2V92A

Crystal structure of the regulatory fragment of mammalian ampk in complexes with atp-amp
Total Genus 21

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
156
structure length
102
Chain Sequence
SMAWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDEVAPRPGSHTIEFFEMCANLIKILAQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1
total genus 21
structure length 102
sequence length 156
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-08-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2v92A01
2Y8QA 3OSEA 2QLVA 2V9JA 4EAJA 2EHBD 2V8QA 4CFFA 4EALA 2Y8LA 2QRCA 2OOXA 2OOYA 3TDHA 3TE5A 4EAKA 4EAIA 2YA3A 1V5SA 2QREA 2QRDA 3T4NA 2V92A 2QR1A 2ZFDB 1UL7A 4EAGA
chains in the Genus database with same CATH superfamily
1CDWA 5F9CA 3UW2A 4D7RA 4DULA 4EAJA 2V8QA 2NOHA 1LWYA 1QN3A 1PCJX 1PVSA 2Y8LA 1QN7A 1P5GX 3EIKA 2NLVA 1PCZA 1QNAA 1R4XA 3CWUA 1QNEA 4EJZA 2NOIA 1YQLA 1YQMA 3BKQX 3KRMA 4EAIA 2H5AX 3OGDA 1RM1A 5IYCP 1QTSA 4I8OA 3SNSA 3T4NA 3ASMA 5IYDP 1VTOA 1NGMA 1P5DX 1YTBA 4IL8A 2D0AA 1QTPA 1VOKA 2F7LA 1B9KA 1UL7A 2HL8A 1NVPA 4WZSD 2IV8A 3OSMA 3I0XA 4ROCB 1N3AA 3OH6A 5HSHA 1MPGA 1PZDA 2FKFA 2D0BA 2MJ7A 5KL0A 2EHBD 2D0CA 3F10A 4BJUA 3CWAA 1LWWA 2NOEA 1XSZA 3D4VA 1KFIA 3CWSA 2NVMA 3ENCA 3OLPA 2HKPA 3I3WA 2O3OA 4RODB 1E42A 1Q9UA 3DPTA 3N89A 1UT4A 4B0AA 5JMVD 2G30A 4WX8A 2PWWA 5BMNA 1YTFA 1M5Q1 1KYDA 4EAKA 4C7PA 2Z8UA 3EAYA 4QG5A 3CW7A 2QRDA 2DKAA 2Z0FA 2V92A 2QR1A 1YQKA 3KTUA 4MRQA 1KYUA 1LWVA 1UT7A 4ROEB 1D3UA 2JHNA 3OC3C 1M3HA 2HL9A 3DPUA 1K35A 2Y8QA 2QLVA 3IH7A 2V9JA 1QNBA 2IV9A 5AN4A 1KFQA 4CFFA 3CVTA 3OCIA 3CVSA 1KY7A 2QRCA 3TDHA 2I5WA 3NA5A 2JPIA 2NOFA 3ENOC 2DKCA 3TE5A 1FN7A 3OH9A 2MZ8A 1TBPA 1T6AA 1WJWA 1QN5A 2YA3A 3HS9A 1PCMX 1QNCA 2NOLA 1V5SA 2QREA 2NOZA 1W80A 1TGHA 4HJHA 5EPCA 2FUVA 2ZFDB 1YQRA 4EJYA 1N3CA 1KO9A 1KYFA 2NOBA 2FGTA 1QN9A 5IYBP 1JDYA 5JN5A 1VTLE 3CWTA 4PY5A 3OSEA 1JFIC 1QN4A 2DKDA 1VKLA 3H1ZA 3PDKA 1EUVA 1J3MA 4WXAA 2XHIA 1LXTA 4EALA 3I0WA 3C04A 1M3QA 2VJ0A 2OOXA 2OOYA 3HS8A 3RPJA 1N39A 2HZSA 3RSMA 1HU0A 1C9BB 2HZMA 1QN8A 1WQAA 3D7QA 3F0ZA 4TPSA 3ULXA 1EBMA 1C4GA 1K2YX 2R5XA 2NWVA 2JOIA 2FKMX 3OSTA 2H4LX 4Q11A 1QN6A 3VN5A 1AISA 1NH2A 1VOLB 1C47A 2JHJA 1MP9A 1TBAB 2LAEA 4D7QA 1DIZA 1TUOA 2YH5A 4EAGA 1KY6A 5BMPA 3PMGA
chains in the Genus database with same CATH topology
2Y8QA 3OSEA 2QLVA 2V9JA 4EAJA 2EHBD 2V8QA 4CFFA 4EALA 2Y8LA 2QRCA 2OOXA 2OOYA 3TDHA 3TE5A 4EAKA 4EAIA 2YA3A 1V5SA 2QREA 2QRDA 3T4NA 2V92A 2QR1A 2ZFDB 1UL7A 4EAGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y8Q A;  3OSE A;  2QLV A;  2V9J A;  4EAJ A;  2EHB D;  2V8Q A;  4CFF A;  4EAL A;  2Y8L A;  2QRC A;  2OOX A;  2OOY A;  3TDH A;  3TE5 A;  4EAK A;  4EAI A;  2YA3 A;  1V5S A;  2QRE A;  2QRD A;  3T4N A;  2V92 A;  2QR1 A;  2ZFD B;  1UL7 A;  4EAG A; 
#chains in the Genus database with same CATH topology
 1CDW A;  5F9C A;  3UW2 A;  4D7R A;  4DUL A;  4EAJ A;  2V8Q A;  2NOH A;  1LWY A;  1QN3 A;  1PCJ X;  1PVS A;  2Y8L A;  1QN7 A;  1P5G X;  3EIK A;  2NLV A;  1PCZ A;  1QNA A;  1R4X A;  3CWU A;  1QNE A;  4EJZ A;  2NOI A;  1YQL A;  1YQM A;  3BKQ X;  3KRM A;  4EAI A;  2H5A X;  3OGD A;  1RM1 A;  5IYC P;  1QTS A;  4I8O A;  3SNS A;  3T4N A;  3ASM A;  5IYD P;  1VTO A;  1NGM A;  1P5D X;  1YTB A;  4IL8 A;  2D0A A;  1QTP A;  1VOK A;  2F7L A;  1B9K A;  1UL7 A;  2HL8 A;  1NVP A;  4WZS D;  2IV8 A;  3OSM A;  3I0X A;  4ROC B;  1N3A A;  3OH6 A;  5HSH A;  1MPG A;  1PZD A;  2FKF A;  2D0B A;  2MJ7 A;  5KL0 A;  2EHB D;  2D0C A;  3F10 A;  4BJU A;  3CWA A;  1LWW A;  2NOE A;  1XSZ A;  3D4V A;  1KFI A;  3CWS A;  2NVM A;  3ENC A;  3OLP A;  2HKP A;  3I3W A;  2O3O A;  4ROD B;  1E42 A;  1Q9U A;  3DPT A;  3N89 A;  1UT4 A;  4B0A A;  5JMV D;  2G30 A;  4WX8 A;  2PWW A;  5BMN A;  1YTF A;  1M5Q 1;  1KYD A;  4EAK A;  4C7P A;  2Z8U A;  3EAY A;  4QG5 A;  3CW7 A;  2QRD A;  2DKA A;  2Z0F A;  2V92 A;  2QR1 A;  1YQK A;  3KTU A;  4MRQ A;  1KYU A;  1LWV A;  1UT7 A;  4ROE B;  1D3U A;  2JHN A;  3OC3 C;  1M3H A;  2HL9 A;  3DPU A;  1K35 A;  2Y8Q A;  2QLV A;  3IH7 A;  2V9J A;  1QNB A;  2IV9 A;  5AN4 A;  1KFQ A;  4CFF A;  3CVT A;  3OCI A;  3CVS A;  1KY7 A;  2QRC A;  3TDH A;  2I5W A;  3NA5 A;  2JPI A;  2NOF A;  3ENO C;  2DKC A;  3TE5 A;  1FN7 A;  3OH9 A;  2MZ8 A;  1TBP A;  1T6A A;  1WJW A;  1QN5 A;  2YA3 A;  3HS9 A;  1PCM X;  1QNC A;  2NOL A;  1V5S A;  2QRE A;  2NOZ A;  1W80 A;  1TGH A;  4HJH A;  5EPC A;  2FUV A;  2ZFD B;  1YQR A;  4EJY A;  1N3C A;  1KO9 A;  1KYF A;  2NOB A;  2FGT A;  1QN9 A;  5IYB P;  1JDY A;  5JN5 A;  1VTL E;  3CWT A;  4PY5 A;  3OSE A;  1JFI C;  1QN4 A;  2DKD A;  1VKL A;  3H1Z A;  3PDK A;  1EUV A;  1J3M A;  4WXA A;  2XHI A;  1LXT A;  4EAL A;  3I0W A;  3C04 A;  1M3Q A;  2VJ0 A;  2OOX A;  2OOY A;  3HS8 A;  3RPJ A;  1N39 A;  2HZS A;  3RSM A;  1HU0 A;  1C9B B;  2HZM A;  1QN8 A;  1WQA A;  3D7Q A;  3F0Z A;  4TPS A;  3ULX A;  1EBM A;  1C4G A;  1K2Y X;  2R5X A;  2NWV A;  2JOI A;  2FKM X;  3OST A;  2H4L X;  4Q11 A;  1QN6 A;  3VN5 A;  1AIS A;  1NH2 A;  1VOL B;  1C47 A;  2JHJ A;  1MP9 A;  1TBA B;  2LAE A;  4D7Q A;  1DIZ A;  1TUO A;  2YH5 A;  4EAG A;  1KY6 A;  5BMP A;  3PMG A; 
#chains in the Genus database with same CATH homology
 2Y8Q A;  3OSE A;  2QLV A;  2V9J A;  4EAJ A;  2EHB D;  2V8Q A;  4CFF A;  4EAL A;  2Y8L A;  2QRC A;  2OOX A;  2OOY A;  3TDH A;  3TE5 A;  4EAK A;  4EAI A;  2YA3 A;  1V5S A;  2QRE A;  2QRD A;  3T4N A;  2V92 A;  2QR1 A;  2ZFD B;  1UL7 A;  4EAG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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