2QREA

Crystal structure of the adenylate sensor from amp-activated protein kinase in complex with 5-aminoimidazole-4-carboxamide 1-beta-d-ribofuranotide (zmp)
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
126
structure length
109
Chain Sequence
KWHFGVRCRGDAPEILLAVYRALQRAGAQFTVPKPVNSDMYTIKSRWEIPHCKREGKNTYAYIELQLYEVMPGCFMLDVKSNGYKDIYSKSSFPFLDLCAMLVCKLFSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insight into AMPK Regulation: ADP Comes into Play.
pubmed doi rcsb
molecule tags Transferase
source organism Schizosaccharomyces pombe
molecule keywords SNF1-like protein kinase ssp2
total genus 29
structure length 109
sequence length 126
chains with identical sequence C
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16579 AdenylateSensor Adenylate sensor of SNF1-like protein kinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2qreA00
3OSEA 3TDHA 4EAGA 2QR1A 1V5SA 3T4NA 2Y8LA 3TE5A 2YA3A 4EAIA 4EAJA 2EHBD 2OOXA 2QREA 2QLVA 4CFFA 2QRCA 2Y8QA 1UL7A 2V8QA 2V9JA 2ZFDB 2V92A 4EALA 4EAKA 2QRDA 2OOYA
chains in the Genus database with same CATH superfamily
1QTSA 5F9CA 4EAGA 1EBMA 4QG5A 1HU0A 4I8OA 1V5SA 3CVSA 1MPGA 2HL8A 2YH5A 5JMVD 1TGHA 2Z8UA 2Y8LA 1KFQA 3TE5A 1T6AA 2DKCA 2FKMX 3N89A 1N3CA 1QNEA 3CW7A 1M3HA 1W80A 2QLVA 1YTBA 2NOHA 3ENCA 1WJWA 1WQAA 2JPIA 3ASMA 1XSZA 3H1ZA 4CFFA 1C4GA 1R4XA 1PCJX 1QN8A 3CVTA 3F0ZA 1NVPA 1QNAA 1VKLA 3EIKA 1UT7A 4BJUA 2D0CA 1UL7A 1YQRA 2NOIA 4D7QA 1KYUA 2H4LX 3CWTA 2ZFDB 2NOLA 2V92A 4B0AA 1KY6A 2HKPA 3CWUA 2NOBA 2QRDA 3SNSA 5BMNA 1Q9UA 2OOYA 3VN5A 3OSEA 1DIZA 1PCZA 2QR1A 3OC3C 1LWWA 1QN3A 3NA5A 1TUOA 3I0XA 5JN5A 2YA3A 1QN7A 1PZDA 4EAJA 2OOXA 1JDYA 2NVMA 3OH9A 5BMPA 2NLVA 4MRQA 1VOKA 3OSTA 1KYDA 2FKFA 3OLPA 5HSHA 4D7RA 2V9JA 4EJZA 4IL8A 3HS9A 4WXAA 4DULA 1QNCA 1YQLA 2NWVA 1N3AA 2G30A 3D4VA 3F10A 3HS8A 1PVSA 3PMGA 3ULXA 4TPSA 1VTLE 1NGMA 1QTPA 1QN9A 1QN5A 1LWYA 1KO9A 3T4NA 2HL9A 3KTUA 1YTFA 3OCIA 1FN7A 2D0BA 3I3WA 1CDWA 2DKAA 2R5XA 4EAIA 5EPCA 2EHBD 3RPJA 2QREA 3OGDA 1VOLB 2HZMA 1E42A 1LWVA 2LAEA 3ENOC 4Q11A 1NH2A 2JHNA 1KYFA 2V8QA 3C04A 2O3OA 1MP9A 2NOFA 1B9KA 3CWSA 3DPUA 4ROCB 2JOIA 2PWWA 1P5GX 5IYDP 4EJYA 1JFIC 4RODB 2D0AA 1QNBA 4ROEB 3I0WA 3TDHA 1VTOA 5IYBP 1K2YX 1YQKA 4PY5A 2H5AX 4C7PA 1C47A 1TBPA 2HZSA 3PDKA 3IH7A 1C9BB 1QN6A 2NOEA 1P5DX 2XHIA 3BKQX 3OSMA 1KY7A 2FUVA 5AN4A 1D3UA 3RSMA 1N39A 2FGTA 2MJ7A 1AISA 2IV9A 1TBAB 2QRCA 2VJ0A 2Z0FA 3UW2A 1J3MA 4HJHA 5KL0A 1M5Q1 2I5WA 3EAYA 2Y8QA 3OH6A 1YQMA 2NOZA 2F7LA 2JHJA 1K35A 2IV8A 1QN4A 3CWAA 1PCMX 3DPTA 1UT4A 2DKDA 1LXTA 4WX8A 2MZ8A 1KFIA 4EALA 4WZSD 4EAKA 5IYCP 1RM1A 3D7QA 1EUVA 1M3QA 3KRMA
chains in the Genus database with same CATH topology
3OSEA 3TDHA 4EAGA 2QR1A 1V5SA 3T4NA 2Y8LA 3TE5A 2YA3A 4EAIA 4EAJA 2EHBD 2OOXA 2QREA 2QLVA 4CFFA 2QRCA 2Y8QA 1UL7A 2V8QA 2V9JA 2ZFDB 2V92A 4EALA 4EAKA 2QRDA 2OOYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OSE A;  3TDH A;  4EAG A;  2QR1 A;  1V5S A;  3T4N A;  2Y8L A;  3TE5 A;  2YA3 A;  4EAI A;  4EAJ A;  2EHB D;  2OOX A;  2QRE A;  2QLV A;  4CFF A;  2QRC A;  2Y8Q A;  1UL7 A;  2V8Q A;  2V9J A;  2ZFD B;  2V92 A;  4EAL A;  4EAK A;  2QRD A;  2OOY A; 
#chains in the Genus database with same CATH topology
 1QTS A;  5F9C A;  4EAG A;  1EBM A;  4QG5 A;  1HU0 A;  4I8O A;  1V5S A;  3CVS A;  1MPG A;  2HL8 A;  2YH5 A;  5JMV D;  1TGH A;  2Z8U A;  2Y8L A;  1KFQ A;  3TE5 A;  1T6A A;  2DKC A;  2FKM X;  3N89 A;  1N3C A;  1QNE A;  3CW7 A;  1M3H A;  1W80 A;  2QLV A;  1YTB A;  2NOH A;  3ENC A;  1WJW A;  1WQA A;  2JPI A;  3ASM A;  1XSZ A;  3H1Z A;  4CFF A;  1C4G A;  1R4X A;  1PCJ X;  1QN8 A;  3CVT A;  3F0Z A;  1NVP A;  1QNA A;  1VKL A;  3EIK A;  1UT7 A;  4BJU A;  2D0C A;  1UL7 A;  1YQR A;  2NOI A;  4D7Q A;  1KYU A;  2H4L X;  3CWT A;  2ZFD B;  2NOL A;  2V92 A;  4B0A A;  1KY6 A;  2HKP A;  3CWU A;  2NOB A;  2QRD A;  3SNS A;  5BMN A;  1Q9U A;  2OOY A;  3VN5 A;  3OSE A;  1DIZ A;  1PCZ A;  2QR1 A;  3OC3 C;  1LWW A;  1QN3 A;  3NA5 A;  1TUO A;  3I0X A;  5JN5 A;  2YA3 A;  1QN7 A;  1PZD A;  4EAJ A;  2OOX A;  1JDY A;  2NVM A;  3OH9 A;  5BMP A;  2NLV A;  4MRQ A;  1VOK A;  3OST A;  1KYD A;  2FKF A;  3OLP A;  5HSH A;  4D7R A;  2V9J A;  4EJZ A;  4IL8 A;  3HS9 A;  4WXA A;  4DUL A;  1QNC A;  1YQL A;  2NWV A;  1N3A A;  2G30 A;  3D4V A;  3F10 A;  3HS8 A;  1PVS A;  3PMG A;  3ULX A;  4TPS A;  1VTL E;  1NGM A;  1QTP A;  1QN9 A;  1QN5 A;  1LWY A;  1KO9 A;  3T4N A;  2HL9 A;  3KTU A;  1YTF A;  3OCI A;  1FN7 A;  2D0B A;  3I3W A;  1CDW A;  2DKA A;  2R5X A;  4EAI A;  5EPC A;  2EHB D;  3RPJ A;  2QRE A;  3OGD A;  1VOL B;  2HZM A;  1E42 A;  1LWV A;  2LAE A;  3ENO C;  4Q11 A;  1NH2 A;  2JHN A;  1KYF A;  2V8Q A;  3C04 A;  2O3O A;  1MP9 A;  2NOF A;  1B9K A;  3CWS A;  3DPU A;  4ROC B;  2JOI A;  2PWW A;  1P5G X;  5IYD P;  4EJY A;  1JFI C;  4ROD B;  2D0A A;  1QNB A;  4ROE B;  3I0W A;  3TDH A;  1VTO A;  5IYB P;  1K2Y X;  1YQK A;  4PY5 A;  2H5A X;  4C7P A;  1C47 A;  1TBP A;  2HZS A;  3PDK A;  3IH7 A;  1C9B B;  1QN6 A;  2NOE A;  1P5D X;  2XHI A;  3BKQ X;  3OSM A;  1KY7 A;  2FUV A;  5AN4 A;  1D3U A;  3RSM A;  1N39 A;  2FGT A;  2MJ7 A;  1AIS A;  2IV9 A;  1TBA B;  2QRC A;  2VJ0 A;  2Z0F A;  3UW2 A;  1J3M A;  4HJH A;  5KL0 A;  1M5Q 1;  2I5W A;  3EAY A;  2Y8Q A;  3OH6 A;  1YQM A;  2NOZ A;  2F7L A;  2JHJ A;  1K35 A;  2IV8 A;  1QN4 A;  3CWA A;  1PCM X;  3DPT A;  1UT4 A;  2DKD A;  1LXT A;  4WX8 A;  2MZ8 A;  1KFI A;  4EAL A;  4WZS D;  4EAK A;  5IYC P;  1RM1 A;  3D7Q A;  1EUV A;  1M3Q A;  3KRM A; 
#chains in the Genus database with same CATH homology
 3OSE A;  3TDH A;  4EAG A;  2QR1 A;  1V5S A;  3T4N A;  2Y8L A;  3TE5 A;  2YA3 A;  4EAI A;  4EAJ A;  2EHB D;  2OOX A;  2QRE A;  2QLV A;  4CFF A;  2QRC A;  2Y8Q A;  1UL7 A;  2V8Q A;  2V9J A;  2ZFD B;  2V92 A;  4EAL A;  4EAK A;  2QRD A;  2OOY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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