2V92A

Crystal structure of the regulatory fragment of mammalian ampk in complexes with atp-amp
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
156
structure length
102
Chain Sequence
SMAWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDEVAPRPGSHTIEFFEMCANLIKILAQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1
total genus 21
structure length 102
sequence length 156
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-08-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2v92A01
4EALA 3T4NA 2Y8QA 4CFFA 2QR1A 2V8QA 2YA3A 2QREA 1V5SA 2V92A 4EAJA 2V9JA 2OOXA 2Y8LA 2ZFDB 2QRCA 2EHBD 4EAGA 4EAIA 3OSEA 2QLVA 2QRDA 1UL7A 4EAKA 3TDHA 2OOYA 3TE5A
chains in the Genus database with same CATH superfamily
1PVSA 2F7LA 3HS8A 5IYCP 4PY5A 4DULA 2HL9A 2PWWA 2NWVA 3OSMA 4WX8A 1HU0A 3ENOC 2NOHA 5JMVD 1WQAA 1TUOA 1TGHA 2DKAA 1AISA 1V5SA 3UW2A 1LWVA 2V92A 1M3QA 4EAJA 1VOLB 3H1ZA 4I8OA 4IL8A 3I0WA 1QTSA 2Z8UA 3I0XA 4D7RA 3CWTA 2HL8A 2EHBD 4EJZA 4TPSA 3I3WA 1UT7A 1QN8A 2NOEA 2O3OA 1UL7A 1YQRA 1XSZA 1NH2A 3CWAA 1C47A 1KY7A 3D4VA 1QNEA 3TE5A 2XHIA 4WXAA 3F10A 1YQMA 4EALA 1QNAA 1EUVA 1P5GX 3T4NA 5F9CA 1NVPA 2Y8QA 1N3AA 3PMGA 1KYFA 3CVTA 1QN5A 3C04A 3PDKA 2JHNA 2HKPA 2QR1A 3ASMA 1MP9A 3IH7A 1P5DX 2H5AX 3OCIA 2YA3A 3OH6A 1FN7A 1EBMA 2NOZA 1DIZA 2NOIA 1K35A 1PCZA 1LWWA 1QN9A 2Z0FA 3D7QA 2NOLA 2IV9A 2OOXA 2Y8LA 2ZFDB 2QRCA 4Q11A 3VN5A 5IYBP 3N89A 5JN5A 1J3MA 2QLVA 1B9KA 3EAYA 4EAKA 2JPIA 3TDHA 3OC3C 2I5WA 1PZDA 4ROCB 1Q9UA 3ULXA 1YTBA 4C7PA 1KFQA 3RPJA 3OGDA 3OLPA 1TBAB 2FKFA 1WJWA 4EJYA 4ROEB 1UT4A 2NOFA 2R5XA 2DKDA 3CWUA 1JFIC 1C4GA 2YH5A 5AN4A 4QG5A 1M5Q1 2D0CA 1T6AA 3F0ZA 1N3CA 1RM1A 3DPTA 1W80A 1QNCA 1QNBA 2V9JA 3EIKA 4EAGA 2MZ8A 2FKMX 4EAIA 3OSEA 3OH9A 1NGMA 1D3UA 3KRMA 1PCMX 2QRDA 4WZSD 1M3HA 1QN3A 3SNSA 1VTLE 3OSTA 1E42A 4MRQA 1YTFA 2OOYA 2NLVA 2IV8A 1K2YX 1LWYA 3ENCA 1KYUA 3BKQX 5KL0A 1N39A 1QN4A 2FGTA 1YQKA 4D7QA 2NOBA 1LXTA 1MPGA 2D0AA 4RODB 1R4XA 1KY6A 2VJ0A 5BMNA 1CDWA 4CFFA 2LAEA 3CWSA 2H4LX 2V8QA 2DKCA 3DPUA 5EPCA 1TBPA 3CW7A 3KTUA 2NVMA 1JDYA 2QREA 3CVSA 1VOKA 2FUVA 4HJHA 1KFIA 4BJUA 2JHJA 1VTOA 1KYDA 1VKLA 1QN7A 2HZMA 2MJ7A 1QN6A 1PCJX 3NA5A 1YQLA 2G30A 2JOIA 5IYDP 4B0AA 5HSHA 2D0BA 1KO9A 3HS9A 2HZSA 5BMPA 1C9BB 1QTPA 3RSMA
chains in the Genus database with same CATH topology
4EALA 3T4NA 2Y8QA 4CFFA 2QR1A 2V8QA 2YA3A 2QREA 1V5SA 2V92A 4EAJA 2V9JA 2OOXA 2Y8LA 2ZFDB 2QRCA 2EHBD 4EAGA 4EAIA 3OSEA 2QLVA 2QRDA 1UL7A 4EAKA 3TDHA 2OOYA 3TE5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EAL A;  3T4N A;  2Y8Q A;  4CFF A;  2QR1 A;  2V8Q A;  2YA3 A;  2QRE A;  1V5S A;  2V92 A;  4EAJ A;  2V9J A;  2OOX A;  2Y8L A;  2ZFD B;  2QRC A;  2EHB D;  4EAG A;  4EAI A;  3OSE A;  2QLV A;  2QRD A;  1UL7 A;  4EAK A;  3TDH A;  2OOY A;  3TE5 A; 
#chains in the Genus database with same CATH topology
 1PVS A;  2F7L A;  3HS8 A;  5IYC P;  4PY5 A;  4DUL A;  2HL9 A;  2PWW A;  2NWV A;  3OSM A;  4WX8 A;  1HU0 A;  3ENO C;  2NOH A;  5JMV D;  1WQA A;  1TUO A;  1TGH A;  2DKA A;  1AIS A;  1V5S A;  3UW2 A;  1LWV A;  2V92 A;  1M3Q A;  4EAJ A;  1VOL B;  3H1Z A;  4I8O A;  4IL8 A;  3I0W A;  1QTS A;  2Z8U A;  3I0X A;  4D7R A;  3CWT A;  2HL8 A;  2EHB D;  4EJZ A;  4TPS A;  3I3W A;  1UT7 A;  1QN8 A;  2NOE A;  2O3O A;  1UL7 A;  1YQR A;  1XSZ A;  1NH2 A;  3CWA A;  1C47 A;  1KY7 A;  3D4V A;  1QNE A;  3TE5 A;  2XHI A;  4WXA A;  3F10 A;  1YQM A;  4EAL A;  1QNA A;  1EUV A;  1P5G X;  3T4N A;  5F9C A;  1NVP A;  2Y8Q A;  1N3A A;  3PMG A;  1KYF A;  3CVT A;  1QN5 A;  3C04 A;  3PDK A;  2JHN A;  2HKP A;  2QR1 A;  3ASM A;  1MP9 A;  3IH7 A;  1P5D X;  2H5A X;  3OCI A;  2YA3 A;  3OH6 A;  1FN7 A;  1EBM A;  2NOZ A;  1DIZ A;  2NOI A;  1K35 A;  1PCZ A;  1LWW A;  1QN9 A;  2Z0F A;  3D7Q A;  2NOL A;  2IV9 A;  2OOX A;  2Y8L A;  2ZFD B;  2QRC A;  4Q11 A;  3VN5 A;  5IYB P;  3N89 A;  5JN5 A;  1J3M A;  2QLV A;  1B9K A;  3EAY A;  4EAK A;  2JPI A;  3TDH A;  3OC3 C;  2I5W A;  1PZD A;  4ROC B;  1Q9U A;  3ULX A;  1YTB A;  4C7P A;  1KFQ A;  3RPJ A;  3OGD A;  3OLP A;  1TBA B;  2FKF A;  1WJW A;  4EJY A;  4ROE B;  1UT4 A;  2NOF A;  2R5X A;  2DKD A;  3CWU A;  1JFI C;  1C4G A;  2YH5 A;  5AN4 A;  4QG5 A;  1M5Q 1;  2D0C A;  1T6A A;  3F0Z A;  1N3C A;  1RM1 A;  3DPT A;  1W80 A;  1QNC A;  1QNB A;  2V9J A;  3EIK A;  4EAG A;  2MZ8 A;  2FKM X;  4EAI A;  3OSE A;  3OH9 A;  1NGM A;  1D3U A;  3KRM A;  1PCM X;  2QRD A;  4WZS D;  1M3H A;  1QN3 A;  3SNS A;  1VTL E;  3OST A;  1E42 A;  4MRQ A;  1YTF A;  2OOY A;  2NLV A;  2IV8 A;  1K2Y X;  1LWY A;  3ENC A;  1KYU A;  3BKQ X;  5KL0 A;  1N39 A;  1QN4 A;  2FGT A;  1YQK A;  4D7Q A;  2NOB A;  1LXT A;  1MPG A;  2D0A A;  4ROD B;  1R4X A;  1KY6 A;  2VJ0 A;  5BMN A;  1CDW A;  4CFF A;  2LAE A;  3CWS A;  2H4L X;  2V8Q A;  2DKC A;  3DPU A;  5EPC A;  1TBP A;  3CW7 A;  3KTU A;  2NVM A;  1JDY A;  2QRE A;  3CVS A;  1VOK A;  2FUV A;  4HJH A;  1KFI A;  4BJU A;  2JHJ A;  1VTO A;  1KYD A;  1VKL A;  1QN7 A;  2HZM A;  2MJ7 A;  1QN6 A;  1PCJ X;  3NA5 A;  1YQL A;  2G30 A;  2JOI A;  5IYD P;  4B0A A;  5HSH A;  2D0B A;  1KO9 A;  3HS9 A;  2HZS A;  5BMP A;  1C9B B;  1QTP A;  3RSM A; 
#chains in the Genus database with same CATH homology
 4EAL A;  3T4N A;  2Y8Q A;  4CFF A;  2QR1 A;  2V8Q A;  2YA3 A;  2QRE A;  1V5S A;  2V92 A;  4EAJ A;  2V9J A;  2OOX A;  2Y8L A;  2ZFD B;  2QRC A;  2EHB D;  4EAG A;  4EAI A;  3OSE A;  2QLV A;  2QRD A;  1UL7 A;  4EAK A;  3TDH A;  2OOY A;  3TE5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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