2QRCA

Crystal structure of the adenylate sensor from amp-activated protein kinase in complex with adp and amp
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
126
structure length
116
Chain Sequence
KWHFGVRCRGDAPEILLAVYRALQRAGAQFTVPKPVNGKYRSDMYTIKSRWEIPHCKREGKNTYAYIELQLYEVMPGCFMLDVKSNGYKDIYSHDLKSSFPFLDLCAMLVCKLFSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insight into AMPK Regulation: ADP Comes into Play.
pubmed doi rcsb
molecule tags Transferase
source organism Schizosaccharomyces pombe
molecule keywords SNF1-like protein kinase ssp2
total genus 32
structure length 116
sequence length 126
chains with identical sequence C
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16579 AdenylateSensor Adenylate sensor of SNF1-like protein kinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2qrcA00
2YA3A 2OOYA 1UL7A 2ZFDB 3OSEA 2EHBD 4CFFA 2QR1A 4EAGA 2Y8QA 1V5SA 3TDHA 4EAKA 4EALA 2QREA 2Y8LA 2QLVA 3TE5A 3T4NA 4EAIA 2V92A 2QRDA 2QRCA 2V9JA 4EAJA 2OOXA 2V8QA
chains in the Genus database with same CATH superfamily
3HS8A 3CVSA 3OLPA 2FKFA 2LAEA 4EJZA 2H4LX 2IV9A 3N89A 1YTFA 3TDHA 4MRQA 4EALA 3OH6A 2NOLA 1WJWA 2QREA 5AN4A 1KFQA 4QG5A 2XHIA 2I5WA 2PWWA 3OCIA 1C4GA 2JPIA 3DPTA 3SNSA 1KYDA 3OH9A 1T6AA 1KO9A 2V92A 4EAIA 1QN8A 1QN6A 1TBAB 2R5XA 1VTLE 1FN7A 3ASMA 4RODB 4EAJA 1YQKA 1NGMA 1Q9UA 2JHJA 1PZDA 1EUVA 2DKDA 2OOXA 1RM1A 1M5Q1 3I0WA 4WX8A 2D0AA 1D3UA 1QN5A 4D7QA 4PY5A 2HZSA 1M3HA 1QN9A 3ENCA 2NOZA 4I8OA 1AISA 3H1ZA 3CWTA 2ZFDB 3OSEA 2EHBD 1W80A 1LWVA 2JOIA 3BKQX 2Y8QA 1V5SA 1B9KA 2MJ7A 3D4VA 4WXAA 3F10A 3OC3C 5BMNA 4Q11A 3NA5A 2NOIA 1VKLA 1R4XA 3ULXA 3CWAA 3D7QA 2IV8A 3CWUA 2MZ8A 2VJ0A 4C7PA 2NOEA 2NVMA 3T4NA 1QTSA 1JDYA 3OGDA 1NH2A 1YQMA 5JMVD 5IYCP 1WQAA 4DULA 2QRCA 1JFIC 5EPCA 2O3OA 3VN5A 3PMGA 3I3WA 1QNCA 3HS9A 3OSMA 1KY6A 4TPSA 1N3CA 2JHNA 1PVSA 2NLVA 1K35A 2DKCA 1PCZA 1XSZA 2OOYA 1KY7A 2YA3A 1NVPA 5JN5A 1LXTA 1QTPA 1UL7A 3UW2A 2NOBA 1TUOA 2Z0FA 3PDKA 4CFFA 2QR1A 5F9CA 1LWWA 1QN4A 3IH7A 1N39A 2Z8UA 3ENOC 2F7LA 2H5AX 1YTBA 1MP9A 5IYBP 2DKAA 3RPJA 4ROCB 2NOFA 2FKMX 2Y8LA 1YQRA 4WZSD 3CVTA 2QLVA 1LWYA 3CW7A 3I0XA 1YQLA 2D0CA 1VTOA 2HKPA 1M3QA 3C04A 1C9BB 1P5DX 3F0ZA 2HZMA 2QRDA 1E42A 1TBPA 2NWVA 2V9JA 2HL9A 1QNEA 5HSHA 4IL8A 1TGHA 1VOLB 1CDWA 5BMPA 1N3AA 3KTUA 2HL8A 1KYUA 4EAGA 2FUVA 3KRMA 4HJHA 1EBMA 1QN3A 1PCMX 4EAKA 4EJYA 1PCJX 3DPUA 1K2YX 5KL0A 1VOKA 1P5GX 1HU0A 3TE5A 4BJUA 5IYDP 2YH5A 1KFIA 3OSTA 2FGTA 3EIKA 2NOHA 2D0BA 1QNAA 1KYFA 2G30A 3CWSA 1UT7A 1J3MA 4ROEB 1C47A 4B0AA 1QN7A 1DIZA 4D7RA 3RSMA 3EAYA 2V8QA 1MPGA 1UT4A 1QNBA
chains in the Genus database with same CATH topology
2YA3A 2OOYA 1UL7A 2ZFDB 3OSEA 2EHBD 4CFFA 2QR1A 4EAGA 2Y8QA 1V5SA 3TDHA 4EAKA 4EALA 2QREA 2Y8LA 2QLVA 3TE5A 3T4NA 4EAIA 2V92A 2QRDA 2QRCA 2V9JA 4EAJA 2OOXA 2V8QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YA3 A;  2OOY A;  1UL7 A;  2ZFD B;  3OSE A;  2EHB D;  4CFF A;  2QR1 A;  4EAG A;  2Y8Q A;  1V5S A;  3TDH A;  4EAK A;  4EAL A;  2QRE A;  2Y8L A;  2QLV A;  3TE5 A;  3T4N A;  4EAI A;  2V92 A;  2QRD A;  2QRC A;  2V9J A;  4EAJ A;  2OOX A;  2V8Q A; 
#chains in the Genus database with same CATH topology
 3HS8 A;  3CVS A;  3OLP A;  2FKF A;  2LAE A;  4EJZ A;  2H4L X;  2IV9 A;  3N89 A;  1YTF A;  3TDH A;  4MRQ A;  4EAL A;  3OH6 A;  2NOL A;  1WJW A;  2QRE A;  5AN4 A;  1KFQ A;  4QG5 A;  2XHI A;  2I5W A;  2PWW A;  3OCI A;  1C4G A;  2JPI A;  3DPT A;  3SNS A;  1KYD A;  3OH9 A;  1T6A A;  1KO9 A;  2V92 A;  4EAI A;  1QN8 A;  1QN6 A;  1TBA B;  2R5X A;  1VTL E;  1FN7 A;  3ASM A;  4ROD B;  4EAJ A;  1YQK A;  1NGM A;  1Q9U A;  2JHJ A;  1PZD A;  1EUV A;  2DKD A;  2OOX A;  1RM1 A;  1M5Q 1;  3I0W A;  4WX8 A;  2D0A A;  1D3U A;  1QN5 A;  4D7Q A;  4PY5 A;  2HZS A;  1M3H A;  1QN9 A;  3ENC A;  2NOZ A;  4I8O A;  1AIS A;  3H1Z A;  3CWT A;  2ZFD B;  3OSE A;  2EHB D;  1W80 A;  1LWV A;  2JOI A;  3BKQ X;  2Y8Q A;  1V5S A;  1B9K A;  2MJ7 A;  3D4V A;  4WXA A;  3F10 A;  3OC3 C;  5BMN A;  4Q11 A;  3NA5 A;  2NOI A;  1VKL A;  1R4X A;  3ULX A;  3CWA A;  3D7Q A;  2IV8 A;  3CWU A;  2MZ8 A;  2VJ0 A;  4C7P A;  2NOE A;  2NVM A;  3T4N A;  1QTS A;  1JDY A;  3OGD A;  1NH2 A;  1YQM A;  5JMV D;  5IYC P;  1WQA A;  4DUL A;  2QRC A;  1JFI C;  5EPC A;  2O3O A;  3VN5 A;  3PMG A;  3I3W A;  1QNC A;  3HS9 A;  3OSM A;  1KY6 A;  4TPS A;  1N3C A;  2JHN A;  1PVS A;  2NLV A;  1K35 A;  2DKC A;  1PCZ A;  1XSZ A;  2OOY A;  1KY7 A;  2YA3 A;  1NVP A;  5JN5 A;  1LXT A;  1QTP A;  1UL7 A;  3UW2 A;  2NOB A;  1TUO A;  2Z0F A;  3PDK A;  4CFF A;  2QR1 A;  5F9C A;  1LWW A;  1QN4 A;  3IH7 A;  1N39 A;  2Z8U A;  3ENO C;  2F7L A;  2H5A X;  1YTB A;  1MP9 A;  5IYB P;  2DKA A;  3RPJ A;  4ROC B;  2NOF A;  2FKM X;  2Y8L A;  1YQR A;  4WZS D;  3CVT A;  2QLV A;  1LWY A;  3CW7 A;  3I0X A;  1YQL A;  2D0C A;  1VTO A;  2HKP A;  1M3Q A;  3C04 A;  1C9B B;  1P5D X;  3F0Z A;  2HZM A;  2QRD A;  1E42 A;  1TBP A;  2NWV A;  2V9J A;  2HL9 A;  1QNE A;  5HSH A;  4IL8 A;  1TGH A;  1VOL B;  1CDW A;  5BMP A;  1N3A A;  3KTU A;  2HL8 A;  1KYU A;  4EAG A;  2FUV A;  3KRM A;  4HJH A;  1EBM A;  1QN3 A;  1PCM X;  4EAK A;  4EJY A;  1PCJ X;  3DPU A;  1K2Y X;  5KL0 A;  1VOK A;  1P5G X;  1HU0 A;  3TE5 A;  4BJU A;  5IYD P;  2YH5 A;  1KFI A;  3OST A;  2FGT A;  3EIK A;  2NOH A;  2D0B A;  1QNA A;  1KYF A;  2G30 A;  3CWS A;  1UT7 A;  1J3M A;  4ROE B;  1C47 A;  4B0A A;  1QN7 A;  1DIZ A;  4D7R A;  3RSM A;  3EAY A;  2V8Q A;  1MPG A;  1UT4 A;  1QNB A; 
#chains in the Genus database with same CATH homology
 2YA3 A;  2OOY A;  1UL7 A;  2ZFD B;  3OSE A;  2EHB D;  4CFF A;  2QR1 A;  4EAG A;  2Y8Q A;  1V5S A;  3TDH A;  4EAK A;  4EAL A;  2QRE A;  2Y8L A;  2QLV A;  3TE5 A;  3T4N A;  4EAI A;  2V92 A;  2QRD A;  2QRC A;  2V9J A;  4EAJ A;  2OOX A;  2V8Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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