  2D0B A;  3EIK A;  1D3U A;  1VOL B;  1KYU A;  2G30 A;  1NVP A;  1VOK A;  1QN5 A;  2Z8U A;  3HS9 A;  1PZD A;  1QTS A;  1QTP A;  1W80 A;  1QNB A;  1QNA A;  3H1Z A;  1AIS A;  1QN4 A;  1QN6 A;  4ROC B;  1R4X A;  2IV9 A;  2D0A A;  4WZS D;  2D0C A;  4ROE B;  1C9B B;  4ROD B;  1QN9 A;  1TBP A;  1QN7 A;  3HS8 A;  1B9K A;  1E42 A;  1JFI C;  2MJ7 A;  1KY6 A;  1KYD A;  1RM1 A;  2VJ0 A;  5IYC P;  1VTO A;  3OC3 C;  5IYD P;  3VN5 A;  1QNE A;  1CDW A;  1KYF A;  3ASM A; 
#chains in the Genus database with same CATH topology
 3CWU A;  2IV8 A;  1MP9 A;  1PCJ X;  3TDH A;  2NOZ A;  1NGM A;  5IYB P;  1JDY A;  1QN3 A;  2QRC A;  2NVM A;  3EIK A;  4IL8 A;  3PDK A;  3OST A;  1QTS A;  3I3W A;  4D7Q A;  3OLP A;  1T6A A;  1QNB A;  1N39 A;  2QRE A;  4TPS A;  4EAJ A;  3D4V A;  1QN6 A;  4ROC B;  1R4X A;  3CW7 A;  2NOE A;  2DKA A;  1WJW A;  2OOY A;  1N3C A;  3N89 A;  4ROD B;  1KFQ A;  1VKL A;  3I0W A;  1TBP A;  2FKF A;  1P5G X;  3HS8 A;  1E42 A;  1MPG A;  1PVS A;  3DPU A;  2V9J A;  3RPJ A;  5F9C A;  3KRM A;  1XSZ A;  1V5S A;  1KYF A;  2QLV A;  1Q9U A;  1YQK A;  1YQR A;  4EJZ A;  3F10 A;  2HKP A;  1KY7 A;  3OGD A;  4QG5 A;  2QR1 A;  3ULX A;  3ENO C;  3OH6 A;  1M3H A;  5AN4 A;  1VTL E;  1PCZ A;  2HZM A;  2YA3 A;  1NH2 A;  1TGH A;  3IH7 A;  1D3U A;  1KYU A;  2G30 A;  1PZD A;  1UT7 A;  4HJH A;  2QRD A;  3I0X A;  4EAI A;  1LWW A;  2OOX A;  2V8Q A;  3RSM A;  1K35 A;  3OSM A;  2Z0F A;  1AIS A;  1J3M A;  4WXA A;  1M3Q A;  1LXT A;  1C4G A;  2JOI A;  1HU0 A;  2Y8Q A;  1KFI A;  2D0A A;  2V92 A;  4EJY A;  2LAE A;  2Y8L A;  2F7L A;  1C9B B;  3ENC A;  5BMP A;  2HZS A;  4MRQ A;  2MZ8 A;  1RM1 A;  2JPI A;  1VTO A;  1QNE A;  1DIZ A;  2NLV A;  1YQL A;  4WX8 A;  3ASM A;  4CFF A;  3DPT A;  1TBA B;  2H4L X;  2R5X A;  2NOB A;  4B0A A;  1QN8 A;  1QNC A;  1YTF A;  4C7P A;  4EAK A;  2FGT A;  3OSE A;  2DKD A;  1LWY A;  1VOL B;  2NWV A;  1M5Q 1;  1PCM X;  2YH5 A;  2Z8U A;  4D7R A;  2XHI A;  4I8O A;  3CWA A;  3CWT A;  2NOH A;  3D7Q A;  1QNA A;  1C47 A;  2NOI A;  2JHN A;  1QN4 A;  3CVS A;  1N3A A;  4EAG A;  3CVT A;  4WZS D;  1TUO A;  2D0C A;  2H5A X;  4ROE B;  1EBM A;  2I5W A;  2HL9 A;  2FKM X;  3TE5 A;  1KYD A;  2NOL A;  5IYD P;  3VN5 A;  2ZFD B;  2DKC A;  1CDW A;  1LWV A;  4PY5 A;  1WQA A;  1UT4 A;  5JMV D;  3OCI A;  1YTB A;  4DUL A;  2D0B A;  1NVP A;  1K2Y X;  1VOK A;  2O3O A;  4BJU A;  2JHJ A;  3OH9 A;  1KO9 A;  3HS9 A;  1QTP A;  1FN7 A;  1QN5 A;  1W80 A;  5KL0 A;  3H1Z A;  4Q11 A;  1EUV A;  2HL8 A;  3EAY A;  3SNS A;  1P5D X;  2IV9 A;  2EHB D;  3BKQ X;  3KTU A;  5JN5 A;  3CWS A;  2NOF A;  2FUV A;  3T4N A;  1QN9 A;  4EAL A;  1QN7 A;  1B9K A;  3PMG A;  5HSH A;  1JFI C;  2MJ7 A;  1KY6 A;  3F0Z A;  2PWW A;  2VJ0 A;  3C04 A;  5IYC P;  1YQM A;  3OC3 C;  3UW2 A;  5EPC A;  3NA5 A;  5BMN A;  1UL7 A; 
#chains in the Genus database with same CATH homology
 2IV8 A;  1MP9 A;  2NOZ A;  1NGM A;  5IYB P;  1QN3 A;  3EIK A;  3OST A;  1QTS A;  1QNB A;  1N39 A;  4TPS A;  1QN6 A;  4ROC B;  1R4X A;  2NOE A;  1N3C A;  3N89 A;  4ROD B;  3I0W A;  1TBP A;  3HS8 A;  1E42 A;  3DPU A;  3RPJ A;  3KRM A;  1KYF A;  1YQK A;  1YQR A;  4EJZ A;  3F10 A;  1KY7 A;  3ULX A;  1M3H A;  5AN4 A;  1VTL E;  1PCZ A;  2HZM A;  1NH2 A;  1TGH A;  3IH7 A;  1D3U A;  1KYU A;  2G30 A;  1PZD A;  1UT7 A;  3I0X A;  1LWW A;  3OSM A;  1AIS A;  1M3Q A;  2JOI A;  1HU0 A;  2D0A A;  4EJY A;  2LAE A;  1C9B B;  2HZS A;  2MZ8 A;  1RM1 A;  1VTO A;  1QNE A;  1YQL A;  3ASM A;  3DPT A;  1TBA B;  2NOB A;  4B0A A;  1QN8 A;  1QNC A;  1YTF A;  2FGT A;  1LWY A;  1VOL B;  2XHI A;  2Z8U A;  2YH5 A;  4I8O A;  2NOH A;  1QNA A;  2NOI A;  1QN4 A;  1N3A A;  4WZS D;  2D0C A;  4ROE B;  1EBM A;  2I5W A;  1KYD A;  2NOL A;  5IYD P;  3VN5 A;  1CDW A;  1LWV A;  1UT4 A;  3OCI A;  1YTB A;  4DUL A;  2D0B A;  1NVP A;  1VOK A;  2O3O A;  1QN5 A;  1FN7 A;  1KO9 A;  3HS9 A;  1QTP A;  1W80 A;  3H1Z A;  4Q11 A;  3SNS A;  2IV9 A;  3KTU A;  2NOF A;  1QN9 A;  1QN7 A;  1B9K A;  1JFI C;  2MJ7 A;  1KY6 A;  3F0Z A;  2VJ0 A;  5IYC P;  1YQM A;  3OC3 C;  4PY5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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