1JFIC

Crystal structure of the nc2-tbp-dna ternary complex
Total Genus 46

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
183
structure length
183
Chain Sequence
SHMSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKT

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transcription/dna
source organism Homo sapiens
publication title Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex.
pubmed doi rcsb
molecule keywords 5'-D(*TP*TP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*CP*
total genus 46
structure length 183
sequence length 183
ec nomenclature
pdb deposition date 2001-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00352 TBP Transcription factor TFIID (or TATA-binding protein, TBP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 1jfiC01
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 1jfiC02
2MJ7A 1QN4A 1JFIC 4RODB 4B0AA 1KYFA 3HS8A 1QNBA 1QTSA 1CDWA 1QTPA 1QN7A 1YTBA 5IYDP 1NVPA 2Z8UA 1VOKA 1TBAB 1QNAA 1QNCA 1PCZA 4ROCB 1KYDA 2D0CA 3ASMA 4PY5A 1R4XA 1RM1A 1QN3A 3EIKA 1W80A 5IYCP 3H1ZA 2VJ0A 2D0AA 1QN9A 1TGHA 4WZSD 3OCIA 1YTFA 1TBPA 3HS9A 1E42A 1KY7A 1QN6A 1MP9A 3OC3C 4ROEB 1PZDA 1VTOA 1QN8A 1KYUA 1C9BB 3VN5A 1D3UA 1VOLB 2IV9A 1NGMA 1QN5A 1AISA 1NH2A 1KY6A 1QNEA 1B9KA 2D0BA 2G30A 1VTLE 5IYBP 2IV8A
chains in the Genus database with same CATH superfamily
3I0XA 3KRMA 1JFIC 1FN7A 1QN4A 4B0AA 1QNBA 3HS8A 2V9JA 2QRDA 3OSEA 1C47A 2Z0FA 1YQRA 1MPGA 2V92A 5BMPA 1EBMA 1KO9A 3D7QA 1J3MA 4D7QA 4EJZA 1N39A 4EAGA 3EIKA 3RSMA 5IYCP 2D0AA 1PCMX 2HL8A 1TGHA 4WZSD 4IL8A 1TBPA 3HS9A 1KY7A 1QN6A 1PZDA 1PVSA 1P5GX 3VN5A 2EHBD 1M3HA 3DPUA 2YH5A 4Q11A 3F10A 4EALA 1P5DX 1UT4A 1WJWA 3TDHA 5F9CA 1B9KA 2H4LX 2NVMA 2ZFDB 4WXAA 4BJUA 1VTLE 1HU0A 3OLPA 3NA5A 2IV8A 1TUOA 2YA3A 2QR1A 2HL9A 3N89A 3D4VA 1KYFA 1YTBA 2JHNA 1QTPA 1K2YX 1XSZA 3OH6A 3CWAA 5BMNA 1M5Q1 2Z8UA 3UW2A 1TBAB 2OOXA 1QNAA 2QLVA 1KYDA 1V5SA 1YQMA 5KL0A 4D7RA 2DKCA 2R5XA 3BKQX 1QN9A 1KFQA 1YTFA 1E42A 5HSHA 5EPCA 3ENOC 1EUVA 1C9BB 1YQKA 3KTUA 2IV9A 1QN5A 1DIZA 3EAYA 4MRQA 2FKFA 1NH2A 1KY6A 2FKMX 2NWVA 3OSTA 4QG5A 4EJYA 3PMGA 2NOIA 2NLVA 2PWWA 5IYBP 1M3QA 2JHJA 3CWTA 1LWWA 3SNSA 1Q9UA 2Y8QA 1QTSA 1QN7A 2JPIA 2JOIA 2NOFA 1KFIA 5IYDP 2QRCA 1JDYA 3CVSA 1NVPA 1VOKA 1QNCA 3PDKA 1PCZA 2FGTA 2OOYA 1UL7A 4PY5A 2V8QA 2FUVA 1R4XA 2MZ8A 4TPSA 1RM1A 1QN3A 1W80A 3F0ZA 4HJHA 2DKDA 3CWSA 3OCIA 3OC3C 1QN8A 2DKAA 1VTOA 1KYUA 4EAIA 2NOLA 3CWUA 1D3UA 1LXTA 1VKLA 2HZMA 1NGMA 3RPJA 1AISA 1QNEA 2G30A 3OSMA 5AN4A 2F7LA 2I5WA 3DPTA 3ULXA 3C04A 2LAEA 2MJ7A 2QREA 2NOBA 4RODB 1CDWA 2XHIA 4EAKA 4WX8A 1UT7A 3TE5A 4ROCB 1YQLA 2D0CA 2H5AX 3ASMA 3T4NA 4EAJA 1WQAA 3I3WA 2O3OA 2NOZA 3H1ZA 2VJ0A 1LWVA 3ENCA 1N3CA 1K35A 1MP9A 4I8OA 4CFFA 4ROEB 3I0WA 3CVTA 2NOHA 2NOEA 3IH7A 2Y8LA 3OH9A 1VOLB 5JMVD 4C7PA 2HKPA 1C4GA 2D0BA 1PCJX 4DULA 2HZSA 1LWYA 3CW7A 1N3AA 3OGDA 1T6AA 5JN5A
chains in the Genus database with same CATH topology
3I0XA 3KRMA 1JFIC 1FN7A 1QN4A 4B0AA 1QNBA 3HS8A 1YQRA 1EBMA 1KO9A 4EJZA 1N39A 3EIKA 5IYCP 2D0AA 1TGHA 4WZSD 1TBPA 3HS9A 1KY7A 1QN6A 1PZDA 3VN5A 1M3HA 3DPUA 2YH5A 4Q11A 3F10A 1UT4A 1B9KA 1HU0A 1VTLE 2IV8A 3N89A 1KYFA 1YTBA 1QTPA 2Z8UA 1QNAA 1TBAB 1KYDA 1YQMA 1QN9A 1YTFA 1E42A 1C9BB 1YQKA 3KTUA 2IV9A 1QN5A 1NH2A 1KY6A 3OSTA 4EJYA 2NOIA 5IYBP 1M3QA 1LWWA 3SNSA 1QTSA 1QN7A 2NOFA 2JOIA 5IYDP 1NVPA 1VOKA 1QNCA 1PCZA 2FGTA 4PY5A 4TPSA 1R4XA 2MZ8A 1RM1A 1QN3A 1W80A 3F0ZA 3OCIA 3OC3C 1QN8A 1VTOA 1KYUA 2NOLA 1D3UA 2HZMA 1NGMA 3RPJA 1AISA 1QNEA 2G30A 3OSMA 5AN4A 2I5WA 3DPTA 3ULXA 2LAEA 2MJ7A 2NOBA 4RODB 1CDWA 2XHIA 1UT7A 4ROCB 1YQLA 2D0CA 3ASMA 2O3OA 2NOZA 3H1ZA 2VJ0A 1LWVA 1N3CA 3I0WA 1MP9A 4I8OA 4ROEB 2NOHA 2NOEA 3IH7A 1VOLB 2D0BA 4DULA 2HZSA 1LWYA 1N3AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MJ7 A;  1QN4 A;  1JFI C;  4ROD B;  4B0A A;  1KYF A;  3HS8 A;  1QNB A;  1QTS A;  1CDW A;  1QTP A;  1QN7 A;  1YTB A;  5IYD P;  1NVP A;  2Z8U A;  1VOK A;  1TBA B;  1QNA A;  1QNC A;  1PCZ A;  4ROC B;  1KYD A;  2D0C A;  3ASM A;  4PY5 A;  1R4X A;  1RM1 A;  1QN3 A;  3EIK A;  1W80 A;  5IYC P;  3H1Z A;  2VJ0 A;  2D0A A;  1QN9 A;  1TGH A;  4WZS D;  3OCI A;  1YTF A;  1TBP A;  3HS9 A;  1E42 A;  1KY7 A;  1QN6 A;  1MP9 A;  3OC3 C;  4ROE B;  1PZD A;  1VTO A;  1QN8 A;  1KYU A;  1C9B B;  3VN5 A;  1D3U A;  1VOL B;  2IV9 A;  1NGM A;  1QN5 A;  1AIS A;  1NH2 A;  1KY6 A;  1QNE A;  1B9K A;  2D0B A;  2G30 A;  1VTL E;  5IYB P;  2IV8 A; 
#chains in the Genus database with same CATH topology
 3I0X A;  3KRM A;  1JFI C;  1FN7 A;  1QN4 A;  4B0A A;  1QNB A;  3HS8 A;  2V9J A;  2QRD A;  3OSE A;  1C47 A;  2Z0F A;  1YQR A;  1MPG A;  2V92 A;  5BMP A;  1EBM A;  1KO9 A;  3D7Q A;  1J3M A;  4D7Q A;  4EJZ A;  1N39 A;  4EAG A;  3EIK A;  3RSM A;  5IYC P;  2D0A A;  1PCM X;  2HL8 A;  1TGH A;  4WZS D;  4IL8 A;  1TBP A;  3HS9 A;  1KY7 A;  1QN6 A;  1PZD A;  1PVS A;  1P5G X;  3VN5 A;  2EHB D;  1M3H A;  3DPU A;  2YH5 A;  4Q11 A;  3F10 A;  4EAL A;  1P5D X;  1UT4 A;  1WJW A;  3TDH A;  5F9C A;  1B9K A;  2H4L X;  2NVM A;  2ZFD B;  4WXA A;  4BJU A;  1VTL E;  1HU0 A;  3OLP A;  3NA5 A;  2IV8 A;  1TUO A;  2YA3 A;  2QR1 A;  2HL9 A;  3N89 A;  3D4V A;  1KYF A;  1YTB A;  2JHN A;  1QTP A;  1K2Y X;  1XSZ A;  3OH6 A;  3CWA A;  5BMN A;  1M5Q 1;  2Z8U A;  3UW2 A;  1TBA B;  2OOX A;  1QNA A;  2QLV A;  1KYD A;  1V5S A;  1YQM A;  5KL0 A;  4D7R A;  2DKC A;  2R5X A;  3BKQ X;  1QN9 A;  1KFQ A;  1YTF A;  1E42 A;  5HSH A;  5EPC A;  3ENO C;  1EUV A;  1C9B B;  1YQK A;  3KTU A;  2IV9 A;  1QN5 A;  1DIZ A;  3EAY A;  4MRQ A;  2FKF A;  1NH2 A;  1KY6 A;  2FKM X;  2NWV A;  3OST A;  4QG5 A;  4EJY A;  3PMG A;  2NOI A;  2NLV A;  2PWW A;  5IYB P;  1M3Q A;  2JHJ A;  3CWT A;  1LWW A;  3SNS A;  1Q9U A;  2Y8Q A;  1QTS A;  1QN7 A;  2JPI A;  2JOI A;  2NOF A;  1KFI A;  5IYD P;  2QRC A;  1JDY A;  3CVS A;  1NVP A;  1VOK A;  1QNC A;  3PDK A;  1PCZ A;  2FGT A;  2OOY A;  1UL7 A;  4PY5 A;  2V8Q A;  2FUV A;  1R4X A;  2MZ8 A;  4TPS A;  1RM1 A;  1QN3 A;  1W80 A;  3F0Z A;  4HJH A;  2DKD A;  3CWS A;  3OCI A;  3OC3 C;  1QN8 A;  2DKA A;  1VTO A;  1KYU A;  4EAI A;  2NOL A;  3CWU A;  1D3U A;  1LXT A;  1VKL A;  2HZM A;  1NGM A;  3RPJ A;  1AIS A;  1QNE A;  2G30 A;  3OSM A;  5AN4 A;  2F7L A;  2I5W A;  3DPT A;  3ULX A;  3C04 A;  2LAE A;  2MJ7 A;  2QRE A;  2NOB A;  4ROD B;  1CDW A;  2XHI A;  4EAK A;  4WX8 A;  1UT7 A;  3TE5 A;  4ROC B;  1YQL A;  2D0C A;  2H5A X;  3ASM A;  3T4N A;  4EAJ A;  1WQA A;  3I3W A;  2O3O A;  2NOZ A;  3H1Z A;  2VJ0 A;  1LWV A;  3ENC A;  1N3C A;  1K35 A;  1MP9 A;  4I8O A;  4CFF A;  4ROE B;  3I0W A;  3CVT A;  2NOH A;  2NOE A;  3IH7 A;  2Y8L A;  3OH9 A;  1VOL B;  5JMV D;  4C7P A;  2HKP A;  1C4G A;  2D0B A;  1PCJ X;  4DUL A;  2HZS A;  1LWY A;  3CW7 A;  1N3A A;  3OGD A;  1T6A A;  5JN5 A; 
#chains in the Genus database with same CATH homology
 3I0X A;  3KRM A;  1JFI C;  1FN7 A;  1QN4 A;  4B0A A;  1QNB A;  3HS8 A;  1YQR A;  1EBM A;  1KO9 A;  4EJZ A;  1N39 A;  3EIK A;  5IYC P;  2D0A A;  1TGH A;  4WZS D;  1TBP A;  3HS9 A;  1KY7 A;  1QN6 A;  1PZD A;  3VN5 A;  1M3H A;  3DPU A;  2YH5 A;  4Q11 A;  3F10 A;  1UT4 A;  1B9K A;  1HU0 A;  1VTL E;  2IV8 A;  3N89 A;  1KYF A;  1YTB A;  1QTP A;  2Z8U A;  1QNA A;  1TBA B;  1KYD A;  1YQM A;  1QN9 A;  1YTF A;  1E42 A;  1C9B B;  1YQK A;  3KTU A;  2IV9 A;  1QN5 A;  1NH2 A;  1KY6 A;  3OST A;  4EJY A;  2NOI A;  5IYB P;  1M3Q A;  1LWW A;  3SNS A;  1QTS A;  1QN7 A;  2NOF A;  2JOI A;  5IYD P;  1NVP A;  1VOK A;  1QNC A;  1PCZ A;  2FGT A;  4PY5 A;  4TPS A;  1R4X A;  2MZ8 A;  1RM1 A;  1QN3 A;  1W80 A;  3F0Z A;  3OCI A;  3OC3 C;  1QN8 A;  1VTO A;  1KYU A;  2NOL A;  1D3U A;  2HZM A;  1NGM A;  3RPJ A;  1AIS A;  1QNE A;  2G30 A;  3OSM A;  5AN4 A;  2I5W A;  3DPT A;  3ULX A;  2LAE A;  2MJ7 A;  2NOB A;  4ROD B;  1CDW A;  2XHI A;  1UT7 A;  4ROC B;  1YQL A;  2D0C A;  3ASM A;  2O3O A;  2NOZ A;  3H1Z A;  2VJ0 A;  1LWV A;  1N3C A;  3I0W A;  1MP9 A;  4I8O A;  4ROE B;  2NOH A;  2NOE A;  3IH7 A;  1VOL B;  2D0B A;  4DUL A;  2HZS A;  1LWY A;  1N3A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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