1TGHA

Tata binding protein (tbp)/dna complex
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
180
structure length
180
Chain Sequence
SGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title How proteins recognize the TATA box.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords DNA (5'-D(*CP*GP*TP*AP*TP*AP*TP*AP*TP*AP*CP*G)-3')
total genus 46
structure length 180
sequence length 180
ec nomenclature
pdb deposition date 1996-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00352 TBP Transcription factor TFIID (or TATA-binding protein, TBP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 1tghA01
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 1tghA02
1KYFA 1D3UA 4ROCB 1C9BB 1E42A 1NVPA 1QN8A 1VOKA 3HS8A 2IV9A 3HS9A 1QN7A 3EIKA 1PCZA 1QN4A 3OCIA 4PY5A 3ASMA 1QTPA 1QTSA 1KY7A 2VJ0A 1NH2A 3H1ZA 1TBAB 1QNBA 1QN6A 1AISA 1QN5A 1VTOA 2IV8A 1QNEA 2D0AA 1KYDA 2MJ7A 5IYBP 1RM1A 4ROEB 1JFIC 1TGHA 5IYDP 4RODB 2G30A 1PZDA 3OC3C 1KYUA 1YTBA 1VOLB 3VN5A 1NGMA 4B0AA 5IYCP 4WZSD 1VTLE 1TBPA 1MP9A 2D0BA 2Z8UA 1QNCA 1QN3A 2D0CA 1QN9A 1YTFA 1R4XA 1W80A 1QNAA 1B9KA 1KY6A 1CDWA
chains in the Genus database with same CATH superfamily
1KYFA 2QRDA 1DIZA 1N3CA 1C9BB 1NVPA 2Y8QA 1UL7A 2R5XA 1UT4A 4PY5A 3ASMA 3OH6A 2JOIA 4C7PA 4EAJA 1QNBA 3OSEA 2V92A 2D0AA 1KYDA 2MJ7A 5IYBP 1VKLA 2I5WA 5IYDP 4I8OA 4EAGA 4TPSA 1TGHA 1M3QA 3I0WA 2G30A 2O3OA 1KYUA 2OOXA 3EAYA 3OSMA 1T6AA 5BMNA 5JMVD 1VOLB 1V5SA 2QRCA 3OGDA 5IYCP 3CVTA 2NOBA 1MPGA 2D0BA 3ULXA 2D0CA 5KL0A 3C04A 1QN9A 4DULA 1R4XA 1W80A 1KFIA 1QNAA 2NOEA 1B9KA 1C47A 4ROCB 2QR1A 2HZMA 5BMPA 1QN8A 1PVSA 3HS8A 2IV9A 3EIKA 1M5Q1 3TE5A 4MRQA 1XSZA 3CWAA 1QTSA 1QTPA 3OSTA 2NOFA 1NH2A 2JHJA 3T4NA 1LWWA 1QN6A 3CW7A 3UW2A 2YH5A 1J3MA 1PCMX 3CVSA 1FN7A 4EAIA 1WQAA 4IL8A 1TUOA 3OC3C 5F9CA 1Q9UA 2JHNA 1EBMA 1YTBA 3F0ZA 4B0AA 2Y8LA 4WZSD 1VTLE 1YQRA 1TBPA 1QNCA 2Z0FA 2DKCA 3CWSA 3PMGA 2H5AX 3CWUA 3N89A 4D7RA 1M3HA 2V9JA 1EUVA 2NWVA 1VOKA 4EJZA 2NOLA 1QN4A 3OH9A 4WX8A 1K2YX 5HSHA 1TBAB 3RSMA 1JDYA 1P5DX 1UT7A 3RPJA 1AISA 1VTOA 2IV8A 1QN5A 1LWVA 2FGTA 1LWYA 1PCJX 3SNSA 1RM1A 3CWTA 4EJYA 2NOHA 1PZDA 4QG5A 2XHIA 5AN4A 1C4GA 1HU0A 2NLVA 2V8QA 2H4LX 2NVMA 3DPUA 5EPCA 3TDHA 1NGMA 3OLPA 1YQKA 3D4VA 2FKFA 3KRMA 4CFFA 2LAEA 2NOIA 1YTFA 4EALA 2JPIA 2PWWA 3VN5A 3KTUA 1CDWA 4BJUA 4HJHA 1D3UA 1E42A 3NA5A 4EAKA 1YQMA 1QN7A 1P5GX 3HS9A 3PDKA 1PCZA 3D7QA 3OCIA 2DKAA 4Q11A 1N39A 2NOZA 3BKQX 3ENCA 2FUVA 1KY7A 1WJWA 2HZSA 1KFQA 2EHBD 1K35A 2HL9A 1KO9A 2F7LA 2VJ0A 3ENOC 3H1ZA 2YA3A 4WXAA 2MZ8A 1QNEA 2QREA 2QLVA 4D7QA 3I3WA 2HL8A 2OOYA 3IH7A 4ROEB 1JFIC 4RODB 2HKPA 1LXTA 3F10A 3I0XA 5JN5A 1N3AA 2ZFDB 1MP9A 2FKMX 2Z8UA 1YQLA 1QN3A 3DPTA 2DKDA 1KY6A
chains in the Genus database with same CATH topology
1KYFA 1N3CA 1C9BB 1NVPA 1UT4A 4PY5A 3ASMA 2JOIA 1QNBA 2D0AA 1KYDA 2MJ7A 5IYBP 2I5WA 5IYDP 4I8OA 1TGHA 4TPSA 1M3QA 3I0WA 2G30A 2O3OA 1KYUA 1VOLB 3OSMA 5IYCP 2NOBA 2D0BA 3ULXA 2D0CA 1QN9A 4DULA 1R4XA 1W80A 1QNAA 2NOEA 1B9KA 4ROCB 2HZMA 1QN8A 3HS8A 2IV9A 3EIKA 1QTPA 1QTSA 3OSTA 2NOFA 1NH2A 1LWWA 1QN6A 2YH5A 1FN7A 3OC3C 1EBMA 1YTBA 3F0ZA 4B0AA 4WZSD 1VTLE 1YQRA 1TBPA 1QNCA 3N89A 1M3HA 1VOKA 4EJZA 2NOLA 1QN4A 1TBAB 1UT7A 1AISA 3RPJA 1QN5A 1VTOA 2IV8A 1LWVA 2FGTA 1LWYA 3SNSA 1RM1A 4EJYA 2NOHA 1PZDA 2XHIA 5AN4A 1HU0A 3DPUA 1NGMA 1YQKA 3KRMA 2NOIA 2LAEA 1YTFA 3VN5A 3KTUA 1CDWA 1D3UA 1E42A 1YQMA 1QN7A 3HS9A 1PCZA 1N39A 3OCIA 2NOZA 4Q11A 1KY7A 2VJ0A 2HZSA 1KO9A 3H1ZA 2MZ8A 1QNEA 3IH7A 4ROEB 1JFIC 4RODB 3F10A 3I0XA 1N3AA 1MP9A 2Z8UA 1YQLA 1QN3A 3DPTA 1KY6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KYF A;  1D3U A;  4ROC B;  1C9B B;  1E42 A;  1NVP A;  1QN8 A;  1VOK A;  3HS8 A;  2IV9 A;  3HS9 A;  1QN7 A;  3EIK A;  1PCZ A;  1QN4 A;  3OCI A;  4PY5 A;  3ASM A;  1QTP A;  1QTS A;  1KY7 A;  2VJ0 A;  1NH2 A;  3H1Z A;  1TBA B;  1QNB A;  1QN6 A;  1AIS A;  1QN5 A;  1VTO A;  2IV8 A;  1QNE A;  2D0A A;  1KYD A;  2MJ7 A;  5IYB P;  1RM1 A;  4ROE B;  1JFI C;  1TGH A;  5IYD P;  4ROD B;  2G30 A;  1PZD A;  3OC3 C;  1KYU A;  1YTB A;  1VOL B;  3VN5 A;  1NGM A;  4B0A A;  5IYC P;  4WZS D;  1VTL E;  1TBP A;  1MP9 A;  2D0B A;  2Z8U A;  1QNC A;  1QN3 A;  2D0C A;  1QN9 A;  1YTF A;  1R4X A;  1W80 A;  1QNA A;  1B9K A;  1KY6 A;  1CDW A; 
#chains in the Genus database with same CATH topology
 1KYF A;  2QRD A;  1DIZ A;  1N3C A;  1C9B B;  1NVP A;  2Y8Q A;  1UL7 A;  2R5X A;  1UT4 A;  4PY5 A;  3ASM A;  3OH6 A;  2JOI A;  4C7P A;  4EAJ A;  1QNB A;  3OSE A;  2V92 A;  2D0A A;  1KYD A;  2MJ7 A;  5IYB P;  1VKL A;  2I5W A;  5IYD P;  4I8O A;  4EAG A;  4TPS A;  1TGH A;  1M3Q A;  3I0W A;  2G30 A;  2O3O A;  1KYU A;  2OOX A;  3EAY A;  3OSM A;  1T6A A;  5BMN A;  5JMV D;  1VOL B;  1V5S A;  2QRC A;  3OGD A;  5IYC P;  3CVT A;  2NOB A;  1MPG A;  2D0B A;  3ULX A;  2D0C A;  5KL0 A;  3C04 A;  1QN9 A;  4DUL A;  1R4X A;  1W80 A;  1KFI A;  1QNA A;  2NOE A;  1B9K A;  1C47 A;  4ROC B;  2QR1 A;  2HZM A;  5BMP A;  1QN8 A;  1PVS A;  3HS8 A;  2IV9 A;  3EIK A;  1M5Q 1;  3TE5 A;  4MRQ A;  1XSZ A;  3CWA A;  1QTS A;  1QTP A;  3OST A;  2NOF A;  1NH2 A;  2JHJ A;  3T4N A;  1LWW A;  1QN6 A;  3CW7 A;  3UW2 A;  2YH5 A;  1J3M A;  1PCM X;  3CVS A;  1FN7 A;  4EAI A;  1WQA A;  4IL8 A;  1TUO A;  3OC3 C;  5F9C A;  1Q9U A;  2JHN A;  1EBM A;  1YTB A;  3F0Z A;  4B0A A;  2Y8L A;  4WZS D;  1VTL E;  1YQR A;  1TBP A;  1QNC A;  2Z0F A;  2DKC A;  3CWS A;  3PMG A;  2H5A X;  3CWU A;  3N89 A;  4D7R A;  1M3H A;  2V9J A;  1EUV A;  2NWV A;  1VOK A;  4EJZ A;  2NOL A;  1QN4 A;  3OH9 A;  4WX8 A;  1K2Y X;  5HSH A;  1TBA B;  3RSM A;  1JDY A;  1P5D X;  1UT7 A;  3RPJ A;  1AIS A;  1VTO A;  2IV8 A;  1QN5 A;  1LWV A;  2FGT A;  1LWY A;  1PCJ X;  3SNS A;  1RM1 A;  3CWT A;  4EJY A;  2NOH A;  1PZD A;  4QG5 A;  2XHI A;  5AN4 A;  1C4G A;  1HU0 A;  2NLV A;  2V8Q A;  2H4L X;  2NVM A;  3DPU A;  5EPC A;  3TDH A;  1NGM A;  3OLP A;  1YQK A;  3D4V A;  2FKF A;  3KRM A;  4CFF A;  2LAE A;  2NOI A;  1YTF A;  4EAL A;  2JPI A;  2PWW A;  3VN5 A;  3KTU A;  1CDW A;  4BJU A;  4HJH A;  1D3U A;  1E42 A;  3NA5 A;  4EAK A;  1YQM A;  1QN7 A;  1P5G X;  3HS9 A;  3PDK A;  1PCZ A;  3D7Q A;  3OCI A;  2DKA A;  4Q11 A;  1N39 A;  2NOZ A;  3BKQ X;  3ENC A;  2FUV A;  1KY7 A;  1WJW A;  2HZS A;  1KFQ A;  2EHB D;  1K35 A;  2HL9 A;  1KO9 A;  2F7L A;  2VJ0 A;  3ENO C;  3H1Z A;  2YA3 A;  4WXA A;  2MZ8 A;  1QNE A;  2QRE A;  2QLV A;  4D7Q A;  3I3W A;  2HL8 A;  2OOY A;  3IH7 A;  4ROE B;  1JFI C;  4ROD B;  2HKP A;  1LXT A;  3F10 A;  3I0X A;  5JN5 A;  1N3A A;  2ZFD B;  1MP9 A;  2FKM X;  2Z8U A;  1YQL A;  1QN3 A;  3DPT A;  2DKD A;  1KY6 A; 
#chains in the Genus database with same CATH homology
 1KYF A;  1N3C A;  1C9B B;  1NVP A;  1UT4 A;  4PY5 A;  3ASM A;  2JOI A;  1QNB A;  2D0A A;  1KYD A;  2MJ7 A;  5IYB P;  2I5W A;  5IYD P;  4I8O A;  1TGH A;  4TPS A;  1M3Q A;  3I0W A;  2G30 A;  2O3O A;  1KYU A;  1VOL B;  3OSM A;  5IYC P;  2NOB A;  2D0B A;  3ULX A;  2D0C A;  1QN9 A;  4DUL A;  1R4X A;  1W80 A;  1QNA A;  2NOE A;  1B9K A;  4ROC B;  2HZM A;  1QN8 A;  3HS8 A;  2IV9 A;  3EIK A;  1QTP A;  1QTS A;  3OST A;  2NOF A;  1NH2 A;  1LWW A;  1QN6 A;  2YH5 A;  1FN7 A;  3OC3 C;  1EBM A;  1YTB A;  3F0Z A;  4B0A A;  4WZS D;  1VTL E;  1YQR A;  1TBP A;  1QNC A;  3N89 A;  1M3H A;  1VOK A;  4EJZ A;  2NOL A;  1QN4 A;  1TBA B;  1UT7 A;  1AIS A;  3RPJ A;  1QN5 A;  1VTO A;  2IV8 A;  1LWV A;  2FGT A;  1LWY A;  3SNS A;  1RM1 A;  4EJY A;  2NOH A;  1PZD A;  2XHI A;  5AN4 A;  1HU0 A;  3DPU A;  1NGM A;  1YQK A;  3KRM A;  2NOI A;  2LAE A;  1YTF A;  3VN5 A;  3KTU A;  1CDW A;  1D3U A;  1E42 A;  1YQM A;  1QN7 A;  3HS9 A;  1PCZ A;  1N39 A;  3OCI A;  2NOZ A;  4Q11 A;  1KY7 A;  2VJ0 A;  2HZS A;  1KO9 A;  3H1Z A;  2MZ8 A;  1QNE A;  3IH7 A;  4ROE B;  1JFI C;  4ROD B;  3F10 A;  3I0X A;  1N3A A;  1MP9 A;  2Z8U A;  1YQL A;  1QN3 A;  3DPT A;  1KY6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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