1JFIC

Crystal structure of the nc2-tbp-dna ternary complex
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
183
structure length
183
Chain Sequence
SHMSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords 5'-D(*TP*TP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*CP*
total genus 46
structure length 183
sequence length 183
ec nomenclature
pdb deposition date 2001-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00352 TBP Transcription factor TFIID (or TATA-binding protein, TBP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 1jfiC01
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 1jfiC02
2D0AA 4ROCB 3VN5A 1QNEA 3ASMA 1B9KA 1KYUA 1VTLE 1AISA 1VTOA 1NVPA 1QNBA 5IYBP 1PZDA 1KY7A 2D0CA 1QN5A 1QN7A 1NGMA 2G30A 3HS9A 4ROEB 1QN4A 1YTFA 4PY5A 1E42A 1KYFA 2D0BA 1PCZA 1W80A 2IV8A 1QN9A 1VOKA 1VOLB 4WZSD 1YTBA 1QN3A 5IYCP 2Z8UA 3EIKA 1QTPA 1CDWA 1MP9A 3HS8A 3OC3C 2MJ7A 4B0AA 5IYDP 1C9BB 1QTSA 1KY6A 2VJ0A 4RODB 1TBAB 1TGHA 3H1ZA 1JFIC 1QNCA 1QN6A 1KYDA 1RM1A 1TBPA 1NH2A 3OCIA 1QNAA 1D3UA 1R4XA 2IV9A 1QN8A
chains in the Genus database with same CATH superfamily
2DKAA 1QNBA 2H5AX 2JOIA 4C7PA 3TDHA 1TUOA 1HU0A 1N39A 4CFFA 2FKFA 2QLVA 3ASMA 3OH9A 4EAGA 1PCJX 1J3MA 2F7LA 1QN5A 5AN4A 3ENCA 1VKLA 1PZDA 1KY7A 3RSMA 5IYBP 3OH6A 1C47A 2LAEA 5JN5A 2G30A 3IH7A 3CWSA 2FKMX 1KO9A 1K2YX 1W80A 3D4VA 3N89A 2Z8UA 1UT4A 3EIKA 1CDWA 1MP9A 1PCMX 2HL9A 3OC3C 5IYDP 2QREA 1WJWA 2NLVA 2FGTA 1KY6A 3I3WA 3OGDA 1FN7A 2NOBA 3BKQX 2Y8LA 1QNCA 1KFIA 1KYDA 1LWVA 4IL8A 1R4XA 2EHBD 1QN8A 4D7RA 2D0AA 3VN5A 2O3OA 3D7QA 3DPUA 1YQMA 4DULA 1M5Q1 4EJZA 3RPJA 5F9CA 1N3CA 1AISA 1VTOA 3CWAA 2D0CA 1Q9UA 2HZSA 2QRDA 3F0ZA 3I0WA 1YTFA 4PY5A 2DKCA 1V5SA 1QN9A 3ULXA 2H4LX 1KFQA 1DIZA 1YTBA 1LWYA 4QG5A 3HS8A 4EJYA 3DPTA 1QTSA 2VJ0A 2R5XA 2YH5A 1UT7A 4MRQA 5BMNA 2HKPA 3H1ZA 4EAKA 2I5WA 2MZ8A 1QNAA 1XSZA 1TBPA 3EAYA 3ENOC 3OCIA 1MPGA 1M3QA 3OSTA 5KL0A 2V9JA 2IV9A 1JDYA 3PDKA 4I8OA 4TPSA 3TE5A 2Z0FA 4Q11A 2QRCA 3KTUA 1QNEA 2ZFDB 3I0XA 4HJHA 1B9KA 4EAIA 1LWWA 1M3HA 1C4GA 1T6AA 3CWUA 5HSHA 1NGMA 1UL7A 1P5DX 1QN4A 3UW2A 2JHJA 2PWWA 3OSEA 1PCZA 1VOLB 4WZSD 2NOEA 1QN3A 5IYCP 3CW7A 3F10A 4EAJA 3C04A 1P5GX 3KRMA 4B0AA 2Y8QA 2OOXA 1C9BB 1EBMA 2NOIA 1JFIC 2FUVA 1NH2A 1RM1A 1QN6A 1EUVA 2NOHA 2NOZA 1LXTA 2XHIA 4BJUA 4ROCB 2NOLA 1WQAA 2NVMA 2DKDA 4EALA 3NA5A 3SNSA 4WXAA 2V8QA 1KYUA 1VTLE 1NVPA 1QN7A 3CVTA 1N3AA 3HS9A 2QR1A 4ROEB 1E42A 1KYFA 2D0BA 2HZMA 2IV8A 1VOKA 2YA3A 1YQLA 2JHNA 3OLPA 5BMPA 1YQRA 5JMVD 2V92A 1QTPA 2NOFA 2MJ7A 3OSMA 4WX8A 1YQKA 2JPIA 1K35A 1PVSA 4RODB 5EPCA 2OOYA 1TBAB 3CVSA 1TGHA 4D7QA 3CWTA 1D3UA 3PMGA 3T4NA 2NWVA 2HL8A
chains in the Genus database with same CATH topology
2JOIA 1HU0A 1N39A 3ASMA 1QN5A 5AN4A 1QNBA 5IYBP 1PZDA 1KY7A 2LAEA 3IH7A 2G30A 1KO9A 1W80A 3N89A 2Z8UA 1UT4A 3EIKA 1CDWA 1MP9A 3OC3C 5IYDP 2NOBA 2FGTA 1KY6A 1FN7A 1QNCA 1KYDA 1LWVA 1R4XA 1QN8A 2D0AA 3VN5A 2O3OA 3DPUA 1YQMA 4DULA 4EJZA 3RPJA 1N3CA 1AISA 1VTOA 2D0CA 2HZSA 3I0WA 3F0ZA 1YTFA 4PY5A 1QN9A 3ULXA 1YTBA 1LWYA 3HS8A 4EJYA 3DPTA 1QTSA 2VJ0A 2YH5A 1UT7A 3H1ZA 2I5WA 2MZ8A 1QNAA 1TBPA 3OCIA 1M3QA 3OSTA 2IV9A 4I8OA 4TPSA 4Q11A 3KTUA 1QNEA 3I0XA 1B9KA 1LWWA 1M3HA 1NGMA 1QN4A 1PCZA 1VOLB 4WZSD 2NOEA 1QN3A 5IYCP 3F10A 3KRMA 4B0AA 1C9BB 1EBMA 2NOIA 1JFIC 1QN6A 1NH2A 1RM1A 2NOHA 2NOZA 2XHIA 4ROCB 2NOLA 3SNSA 1KYUA 1VTLE 1NVPA 1QN7A 1N3AA 3HS9A 4ROEB 1E42A 1KYFA 2D0BA 2HZMA 2IV8A 1VOKA 1YQLA 1YQRA 1QTPA 2NOFA 2MJ7A 3OSMA 1YQKA 4RODB 1TBAB 1TGHA 1D3UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2D0A A;  4ROC B;  3VN5 A;  1QNE A;  3ASM A;  1B9K A;  1KYU A;  1VTL E;  1AIS A;  1VTO A;  1NVP A;  1QNB A;  5IYB P;  1PZD A;  1KY7 A;  2D0C A;  1QN5 A;  1QN7 A;  1NGM A;  2G30 A;  3HS9 A;  4ROE B;  1QN4 A;  1YTF A;  4PY5 A;  1E42 A;  1KYF A;  2D0B A;  1PCZ A;  1W80 A;  2IV8 A;  1QN9 A;  1VOK A;  1VOL B;  4WZS D;  1YTB A;  1QN3 A;  5IYC P;  2Z8U A;  3EIK A;  1QTP A;  1CDW A;  1MP9 A;  3HS8 A;  3OC3 C;  2MJ7 A;  4B0A A;  5IYD P;  1C9B B;  1QTS A;  1KY6 A;  2VJ0 A;  4ROD B;  1TBA B;  1TGH A;  3H1Z A;  1JFI C;  1QNC A;  1QN6 A;  1KYD A;  1RM1 A;  1TBP A;  1NH2 A;  3OCI A;  1QNA A;  1D3U A;  1R4X A;  2IV9 A;  1QN8 A; 
#chains in the Genus database with same CATH topology
 2DKA A;  1QNB A;  2H5A X;  2JOI A;  4C7P A;  3TDH A;  1TUO A;  1HU0 A;  1N39 A;  4CFF A;  2FKF A;  2QLV A;  3ASM A;  3OH9 A;  4EAG A;  1PCJ X;  1J3M A;  2F7L A;  1QN5 A;  5AN4 A;  3ENC A;  1VKL A;  1PZD A;  1KY7 A;  3RSM A;  5IYB P;  3OH6 A;  1C47 A;  2LAE A;  5JN5 A;  2G30 A;  3IH7 A;  3CWS A;  2FKM X;  1KO9 A;  1K2Y X;  1W80 A;  3D4V A;  3N89 A;  2Z8U A;  1UT4 A;  3EIK A;  1CDW A;  1MP9 A;  1PCM X;  2HL9 A;  3OC3 C;  5IYD P;  2QRE A;  1WJW A;  2NLV A;  2FGT A;  1KY6 A;  3I3W A;  3OGD A;  1FN7 A;  2NOB A;  3BKQ X;  2Y8L A;  1QNC A;  1KFI A;  1KYD A;  1LWV A;  4IL8 A;  1R4X A;  2EHB D;  1QN8 A;  4D7R A;  2D0A A;  3VN5 A;  2O3O A;  3D7Q A;  3DPU A;  1YQM A;  4DUL A;  1M5Q 1;  4EJZ A;  3RPJ A;  5F9C A;  1N3C A;  1AIS A;  1VTO A;  3CWA A;  2D0C A;  1Q9U A;  2HZS A;  2QRD A;  3F0Z A;  3I0W A;  1YTF A;  4PY5 A;  2DKC A;  1V5S A;  1QN9 A;  3ULX A;  2H4L X;  1KFQ A;  1DIZ A;  1YTB A;  1LWY A;  4QG5 A;  3HS8 A;  4EJY A;  3DPT A;  1QTS A;  2VJ0 A;  2R5X A;  2YH5 A;  1UT7 A;  4MRQ A;  5BMN A;  2HKP A;  3H1Z A;  4EAK A;  2I5W A;  2MZ8 A;  1QNA A;  1XSZ A;  1TBP A;  3EAY A;  3ENO C;  3OCI A;  1MPG A;  1M3Q A;  3OST A;  5KL0 A;  2V9J A;  2IV9 A;  1JDY A;  3PDK A;  4I8O A;  4TPS A;  3TE5 A;  2Z0F A;  4Q11 A;  2QRC A;  3KTU A;  1QNE A;  2ZFD B;  3I0X A;  4HJH A;  1B9K A;  4EAI A;  1LWW A;  1M3H A;  1C4G A;  1T6A A;  3CWU A;  5HSH A;  1NGM A;  1UL7 A;  1P5D X;  1QN4 A;  3UW2 A;  2JHJ A;  2PWW A;  3OSE A;  1PCZ A;  1VOL B;  4WZS D;  2NOE A;  1QN3 A;  5IYC P;  3CW7 A;  3F10 A;  4EAJ A;  3C04 A;  1P5G X;  3KRM A;  4B0A A;  2Y8Q A;  2OOX A;  1C9B B;  1EBM A;  2NOI A;  1JFI C;  2FUV A;  1NH2 A;  1RM1 A;  1QN6 A;  1EUV A;  2NOH A;  2NOZ A;  1LXT A;  2XHI A;  4BJU A;  4ROC B;  2NOL A;  1WQA A;  2NVM A;  2DKD A;  4EAL A;  3NA5 A;  3SNS A;  4WXA A;  2V8Q A;  1KYU A;  1VTL E;  1NVP A;  1QN7 A;  3CVT A;  1N3A A;  3HS9 A;  2QR1 A;  4ROE B;  1E42 A;  1KYF A;  2D0B A;  2HZM A;  2IV8 A;  1VOK A;  2YA3 A;  1YQL A;  2JHN A;  3OLP A;  5BMP A;  1YQR A;  5JMV D;  2V92 A;  1QTP A;  2NOF A;  2MJ7 A;  3OSM A;  4WX8 A;  1YQK A;  2JPI A;  1K35 A;  1PVS A;  4ROD B;  5EPC A;  2OOY A;  1TBA B;  3CVS A;  1TGH A;  4D7Q A;  3CWT A;  1D3U A;  3PMG A;  3T4N A;  2NWV A;  2HL8 A; 
#chains in the Genus database with same CATH homology
 2JOI A;  1HU0 A;  1N39 A;  3ASM A;  1QN5 A;  5AN4 A;  1QNB A;  5IYB P;  1PZD A;  1KY7 A;  2LAE A;  3IH7 A;  2G30 A;  1KO9 A;  1W80 A;  3N89 A;  2Z8U A;  1UT4 A;  3EIK A;  1CDW A;  1MP9 A;  3OC3 C;  5IYD P;  2NOB A;  2FGT A;  1KY6 A;  1FN7 A;  1QNC A;  1KYD A;  1LWV A;  1R4X A;  1QN8 A;  2D0A A;  3VN5 A;  2O3O A;  3DPU A;  1YQM A;  4DUL A;  4EJZ A;  3RPJ A;  1N3C A;  1AIS A;  1VTO A;  2D0C A;  2HZS A;  3I0W A;  3F0Z A;  1YTF A;  4PY5 A;  1QN9 A;  3ULX A;  1YTB A;  1LWY A;  3HS8 A;  4EJY A;  3DPT A;  1QTS A;  2VJ0 A;  2YH5 A;  1UT7 A;  3H1Z A;  2I5W A;  2MZ8 A;  1QNA A;  1TBP A;  3OCI A;  1M3Q A;  3OST A;  2IV9 A;  4I8O A;  4TPS A;  4Q11 A;  3KTU A;  1QNE A;  3I0X A;  1B9K A;  1LWW A;  1M3H A;  1NGM A;  1QN4 A;  1PCZ A;  1VOL B;  4WZS D;  2NOE A;  1QN3 A;  5IYC P;  3F10 A;  3KRM A;  4B0A A;  1C9B B;  1EBM A;  2NOI A;  1JFI C;  1QN6 A;  1NH2 A;  1RM1 A;  2NOH A;  2NOZ A;  2XHI A;  4ROC B;  2NOL A;  3SNS A;  1KYU A;  1VTL E;  1NVP A;  1QN7 A;  1N3A A;  3HS9 A;  4ROE B;  1E42 A;  1KYF A;  2D0B A;  2HZM A;  2IV8 A;  1VOK A;  1YQL A;  1YQR A;  1QTP A;  2NOF A;  2MJ7 A;  3OSM A;  1YQK A;  4ROD B;  1TBA B;  1TGH A;  1D3U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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