2YA3A

Structure of the regulatory fragment of mammalian ampk in complex with coumarin adp
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
156
structure length
102
Chain Sequence
MAWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDEVAPRPGSHTIEFFEMCANLIKNSCTV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
source organism Rattus norvegicus
publication title Structure of Mammalian Ampk and its Regulation by Adp
pubmed doi rcsb
molecule keywords 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1
total genus 21
structure length 102
sequence length 156
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2011-02-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2ya3A01
2QREA 1V5SA 2QLVA 4EAGA 4EALA 2QRCA 2V9JA 2V92A 2QRDA 1UL7A 2Y8LA 2V8QA 4EAKA 2OOYA 3TE5A 3TDHA 3OSEA 2YA3A 2OOXA 4EAJA 2EHBD 4CFFA 2Y8QA 4EAIA 3T4NA 2QR1A 2ZFDB
chains in the Genus database with same CATH superfamily
2FKFA 3VN5A 2JPIA 3OSTA 3BKQX 3ENOC 1P5GX 2MZ8A 2JHNA 1P5DX 4WZSD 1C9BB 2NOZA 1WQAA 2MJ7A 2V92A 2QRDA 2D0BA 1PCMX 4WX8A 1KY6A 1TGHA 2YH5A 1VOKA 1UL7A 2R5XA 2V8QA 4EAKA 5BMNA 1QN6A 1VOLB 1LWYA 2OOYA 2NOIA 3EAYA 5EPCA 3ULXA 2HL9A 2FUVA 1N39A 1EBMA 2H4LX 4EAJA 1QN4A 1M3HA 4DULA 1QN9A 1NH2A 3OH9A 3HS9A 2G30A 2JHJA 4B0AA 1J3MA 3OLPA 3I0WA 3KRMA 4EAIA 4ROEB 2QLVA 1LWWA 2VJ0A 1JDYA 1KYDA 3F0ZA 3I0XA 1N3CA 3DPTA 3NA5A 1VTOA 1EUVA 1KFIA 1YTFA 3CWSA 1JFIC 2NOFA 1T6AA 2NVMA 1C4GA 1YQLA 1QNBA 2HZSA 1VKLA 2NWVA 5IYDP 3HS8A 3IH7A 4C7PA 1YTBA 2NOHA 2FGTA 1YQRA 1TUOA 5HSHA 1MP9A 3DPUA 3OGDA 4D7QA 1QNAA 3CVSA 2PWWA 3TDHA 2YA3A 2D0AA 1CDWA 3I3WA 3N89A 3KTUA 2JOIA 4I8OA 3H1ZA 1QNCA 5IYCP 2QR1A 1NVPA 1C47A 2ZFDB 2QREA 1V5SA 2HKPA 2D0CA 1KYUA 4TPSA 1VTLE 1QN7A 4EALA 2DKDA 3EIKA 2NOLA 1TBPA 1KYFA 1XSZA 1UT7A 2QRCA 5JMVD 1N3AA 2V9JA 2Z8UA 5AN4A 4BJUA 2O3OA 3F10A 3ENCA 2DKCA 2XHIA 2DKAA 1K35A 3PMGA 4EJZA 3CWAA 1QTSA 3PDKA 1Q9UA 5BMPA 1B9KA 3OCIA 3SNSA 1QN5A 4EJYA 2Z0FA 3CWUA 1YQKA 4PY5A 2HL8A 2I5WA 3OSEA 2OOXA 1LXTA 1UT4A 2NLVA 1R4XA 3RPJA 1HU0A 1QNEA 1WJWA 2EHBD 1E42A 1FN7A 2F7LA 1QN8A 2Y8QA 1TBAB 3T4NA 3CVTA 1LWVA 1M3QA 3D4VA 1DIZA 2IV9A 3RSMA 4WXAA 2NOEA 1PCJX 2HZMA 1KO9A 4RODB 1K2YX 4EAGA 1RM1A 2LAEA 5IYBP 2H5AX 1PCZA 1KFQA 2Y8LA 3UW2A 1PVSA 1QTPA 4IL8A 5JN5A 3OSMA 1YQMA 1KY7A 4Q11A 3CW7A 4HJHA 3D7QA 3OH6A 3TE5A 1D3UA 2FKMX 3OC3C 4QG5A 3CWTA 4MRQA 1M5Q1 3C04A 2IV8A 3ASMA 1NGMA 1AISA 1MPGA 4CFFA 1W80A 4ROCB 4D7RA 1PZDA 1QN3A 2NOBA 5F9CA 5KL0A
chains in the Genus database with same CATH topology
2QREA 1V5SA 2QLVA 4EAGA 4EALA 2QRCA 2V9JA 2V92A 2QRDA 1UL7A 2Y8LA 2V8QA 4EAKA 2OOYA 3TE5A 3TDHA 3OSEA 2YA3A 2OOXA 4EAJA 2EHBD 4CFFA 2Y8QA 4EAIA 3T4NA 2QR1A 2ZFDB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QRE A;  1V5S A;  2QLV A;  4EAG A;  4EAL A;  2QRC A;  2V9J A;  2V92 A;  2QRD A;  1UL7 A;  2Y8L A;  2V8Q A;  4EAK A;  2OOY A;  3TE5 A;  3TDH A;  3OSE A;  2YA3 A;  2OOX A;  4EAJ A;  2EHB D;  4CFF A;  2Y8Q A;  4EAI A;  3T4N A;  2QR1 A;  2ZFD B; 
#chains in the Genus database with same CATH topology
 2FKF A;  3VN5 A;  2JPI A;  3OST A;  3BKQ X;  3ENO C;  1P5G X;  2MZ8 A;  2JHN A;  1P5D X;  4WZS D;  1C9B B;  2NOZ A;  1WQA A;  2MJ7 A;  2V92 A;  2QRD A;  2D0B A;  1PCM X;  4WX8 A;  1KY6 A;  1TGH A;  2YH5 A;  1VOK A;  1UL7 A;  2R5X A;  2V8Q A;  4EAK A;  5BMN A;  1QN6 A;  1VOL B;  1LWY A;  2OOY A;  2NOI A;  3EAY A;  5EPC A;  3ULX A;  2HL9 A;  2FUV A;  1N39 A;  1EBM A;  2H4L X;  4EAJ A;  1QN4 A;  1M3H A;  4DUL A;  1QN9 A;  1NH2 A;  3OH9 A;  3HS9 A;  2G30 A;  2JHJ A;  4B0A A;  1J3M A;  3OLP A;  3I0W A;  3KRM A;  4EAI A;  4ROE B;  2QLV A;  1LWW A;  2VJ0 A;  1JDY A;  1KYD A;  3F0Z A;  3I0X A;  1N3C A;  3DPT A;  3NA5 A;  1VTO A;  1EUV A;  1KFI A;  1YTF A;  3CWS A;  1JFI C;  2NOF A;  1T6A A;  2NVM A;  1C4G A;  1YQL A;  1QNB A;  2HZS A;  1VKL A;  2NWV A;  5IYD P;  3HS8 A;  3IH7 A;  4C7P A;  1YTB A;  2NOH A;  2FGT A;  1YQR A;  1TUO A;  5HSH A;  1MP9 A;  3DPU A;  3OGD A;  4D7Q A;  1QNA A;  3CVS A;  2PWW A;  3TDH A;  2YA3 A;  2D0A A;  1CDW A;  3I3W A;  3N89 A;  3KTU A;  2JOI A;  4I8O A;  3H1Z A;  1QNC A;  5IYC P;  2QR1 A;  1NVP A;  1C47 A;  2ZFD B;  2QRE A;  1V5S A;  2HKP A;  2D0C A;  1KYU A;  4TPS A;  1VTL E;  1QN7 A;  4EAL A;  2DKD A;  3EIK A;  2NOL A;  1TBP A;  1KYF A;  1XSZ A;  1UT7 A;  2QRC A;  5JMV D;  1N3A A;  2V9J A;  2Z8U A;  5AN4 A;  4BJU A;  2O3O A;  3F10 A;  3ENC A;  2DKC A;  2XHI A;  2DKA A;  1K35 A;  3PMG A;  4EJZ A;  3CWA A;  1QTS A;  3PDK A;  1Q9U A;  5BMP A;  1B9K A;  3OCI A;  3SNS A;  1QN5 A;  4EJY A;  2Z0F A;  3CWU A;  1YQK A;  4PY5 A;  2HL8 A;  2I5W A;  3OSE A;  2OOX A;  1LXT A;  1UT4 A;  2NLV A;  1R4X A;  3RPJ A;  1HU0 A;  1QNE A;  1WJW A;  2EHB D;  1E42 A;  1FN7 A;  2F7L A;  1QN8 A;  2Y8Q A;  1TBA B;  3T4N A;  3CVT A;  1LWV A;  1M3Q A;  3D4V A;  1DIZ A;  2IV9 A;  3RSM A;  4WXA A;  2NOE A;  1PCJ X;  2HZM A;  1KO9 A;  4ROD B;  1K2Y X;  4EAG A;  1RM1 A;  2LAE A;  5IYB P;  2H5A X;  1PCZ A;  1KFQ A;  2Y8L A;  3UW2 A;  1PVS A;  1QTP A;  4IL8 A;  5JN5 A;  3OSM A;  1YQM A;  1KY7 A;  4Q11 A;  3CW7 A;  4HJH A;  3D7Q A;  3OH6 A;  3TE5 A;  1D3U A;  2FKM X;  3OC3 C;  4QG5 A;  3CWT A;  4MRQ A;  1M5Q 1;  3C04 A;  2IV8 A;  3ASM A;  1NGM A;  1AIS A;  1MPG A;  4CFF A;  1W80 A;  4ROC B;  4D7R A;  1PZD A;  1QN3 A;  2NOB A;  5F9C A;  5KL0 A; 
#chains in the Genus database with same CATH homology
 2QRE A;  1V5S A;  2QLV A;  4EAG A;  4EAL A;  2QRC A;  2V9J A;  2V92 A;  2QRD A;  1UL7 A;  2Y8L A;  2V8Q A;  4EAK A;  2OOY A;  3TE5 A;  3TDH A;  3OSE A;  2YA3 A;  2OOX A;  4EAJ A;  2EHB D;  4CFF A;  2Y8Q A;  4EAI A;  3T4N A;  2QR1 A;  2ZFD B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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