2Y8LA

Structure of the regulatory fragment of mammalian ampk in complex with two adp
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
158
structure length
104
Chain Sequence
SMAWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDEVAPRPGSHTIEFFEMCANLIKNSCTVN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of Mammalian Ampk and its Regulation by Adp
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1
total genus 25
structure length 104
sequence length 158
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2011-02-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2y8lA01
2OOYA 2QRDA 4EAIA 4EAGA 3OSEA 4EAKA 4CFFA 2QREA 3TE5A 2V92A 2OOXA 4EAJA 2QR1A 2V9JA 3T4NA 2Y8LA 2QRCA 2EHBD 3TDHA 2Y8QA 2V8QA 4EALA 2YA3A 1UL7A 2QLVA 1V5SA 2ZFDB
chains in the Genus database with same CATH superfamily
1JDYA 1FN7A 1YTFA 1C4GA 2O3OA 5JN5A 2NOBA 2D0CA 1KYDA 1KY6A 1C47A 1N39A 1C9BB 4EAKA 3DPUA 2F7LA 4CFFA 2LAEA 1QN7A 2QREA 3OGDA 1TBPA 1N3CA 3UW2A 2FKMX 4DULA 4EAJA 2MZ8A 2V9JA 3D4VA 1QN8A 5KL0A 2EHBD 3H1ZA 2I5WA 1CDWA 3I0XA 1PCJX 2D0AA 1M3QA 3HS9A 3NA5A 2NOHA 1M5Q1 1M3HA 2V8QA 4EJYA 3I0WA 4EALA 1EBMA 1WJWA 3CVTA 2NOFA 1QNBA 2NVMA 1UL7A 3KRMA 1VKLA 1TUOA 1LXTA 5HSHA 1MP9A 1TBAB 2VJ0A 2ZFDB 2OOYA 2DKCA 3PDKA 2D0BA 4B0AA 4PY5A 1QN5A 1B9KA 1WQAA 2DKAA 2HL8A 5EPCA 3EAYA 4C7PA 4EAIA 3RPJA 1VTOA 2NOEA 4HJHA 5IYCP 4ROEB 2HL9A 4BJUA 1KYUA 2DKDA 2JHNA 2JHJA 2PWWA 4RODB 1NGMA 1UT4A 3OCIA 1VOLB 4MRQA 1PCZA 1LWWA 3CWSA 2QR1A 2Y8LA 2QRCA 2Z0FA 2G30A 4ROCB 5BMNA 2IV9A 1VTLE 2NLVA 1UT7A 4WX8A 2JOIA 3OC3C 1J3MA 2NOIA 4WXAA 3VN5A 1R4XA 2IV8A 2HZSA 2R5XA 1QN6A 1TGHA 1PZDA 2MJ7A 3OSMA 3BKQX 3ENOC 3CW7A 1LWVA 4EJZA 1K2YX 1HU0A 4D7RA 1KO9A 3DPTA 1LWYA 1XSZA 5F9CA 1RM1A 1NVPA 1QNEA 3RSMA 2NOZA 3C04A 3CWUA 3OSTA 2FKFA 3HS8A 1QNCA 4D7QA 3PMGA 1YTBA 1VOKA 1QTPA 3ASMA 3ULXA 2OOXA 5JMVD 3SNSA 4QG5A 1QN4A 1NH2A 2HKPA 2NWVA 3F10A 1YQLA 1KY7A 3TDHA 1DIZA 3EIKA 5AN4A 4IL8A 1AISA 1PVSA 1KYFA 1EUVA 1MPGA 1T6AA 3KTUA 1KFIA 2FUVA 3N89A 1KFQA 3OLPA 1QTSA 1YQMA 1QNAA 2QLVA 1V5SA 5IYDP 3D7QA 3F0ZA 1QN9A 3IH7A 4I8OA 2QRDA 2NOLA 2JPIA 1N3AA 1E42A 4EAGA 1K35A 3OSEA 1YQKA 1W80A 2H5AX 1YQRA 3TE5A 4Q11A 2V92A 3OH6A 2HZMA 5IYBP 2H4LX 3OH9A 2Z8UA 3T4NA 3CVSA 3CWAA 1JFIC 3I3WA 2XHIA 4TPSA 2YH5A 1PCMX 2Y8QA 1QN3A 1Q9UA 5BMPA 1D3UA 1P5GX 2YA3A 4WZSD 3CWTA 2FGTA 3ENCA 1P5DX
chains in the Genus database with same CATH topology
2OOYA 2QRDA 4EAIA 4EAGA 3OSEA 4EAKA 4CFFA 2QREA 3TE5A 2V92A 2OOXA 4EAJA 2QR1A 2V9JA 3T4NA 2Y8LA 2QRCA 2EHBD 3TDHA 2Y8QA 2V8QA 4EALA 2YA3A 1UL7A 2QLVA 1V5SA 2ZFDB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OOY A;  2QRD A;  4EAI A;  4EAG A;  3OSE A;  4EAK A;  4CFF A;  2QRE A;  3TE5 A;  2V92 A;  2OOX A;  4EAJ A;  2QR1 A;  2V9J A;  3T4N A;  2Y8L A;  2QRC A;  2EHB D;  3TDH A;  2Y8Q A;  2V8Q A;  4EAL A;  2YA3 A;  1UL7 A;  2QLV A;  1V5S A;  2ZFD B; 
#chains in the Genus database with same CATH topology
 1JDY A;  1FN7 A;  1YTF A;  1C4G A;  2O3O A;  5JN5 A;  2NOB A;  2D0C A;  1KYD A;  1KY6 A;  1C47 A;  1N39 A;  1C9B B;  4EAK A;  3DPU A;  2F7L A;  4CFF A;  2LAE A;  1QN7 A;  2QRE A;  3OGD A;  1TBP A;  1N3C A;  3UW2 A;  2FKM X;  4DUL A;  4EAJ A;  2MZ8 A;  2V9J A;  3D4V A;  1QN8 A;  5KL0 A;  2EHB D;  3H1Z A;  2I5W A;  1CDW A;  3I0X A;  1PCJ X;  2D0A A;  1M3Q A;  3HS9 A;  3NA5 A;  2NOH A;  1M5Q 1;  1M3H A;  2V8Q A;  4EJY A;  3I0W A;  4EAL A;  1EBM A;  1WJW A;  3CVT A;  2NOF A;  1QNB A;  2NVM A;  1UL7 A;  3KRM A;  1VKL A;  1TUO A;  1LXT A;  5HSH A;  1MP9 A;  1TBA B;  2VJ0 A;  2ZFD B;  2OOY A;  2DKC A;  3PDK A;  2D0B A;  4B0A A;  4PY5 A;  1QN5 A;  1B9K A;  1WQA A;  2DKA A;  2HL8 A;  5EPC A;  3EAY A;  4C7P A;  4EAI A;  3RPJ A;  1VTO A;  2NOE A;  4HJH A;  5IYC P;  4ROE B;  2HL9 A;  4BJU A;  1KYU A;  2DKD A;  2JHN A;  2JHJ A;  2PWW A;  4ROD B;  1NGM A;  1UT4 A;  3OCI A;  1VOL B;  4MRQ A;  1PCZ A;  1LWW A;  3CWS A;  2QR1 A;  2Y8L A;  2QRC A;  2Z0F A;  2G30 A;  4ROC B;  5BMN A;  2IV9 A;  1VTL E;  2NLV A;  1UT7 A;  4WX8 A;  2JOI A;  3OC3 C;  1J3M A;  2NOI A;  4WXA A;  3VN5 A;  1R4X A;  2IV8 A;  2HZS A;  2R5X A;  1QN6 A;  1TGH A;  1PZD A;  2MJ7 A;  3OSM A;  3BKQ X;  3ENO C;  3CW7 A;  1LWV A;  4EJZ A;  1K2Y X;  1HU0 A;  4D7R A;  1KO9 A;  3DPT A;  1LWY A;  1XSZ A;  5F9C A;  1RM1 A;  1NVP A;  1QNE A;  3RSM A;  2NOZ A;  3C04 A;  3CWU A;  3OST A;  2FKF A;  3HS8 A;  1QNC A;  4D7Q A;  3PMG A;  1YTB A;  1VOK A;  1QTP A;  3ASM A;  3ULX A;  2OOX A;  5JMV D;  3SNS A;  4QG5 A;  1QN4 A;  1NH2 A;  2HKP A;  2NWV A;  3F10 A;  1YQL A;  1KY7 A;  3TDH A;  1DIZ A;  3EIK A;  5AN4 A;  4IL8 A;  1AIS A;  1PVS A;  1KYF A;  1EUV A;  1MPG A;  1T6A A;  3KTU A;  1KFI A;  2FUV A;  3N89 A;  1KFQ A;  3OLP A;  1QTS A;  1YQM A;  1QNA A;  2QLV A;  1V5S A;  5IYD P;  3D7Q A;  3F0Z A;  1QN9 A;  3IH7 A;  4I8O A;  2QRD A;  2NOL A;  2JPI A;  1N3A A;  1E42 A;  4EAG A;  1K35 A;  3OSE A;  1YQK A;  1W80 A;  2H5A X;  1YQR A;  3TE5 A;  4Q11 A;  2V92 A;  3OH6 A;  2HZM A;  5IYB P;  2H4L X;  3OH9 A;  2Z8U A;  3T4N A;  3CVS A;  3CWA A;  1JFI C;  3I3W A;  2XHI A;  4TPS A;  2YH5 A;  1PCM X;  2Y8Q A;  1QN3 A;  1Q9U A;  5BMP A;  1D3U A;  1P5G X;  2YA3 A;  4WZS D;  3CWT A;  2FGT A;  3ENC A;  1P5D X; 
#chains in the Genus database with same CATH homology
 2OOY A;  2QRD A;  4EAI A;  4EAG A;  3OSE A;  4EAK A;  4CFF A;  2QRE A;  3TE5 A;  2V92 A;  2OOX A;  4EAJ A;  2QR1 A;  2V9J A;  3T4N A;  2Y8L A;  2QRC A;  2EHB D;  3TDH A;  2Y8Q A;  2V8Q A;  4EAL A;  2YA3 A;  1UL7 A;  2QLV A;  1V5S A;  2ZFD B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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