2QR1A

Crystal structure of the adenylate sensor from amp-activated protein kinase in complex with adp
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
126
structure length
116
Chain Sequence
KWHFGVRCRGDAPEILLAVYRALQRAGAQFTVPKPVNGKYRSDMYTIKSRWEIPHCKREGKNTYAYIELQLYEVMPGCFMLDVKSNGYKDIYSHDLKSSFPFLDLCAMLVCKLFSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
source organism Schizosaccharomyces pombe
publication title Structural Insight into AMPK Regulation: ADP Comes into Play.
pubmed doi rcsb
molecule keywords SNF1-like protein kinase ssp2
total genus 32
structure length 116
sequence length 126
chains with identical sequence C
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-07-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16579 AdenylateSensor Adenylate sensor of SNF1-like protein kinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2qr1A00
2Y8QA 2EHBD 4CFFA 2ZFDB 3TDHA 4EAKA 3T4NA 2OOXA 3OSEA 2QLVA 2V8QA 2YA3A 1V5SA 2QRCA 2QREA 2Y8LA 2OOYA 4EALA 1UL7A 2QRDA 2V9JA 2QR1A 4EAJA 2V92A 4EAGA 3TE5A 4EAIA
chains in the Genus database with same CATH superfamily
3CVSA 4PY5A 3I0XA 4CFFA 1QN3A 2FGTA 3OH9A 1C4GA 3BKQX 1T6AA 3OSEA 1PCZA 1TBAB 2V8QA 1WQAA 3RSMA 3KTUA 2QREA 2Z8UA 4B0AA 1PVSA 1NGMA 3F0ZA 1LWWA 1N3AA 5BMPA 3DPUA 1D3UA 2D0BA 2NOFA 4EALA 3OH6A 1LXTA 3D4VA 2HZMA 1NH2A 4MRQA 1UT7A 3UW2A 1JFIC 2IV8A 4WX8A 1KYDA 2HL8A 5EPCA 1KFIA 3SNSA 4D7RA 2NOZA 1Q9UA 3TE5A 2DKAA 1KY6A 3NA5A 1M3HA 1KYFA 2H5AX 1KO9A 2NVMA 1MPGA 1FN7A 2ZFDB 1MP9A 4EAKA 1LWYA 1VOKA 3T4NA 4WXAA 4WZSD 1VOLB 5JMVD 4IL8A 4ROCB 1NVPA 2MZ8A 2MJ7A 1VTOA 3OC3C 3DPTA 4D7QA 2D0CA 2DKCA 1P5GX 1N3CA 1DIZA 3ULXA 4DULA 1QN9A 2F7LA 1W80A 1TUOA 1C47A 1K35A 3EAYA 4ROEB 2QRDA 2V9JA 2FUVA 2QR1A 1R4XA 2R5XA 3CW7A 3N89A 4EAGA 3CVTA 3H1ZA 1QN7A 1KY7A 2JHNA 1UT4A 1RM1A 1TGHA 1QNAA 2HL9A 4Q11A 1JDYA 1QTPA 2NOEA 1N39A 3OSTA 2NOLA 3F10A 2XHIA 2FKMX 1J3MA 1YTFA 2HKPA 1EBMA 1EUVA 2NOBA 1M5Q1 1CDWA 1K2YX 3CWUA 1YQKA 1V5SA 2G30A 4I8OA 2QRCA 2JHJA 2I5WA 1C9BB 2JOIA 3RPJA 2Y8LA 2OOYA 3HS9A 3PMGA 3I0WA 5IYBP 1KYUA 5F9CA 2VJ0A 5HSHA 3IH7A 1YQLA 4EJZA 2NOHA 3PDKA 3VN5A 2O3OA 2D0AA 4QG5A 4EJYA 1QNBA 1VTLE 1AISA 3ASMA 1QN6A 3ENOC 2PWWA 4TPSA 1QNCA 1PCMX 3C04A 2NOIA 4EAIA 2HZSA 2Y8QA 2EHBD 3EIKA 1HU0A 2DKDA 1YTBA 5AN4A 1QN4A 3TDHA 2NWVA 3D7QA 1TBPA 5IYDP 3CWTA 1VKLA 1WJWA 2OOXA 3ENCA 3CWAA 2QLVA 3I3WA 1QNEA 2JPIA 4BJUA 2YA3A 1P5DX 4C7PA 3OLPA 1E42A 2H4LX 1PZDA 3OSMA 1QN5A 1KFQA 2NLVA 5IYCP 2FKFA 3HS8A 1YQMA 3CWSA 2IV9A 5BMNA 2YH5A 2Z0FA 4RODB 5JN5A 4HJHA 1QTSA 1UL7A 1YQRA 4EAJA 1PCJX 3OCIA 3OGDA 2V92A 1LWVA 1QN8A 3KRMA 1M3QA 2LAEA 1XSZA 5KL0A 1B9KA
chains in the Genus database with same CATH topology
2Y8QA 2EHBD 4CFFA 2ZFDB 3TDHA 4EAKA 3T4NA 2OOXA 3OSEA 2QLVA 2V8QA 2YA3A 1V5SA 2QRCA 2QREA 2Y8LA 2OOYA 4EALA 1UL7A 2QRDA 2V9JA 2QR1A 4EAJA 2V92A 4EAGA 3TE5A 4EAIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y8Q A;  2EHB D;  4CFF A;  2ZFD B;  3TDH A;  4EAK A;  3T4N A;  2OOX A;  3OSE A;  2QLV A;  2V8Q A;  2YA3 A;  1V5S A;  2QRC A;  2QRE A;  2Y8L A;  2OOY A;  4EAL A;  1UL7 A;  2QRD A;  2V9J A;  2QR1 A;  4EAJ A;  2V92 A;  4EAG A;  3TE5 A;  4EAI A; 
#chains in the Genus database with same CATH topology
 3CVS A;  4PY5 A;  3I0X A;  4CFF A;  1QN3 A;  2FGT A;  3OH9 A;  1C4G A;  3BKQ X;  1T6A A;  3OSE A;  1PCZ A;  1TBA B;  2V8Q A;  1WQA A;  3RSM A;  3KTU A;  2QRE A;  2Z8U A;  4B0A A;  1PVS A;  1NGM A;  3F0Z A;  1LWW A;  1N3A A;  5BMP A;  3DPU A;  1D3U A;  2D0B A;  2NOF A;  4EAL A;  3OH6 A;  1LXT A;  3D4V A;  2HZM A;  1NH2 A;  4MRQ A;  1UT7 A;  3UW2 A;  1JFI C;  2IV8 A;  4WX8 A;  1KYD A;  2HL8 A;  5EPC A;  1KFI A;  3SNS A;  4D7R A;  2NOZ A;  1Q9U A;  3TE5 A;  2DKA A;  1KY6 A;  3NA5 A;  1M3H A;  1KYF A;  2H5A X;  1KO9 A;  2NVM A;  1MPG A;  1FN7 A;  2ZFD B;  1MP9 A;  4EAK A;  1LWY A;  1VOK A;  3T4N A;  4WXA A;  4WZS D;  1VOL B;  5JMV D;  4IL8 A;  4ROC B;  1NVP A;  2MZ8 A;  2MJ7 A;  1VTO A;  3OC3 C;  3DPT A;  4D7Q A;  2D0C A;  2DKC A;  1P5G X;  1N3C A;  1DIZ A;  3ULX A;  4DUL A;  1QN9 A;  2F7L A;  1W80 A;  1TUO A;  1C47 A;  1K35 A;  3EAY A;  4ROE B;  2QRD A;  2V9J A;  2FUV A;  2QR1 A;  1R4X A;  2R5X A;  3CW7 A;  3N89 A;  4EAG A;  3CVT A;  3H1Z A;  1QN7 A;  1KY7 A;  2JHN A;  1UT4 A;  1RM1 A;  1TGH A;  1QNA A;  2HL9 A;  4Q11 A;  1JDY A;  1QTP A;  2NOE A;  1N39 A;  3OST A;  2NOL A;  3F10 A;  2XHI A;  2FKM X;  1J3M A;  1YTF A;  2HKP A;  1EBM A;  1EUV A;  2NOB A;  1M5Q 1;  1CDW A;  1K2Y X;  3CWU A;  1YQK A;  1V5S A;  2G30 A;  4I8O A;  2QRC A;  2JHJ A;  2I5W A;  1C9B B;  2JOI A;  3RPJ A;  2Y8L A;  2OOY A;  3HS9 A;  3PMG A;  3I0W A;  5IYB P;  1KYU A;  5F9C A;  2VJ0 A;  5HSH A;  3IH7 A;  1YQL A;  4EJZ A;  2NOH A;  3PDK A;  3VN5 A;  2O3O A;  2D0A A;  4QG5 A;  4EJY A;  1QNB A;  1VTL E;  1AIS A;  3ASM A;  1QN6 A;  3ENO C;  2PWW A;  4TPS A;  1QNC A;  1PCM X;  3C04 A;  2NOI A;  4EAI A;  2HZS A;  2Y8Q A;  2EHB D;  3EIK A;  1HU0 A;  2DKD A;  1YTB A;  5AN4 A;  1QN4 A;  3TDH A;  2NWV A;  3D7Q A;  1TBP A;  5IYD P;  3CWT A;  1VKL A;  1WJW A;  2OOX A;  3ENC A;  3CWA A;  2QLV A;  3I3W A;  1QNE A;  2JPI A;  4BJU A;  2YA3 A;  1P5D X;  4C7P A;  3OLP A;  1E42 A;  2H4L X;  1PZD A;  3OSM A;  1QN5 A;  1KFQ A;  2NLV A;  5IYC P;  2FKF A;  3HS8 A;  1YQM A;  3CWS A;  2IV9 A;  5BMN A;  2YH5 A;  2Z0F A;  4ROD B;  5JN5 A;  4HJH A;  1QTS A;  1UL7 A;  1YQR A;  4EAJ A;  1PCJ X;  3OCI A;  3OGD A;  2V92 A;  1LWV A;  1QN8 A;  3KRM A;  1M3Q A;  2LAE A;  1XSZ A;  5KL0 A;  1B9K A; 
#chains in the Genus database with same CATH homology
 2Y8Q A;  2EHB D;  4CFF A;  2ZFD B;  3TDH A;  4EAK A;  3T4N A;  2OOX A;  3OSE A;  2QLV A;  2V8Q A;  2YA3 A;  1V5S A;  2QRC A;  2QRE A;  2Y8L A;  2OOY A;  4EAL A;  1UL7 A;  2QRD A;  2V9J A;  2QR1 A;  4EAJ A;  2V92 A;  4EAG A;  3TE5 A;  4EAI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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