2V9JA

Crystal structure of the regulatory fragment of mammalian ampk in complexes with mg.atp-amp
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
156
structure length
102
Chain Sequence
SMAWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDEVAPRPGSHTIEFFEMCANLIKILAQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1
total genus 23
structure length 102
sequence length 156
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2007-08-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2v9jA01
1V5SA 3TDHA 4EAGA 2EHBD 2QREA 2QR1A 3OSEA 4EAIA 1UL7A 2Y8LA 2ZFDB 2QRCA 2V92A 4EALA 2YA3A 4EAKA 2V9JA 4EAJA 2OOYA 2QRDA 2V8QA 2QLVA 2Y8QA 4CFFA 3TE5A 3T4NA 2OOXA
chains in the Genus database with same CATH superfamily
3OLPA 1RM1A 2EHBD 1KY7A 1PZDA 3EAYA 4C7PA 4EAIA 1KFQA 2G30A 3RPJA 3N89A 3UW2A 3I0WA 1YQLA 1P5GX 1QNBA 1B9KA 3NA5A 1UT7A 2Y8LA 1CDWA 2D0CA 1J3MA 3VN5A 1QN7A 2V92A 4EALA 3CWSA 5BMPA 1VOLB 3ASMA 1YTFA 1JFIC 3BKQX 1FN7A 4EAJA 2JHNA 2OOYA 3CWUA 1LWWA 1WJWA 1QNCA 3CWAA 5JMVD 1XSZA 4CFFA 2NWVA 3I3WA 4QG5A 3TE5A 1UT4A 3ULXA 4I8OA 1QN9A 1W80A 1LXTA 3TDHA 4WXAA 2O3OA 1YTBA 1AISA 4EJZA 1N3AA 2YH5A 2MJ7A 3PDKA 1Q9UA 2JPIA 1NGMA 4B0AA 4D7QA 3H1ZA 3ENCA 2ZFDB 3HS8A 2OOXA 1YQKA 1QNEA 2Z0FA 1N39A 1PCZA 5BMNA 5IYBP 3IH7A 1JDYA 2FKFA 1E42A 2NLVA 1VKLA 2PWWA 3EIKA 3KRMA 1YQRA 2XHIA 1LWVA 1KY6A 2V8QA 1K2YX 2Y8QA 4EJYA 3OSTA 3ENOC 1R4XA 1YQMA 3T4NA 1KO9A 1KYDA 2FUVA 2Z8UA 1V5SA 1QN5A 4DULA 3F0ZA 2DKAA 1HU0A 3RSMA 3OH9A 2QR1A 4PY5A 3OSEA 5JN5A 2NVMA 3CVTA 2NOHA 5KL0A 4Q11A 5IYCP 2NOEA 2MZ8A 4HJHA 1N3CA 3OSMA 3CW7A 1C9BB 1DIZA 2IV8A 3OCIA 4IL8A 3I0XA 1QNAA 2JOIA 1QN3A 1D3UA 1QTPA 2YA3A 1VTOA 5IYDP 1KYUA 4ROCB 1QTSA 5EPCA 2V9JA 4RODB 1QN8A 2FGTA 3DPTA 4TPSA 2HL9A 1PVSA 2QLVA 3CVSA 2F7LA 2I5WA 2R5XA 2IV9A 3CWTA 2NOZA 2NOLA 2QRDA 4BJUA 2H4LX 1LWYA 1WQAA 4EAGA 5F9CA 3OH6A 1KFIA 2QREA 1KYFA 1VOKA 4ROEB 1P5DX 1TBPA 1M3HA 2HL8A 2FKMX 2HZSA 2JHJA 5HSHA 1NH2A 1QN6A 3HS9A 3OGDA 1VTLE 1M3QA 1K35A 1UL7A 2HKPA 1NVPA 1T6AA 2LAEA 3SNSA 1TBAB 1EBMA 2QRCA 2NOIA 4WX8A 3C04A 4MRQA 1TGHA 4D7RA 3D7QA 2NOBA 4WZSD 4EAKA 1PCJX 3F10A 2D0AA 2DKDA 3D4VA 1MP9A 1EUVA 3KTUA 2H5AX 1QN4A 3OC3C 1M5Q1 1PCMX 2DKCA 2HZMA 2VJ0A 3PMGA 1C4GA 1TUOA 3DPUA 5AN4A 2NOFA 2D0BA 1C47A 1MPGA
chains in the Genus database with same CATH topology
1V5SA 3TDHA 4EAGA 2EHBD 2QREA 2QR1A 3OSEA 4EAIA 1UL7A 2Y8LA 2ZFDB 2QRCA 2V92A 4EALA 2YA3A 4EAKA 2V9JA 4EAJA 2OOYA 2QRDA 2V8QA 2QLVA 2Y8QA 4CFFA 3TE5A 3T4NA 2OOXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1V5S A;  3TDH A;  4EAG A;  2EHB D;  2QRE A;  2QR1 A;  3OSE A;  4EAI A;  1UL7 A;  2Y8L A;  2ZFD B;  2QRC A;  2V92 A;  4EAL A;  2YA3 A;  4EAK A;  2V9J A;  4EAJ A;  2OOY A;  2QRD A;  2V8Q A;  2QLV A;  2Y8Q A;  4CFF A;  3TE5 A;  3T4N A;  2OOX A; 
#chains in the Genus database with same CATH topology
 3OLP A;  1RM1 A;  2EHB D;  1KY7 A;  1PZD A;  3EAY A;  4C7P A;  4EAI A;  1KFQ A;  2G30 A;  3RPJ A;  3N89 A;  3UW2 A;  3I0W A;  1YQL A;  1P5G X;  1QNB A;  1B9K A;  3NA5 A;  1UT7 A;  2Y8L A;  1CDW A;  2D0C A;  1J3M A;  3VN5 A;  1QN7 A;  2V92 A;  4EAL A;  3CWS A;  5BMP A;  1VOL B;  3ASM A;  1YTF A;  1JFI C;  3BKQ X;  1FN7 A;  4EAJ A;  2JHN A;  2OOY A;  3CWU A;  1LWW A;  1WJW A;  1QNC A;  3CWA A;  5JMV D;  1XSZ A;  4CFF A;  2NWV A;  3I3W A;  4QG5 A;  3TE5 A;  1UT4 A;  3ULX A;  4I8O A;  1QN9 A;  1W80 A;  1LXT A;  3TDH A;  4WXA A;  2O3O A;  1YTB A;  1AIS A;  4EJZ A;  1N3A A;  2YH5 A;  2MJ7 A;  3PDK A;  1Q9U A;  2JPI A;  1NGM A;  4B0A A;  4D7Q A;  3H1Z A;  3ENC A;  2ZFD B;  3HS8 A;  2OOX A;  1YQK A;  1QNE A;  2Z0F A;  1N39 A;  1PCZ A;  5BMN A;  5IYB P;  3IH7 A;  1JDY A;  2FKF A;  1E42 A;  2NLV A;  1VKL A;  2PWW A;  3EIK A;  3KRM A;  1YQR A;  2XHI A;  1LWV A;  1KY6 A;  2V8Q A;  1K2Y X;  2Y8Q A;  4EJY A;  3OST A;  3ENO C;  1R4X A;  1YQM A;  3T4N A;  1KO9 A;  1KYD A;  2FUV A;  2Z8U A;  1V5S A;  1QN5 A;  4DUL A;  3F0Z A;  2DKA A;  1HU0 A;  3RSM A;  3OH9 A;  2QR1 A;  4PY5 A;  3OSE A;  5JN5 A;  2NVM A;  3CVT A;  2NOH A;  5KL0 A;  4Q11 A;  5IYC P;  2NOE A;  2MZ8 A;  4HJH A;  1N3C A;  3OSM A;  3CW7 A;  1C9B B;  1DIZ A;  2IV8 A;  3OCI A;  4IL8 A;  3I0X A;  1QNA A;  2JOI A;  1QN3 A;  1D3U A;  1QTP A;  2YA3 A;  1VTO A;  5IYD P;  1KYU A;  4ROC B;  1QTS A;  5EPC A;  2V9J A;  4ROD B;  1QN8 A;  2FGT A;  3DPT A;  4TPS A;  2HL9 A;  1PVS A;  2QLV A;  3CVS A;  2F7L A;  2I5W A;  2R5X A;  2IV9 A;  3CWT A;  2NOZ A;  2NOL A;  2QRD A;  4BJU A;  2H4L X;  1LWY A;  1WQA A;  4EAG A;  5F9C A;  3OH6 A;  1KFI A;  2QRE A;  1KYF A;  1VOK A;  4ROE B;  1P5D X;  1TBP A;  1M3H A;  2HL8 A;  2FKM X;  2HZS A;  2JHJ A;  5HSH A;  1NH2 A;  1QN6 A;  3HS9 A;  3OGD A;  1VTL E;  1M3Q A;  1K35 A;  1UL7 A;  2HKP A;  1NVP A;  1T6A A;  2LAE A;  3SNS A;  1TBA B;  1EBM A;  2QRC A;  2NOI A;  4WX8 A;  3C04 A;  4MRQ A;  1TGH A;  4D7R A;  3D7Q A;  2NOB A;  4WZS D;  4EAK A;  1PCJ X;  3F10 A;  2D0A A;  2DKD A;  3D4V A;  1MP9 A;  1EUV A;  3KTU A;  2H5A X;  1QN4 A;  3OC3 C;  1M5Q 1;  1PCM X;  2DKC A;  2HZM A;  2VJ0 A;  3PMG A;  1C4G A;  1TUO A;  3DPU A;  5AN4 A;  2NOF A;  2D0B A;  1C47 A;  1MPG A; 
#chains in the Genus database with same CATH homology
 1V5S A;  3TDH A;  4EAG A;  2EHB D;  2QRE A;  2QR1 A;  3OSE A;  4EAI A;  1UL7 A;  2Y8L A;  2ZFD B;  2QRC A;  2V92 A;  4EAL A;  2YA3 A;  4EAK A;  2V9J A;  4EAJ A;  2OOY A;  2QRD A;  2V8Q A;  2QLV A;  2Y8Q A;  4CFF A;  3TE5 A;  3T4N A;  2OOX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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