2QRDA

Crystal structure of the adenylate sensor from amp-activated protein kinase in complex with adp and atp
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
127
structure length
114
Chain Sequence
NKWHFGVRCRGDAPEILLAVYRALQRAGAQFTVPKPVNGKYRSDMYTIKSRWEIPHCKREGKNTYAYIELQLYEVMPGCFMLDVKSNGYKDIYSKSSFPFLDLCAMLVCKLFSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insight into AMPK Regulation: ADP Comes into Play.
pubmed doi rcsb
molecule tags Transferase
source organism Schizosaccharomyces pombe
molecule keywords SNF1-like protein kinase ssp2
total genus 29
structure length 114
sequence length 127
chains with identical sequence C
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16579 AdenylateSensor Adenylate sensor of SNF1-like protein kinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2qrdA00
2QRCA 4EAKA 3OSEA 1UL7A 3TE5A 2Y8QA 2QREA 2QRDA 1V5SA 2Y8LA 3TDHA 4EAGA 3T4NA 2ZFDB 2OOYA 2V92A 4CFFA 2QLVA 2EHBD 2V8QA 2OOXA 2YA3A 4EAIA 4EAJA 2QR1A 4EALA 2V9JA
chains in the Genus database with same CATH superfamily
1Q9UA 3IH7A 3CVTA 3CWUA 1QN3A 1M3QA 1EBMA 3OSEA 3OLPA 3CWSA 4WX8A 3TE5A 1VOKA 2NWVA 5JMVD 3CWAA 1QNEA 1NGMA 3F10A 1V5SA 3UW2A 4WZSD 1KYUA 1KFQA 3RPJA 4ROEB 1KY7A 1WQAA 4EAGA 1RM1A 2NOEA 1MP9A 2FGTA 2ZFDB 1W80A 1N3AA 5IYDP 2V92A 3OC3C 4CFFA 3ENOC 4C7PA 2DKAA 1N3CA 5IYCP 1QTSA 4TPSA 2NOIA 1TBAB 1AISA 3EAYA 1QN6A 2IV8A 2JOIA 3OH9A 3I3WA 2NOBA 1KO9A 1M5Q1 4EALA 1NVPA 1VTOA 3ENCA 4EJZA 1PVSA 3OSMA 3VN5A 1QNCA 3I0WA 2NOLA 1QN4A 2XHIA 1KFIA 2H4LX 1PCZA 1E42A 1KYFA 3OCIA 1QNBA 2DKDA 2QRDA 4WXAA 1QNAA 2LAEA 5KL0A 5AN4A 2HL9A 3TDHA 2D0AA 2NOFA 2D0BA 1QN9A 2HKPA 3T4NA 4IL8A 1KYDA 1PZDA 5F9CA 2R5XA 1VKLA 3NA5A 1JDYA 3ULXA 4D7QA 4DULA 3KRMA 1VTLE 4BJUA 1D3UA 1J3MA 3D7QA 2FUVA 1EUVA 2JHJA 2OOXA 1VOLB 2PWWA 1PCJX 3CVSA 1FN7A 5HSHA 2YA3A 1C9BB 1MPGA 2FKFA 1T6AA 4EAIA 4EAJA 5BMNA 1LXTA 1KY6A 2V9JA 3KTUA 4B0AA 3RSMA 1QN7A 2JPIA 3CW7A 1C47A 2Z0FA 3OH6A 2IV9A 4ROCB 2Y8QA 2VJ0A 4D7RA 1WJWA 1LWVA 1JFIC 1B9KA 2I5WA 4HJHA 4I8OA 4MRQA 1NH2A 2MJ7A 2OOYA 5BMPA 2HZSA 1YQRA 1R4XA 1QN5A 2EHBD 3OGDA 1UT4A 3F0ZA 3DPUA 1LWWA 1QTPA 1XSZA 2Z8UA 1LWYA 1DIZA 2NVMA 1P5GX 4RODB 3H1ZA 3DPTA 1YTBA 2QRCA 1P5DX 1TBPA 2FKMX 4Q11A 4EAKA 3C04A 3D4VA 4PY5A 1UL7A 2O3OA 1QN8A 5JN5A 3PMGA 3ASMA 2F7LA 1C4GA 3PDKA 3CWTA 4QG5A 2YH5A 3N89A 2HZMA 2QREA 1YQMA 2MZ8A 2Y8LA 1YTFA 2NLVA 1M3HA 2NOZA 2JHNA 1TGHA 2D0CA 1TUOA 1YQLA 5EPCA 2QLVA 3OSTA 3HS8A 2NOHA 3SNSA 3I0XA 2QR1A 2V8QA 1YQKA 2HL8A 3BKQX 1HU0A 5IYBP 1K35A 2DKCA 1CDWA 3EIKA 1K2YX 1N39A 3HS9A 2G30A 4EJYA 1PCMX 2H5AX 1UT7A
chains in the Genus database with same CATH topology
2QRCA 4EAKA 3OSEA 1UL7A 3TE5A 2Y8QA 2QREA 2QRDA 1V5SA 2Y8LA 3TDHA 4EAGA 3T4NA 2ZFDB 2OOYA 2V92A 4CFFA 2QLVA 2EHBD 2V8QA 2OOXA 2YA3A 4EAIA 4EAJA 2QR1A 4EALA 2V9JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QRC A;  4EAK A;  3OSE A;  1UL7 A;  3TE5 A;  2Y8Q A;  2QRE A;  2QRD A;  1V5S A;  2Y8L A;  3TDH A;  4EAG A;  3T4N A;  2ZFD B;  2OOY A;  2V92 A;  4CFF A;  2QLV A;  2EHB D;  2V8Q A;  2OOX A;  2YA3 A;  4EAI A;  4EAJ A;  2QR1 A;  4EAL A;  2V9J A; 
#chains in the Genus database with same CATH topology
 1Q9U A;  3IH7 A;  3CVT A;  3CWU A;  1QN3 A;  1M3Q A;  1EBM A;  3OSE A;  3OLP A;  3CWS A;  4WX8 A;  3TE5 A;  1VOK A;  2NWV A;  5JMV D;  3CWA A;  1QNE A;  1NGM A;  3F10 A;  1V5S A;  3UW2 A;  4WZS D;  1KYU A;  1KFQ A;  3RPJ A;  4ROE B;  1KY7 A;  1WQA A;  4EAG A;  1RM1 A;  2NOE A;  1MP9 A;  2FGT A;  2ZFD B;  1W80 A;  1N3A A;  5IYD P;  2V92 A;  3OC3 C;  4CFF A;  3ENO C;  4C7P A;  2DKA A;  1N3C A;  5IYC P;  1QTS A;  4TPS A;  2NOI A;  1TBA B;  1AIS A;  3EAY A;  1QN6 A;  2IV8 A;  2JOI A;  3OH9 A;  3I3W A;  2NOB A;  1KO9 A;  1M5Q 1;  4EAL A;  1NVP A;  1VTO A;  3ENC A;  4EJZ A;  1PVS A;  3OSM A;  3VN5 A;  1QNC A;  3I0W A;  2NOL A;  1QN4 A;  2XHI A;  1KFI A;  2H4L X;  1PCZ A;  1E42 A;  1KYF A;  3OCI A;  1QNB A;  2DKD A;  2QRD A;  4WXA A;  1QNA A;  2LAE A;  5KL0 A;  5AN4 A;  2HL9 A;  3TDH A;  2D0A A;  2NOF A;  2D0B A;  1QN9 A;  2HKP A;  3T4N A;  4IL8 A;  1KYD A;  1PZD A;  5F9C A;  2R5X A;  1VKL A;  3NA5 A;  1JDY A;  3ULX A;  4D7Q A;  4DUL A;  3KRM A;  1VTL E;  4BJU A;  1D3U A;  1J3M A;  3D7Q A;  2FUV A;  1EUV A;  2JHJ A;  2OOX A;  1VOL B;  2PWW A;  1PCJ X;  3CVS A;  1FN7 A;  5HSH A;  2YA3 A;  1C9B B;  1MPG A;  2FKF A;  1T6A A;  4EAI A;  4EAJ A;  5BMN A;  1LXT A;  1KY6 A;  2V9J A;  3KTU A;  4B0A A;  3RSM A;  1QN7 A;  2JPI A;  3CW7 A;  1C47 A;  2Z0F A;  3OH6 A;  2IV9 A;  4ROC B;  2Y8Q A;  2VJ0 A;  4D7R A;  1WJW A;  1LWV A;  1JFI C;  1B9K A;  2I5W A;  4HJH A;  4I8O A;  4MRQ A;  1NH2 A;  2MJ7 A;  2OOY A;  5BMP A;  2HZS A;  1YQR A;  1R4X A;  1QN5 A;  2EHB D;  3OGD A;  1UT4 A;  3F0Z A;  3DPU A;  1LWW A;  1QTP A;  1XSZ A;  2Z8U A;  1LWY A;  1DIZ A;  2NVM A;  1P5G X;  4ROD B;  3H1Z A;  3DPT A;  1YTB A;  2QRC A;  1P5D X;  1TBP A;  2FKM X;  4Q11 A;  4EAK A;  3C04 A;  3D4V A;  4PY5 A;  1UL7 A;  2O3O A;  1QN8 A;  5JN5 A;  3PMG A;  3ASM A;  2F7L A;  1C4G A;  3PDK A;  3CWT A;  4QG5 A;  2YH5 A;  3N89 A;  2HZM A;  2QRE A;  1YQM A;  2MZ8 A;  2Y8L A;  1YTF A;  2NLV A;  1M3H A;  2NOZ A;  2JHN A;  1TGH A;  2D0C A;  1TUO A;  1YQL A;  5EPC A;  2QLV A;  3OST A;  3HS8 A;  2NOH A;  3SNS A;  3I0X A;  2QR1 A;  2V8Q A;  1YQK A;  2HL8 A;  3BKQ X;  1HU0 A;  5IYB P;  1K35 A;  2DKC A;  1CDW A;  3EIK A;  1K2Y X;  1N39 A;  3HS9 A;  2G30 A;  4EJY A;  1PCM X;  2H5A X;  1UT7 A; 
#chains in the Genus database with same CATH homology
 2QRC A;  4EAK A;  3OSE A;  1UL7 A;  3TE5 A;  2Y8Q A;  2QRE A;  2QRD A;  1V5S A;  2Y8L A;  3TDH A;  4EAG A;  3T4N A;  2ZFD B;  2OOY A;  2V92 A;  4CFF A;  2QLV A;  2EHB D;  2V8Q A;  2OOX A;  2YA3 A;  4EAI A;  4EAJ A;  2QR1 A;  4EAL A;  2V9J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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