2QRCA

Crystal structure of the adenylate sensor from amp-activated protein kinase in complex with adp and amp
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
126
structure length
116
Chain Sequence
KWHFGVRCRGDAPEILLAVYRALQRAGAQFTVPKPVNGKYRSDMYTIKSRWEIPHCKREGKNTYAYIELQLYEVMPGCFMLDVKSNGYKDIYSHDLKSSFPFLDLCAMLVCKLFSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insight into AMPK Regulation: ADP Comes into Play.
pubmed doi rcsb
molecule tags Transferase
source organism Schizosaccharomyces pombe
molecule keywords SNF1-like protein kinase ssp2
total genus 32
structure length 116
sequence length 126
chains with identical sequence C
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16579 AdenylateSensor Adenylate sensor of SNF1-like protein kinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2qrcA00
2QR1A 4EAIA 2Y8QA 4EALA 2QLVA 2V92A 1UL7A 4CFFA 2ZFDB 4EAGA 2YA3A 3OSEA 4EAKA 3TE5A 3T4NA 2QRCA 2V8QA 4EAJA 2QRDA 2V9JA 1V5SA 3TDHA 2OOXA 2QREA 2OOYA 2EHBD 2Y8LA
chains in the Genus database with same CATH superfamily
4BJUA 1YQKA 1QN8A 1RM1A 1LWWA 4HJHA 1LXTA 4DULA 3NA5A 1PCJX 4CFFA 4MRQA 3OH9A 3EIKA 1B9KA 5F9CA 1VTLE 3ENCA 4RODB 1YTBA 4EJYA 4WXAA 2NOFA 3CW7A 1N3CA 4PY5A 3ULXA 2FKFA 4D7RA 1XSZA 1E42A 3D4VA 1J3MA 1CDWA 1AISA 3PDKA 1KO9A 4EAJA 1KY7A 3OSMA 1QNEA 5EPCA 2YH5A 2DKDA 2H5AX 1K35A 2IV9A 1N3AA 5JN5A 2JOIA 3KRMA 1DIZA 2D0AA 1VKLA 2JPIA 1QN3A 1MPGA 3OGDA 2H4LX 1WJWA 3RSMA 1NVPA 2FGTA 1WQAA 2F7LA 2HL9A 2QR1A 3HS8A 2Y8QA 3OC3C 1QN4A 1KYDA 1TBAB 3BKQX 3ENOC 1TBPA 1UL7A 1P5DX 4ROEB 2DKAA 2HL8A 3RPJA 2JHNA 1NH2A 1VOLB 4EAGA 2DKCA 2YA3A 1Q9UA 3I0WA 1JDYA 1KY6A 1QN7A 1TUOA 1PVSA 3N89A 3TE5A 3CWAA 1M3HA 2V8QA 4TPSA 4IL8A 1W80A 2QRDA 2PWWA 1QNBA 3CWTA 3TDHA 2OOXA 2HZSA 1PZDA 2VJ0A 1HU0A 1C47A 1UT7A 1QNCA 1EBMA 3PMGA 2Y8LA 4C7PA 3F0ZA 1YQLA 4EAIA 1JFIC 1TGHA 3CWUA 1KFQA 4B0AA 3CWSA 5HSHA 4EALA 5AN4A 1M5Q1 2HZMA 2XHIA 3D7QA 1NGMA 3OLPA 2ZFDB 3F10A 1YQMA 3UW2A 2Z8UA 1QN6A 1QN9A 2NOHA 1QTSA 3OSEA 2I5WA 2HKPA 2NOBA 1YQRA 1FN7A 3OSTA 1LWVA 4EAKA 3T4NA 1N39A 2R5XA 2QRCA 5JMVD 4Q11A 1PCZA 4EJZA 1KFIA 5IYCP 2V9JA 1V5SA 2NVMA 3IH7A 3CVSA 1QN5A 3C04A 2NOEA 2QREA 2FKMX 1EUVA 2G30A 1MP9A 1R4XA 2EHBD 5IYBP 2IV8A 2LAEA 4ROCB 1T6AA 3HS9A 3ASMA 3H1ZA 2MZ8A 2JHJA 3KTUA 2QLVA 2V92A 1UT4A 2Z0FA 5BMNA 1VTOA 1QNAA 2D0CA 4WX8A 1QTPA 3SNSA 3CVTA 3OH6A 2NWVA 1LWYA 1D3UA 1YTFA 1VOKA 2NOLA 1P5GX 2MJ7A 2NOZA 1M3QA 4D7QA 4WZSD 3I0XA 2NOIA 5BMPA 3EAYA 1KYFA 3DPUA 1KYUA 1PCMX 1C9BB 1K2YX 3VN5A 1C4GA 2D0BA 3I3WA 5IYDP 4QG5A 2OOYA 2FUVA 2O3OA 3OCIA 5KL0A 2NLVA 3DPTA 4I8OA
chains in the Genus database with same CATH topology
2QR1A 4EAIA 2Y8QA 4EALA 2QLVA 2V92A 1UL7A 4CFFA 2ZFDB 4EAGA 2YA3A 3OSEA 4EAKA 3TE5A 3T4NA 2QRCA 2V8QA 4EAJA 2QRDA 2V9JA 1V5SA 3TDHA 2OOXA 2QREA 2OOYA 2EHBD 2Y8LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QR1 A;  4EAI A;  2Y8Q A;  4EAL A;  2QLV A;  2V92 A;  1UL7 A;  4CFF A;  2ZFD B;  4EAG A;  2YA3 A;  3OSE A;  4EAK A;  3TE5 A;  3T4N A;  2QRC A;  2V8Q A;  4EAJ A;  2QRD A;  2V9J A;  1V5S A;  3TDH A;  2OOX A;  2QRE A;  2OOY A;  2EHB D;  2Y8L A; 
#chains in the Genus database with same CATH topology
 4BJU A;  1YQK A;  1QN8 A;  1RM1 A;  1LWW A;  4HJH A;  1LXT A;  4DUL A;  3NA5 A;  1PCJ X;  4CFF A;  4MRQ A;  3OH9 A;  3EIK A;  1B9K A;  5F9C A;  1VTL E;  3ENC A;  4ROD B;  1YTB A;  4EJY A;  4WXA A;  2NOF A;  3CW7 A;  1N3C A;  4PY5 A;  3ULX A;  2FKF A;  4D7R A;  1XSZ A;  1E42 A;  3D4V A;  1J3M A;  1CDW A;  1AIS A;  3PDK A;  1KO9 A;  4EAJ A;  1KY7 A;  3OSM A;  1QNE A;  5EPC A;  2YH5 A;  2DKD A;  2H5A X;  1K35 A;  2IV9 A;  1N3A A;  5JN5 A;  2JOI A;  3KRM A;  1DIZ A;  2D0A A;  1VKL A;  2JPI A;  1QN3 A;  1MPG A;  3OGD A;  2H4L X;  1WJW A;  3RSM A;  1NVP A;  2FGT A;  1WQA A;  2F7L A;  2HL9 A;  2QR1 A;  3HS8 A;  2Y8Q A;  3OC3 C;  1QN4 A;  1KYD A;  1TBA B;  3BKQ X;  3ENO C;  1TBP A;  1UL7 A;  1P5D X;  4ROE B;  2DKA A;  2HL8 A;  3RPJ A;  2JHN A;  1NH2 A;  1VOL B;  4EAG A;  2DKC A;  2YA3 A;  1Q9U A;  3I0W A;  1JDY A;  1KY6 A;  1QN7 A;  1TUO A;  1PVS A;  3N89 A;  3TE5 A;  3CWA A;  1M3H A;  2V8Q A;  4TPS A;  4IL8 A;  1W80 A;  2QRD A;  2PWW A;  1QNB A;  3CWT A;  3TDH A;  2OOX A;  2HZS A;  1PZD A;  2VJ0 A;  1HU0 A;  1C47 A;  1UT7 A;  1QNC A;  1EBM A;  3PMG A;  2Y8L A;  4C7P A;  3F0Z A;  1YQL A;  4EAI A;  1JFI C;  1TGH A;  3CWU A;  1KFQ A;  4B0A A;  3CWS A;  5HSH A;  4EAL A;  5AN4 A;  1M5Q 1;  2HZM A;  2XHI A;  3D7Q A;  1NGM A;  3OLP A;  2ZFD B;  3F10 A;  1YQM A;  3UW2 A;  2Z8U A;  1QN6 A;  1QN9 A;  2NOH A;  1QTS A;  3OSE A;  2I5W A;  2HKP A;  2NOB A;  1YQR A;  1FN7 A;  3OST A;  1LWV A;  4EAK A;  3T4N A;  1N39 A;  2R5X A;  2QRC A;  5JMV D;  4Q11 A;  1PCZ A;  4EJZ A;  1KFI A;  5IYC P;  2V9J A;  1V5S A;  2NVM A;  3IH7 A;  3CVS A;  1QN5 A;  3C04 A;  2NOE A;  2QRE A;  2FKM X;  1EUV A;  2G30 A;  1MP9 A;  1R4X A;  2EHB D;  5IYB P;  2IV8 A;  2LAE A;  4ROC B;  1T6A A;  3HS9 A;  3ASM A;  3H1Z A;  2MZ8 A;  2JHJ A;  3KTU A;  2QLV A;  2V92 A;  1UT4 A;  2Z0F A;  5BMN A;  1VTO A;  1QNA A;  2D0C A;  4WX8 A;  1QTP A;  3SNS A;  3CVT A;  3OH6 A;  2NWV A;  1LWY A;  1D3U A;  1YTF A;  1VOK A;  2NOL A;  1P5G X;  2MJ7 A;  2NOZ A;  1M3Q A;  4D7Q A;  4WZS D;  3I0X A;  2NOI A;  5BMP A;  3EAY A;  1KYF A;  3DPU A;  1KYU A;  1PCM X;  1C9B B;  1K2Y X;  3VN5 A;  1C4G A;  2D0B A;  3I3W A;  5IYD P;  4QG5 A;  2OOY A;  2FUV A;  2O3O A;  3OCI A;  5KL0 A;  2NLV A;  3DPT A;  4I8O A; 
#chains in the Genus database with same CATH homology
 2QR1 A;  4EAI A;  2Y8Q A;  4EAL A;  2QLV A;  2V92 A;  1UL7 A;  4CFF A;  2ZFD B;  4EAG A;  2YA3 A;  3OSE A;  4EAK A;  3TE5 A;  3T4N A;  2QRC A;  2V8Q A;  4EAJ A;  2QRD A;  2V9J A;  1V5S A;  3TDH A;  2OOX A;  2QRE A;  2OOY A;  2EHB D;  2Y8L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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