2V8QA

Crystal structure of the regulatory fragment of mammalian ampk in complexes with amp
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
156
structure length
102
Chain Sequence
SMAWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDEVAPRPGSHTIEFFEMCANLIKILAQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1
total genus 23
structure length 102
sequence length 156
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-08-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2v8qA01
3TE5A 2V8QA 2V92A 1V5SA 2OOYA 2Y8QA 3T4NA 2EHBD 2Y8LA 2QRDA 2YA3A 2QR1A 2V9JA 2OOXA 1UL7A 2QLVA 4CFFA 2QREA 4EALA 3OSEA 3TDHA 2QRCA 4EAIA 4EAKA 4EAJA 4EAGA 2ZFDB
chains in the Genus database with same CATH superfamily
3KTUA 5HSHA 3CW7A 3CVSA 5F9CA 2V92A 3DPUA 1RM1A 1MPGA 3ENOC 4ROCB 2PWWA 1B9KA 2Z0FA 1YQMA 2NWVA 1UT4A 2DKAA 5AN4A 1CDWA 2EHBD 2MJ7A 3PDKA 1R4XA 3KRMA 3OCIA 2NOEA 2IV8A 5JN5A 1QN3A 2NOHA 1WQAA 4TPSA 2D0CA 2JHJA 1EUVA 2QRDA 3VN5A 2V9JA 3UW2A 2F7LA 2VJ0A 3F10A 3F0ZA 4WX8A 4EALA 1KO9A 2Z8UA 2JHNA 1KY6A 1W80A 1JFIC 1C4GA 2QRCA 4EAIA 4EAKA 3I3WA 4EAGA 3EAYA 1KYDA 3OH9A 2JOIA 3EIKA 2V8QA 3ULXA 2D0BA 1PVSA 1PCJX 3ENCA 2FGTA 1TBPA 1QNAA 2D0AA 1V5SA 2YH5A 3D4VA 1YQLA 1TUOA 4WZSD 1QN9A 3HS8A 1YTFA 4I8OA 3PMGA 1P5DX 1VTLE 4RODB 3D7QA 2NOZA 2G30A 3CWUA 1FN7A 1KFQA 4EJZA 1YQKA 2HZSA 1N39A 2JPIA 2QLVA 2R5XA 1LWVA 3CWAA 1DIZA 1JDYA 2LAEA 3TDHA 3SNSA 1PCMX 1M5Q1 4EAJA 1M3HA 1QN8A 2NOLA 1E42A 3HS9A 5BMPA 1QNBA 1QTSA 3BKQX 3OH6A 2ZFDB 3H1ZA 4IL8A 2DKDA 2H4LX 1YTBA 2I5WA 3OLPA 5IYBP 3CWTA 3CWSA 1M3QA 1QN7A 1NGMA 3CVTA 1LWWA 1EBMA 5KL0A 1QN4A 2FUVA 2Y8LA 1LWYA 1C9BB 2NOBA 2HL9A 2FKFA 2DKCA 2OOXA 1J3MA 4BJUA 3OSTA 1QN6A 4CFFA 1TGHA 2HL8A 4EJYA 2HKPA 2QREA 1VOKA 1T6AA 1TBAB 1QNCA 3OSEA 3OC3C 2NVMA 2NOIA 1N3CA 1P5GX 1AISA 4MRQA 1WJWA 3I0XA 3I0WA 3TE5A 2XHIA 4B0AA 1KYFA 3OSMA 5IYCP 4DULA 1LXTA 3ASMA 2OOYA 3IH7A 1VTOA 1NH2A 1HU0A 5IYDP 1PCZA 1KY7A 2Y8QA 3N89A 3T4NA 1KYUA 1VOLB 1C47A 4WXAA 3RPJA 2MZ8A 2FKMX 2NLVA 4D7RA 1D3UA 3NA5A 2O3OA 4Q11A 3OGDA 1YQRA 4QG5A 2YA3A 4C7PA 2QR1A 1QN5A 2NOFA 1UL7A 1PZDA 1QNEA 2IV9A 1NVPA 5EPCA 5JMVD 1VKLA 3DPTA 3RSMA 1K2YX 2HZMA 4HJHA 4D7QA 1MP9A 1Q9UA 1XSZA 3C04A 1QTPA 5BMNA 1KFIA 1N3AA 1K35A 2H5AX 1UT7A 4ROEB 4PY5A
chains in the Genus database with same CATH topology
3TE5A 2V8QA 2V92A 1V5SA 2OOYA 2Y8QA 3T4NA 2EHBD 2Y8LA 2QRDA 2YA3A 2QR1A 2V9JA 2OOXA 1UL7A 2QLVA 4CFFA 2QREA 4EALA 3OSEA 3TDHA 2QRCA 4EAIA 4EAKA 4EAJA 4EAGA 2ZFDB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TE5 A;  2V8Q A;  2V92 A;  1V5S A;  2OOY A;  2Y8Q A;  3T4N A;  2EHB D;  2Y8L A;  2QRD A;  2YA3 A;  2QR1 A;  2V9J A;  2OOX A;  1UL7 A;  2QLV A;  4CFF A;  2QRE A;  4EAL A;  3OSE A;  3TDH A;  2QRC A;  4EAI A;  4EAK A;  4EAJ A;  4EAG A;  2ZFD B; 
#chains in the Genus database with same CATH topology
 3KTU A;  5HSH A;  3CW7 A;  3CVS A;  5F9C A;  2V92 A;  3DPU A;  1RM1 A;  1MPG A;  3ENO C;  4ROC B;  2PWW A;  1B9K A;  2Z0F A;  1YQM A;  2NWV A;  1UT4 A;  2DKA A;  5AN4 A;  1CDW A;  2EHB D;  2MJ7 A;  3PDK A;  1R4X A;  3KRM A;  3OCI A;  2NOE A;  2IV8 A;  5JN5 A;  1QN3 A;  2NOH A;  1WQA A;  4TPS A;  2D0C A;  2JHJ A;  1EUV A;  2QRD A;  3VN5 A;  2V9J A;  3UW2 A;  2F7L A;  2VJ0 A;  3F10 A;  3F0Z A;  4WX8 A;  4EAL A;  1KO9 A;  2Z8U A;  2JHN A;  1KY6 A;  1W80 A;  1JFI C;  1C4G A;  2QRC A;  4EAI A;  4EAK A;  3I3W A;  4EAG A;  3EAY A;  1KYD A;  3OH9 A;  2JOI A;  3EIK A;  2V8Q A;  3ULX A;  2D0B A;  1PVS A;  1PCJ X;  3ENC A;  2FGT A;  1TBP A;  1QNA A;  2D0A A;  1V5S A;  2YH5 A;  3D4V A;  1YQL A;  1TUO A;  4WZS D;  1QN9 A;  3HS8 A;  1YTF A;  4I8O A;  3PMG A;  1P5D X;  1VTL E;  4ROD B;  3D7Q A;  2NOZ A;  2G30 A;  3CWU A;  1FN7 A;  1KFQ A;  4EJZ A;  1YQK A;  2HZS A;  1N39 A;  2JPI A;  2QLV A;  2R5X A;  1LWV A;  3CWA A;  1DIZ A;  1JDY A;  2LAE A;  3TDH A;  3SNS A;  1PCM X;  1M5Q 1;  4EAJ A;  1M3H A;  1QN8 A;  2NOL A;  1E42 A;  3HS9 A;  5BMP A;  1QNB A;  1QTS A;  3BKQ X;  3OH6 A;  2ZFD B;  3H1Z A;  4IL8 A;  2DKD A;  2H4L X;  1YTB A;  2I5W A;  3OLP A;  5IYB P;  3CWT A;  3CWS A;  1M3Q A;  1QN7 A;  1NGM A;  3CVT A;  1LWW A;  1EBM A;  5KL0 A;  1QN4 A;  2FUV A;  2Y8L A;  1LWY A;  1C9B B;  2NOB A;  2HL9 A;  2FKF A;  2DKC A;  2OOX A;  1J3M A;  4BJU A;  3OST A;  1QN6 A;  4CFF A;  1TGH A;  2HL8 A;  4EJY A;  2HKP A;  2QRE A;  1VOK A;  1T6A A;  1TBA B;  1QNC A;  3OSE A;  3OC3 C;  2NVM A;  2NOI A;  1N3C A;  1P5G X;  1AIS A;  4MRQ A;  1WJW A;  3I0X A;  3I0W A;  3TE5 A;  2XHI A;  4B0A A;  1KYF A;  3OSM A;  5IYC P;  4DUL A;  1LXT A;  3ASM A;  2OOY A;  3IH7 A;  1VTO A;  1NH2 A;  1HU0 A;  5IYD P;  1PCZ A;  1KY7 A;  2Y8Q A;  3N89 A;  3T4N A;  1KYU A;  1VOL B;  1C47 A;  4WXA A;  3RPJ A;  2MZ8 A;  2FKM X;  2NLV A;  4D7R A;  1D3U A;  3NA5 A;  2O3O A;  4Q11 A;  3OGD A;  1YQR A;  4QG5 A;  2YA3 A;  4C7P A;  2QR1 A;  1QN5 A;  2NOF A;  1UL7 A;  1PZD A;  1QNE A;  2IV9 A;  1NVP A;  5EPC A;  5JMV D;  1VKL A;  3DPT A;  3RSM A;  1K2Y X;  2HZM A;  4HJH A;  4D7Q A;  1MP9 A;  1Q9U A;  1XSZ A;  3C04 A;  1QTP A;  5BMN A;  1KFI A;  1N3A A;  1K35 A;  2H5A X;  1UT7 A;  4ROE B;  4PY5 A; 
#chains in the Genus database with same CATH homology
 3TE5 A;  2V8Q A;  2V92 A;  1V5S A;  2OOY A;  2Y8Q A;  3T4N A;  2EHB D;  2Y8L A;  2QRD A;  2YA3 A;  2QR1 A;  2V9J A;  2OOX A;  1UL7 A;  2QLV A;  4CFF A;  2QRE A;  4EAL A;  3OSE A;  3TDH A;  2QRC A;  4EAI A;  4EAK A;  4EAJ A;  4EAG A;  2ZFD B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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