1VTLE

Co-crystal structure of tbp recognizing the minor groove of a tata element
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
186
structure length
186
Chain Sequence
DLSKHPSGIVPTLQNIVSTVNLDCKLDLKAIALQARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVCTGAKSEDFSKMAARKYARIVQKLGFPAKFKDFKIQNIVGSCDVKFPIRLEGLAYSHAAFSSYEPELFPGLIYRMKVPKIVLLIFVSGKIVITGAKMRDETYKAFENIYPVLSEFRKI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Co-Crystal Structure of TBP Recognizing the Minor Groove of a TATA Element
pubmed doi rcsb
molecule tags Transcription/dna
molecule keywords DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*A)-3')
total genus 46
structure length 186
sequence length 186
chains with identical sequence F
ec nomenclature
pdb deposition date 1993-12-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00352 TBP Transcription factor TFIID (or TATA-binding protein, TBP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 1vtlE01
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 1vtlE02
2D0BA 3H1ZA 1W80A 4ROEB 2IV9A 1KY6A 1AISA 1QNAA 1PZDA 1QN6A 2VJ0A 1MP9A 1QTPA 4WZSD 2MJ7A 1VOLB 1QNEA 2D0AA 1PCZA 1JFIC 1QNBA 1KYFA 1KYUA 2D0CA 1KY7A 3OCIA 1YTBA 3HS8A 1E42A 1NVPA 1NH2A 3VN5A 5IYBP 1VTLE 1RM1A 1YTFA 1TBPA 1QN4A 1QTSA 1C9BB 1QN3A 1R4XA 3OC3C 1NGMA 2IV8A 1CDWA 1VTOA 3ASMA 1TBAB 2G30A 1QN5A 1D3UA 1QNCA 5IYDP 1B9KA 1QN7A 4RODB 1QN9A 3EIKA 1KYDA 4ROCB 4B0AA 1QN8A 3HS9A 1TGHA 5IYCP 4PY5A 1VOKA 2Z8UA
chains in the Genus database with same CATH superfamily
2D0BA 1W80A 4ROEB 1C47A 1KY6A 2JOIA 2QLVA 1M3HA 1AISA 2PWWA 4EALA 1LWWA 3I0XA 1LWYA 2V92A 3KTUA 2ZFDB 1VKLA 3NA5A 4IL8A 2D0AA 3OSMA 4EAGA 1JFIC 2NOHA 1Q9UA 3DPTA 3OCIA 5AN4A 3KRMA 4WX8A 1P5GX 3D4VA 4EAIA 1YTFA 3CWSA 1YQRA 1EUVA 2NOFA 2EHBD 3SNSA 3D7QA 1M5Q1 3CVSA 2LAEA 3IH7A 2IV8A 4C7PA 2QREA 3ASMA 2G30A 2YH5A 4CFFA 1QN5A 1D3UA 1K35A 4Q11A 4RODB 2JHNA 1TGHA 1N3CA 1YQLA 4PY5A 1LXTA 3ENCA 3BKQX 2Z8UA 1M3QA 5KL0A 2JHJA 2IV9A 5JN5A 3ULXA 1N39A 2NOLA 1PCJX 3F0ZA 2R5XA 3OSTA 1UL7A 2NOIA 2O3OA 1KFQA 4WZSD 3CW7A 1PCZA 3DPUA 2NWVA 3UW2A 1JDYA 1LWVA 1YTBA 3TDHA 1E42A 4QG5A 4EAKA 5F9CA 1NH2A 1RM1A 2NOBA 1TBPA 1QTSA 3OSEA 2Y8QA 2V8QA 2QRDA 2F7LA 1TUOA 2Y8LA 1QNCA 1B9KA 4B0AA 4D7QA 1UT7A 1DIZA 3HS9A 3RPJA 5IYCP 1KFIA 2NOEA 1V5SA 3H1ZA 1WJWA 1P5DX 4EAJA 1QNAA 4EJZA 4BJUA 1PZDA 1QN6A 1MP9A 1QTPA 3I3WA 3CWAA 2QR1A 2MJ7A 1WQAA 1VOLB 1MPGA 3CWUA 1KYFA 2DKCA 1PCMX 2FUVA 1KYUA 3EAYA 3CWTA 3OLPA 3CVTA 2MZ8A 3VN5A 5IYBP 5JMVD 2DKDA 3OH6A 3N89A 4TPSA 2HZSA 1C9BB 1QN3A 1R4XA 2Z0FA 3OC3C 1YQKA 2NLVA 5HSHA 1TBAB 2HL9A 3T4NA 1YQMA 1QN9A 1KYDA 2HKPA 4HJHA 5EPCA 1EBMA 1QN8A 2JPIA 2HZMA 2XHIA 1PVSA 1N3AA 5BMPA 2VJ0A 4I8OA 2I5WA 2YA3A 2NOZA 1QNEA 1T6AA 3TE5A 2OOXA 1QNBA 4D7RA 2V9JA 2OOYA 2D0CA 3F10A 1KY7A 3C04A 1XSZA 4EJYA 3HS8A 1C4GA 1HU0A 4DULA 1FN7A 1NVPA 1VTLE 1QN4A 2DKAA 3OGDA 4WXAA 3OH9A 1K2YX 2FGTA 2H4LX 1NGMA 2H5AX 2HL8A 1CDWA 1VTOA 3ENOC 3PMGA 5BMNA 2NVMA 5IYDP 3RSMA 1J3MA 1UT4A 2FKMX 1QN7A 3EIKA 3PDKA 2FKFA 4ROCB 3I0WA 4MRQA 1KO9A 2QRCA 1VOKA
chains in the Genus database with same CATH topology
2D0BA 1W80A 4ROEB 1KY6A 2JOIA 1AISA 1M3HA 1LWWA 3I0XA 1LWYA 3KTUA 2D0AA 3OSMA 1JFIC 2NOHA 3DPTA 3OCIA 5AN4A 3KRMA 1YTFA 1YQRA 2NOFA 3SNSA 2LAEA 3IH7A 2IV8A 3ASMA 2G30A 2YH5A 1QN5A 1D3UA 4Q11A 4RODB 1TGHA 1N3CA 1YQLA 4PY5A 2Z8UA 1M3QA 2IV9A 2NOLA 3ULXA 1N39A 2NOIA 3F0ZA 3OSTA 2O3OA 4WZSD 1PCZA 3DPUA 1LWVA 1YTBA 1E42A 1NH2A 1RM1A 2NOBA 1TBPA 1QTSA 1QNCA 1B9KA 4B0AA 1UT7A 3HS9A 3RPJA 5IYCP 2NOEA 3H1ZA 4EJZA 1QNAA 1PZDA 1QN6A 1MP9A 1QTPA 2MJ7A 1VOLB 1KYFA 1KYUA 2MZ8A 3VN5A 5IYBP 3N89A 4TPSA 2HZSA 1C9BB 1QN3A 1R4XA 1YQKA 3OC3C 1TBAB 1YQMA 1QN9A 1KYDA 1QN8A 1EBMA 2HZMA 2XHIA 1N3AA 2VJ0A 4I8OA 2I5WA 2NOZA 1QNEA 1QNBA 3F10A 2D0CA 4EJYA 1KY7A 3HS8A 1HU0A 4DULA 1FN7A 1NVPA 1VTLE 1QN4A 2FGTA 1NGMA 1CDWA 1VTOA 5IYDP 1UT4A 1QN7A 3EIKA 4ROCB 3I0WA 1KO9A 1VOKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2D0B A;  3H1Z A;  1W80 A;  4ROE B;  2IV9 A;  1KY6 A;  1AIS A;  1QNA A;  1PZD A;  1QN6 A;  2VJ0 A;  1MP9 A;  1QTP A;  4WZS D;  2MJ7 A;  1VOL B;  1QNE A;  2D0A A;  1PCZ A;  1JFI C;  1QNB A;  1KYF A;  1KYU A;  2D0C A;  1KY7 A;  3OCI A;  1YTB A;  3HS8 A;  1E42 A;  1NVP A;  1NH2 A;  3VN5 A;  5IYB P;  1VTL E;  1RM1 A;  1YTF A;  1TBP A;  1QN4 A;  1QTS A;  1C9B B;  1QN3 A;  1R4X A;  3OC3 C;  1NGM A;  2IV8 A;  1CDW A;  1VTO A;  3ASM A;  1TBA B;  2G30 A;  1QN5 A;  1D3U A;  1QNC A;  5IYD P;  1B9K A;  1QN7 A;  4ROD B;  1QN9 A;  3EIK A;  1KYD A;  4ROC B;  4B0A A;  1QN8 A;  3HS9 A;  1TGH A;  5IYC P;  4PY5 A;  1VOK A;  2Z8U A; 
#chains in the Genus database with same CATH topology
 2D0B A;  1W80 A;  4ROE B;  1C47 A;  1KY6 A;  2JOI A;  2QLV A;  1M3H A;  1AIS A;  2PWW A;  4EAL A;  1LWW A;  3I0X A;  1LWY A;  2V92 A;  3KTU A;  2ZFD B;  1VKL A;  3NA5 A;  4IL8 A;  2D0A A;  3OSM A;  4EAG A;  1JFI C;  2NOH A;  1Q9U A;  3DPT A;  3OCI A;  5AN4 A;  3KRM A;  4WX8 A;  1P5G X;  3D4V A;  4EAI A;  1YTF A;  3CWS A;  1YQR A;  1EUV A;  2NOF A;  2EHB D;  3SNS A;  3D7Q A;  1M5Q 1;  3CVS A;  2LAE A;  3IH7 A;  2IV8 A;  4C7P A;  2QRE A;  3ASM A;  2G30 A;  2YH5 A;  4CFF A;  1QN5 A;  1D3U A;  1K35 A;  4Q11 A;  4ROD B;  2JHN A;  1TGH A;  1N3C A;  1YQL A;  4PY5 A;  1LXT A;  3ENC A;  3BKQ X;  2Z8U A;  1M3Q A;  5KL0 A;  2JHJ A;  2IV9 A;  5JN5 A;  3ULX A;  1N39 A;  2NOL A;  1PCJ X;  3F0Z A;  2R5X A;  3OST A;  1UL7 A;  2NOI A;  2O3O A;  1KFQ A;  4WZS D;  3CW7 A;  1PCZ A;  3DPU A;  2NWV A;  3UW2 A;  1JDY A;  1LWV A;  1YTB A;  3TDH A;  1E42 A;  4QG5 A;  4EAK A;  5F9C A;  1NH2 A;  1RM1 A;  2NOB A;  1TBP A;  1QTS A;  3OSE A;  2Y8Q A;  2V8Q A;  2QRD A;  2F7L A;  1TUO A;  2Y8L A;  1QNC A;  1B9K A;  4B0A A;  4D7Q A;  1UT7 A;  1DIZ A;  3HS9 A;  3RPJ A;  5IYC P;  1KFI A;  2NOE A;  1V5S A;  3H1Z A;  1WJW A;  1P5D X;  4EAJ A;  1QNA A;  4EJZ A;  4BJU A;  1PZD A;  1QN6 A;  1MP9 A;  1QTP A;  3I3W A;  3CWA A;  2QR1 A;  2MJ7 A;  1WQA A;  1VOL B;  1MPG A;  3CWU A;  1KYF A;  2DKC A;  1PCM X;  2FUV A;  1KYU A;  3EAY A;  3CWT A;  3OLP A;  3CVT A;  2MZ8 A;  3VN5 A;  5IYB P;  5JMV D;  2DKD A;  3OH6 A;  3N89 A;  4TPS A;  2HZS A;  1C9B B;  1QN3 A;  1R4X A;  2Z0F A;  3OC3 C;  1YQK A;  2NLV A;  5HSH A;  1TBA B;  2HL9 A;  3T4N A;  1YQM A;  1QN9 A;  1KYD A;  2HKP A;  4HJH A;  5EPC A;  1EBM A;  1QN8 A;  2JPI A;  2HZM A;  2XHI A;  1PVS A;  1N3A A;  5BMP A;  2VJ0 A;  4I8O A;  2I5W A;  2YA3 A;  2NOZ A;  1QNE A;  1T6A A;  3TE5 A;  2OOX A;  1QNB A;  4D7R A;  2V9J A;  2OOY A;  2D0C A;  3F10 A;  1KY7 A;  3C04 A;  1XSZ A;  4EJY A;  3HS8 A;  1C4G A;  1HU0 A;  4DUL A;  1FN7 A;  1NVP A;  1VTL E;  1QN4 A;  2DKA A;  3OGD A;  4WXA A;  3OH9 A;  1K2Y X;  2FGT A;  2H4L X;  1NGM A;  2H5A X;  2HL8 A;  1CDW A;  1VTO A;  3ENO C;  3PMG A;  5BMN A;  2NVM A;  5IYD P;  3RSM A;  1J3M A;  1UT4 A;  2FKM X;  1QN7 A;  3EIK A;  3PDK A;  2FKF A;  4ROC B;  3I0W A;  4MRQ A;  1KO9 A;  2QRC A;  1VOK A; 
#chains in the Genus database with same CATH homology
 2D0B A;  1W80 A;  4ROE B;  1KY6 A;  2JOI A;  1AIS A;  1M3H A;  1LWW A;  3I0X A;  1LWY A;  3KTU A;  2D0A A;  3OSM A;  1JFI C;  2NOH A;  3DPT A;  3OCI A;  5AN4 A;  3KRM A;  1YTF A;  1YQR A;  2NOF A;  3SNS A;  2LAE A;  3IH7 A;  2IV8 A;  3ASM A;  2G30 A;  2YH5 A;  1QN5 A;  1D3U A;  4Q11 A;  4ROD B;  1TGH A;  1N3C A;  1YQL A;  4PY5 A;  2Z8U A;  1M3Q A;  2IV9 A;  2NOL A;  3ULX A;  1N39 A;  2NOI A;  3F0Z A;  3OST A;  2O3O A;  4WZS D;  1PCZ A;  3DPU A;  1LWV A;  1YTB A;  1E42 A;  1NH2 A;  1RM1 A;  2NOB A;  1TBP A;  1QTS A;  1QNC A;  1B9K A;  4B0A A;  1UT7 A;  3HS9 A;  3RPJ A;  5IYC P;  2NOE A;  3H1Z A;  4EJZ A;  1QNA A;  1PZD A;  1QN6 A;  1MP9 A;  1QTP A;  2MJ7 A;  1VOL B;  1KYF A;  1KYU A;  2MZ8 A;  3VN5 A;  5IYB P;  3N89 A;  4TPS A;  2HZS A;  1C9B B;  1QN3 A;  1R4X A;  1YQK A;  3OC3 C;  1TBA B;  1YQM A;  1QN9 A;  1KYD A;  1QN8 A;  1EBM A;  2HZM A;  2XHI A;  1N3A A;  2VJ0 A;  4I8O A;  2I5W A;  2NOZ A;  1QNE A;  1QNB A;  3F10 A;  2D0C A;  4EJY A;  1KY7 A;  3HS8 A;  1HU0 A;  4DUL A;  1FN7 A;  1NVP A;  1VTL E;  1QN4 A;  2FGT A;  1NGM A;  1CDW A;  1VTO A;  5IYD P;  1UT4 A;  1QN7 A;  3EIK A;  4ROC B;  3I0W A;  1KO9 A;  1VOK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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