2Y8QA

Structure of the regulatory fragment of mammalian ampk in complex with one adp
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
158
structure length
104
Chain Sequence
SMAWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDEVAPRPGSHTIEFFEMCANLIKNSCTVN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of Mammalian Ampk and its Regulation by Adp
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1
total genus 23
structure length 104
sequence length 158
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2011-02-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2y8qA01
3TE5A 4EAIA 4EALA 2OOXA 1UL7A 2QR1A 4EAJA 2V8QA 2OOYA 2V92A 2Y8LA 2V9JA 4CFFA 2QRCA 2ZFDB 3OSEA 1V5SA 3TDHA 4EAKA 2QREA 2QRDA 2YA3A 2EHBD 2QLVA 4EAGA 3T4NA 2Y8QA
chains in the Genus database with same CATH superfamily
4IL8A 1D3UA 1NGMA 1YQRA 1UT4A 3PDKA 1QN9A 5JMVD 3F0ZA 2HL9A 4WZSD 3NA5A 1YTFA 1KYUA 3ASMA 1WJWA 2MJ7A 2QR1A 3KRMA 1PCZA 1JFIC 2NOEA 2NOLA 1QNCA 2OOYA 4RODB 3IH7A 4Q11A 5BMNA 5HSHA 1JDYA 1CDWA 2QRCA 1E42A 2DKCA 2LAEA 3D7QA 1LXTA 2D0AA 1VKLA 2JOIA 2FGTA 1KO9A 3UW2A 1RM1A 1P5GX 3F10A 1M3HA 3CWTA 1LWVA 2YA3A 2IV8A 2O3OA 3OLPA 4C7PA 1LWWA 2NOIA 1QN5A 3CW7A 2PWWA 3OSTA 2Y8QA 3OGDA 2JHJA 2DKDA 3CVTA 1YQLA 2NOBA 5AN4A 3RSMA 1UT7A 1PVSA 1QN4A 1KY6A 1TBAB 2NOFA 1TGHA 2H5AX 1YQMA 1QTPA 2NVMA 2NLVA 4QG5A 1VOLB 1TBPA 3KTUA 1K35A 2V8QA 1QN3A 2D0CA 1NVPA 2JPIA 1LWYA 3HS9A 1QNEA 1XSZA 2NWVA 2MZ8A 3OSMA 3OH6A 3CVSA 2I5WA 2NOZA 3HS8A 1MPGA 3OCIA 1VOKA 1C9BB 1QN8A 2FKMX 1K2YX 1VTOA 3EIKA 1VTLE 1PCMX 2QRDA 2JHNA 1C4GA 1DIZA 1J3MA 1C47A 2FUVA 1WQAA 4D7RA 4HJHA 4MRQA 1B9KA 1KYFA 4D7QA 2F7LA 4WXAA 2G30A 2VJ0A 2HZMA 3H1ZA 3OC3C 1YQKA 1MP9A 4EAJA 1FN7A 3I0WA 1KYDA 2XHIA 1T6AA 5IYCP 5EPCA 1NH2A 5IYDP 4CFFA 2ZFDB 3N89A 3OSEA 1V5SA 3TDHA 3VN5A 3SNSA 1QN7A 2HKPA 4TPSA 5F9CA 3D4VA 1EUVA 2Z0FA 3EAYA 4B0AA 5KL0A 1HU0A 1P5DX 1EBMA 2H4LX 5IYBP 2QLVA 4I8OA 1TUOA 2HZSA 2DKAA 3C04A 4ROEB 4ROCB 1QNBA 3TE5A 4BJUA 1YTBA 1N3AA 3CWSA 4EAIA 1R4XA 2Z8UA 4EALA 1PCJX 3BKQX 1QTSA 3ENOC 3CWUA 4EJZA 4DULA 2OOXA 1QNAA 1UL7A 1KFIA 3ULXA 2FKFA 2NOHA 1Q9UA 1M3QA 1PZDA 2HL8A 4PY5A 2V92A 5JN5A 3I3WA 2Y8LA 2D0BA 2V9JA 1AISA 3RPJA 3ENCA 1W80A 4WX8A 1KFQA 1KY7A 4EAKA 3CWAA 1M5Q1 3PMGA 3OH9A 2QREA 3I0XA 4EJYA 3DPUA 2EHBD 2R5XA 1N3CA 1N39A 2YH5A 3DPTA 4EAGA 1QN6A 2IV9A 3T4NA 5BMPA
chains in the Genus database with same CATH topology
3TE5A 4EAIA 4EALA 2OOXA 1UL7A 2QR1A 4EAJA 2V8QA 2OOYA 2V92A 2Y8LA 2V9JA 4CFFA 2QRCA 2ZFDB 3OSEA 1V5SA 3TDHA 4EAKA 2QREA 2QRDA 2YA3A 2EHBD 2QLVA 4EAGA 3T4NA 2Y8QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TE5 A;  4EAI A;  4EAL A;  2OOX A;  1UL7 A;  2QR1 A;  4EAJ A;  2V8Q A;  2OOY A;  2V92 A;  2Y8L A;  2V9J A;  4CFF A;  2QRC A;  2ZFD B;  3OSE A;  1V5S A;  3TDH A;  4EAK A;  2QRE A;  2QRD A;  2YA3 A;  2EHB D;  2QLV A;  4EAG A;  3T4N A;  2Y8Q A; 
#chains in the Genus database with same CATH topology
 4IL8 A;  1D3U A;  1NGM A;  1YQR A;  1UT4 A;  3PDK A;  1QN9 A;  5JMV D;  3F0Z A;  2HL9 A;  4WZS D;  3NA5 A;  1YTF A;  1KYU A;  3ASM A;  1WJW A;  2MJ7 A;  2QR1 A;  3KRM A;  1PCZ A;  1JFI C;  2NOE A;  2NOL A;  1QNC A;  2OOY A;  4ROD B;  3IH7 A;  4Q11 A;  5BMN A;  5HSH A;  1JDY A;  1CDW A;  2QRC A;  1E42 A;  2DKC A;  2LAE A;  3D7Q A;  1LXT A;  2D0A A;  1VKL A;  2JOI A;  2FGT A;  1KO9 A;  3UW2 A;  1RM1 A;  1P5G X;  3F10 A;  1M3H A;  3CWT A;  1LWV A;  2YA3 A;  2IV8 A;  2O3O A;  3OLP A;  4C7P A;  1LWW A;  2NOI A;  1QN5 A;  3CW7 A;  2PWW A;  3OST A;  2Y8Q A;  3OGD A;  2JHJ A;  2DKD A;  3CVT A;  1YQL A;  2NOB A;  5AN4 A;  3RSM A;  1UT7 A;  1PVS A;  1QN4 A;  1KY6 A;  1TBA B;  2NOF A;  1TGH A;  2H5A X;  1YQM A;  1QTP A;  2NVM A;  2NLV A;  4QG5 A;  1VOL B;  1TBP A;  3KTU A;  1K35 A;  2V8Q A;  1QN3 A;  2D0C A;  1NVP A;  2JPI A;  1LWY A;  3HS9 A;  1QNE A;  1XSZ A;  2NWV A;  2MZ8 A;  3OSM A;  3OH6 A;  3CVS A;  2I5W A;  2NOZ A;  3HS8 A;  1MPG A;  3OCI A;  1VOK A;  1C9B B;  1QN8 A;  2FKM X;  1K2Y X;  1VTO A;  3EIK A;  1VTL E;  1PCM X;  2QRD A;  2JHN A;  1C4G A;  1DIZ A;  1J3M A;  1C47 A;  2FUV A;  1WQA A;  4D7R A;  4HJH A;  4MRQ A;  1B9K A;  1KYF A;  4D7Q A;  2F7L A;  4WXA A;  2G30 A;  2VJ0 A;  2HZM A;  3H1Z A;  3OC3 C;  1YQK A;  1MP9 A;  4EAJ A;  1FN7 A;  3I0W A;  1KYD A;  2XHI A;  1T6A A;  5IYC P;  5EPC A;  1NH2 A;  5IYD P;  4CFF A;  2ZFD B;  3N89 A;  3OSE A;  1V5S A;  3TDH A;  3VN5 A;  3SNS A;  1QN7 A;  2HKP A;  4TPS A;  5F9C A;  3D4V A;  1EUV A;  2Z0F A;  3EAY A;  4B0A A;  5KL0 A;  1HU0 A;  1P5D X;  1EBM A;  2H4L X;  5IYB P;  2QLV A;  4I8O A;  1TUO A;  2HZS A;  2DKA A;  3C04 A;  4ROE B;  4ROC B;  1QNB A;  3TE5 A;  4BJU A;  1YTB A;  1N3A A;  3CWS A;  4EAI A;  1R4X A;  2Z8U A;  4EAL A;  1PCJ X;  3BKQ X;  1QTS A;  3ENO C;  3CWU A;  4EJZ A;  4DUL A;  2OOX A;  1QNA A;  1UL7 A;  1KFI A;  3ULX A;  2FKF A;  2NOH A;  1Q9U A;  1M3Q A;  1PZD A;  2HL8 A;  4PY5 A;  2V92 A;  5JN5 A;  3I3W A;  2Y8L A;  2D0B A;  2V9J A;  1AIS A;  3RPJ A;  3ENC A;  1W80 A;  4WX8 A;  1KFQ A;  1KY7 A;  4EAK A;  3CWA A;  1M5Q 1;  3PMG A;  3OH9 A;  2QRE A;  3I0X A;  4EJY A;  3DPU A;  2EHB D;  2R5X A;  1N3C A;  1N39 A;  2YH5 A;  3DPT A;  4EAG A;  1QN6 A;  2IV9 A;  3T4N A;  5BMP A; 
#chains in the Genus database with same CATH homology
 3TE5 A;  4EAI A;  4EAL A;  2OOX A;  1UL7 A;  2QR1 A;  4EAJ A;  2V8Q A;  2OOY A;  2V92 A;  2Y8L A;  2V9J A;  4CFF A;  2QRC A;  2ZFD B;  3OSE A;  1V5S A;  3TDH A;  4EAK A;  2QRE A;  2QRD A;  2YA3 A;  2EHB D;  2QLV A;  4EAG A;  3T4N A;  2Y8Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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