2V8QA

Crystal structure of the regulatory fragment of mammalian ampk in complexes with amp
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
156
structure length
102
Chain Sequence
SMAWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDEVAPRPGSHTIEFFEMCANLIKILAQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
source organism Rattus norvegicus
publication title Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
pubmed doi rcsb
molecule keywords 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1
total genus 23
structure length 102
sequence length 156
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-08-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2v8qA01
2OOYA 2QREA 4EAJA 2QRDA 2QR1A 2QRCA 3TDHA 2V8QA 2V9JA 2V92A 4CFFA 2QLVA 4EAIA 1V5SA 2OOXA 2Y8QA 3T4NA 1UL7A 4EAKA 3OSEA 2ZFDB 2Y8LA 2YA3A 3TE5A 4EALA 2EHBD 4EAGA
chains in the Genus database with same CATH superfamily
2LAEA 2MZ8A 2QRDA 2G30A 1JDYA 2O3OA 4IL8A 1NGMA 4WZSD 1E42A 2QRCA 4D7RA 4TPSA 5BMPA 3OCIA 3ULXA 1C4GA 1KY7A 3PMGA 4CFFA 1QNEA 4EJYA 3NA5A 3F10A 1K2YX 5EPCA 1PCMX 2NOIA 2HKPA 2Y8QA 3UW2A 1KY6A 2R5XA 1M3HA 1QTPA 1KO9A 1TBAB 3T4NA 1LWWA 4D7QA 1TBPA 4DULA 4WXAA 2DKAA 2NOZA 2EHBD 3F0ZA 2HL8A 3CWTA 3OSMA 4RODB 2NLVA 5F9CA 2NOLA 1PZDA 1QN6A 1QTSA 5JN5A 2NWVA 2QR1A 2D0BA 2FGTA 2JHNA 3HS8A 1P5DX 2F7LA 1Q9UA 2JOIA 2NOHA 1MP9A 3I3WA 1N39A 1VTOA 2V8QA 1QN8A 4Q11A 1UT4A 4HJHA 2V92A 5IYCP 4BJUA 1QN7A 1TUOA 1M3QA 1KYFA 1V5SA 1QNCA 2FKMX 2OOXA 3CVSA 1QN3A 2DKCA 4MRQA 5IYBP 1YTFA 3VN5A 1VTLE 2XHIA 5IYDP 4EJZA 1PVSA 3D7QA 4B0AA 2IV9A 4WX8A 3TE5A 2PWWA 3BKQX 1C9BB 1B9KA 3HS9A 4EAGA 1FN7A 1LXTA 1N3CA 1KYUA 1YQRA 2OOYA 2NOBA 1CDWA 2MJ7A 1QNBA 2HZSA 3CWAA 1KFIA 1M5Q1 1WJWA 2JHJA 3OSTA 1YQMA 1WQAA 1VKLA 2Z0FA 1N3AA 1LWYA 2NOEA 2FKFA 1DIZA 2Z8UA 3D4VA 2V9JA 1JFIC 1C47A 4EAIA 2IV8A 1P5GX 1R4XA 3EAYA 1LWVA 3SNSA 3RPJA 2DKDA 3C04A 3KTUA 3CWSA 5BMNA 3ENOC 1HU0A 3CVTA 1UL7A 3H1ZA 1T6AA 2ZFDB 2Y8LA 1NH2A 5HSHA 2HZMA 2YA3A 2YH5A 1D3UA 1QN4A 2NVMA 2NOFA 3DPTA 1YQLA 4QG5A 1KFQA 1EUVA 3ASMA 2JPIA 3RSMA 2QREA 1QN9A 3CWUA 4EAJA 1YTBA 1K35A 3CW7A 1PCJX 1UT7A 1VOKA 3TDHA 2HL9A 4C7PA 1VOLB 3N89A 5AN4A 3OH6A 1RM1A 1AISA 2QLVA 3OLPA 3OH9A 1NVPA 3OGDA 1PCZA 3PDKA 1QNAA 1J3MA 1KYDA 1QN5A 3OC3C 2H5AX 4ROEB 1EBMA 1YQKA 3DPUA 2D0AA 2I5WA 2H4LX 3ENCA 3I0WA 3I0XA 4PY5A 4EAKA 3IH7A 2FUVA 3OSEA 1XSZA 5JMVD 1TGHA 2D0CA 2VJ0A 4I8OA 4EALA 1MPGA 3EIKA 5KL0A 4ROCB 3KRMA 1W80A
chains in the Genus database with same CATH topology
2OOYA 2QREA 4EAJA 2QRDA 2QR1A 2QRCA 3TDHA 2V8QA 2V9JA 2V92A 4CFFA 2QLVA 4EAIA 1V5SA 2OOXA 2Y8QA 3T4NA 1UL7A 4EAKA 3OSEA 2ZFDB 2Y8LA 2YA3A 3TE5A 4EALA 2EHBD 4EAGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OOY A;  2QRE A;  4EAJ A;  2QRD A;  2QR1 A;  2QRC A;  3TDH A;  2V8Q A;  2V9J A;  2V92 A;  4CFF A;  2QLV A;  4EAI A;  1V5S A;  2OOX A;  2Y8Q A;  3T4N A;  1UL7 A;  4EAK A;  3OSE A;  2ZFD B;  2Y8L A;  2YA3 A;  3TE5 A;  4EAL A;  2EHB D;  4EAG A; 
#chains in the Genus database with same CATH topology
 2LAE A;  2MZ8 A;  2QRD A;  2G30 A;  1JDY A;  2O3O A;  4IL8 A;  1NGM A;  4WZS D;  1E42 A;  2QRC A;  4D7R A;  4TPS A;  5BMP A;  3OCI A;  3ULX A;  1C4G A;  1KY7 A;  3PMG A;  4CFF A;  1QNE A;  4EJY A;  3NA5 A;  3F10 A;  1K2Y X;  5EPC A;  1PCM X;  2NOI A;  2HKP A;  2Y8Q A;  3UW2 A;  1KY6 A;  2R5X A;  1M3H A;  1QTP A;  1KO9 A;  1TBA B;  3T4N A;  1LWW A;  4D7Q A;  1TBP A;  4DUL A;  4WXA A;  2DKA A;  2NOZ A;  2EHB D;  3F0Z A;  2HL8 A;  3CWT A;  3OSM A;  4ROD B;  2NLV A;  5F9C A;  2NOL A;  1PZD A;  1QN6 A;  1QTS A;  5JN5 A;  2NWV A;  2QR1 A;  2D0B A;  2FGT A;  2JHN A;  3HS8 A;  1P5D X;  2F7L A;  1Q9U A;  2JOI A;  2NOH A;  1MP9 A;  3I3W A;  1N39 A;  1VTO A;  2V8Q A;  1QN8 A;  4Q11 A;  1UT4 A;  4HJH A;  2V92 A;  5IYC P;  4BJU A;  1QN7 A;  1TUO A;  1M3Q A;  1KYF A;  1V5S A;  1QNC A;  2FKM X;  2OOX A;  3CVS A;  1QN3 A;  2DKC A;  4MRQ A;  5IYB P;  1YTF A;  3VN5 A;  1VTL E;  2XHI A;  5IYD P;  4EJZ A;  1PVS A;  3D7Q A;  4B0A A;  2IV9 A;  4WX8 A;  3TE5 A;  2PWW A;  3BKQ X;  1C9B B;  1B9K A;  3HS9 A;  4EAG A;  1FN7 A;  1LXT A;  1N3C A;  1KYU A;  1YQR A;  2OOY A;  2NOB A;  1CDW A;  2MJ7 A;  1QNB A;  2HZS A;  3CWA A;  1KFI A;  1M5Q 1;  1WJW A;  2JHJ A;  3OST A;  1YQM A;  1WQA A;  1VKL A;  2Z0F A;  1N3A A;  1LWY A;  2NOE A;  2FKF A;  1DIZ A;  2Z8U A;  3D4V A;  2V9J A;  1JFI C;  1C47 A;  4EAI A;  2IV8 A;  1P5G X;  1R4X A;  3EAY A;  1LWV A;  3SNS A;  3RPJ A;  2DKD A;  3C04 A;  3KTU A;  3CWS A;  5BMN A;  3ENO C;  1HU0 A;  3CVT A;  1UL7 A;  3H1Z A;  1T6A A;  2ZFD B;  2Y8L A;  1NH2 A;  5HSH A;  2HZM A;  2YA3 A;  2YH5 A;  1D3U A;  1QN4 A;  2NVM A;  2NOF A;  3DPT A;  1YQL A;  4QG5 A;  1KFQ A;  1EUV A;  3ASM A;  2JPI A;  3RSM A;  2QRE A;  1QN9 A;  3CWU A;  4EAJ A;  1YTB A;  1K35 A;  3CW7 A;  1PCJ X;  1UT7 A;  1VOK A;  3TDH A;  2HL9 A;  4C7P A;  1VOL B;  3N89 A;  5AN4 A;  3OH6 A;  1RM1 A;  1AIS A;  2QLV A;  3OLP A;  3OH9 A;  1NVP A;  3OGD A;  1PCZ A;  3PDK A;  1QNA A;  1J3M A;  1KYD A;  1QN5 A;  3OC3 C;  2H5A X;  4ROE B;  1EBM A;  1YQK A;  3DPU A;  2D0A A;  2I5W A;  2H4L X;  3ENC A;  3I0W A;  3I0X A;  4PY5 A;  4EAK A;  3IH7 A;  2FUV A;  3OSE A;  1XSZ A;  5JMV D;  1TGH A;  2D0C A;  2VJ0 A;  4I8O A;  4EAL A;  1MPG A;  3EIK A;  5KL0 A;  4ROC B;  3KRM A;  1W80 A; 
#chains in the Genus database with same CATH homology
 2OOY A;  2QRE A;  4EAJ A;  2QRD A;  2QR1 A;  2QRC A;  3TDH A;  2V8Q A;  2V9J A;  2V92 A;  4CFF A;  2QLV A;  4EAI A;  1V5S A;  2OOX A;  2Y8Q A;  3T4N A;  1UL7 A;  4EAK A;  3OSE A;  2ZFD B;  2Y8L A;  2YA3 A;  3TE5 A;  4EAL A;  2EHB D;  4EAG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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