2QR1A

Crystal structure of the adenylate sensor from amp-activated protein kinase in complex with adp
Total Genus 32
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
126
structure length
116
Chain Sequence
KWHFGVRCRGDAPEILLAVYRALQRAGAQFTVPKPVNGKYRSDMYTIKSRWEIPHCKREGKNTYAYIELQLYEVMPGCFMLDVKSNGYKDIYSHDLKSSFPFLDLCAMLVCKLFSA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insight into AMPK Regulation: ADP Comes into Play.
pubmed doi rcsb
molecule tags Transferase
source organism Schizosaccharomyces pombe
molecule keywords SNF1-like protein kinase ssp2
total genus 32
structure length 116
sequence length 126
chains with identical sequence C
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-07-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16579 AdenylateSensor Adenylate sensor of SNF1-like protein kinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2qr1A00
3OSEA 2ZFDB 2Y8QA 2QLVA 4EAKA 4CFFA 2QRCA 2V8QA 2QRDA 2OOXA 3TDHA 3TE5A 4EALA 2V92A 4EAIA 2V9JA 2OOYA 4EAGA 4EAJA 3T4NA 2YA3A 2EHBD 2Y8LA 2QREA 1UL7A 1V5SA 2QR1A
chains in the Genus database with same CATH superfamily
1KY7A 1PCMX 3OGDA 5BMPA 4IL8A 1UT4A 1R4XA 2F7LA 1UT7A 4ROCB 1EBMA 3OSTA 3OH9A 3DPTA 2QRCA 2DKDA 1LWVA 4ROEB 1YQRA 2NVMA 1QN6A 1QTSA 3KRMA 2OOXA 3SNSA 3H1ZA 2NOZA 1PCZA 1LWWA 1N39A 1QN5A 2JHNA 3NA5A 4WXAA 3IH7A 2JOIA 4Q11A 4C7PA 4EAJA 2JHJA 1QN8A 2NOHA 3PMGA 1QN9A 2EHBD 3D7QA 5HSHA 5IYCP 4D7RA 2HL8A 3CWTA 2YH5A 1V5SA 3BKQX 1VTOA 5EPCA 1EUVA 2HKPA 3ASMA 2DKCA 2O3OA 2Y8QA 1TBAB 3EIKA 3CVSA 2QLVA 4EAKA 1TGHA 3OCIA 3I0XA 1TUOA 1PVSA 2HZSA 2VJ0A 3CWAA 1CDWA 1LWYA 1VOLB 3ULXA 3RSMA 3TE5A 4EALA 3OH6A 1M3HA 2PWWA 2I5WA 4I8OA 4B0AA 1QNCA 4WX8A 1Q9UA 3ENCA 2NOBA 1P5DX 1MPGA 3T4NA 3RPJA 2IV9A 3UW2A 3CWUA 1KFIA 1J3MA 1KYUA 1YQMA 1QN4A 3I0WA 1JDYA 1C9BB 4RODB 1HU0A 4D7QA 1KFQA 3I3WA 3OSEA 1K35A 3ENOC 2NOFA 2NOIA 4PY5A 1E42A 1KY6A 1PZDA 4EJZA 4DULA 2V8QA 1QN3A 3CWSA 2R5XA 1VOKA 4HJHA 1WQAA 3TDHA 3OLPA 1W80A 2H4LX 2HZMA 2XHIA 2V9JA 1B9KA 2OOYA 1M5Q1 2H5AX 4EAGA 5IYBP 2FUVA 1QNAA 1DIZA 4MRQA 2YA3A 3VN5A 5BMNA 3OC3C 2HL9A 2Y8LA 3C04A 1KO9A 2QREA 1UL7A 3OSMA 5KL0A 1FN7A 2NOEA 1VKLA 1KYDA 1YTBA 2DKAA 2QR1A 1XSZA 4WZSD 1YQKA 1M3QA 3F0ZA 1YQLA 2NOLA 3DPUA 2ZFDB 1NH2A 5AN4A 2NLVA 2JPIA 3PDKA 4CFFA 2MZ8A 2IV8A 1QTPA 1NGMA 5F9CA 2Z8UA 1QNEA 3CVTA 1T6AA 2D0BA 2D0AA 3F10A 1MP9A 1TBPA 2D0CA 2QRDA 3D4VA 3CW7A 4TPSA 1VTLE 1N3AA 4EJYA 1NVPA 2FKMX 2G30A 1JFIC 2V92A 1D3UA 1K2YX 2MJ7A 1RM1A 4QG5A 3HS9A 2FKFA 4EAIA 3EAYA 3N89A 1YTFA 1P5GX 2Z0FA 2LAEA 5JMVD 1AISA 3KTUA 1LXTA 3HS8A 5IYDP 1KYFA 1N3CA 1WJWA 1C47A 1PCJX 2NWVA 1C4GA 1QNBA 1QN7A 5JN5A 4BJUA 2FGTA
chains in the Genus database with same CATH topology
3OSEA 2ZFDB 2Y8QA 2QLVA 4EAKA 4CFFA 2QRCA 2V8QA 2QRDA 2OOXA 3TDHA 3TE5A 4EALA 2V92A 4EAIA 2V9JA 2OOYA 4EAGA 4EAJA 3T4NA 2YA3A 2EHBD 2Y8LA 2QREA 1UL7A 1V5SA 2QR1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OSE A;  2ZFD B;  2Y8Q A;  2QLV A;  4EAK A;  4CFF A;  2QRC A;  2V8Q A;  2QRD A;  2OOX A;  3TDH A;  3TE5 A;  4EAL A;  2V92 A;  4EAI A;  2V9J A;  2OOY A;  4EAG A;  4EAJ A;  3T4N A;  2YA3 A;  2EHB D;  2Y8L A;  2QRE A;  1UL7 A;  1V5S A;  2QR1 A; 
#chains in the Genus database with same CATH topology
 1KY7 A;  1PCM X;  3OGD A;  5BMP A;  4IL8 A;  1UT4 A;  1R4X A;  2F7L A;  1UT7 A;  4ROC B;  1EBM A;  3OST A;  3OH9 A;  3DPT A;  2QRC A;  2DKD A;  1LWV A;  4ROE B;  1YQR A;  2NVM A;  1QN6 A;  1QTS A;  3KRM A;  2OOX A;  3SNS A;  3H1Z A;  2NOZ A;  1PCZ A;  1LWW A;  1N39 A;  1QN5 A;  2JHN A;  3NA5 A;  4WXA A;  3IH7 A;  2JOI A;  4Q11 A;  4C7P A;  4EAJ A;  2JHJ A;  1QN8 A;  2NOH A;  3PMG A;  1QN9 A;  2EHB D;  3D7Q A;  5HSH A;  5IYC P;  4D7R A;  2HL8 A;  3CWT A;  2YH5 A;  1V5S A;  3BKQ X;  1VTO A;  5EPC A;  1EUV A;  2HKP A;  3ASM A;  2DKC A;  2O3O A;  2Y8Q A;  1TBA B;  3EIK A;  3CVS A;  2QLV A;  4EAK A;  1TGH A;  3OCI A;  3I0X A;  1TUO A;  1PVS A;  2HZS A;  2VJ0 A;  3CWA A;  1CDW A;  1LWY A;  1VOL B;  3ULX A;  3RSM A;  3TE5 A;  4EAL A;  3OH6 A;  1M3H A;  2PWW A;  2I5W A;  4I8O A;  4B0A A;  1QNC A;  4WX8 A;  1Q9U A;  3ENC A;  2NOB A;  1P5D X;  1MPG A;  3T4N A;  3RPJ A;  2IV9 A;  3UW2 A;  3CWU A;  1KFI A;  1J3M A;  1KYU A;  1YQM A;  1QN4 A;  3I0W A;  1JDY A;  1C9B B;  4ROD B;  1HU0 A;  4D7Q A;  1KFQ A;  3I3W A;  3OSE A;  1K35 A;  3ENO C;  2NOF A;  2NOI A;  4PY5 A;  1E42 A;  1KY6 A;  1PZD A;  4EJZ A;  4DUL A;  2V8Q A;  1QN3 A;  3CWS A;  2R5X A;  1VOK A;  4HJH A;  1WQA A;  3TDH A;  3OLP A;  1W80 A;  2H4L X;  2HZM A;  2XHI A;  2V9J A;  1B9K A;  2OOY A;  1M5Q 1;  2H5A X;  4EAG A;  5IYB P;  2FUV A;  1QNA A;  1DIZ A;  4MRQ A;  2YA3 A;  3VN5 A;  5BMN A;  3OC3 C;  2HL9 A;  2Y8L A;  3C04 A;  1KO9 A;  2QRE A;  1UL7 A;  3OSM A;  5KL0 A;  1FN7 A;  2NOE A;  1VKL A;  1KYD A;  1YTB A;  2DKA A;  2QR1 A;  1XSZ A;  4WZS D;  1YQK A;  1M3Q A;  3F0Z A;  1YQL A;  2NOL A;  3DPU A;  2ZFD B;  1NH2 A;  5AN4 A;  2NLV A;  2JPI A;  3PDK A;  4CFF A;  2MZ8 A;  2IV8 A;  1QTP A;  1NGM A;  5F9C A;  2Z8U A;  1QNE A;  3CVT A;  1T6A A;  2D0B A;  2D0A A;  3F10 A;  1MP9 A;  1TBP A;  2D0C A;  2QRD A;  3D4V A;  3CW7 A;  4TPS A;  1VTL E;  1N3A A;  4EJY A;  1NVP A;  2FKM X;  2G30 A;  1JFI C;  2V92 A;  1D3U A;  1K2Y X;  2MJ7 A;  1RM1 A;  4QG5 A;  3HS9 A;  2FKF A;  4EAI A;  3EAY A;  3N89 A;  1YTF A;  1P5G X;  2Z0F A;  2LAE A;  5JMV D;  1AIS A;  3KTU A;  1LXT A;  3HS8 A;  5IYD P;  1KYF A;  1N3C A;  1WJW A;  1C47 A;  1PCJ X;  2NWV A;  1C4G A;  1QNB A;  1QN7 A;  5JN5 A;  4BJU A;  2FGT A; 
#chains in the Genus database with same CATH homology
 3OSE A;  2ZFD B;  2Y8Q A;  2QLV A;  4EAK A;  4CFF A;  2QRC A;  2V8Q A;  2QRD A;  2OOX A;  3TDH A;  3TE5 A;  4EAL A;  2V92 A;  4EAI A;  2V9J A;  2OOY A;  4EAG A;  4EAJ A;  3T4N A;  2YA3 A;  2EHB D;  2Y8L A;  2QRE A;  1UL7 A;  1V5S A;  2QR1 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...