1CDWA

Human tbp core domain complexed with dna
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
179
structure length
179
Chain Sequence
SGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEENSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a human TATA box-binding protein/TATA element complex.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords DNA (5'-D(*CP*TP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*CP*TP*G)-3
total genus 45
structure length 179
sequence length 179
ec nomenclature
pdb deposition date 1996-04-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00352 TBP Transcription factor TFIID (or TATA-binding protein, TBP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 1cdwA01
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 1cdwA02
3EIKA 1NVPA 2D0AA 1QNAA 1VOLB 1KY7A 2IV9A 2VJ0A 3VN5A 1AISA 1QN9A 5IYCP 1QTSA 1PCZA 2MJ7A 1QN6A 1E42A 1KYDA 1VOKA 4ROEB 1TBAB 1QN4A 1JFIC 2IV8A 4WZSD 3OC3C 4B0AA 3OCIA 1TBPA 1VTOA 1QTPA 5IYBP 1QNCA 3H1ZA 3ASMA 1C9BB 1KYFA 1VTLE 1QNEA 1MP9A 1RM1A 1QN3A 1NGMA 1YTFA 1TGHA 1CDWA 1YTBA 4ROCB 1W80A 2D0BA 2D0CA 3HS8A 3HS9A 1PZDA 1NH2A 1D3UA 5IYDP 4PY5A 1KY6A 2G30A 1QN5A 4RODB 1KYUA 2Z8UA 1QN7A 1B9KA 1R4XA 1QNBA 1QN8A
chains in the Genus database with same CATH superfamily
3KRMA 3OSEA 4IL8A 3NA5A 4D7QA 3KTUA 2JHNA 3CWSA 5JMVD 3F10A 2FKFA 2QLVA 3BKQX 3UW2A 2YA3A 4QG5A 5F9CA 1QTPA 5IYBP 3D4VA 2QRDA 1P5GX 3TDHA 1RM1A 3CWUA 1CDWA 1YTBA 1UT7A 1W80A 3ULXA 5HSHA 2D0CA 2Y8QA 1K35A 4HJHA 1NH2A 1D3UA 1KFQA 2R5XA 1M3QA 1N3AA 4EJZA 2NOFA 1JDYA 3OH6A 1YQMA 1V5SA 2NOZA 3EIKA 1KY7A 5BMPA 4EJYA 1DIZA 1AISA 2Y8LA 1QN9A 1QTSA 1PCZA 2HZMA 3I3WA 1E42A 3N89A 3EAYA 4ROEB 1N3CA 1YQKA 1QN4A 1JFIC 3D7QA 2DKAA 4B0AA 1LWVA 1PVSA 3CVSA 3ENOC 1FN7A 1C47A 1C9BB 1VTLE 1QNEA 1YTFA 2HL9A 1PCMX 2PWWA 1NGMA 1QN3A 1TGHA 5KL0A 2FUVA 1N39A 3T4NA 1KO9A 1PZDA 1Q9UA 5IYDP 4C7PA 2F7LA 1LWYA 4PY5A 2JHJA 3CWTA 2QR1A 1KYUA 3SNSA 4EAJA 4TPSA 5JN5A 1B9KA 3HS8A 1YQLA 3I0WA 3RPJA 2DKDA 1M3HA 1LWWA 2D0AA 4WXAA 2NOIA 1VOLB 1MPGA 3CW7A 2EHBD 2IV9A 2VJ0A 3PMGA 3RSMA 4BJUA 1KYDA 1VOKA 2OOYA 4I8OA 3PDKA 1TBAB 2IV8A 4WZSD 3OC3C 2NOEA 2FGTA 1UT4A 2QRCA 4MRQA 5AN4A 2NOLA 3OCIA 4DULA 1VTOA 3OSTA 1J3MA 1PCJX 1M5Q1 1QNCA 3ASMA 3OH9A 3DPTA 1P5DX 2QREA 2LAEA 2V92A 2NVMA 4EAGA 4Q11A 2XHIA 4EALA 2FKMX 4WX8A 5EPCA 3CVTA 4ROCB 2I5WA 2NOHA 2D0BA 3HS9A 2HZSA 1TUOA 3OLPA 2G30A 3F0ZA 2JOIA 4RODB 1T6AA 2Z0FA 3CWAA 1QN5A 2Z8UA 1R4XA 1QNBA 1QN8A 4EAIA 3IH7A 3ENCA 3C04A 5BMNA 2ZFDB 1NVPA 1LXTA 1QNAA 3OGDA 2NOBA 2V9JA 2HL8A 2V8QA 3VN5A 5IYCP 1QN6A 2MJ7A 2H5AX 3OSMA 3TE5A 2NWVA 1YQRA 2JPIA 1C4GA 2YH5A 1WQAA 1TBPA 1K2YX 3H1ZA 2DKCA 1KYFA 1WJWA 1MP9A 3DPUA 1KFIA 1XSZA 2HKPA 1HU0A 2MZ8A 1VKLA 4CFFA 3I0XA 2NLVA 4EAKA 1EUVA 1KY6A 1UL7A 1QN7A 4D7RA 2H4LX 1EBMA 2O3OA 2OOXA
chains in the Genus database with same CATH topology
3KRMA 3KTUA 3F10A 1QTPA 5IYBP 1RM1A 1CDWA 1YTBA 1UT7A 1W80A 3ULXA 2D0CA 1NH2A 1D3UA 1M3QA 1N3AA 4EJZA 2NOFA 1YQMA 2NOZA 3EIKA 1KY7A 4EJYA 1AISA 1QN9A 1QTSA 1PCZA 2HZMA 3N89A 1E42A 4ROEB 1N3CA 1YQKA 1QN4A 1JFIC 4B0AA 1LWVA 1FN7A 1C9BB 1VTLE 1QNEA 1YTFA 1QN3A 1NGMA 1TGHA 1N39A 1KO9A 1PZDA 5IYDP 1LWYA 4PY5A 3SNSA 1KYUA 4TPSA 1B9KA 3HS8A 1YQLA 3I0WA 3RPJA 1M3HA 1LWWA 2D0AA 2NOIA 1VOLB 2IV9A 2VJ0A 1KYDA 1VOKA 4I8OA 1TBAB 2IV8A 4WZSD 3OC3C 2NOEA 2FGTA 1UT4A 2NOLA 5AN4A 3OCIA 4DULA 1VTOA 3OSTA 1QNCA 3ASMA 3DPTA 2LAEA 4Q11A 2XHIA 4ROCB 2I5WA 2NOHA 2D0BA 3HS9A 2HZSA 2G30A 3F0ZA 2JOIA 4RODB 1QN5A 2Z8UA 1R4XA 1QNBA 1QN8A 3IH7A 1NVPA 1QNAA 2NOBA 3VN5A 5IYCP 1QN6A 2MJ7A 3OSMA 1YQRA 2YH5A 1TBPA 3H1ZA 1KYFA 1MP9A 3DPUA 1HU0A 2MZ8A 3I0XA 1KY6A 1QN7A 2O3OA 1EBMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EIK A;  1NVP A;  2D0A A;  1QNA A;  1VOL B;  1KY7 A;  2IV9 A;  2VJ0 A;  3VN5 A;  1AIS A;  1QN9 A;  5IYC P;  1QTS A;  1PCZ A;  2MJ7 A;  1QN6 A;  1E42 A;  1KYD A;  1VOK A;  4ROE B;  1TBA B;  1QN4 A;  1JFI C;  2IV8 A;  4WZS D;  3OC3 C;  4B0A A;  3OCI A;  1TBP A;  1VTO A;  1QTP A;  5IYB P;  1QNC A;  3H1Z A;  3ASM A;  1C9B B;  1KYF A;  1VTL E;  1QNE A;  1MP9 A;  1RM1 A;  1QN3 A;  1NGM A;  1YTF A;  1TGH A;  1CDW A;  1YTB A;  4ROC B;  1W80 A;  2D0B A;  2D0C A;  3HS8 A;  3HS9 A;  1PZD A;  1NH2 A;  1D3U A;  5IYD P;  4PY5 A;  1KY6 A;  2G30 A;  1QN5 A;  4ROD B;  1KYU A;  2Z8U A;  1QN7 A;  1B9K A;  1R4X A;  1QNB A;  1QN8 A; 
#chains in the Genus database with same CATH topology
 3KRM A;  3OSE A;  4IL8 A;  3NA5 A;  4D7Q A;  3KTU A;  2JHN A;  3CWS A;  5JMV D;  3F10 A;  2FKF A;  2QLV A;  3BKQ X;  3UW2 A;  2YA3 A;  4QG5 A;  5F9C A;  1QTP A;  5IYB P;  3D4V A;  2QRD A;  1P5G X;  3TDH A;  1RM1 A;  3CWU A;  1CDW A;  1YTB A;  1UT7 A;  1W80 A;  3ULX A;  5HSH A;  2D0C A;  2Y8Q A;  1K35 A;  4HJH A;  1NH2 A;  1D3U A;  1KFQ A;  2R5X A;  1M3Q A;  1N3A A;  4EJZ A;  2NOF A;  1JDY A;  3OH6 A;  1YQM A;  1V5S A;  2NOZ A;  3EIK A;  1KY7 A;  5BMP A;  4EJY A;  1DIZ A;  1AIS A;  2Y8L A;  1QN9 A;  1QTS A;  1PCZ A;  2HZM A;  3I3W A;  1E42 A;  3N89 A;  3EAY A;  4ROE B;  1N3C A;  1YQK A;  1QN4 A;  1JFI C;  3D7Q A;  2DKA A;  4B0A A;  1LWV A;  1PVS A;  3CVS A;  3ENO C;  1FN7 A;  1C47 A;  1C9B B;  1VTL E;  1QNE A;  1YTF A;  2HL9 A;  1PCM X;  2PWW A;  1NGM A;  1QN3 A;  1TGH A;  5KL0 A;  2FUV A;  1N39 A;  3T4N A;  1KO9 A;  1PZD A;  1Q9U A;  5IYD P;  4C7P A;  2F7L A;  1LWY A;  4PY5 A;  2JHJ A;  3CWT A;  2QR1 A;  1KYU A;  3SNS A;  4EAJ A;  4TPS A;  5JN5 A;  1B9K A;  3HS8 A;  1YQL A;  3I0W A;  3RPJ A;  2DKD A;  1M3H A;  1LWW A;  2D0A A;  4WXA A;  2NOI A;  1VOL B;  1MPG A;  3CW7 A;  2EHB D;  2IV9 A;  2VJ0 A;  3PMG A;  3RSM A;  4BJU A;  1KYD A;  1VOK A;  2OOY A;  4I8O A;  3PDK A;  1TBA B;  2IV8 A;  4WZS D;  3OC3 C;  2NOE A;  2FGT A;  1UT4 A;  2QRC A;  4MRQ A;  5AN4 A;  2NOL A;  3OCI A;  4DUL A;  1VTO A;  3OST A;  1J3M A;  1PCJ X;  1M5Q 1;  1QNC A;  3ASM A;  3OH9 A;  3DPT A;  1P5D X;  2QRE A;  2LAE A;  2V92 A;  2NVM A;  4EAG A;  4Q11 A;  2XHI A;  4EAL A;  2FKM X;  4WX8 A;  5EPC A;  3CVT A;  4ROC B;  2I5W A;  2NOH A;  2D0B A;  3HS9 A;  2HZS A;  1TUO A;  3OLP A;  2G30 A;  3F0Z A;  2JOI A;  4ROD B;  1T6A A;  2Z0F A;  3CWA A;  1QN5 A;  2Z8U A;  1R4X A;  1QNB A;  1QN8 A;  4EAI A;  3IH7 A;  3ENC A;  3C04 A;  5BMN A;  2ZFD B;  1NVP A;  1LXT A;  1QNA A;  3OGD A;  2NOB A;  2V9J A;  2HL8 A;  2V8Q A;  3VN5 A;  5IYC P;  1QN6 A;  2MJ7 A;  2H5A X;  3OSM A;  3TE5 A;  2NWV A;  1YQR A;  2JPI A;  1C4G A;  2YH5 A;  1WQA A;  1TBP A;  1K2Y X;  3H1Z A;  2DKC A;  1KYF A;  1WJW A;  1MP9 A;  3DPU A;  1KFI A;  1XSZ A;  2HKP A;  1HU0 A;  2MZ8 A;  1VKL A;  4CFF A;  3I0X A;  2NLV A;  4EAK A;  1EUV A;  1KY6 A;  1UL7 A;  1QN7 A;  4D7R A;  2H4L X;  1EBM A;  2O3O A;  2OOX A; 
#chains in the Genus database with same CATH homology
 3KRM A;  3KTU A;  3F10 A;  1QTP A;  5IYB P;  1RM1 A;  1CDW A;  1YTB A;  1UT7 A;  1W80 A;  3ULX A;  2D0C A;  1NH2 A;  1D3U A;  1M3Q A;  1N3A A;  4EJZ A;  2NOF A;  1YQM A;  2NOZ A;  3EIK A;  1KY7 A;  4EJY A;  1AIS A;  1QN9 A;  1QTS A;  1PCZ A;  2HZM A;  3N89 A;  1E42 A;  4ROE B;  1N3C A;  1YQK A;  1QN4 A;  1JFI C;  4B0A A;  1LWV A;  1FN7 A;  1C9B B;  1VTL E;  1QNE A;  1YTF A;  1QN3 A;  1NGM A;  1TGH A;  1N39 A;  1KO9 A;  1PZD A;  5IYD P;  1LWY A;  4PY5 A;  3SNS A;  1KYU A;  4TPS A;  1B9K A;  3HS8 A;  1YQL A;  3I0W A;  3RPJ A;  1M3H A;  1LWW A;  2D0A A;  2NOI A;  1VOL B;  2IV9 A;  2VJ0 A;  1KYD A;  1VOK A;  4I8O A;  1TBA B;  2IV8 A;  4WZS D;  3OC3 C;  2NOE A;  2FGT A;  1UT4 A;  2NOL A;  5AN4 A;  3OCI A;  4DUL A;  1VTO A;  3OST A;  1QNC A;  3ASM A;  3DPT A;  2LAE A;  4Q11 A;  2XHI A;  4ROC B;  2I5W A;  2NOH A;  2D0B A;  3HS9 A;  2HZS A;  2G30 A;  3F0Z A;  2JOI A;  4ROD B;  1QN5 A;  2Z8U A;  1R4X A;  1QNB A;  1QN8 A;  3IH7 A;  1NVP A;  1QNA A;  2NOB A;  3VN5 A;  5IYC P;  1QN6 A;  2MJ7 A;  3OSM A;  1YQR A;  2YH5 A;  1TBP A;  3H1Z A;  1KYF A;  1MP9 A;  3DPU A;  1HU0 A;  2MZ8 A;  3I0X A;  1KY6 A;  1QN7 A;  2O3O A;  1EBM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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