2YA3A

Structure of the regulatory fragment of mammalian ampk in complex with coumarin adp
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
156
structure length
102
Chain Sequence
MAWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDEVAPRPGSHTIEFFEMCANLIKNSCTV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of Mammalian Ampk and its Regulation by Adp
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1
total genus 21
structure length 102
sequence length 156
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2011-02-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2ya3A01
2V9JA 2QRDA 4EAKA 4EAGA 2ZFDB 2OOYA 4EALA 2QLVA 2YA3A 4EAJA 3TDHA 2QR1A 2V92A 2Y8LA 2V8QA 4CFFA 2Y8QA 1UL7A 3TE5A 4EAIA 3OSEA 3T4NA 1V5SA 2EHBD 2QREA 2QRCA 2OOXA
chains in the Genus database with same CATH superfamily
1QNEA 2NWVA 4IL8A 3OH9A 5AN4A 1YTFA 4PY5A 1QTSA 2H5AX 2QRDA 2G30A 1FN7A 2NOLA 3HS9A 2ZFDB 2FUVA 2FKMX 1TGHA 2Z8UA 2YH5A 3I0XA 2H4LX 1C4GA 1J3MA 4EAJA 1R4XA 5JMVD 1PCMX 4Q11A 1MPGA 3KTUA 3CWTA 5IYBP 1QN6A 4DULA 4WXAA 1DIZA 1LWWA 2NOFA 5JN5A 1QN3A 2V92A 1LWVA 2Y8LA 4WX8A 1QN7A 3N89A 1KO9A 4B0AA 4BJUA 2Y8QA 1UL7A 3CVTA 1WQAA 3CW7A 2HL8A 1TUOA 2Z0FA 1P5GX 1EUVA 2DKDA 2FGTA 1EBMA 1T6AA 2MJ7A 5EPCA 3T4NA 4D7QA 1AISA 2VJ0A 1JDYA 3ENCA 3HS8A 1K35A 1N3AA 4I8OA 2LAEA 1YQKA 2JPIA 1C9BB 4EAKA 1WJWA 3ASMA 2DKAA 1D3UA 1VOKA 4QG5A 1C47A 2NOHA 3D4VA 1YTBA 2OOYA 4EALA 1PCZA 1CDWA 1KYUA 1TBPA 2JOIA 2YA3A 2HZSA 4MRQA 1QN5A 1PVSA 3OCIA 1KFIA 3OH6A 5IYDP 1QNAA 1NVPA 3TDHA 2QR1A 1M5Q1 2D0CA 1K2YX 2HZMA 4HJHA 3PDKA 1VTOA 2NOEA 1XSZA 1KYFA 2MZ8A 1NH2A 2DKCA 2F7LA 3IH7A 2NOBA 1QTPA 4WZSD 2IV8A 1KY6A 3DPTA 1N3CA 1P5DX 1YQRA 2QRCA 1QNBA 3I3WA 1KYDA 4EJYA 3ULXA 1KFQA 4C7PA 1PZDA 3OLPA 4EAGA 2IV9A 2XHIA 1HU0A 1QN9A 1W80A 4D7RA 1B9KA 2QLVA 3KRMA 1QN4A 1VKLA 2I5WA 4ROCB 3PMGA 3BKQX 1M3QA 1UT4A 4RODB 5F9CA 1PCJX 3OGDA 5KL0A 2PWWA 2V8QA 4TPSA 3C04A 3OC3C 3CWAA 1M3HA 3EAYA 3EIKA 2NOZA 2JHJA 4EAIA 3SNSA 5HSHA 3OSMA 3OSEA 4EJZA 1V5SA 3DPUA 5BMNA 1QN8A 2FKFA 2QREA 3H1ZA 1Q9UA 2D0AA 1YQMA 2V9JA 2HL9A 1E42A 1UT7A 3D7QA 3F10A 1NGMA 2HKPA 1N39A 2JHNA 5BMPA 1QNCA 1KY7A 3UW2A 1VTLE 3RPJA 3CWUA 3ENOC 3F0ZA 5IYCP 1LWYA 1LXTA 1JFIC 2D0BA 1YQLA 3I0WA 1TBAB 4CFFA 3CVSA 2O3OA 3OSTA 2NVMA 3TE5A 1RM1A 3CWSA 4ROEB 3RSMA 1MP9A 2NLVA 1VOLB 3NA5A 2EHBD 2R5XA 3VN5A 2OOXA 2NOIA
chains in the Genus database with same CATH topology
2V9JA 2QRDA 4EAKA 4EAGA 2ZFDB 2OOYA 4EALA 2QLVA 2YA3A 4EAJA 3TDHA 2QR1A 2V92A 2Y8LA 2V8QA 4CFFA 2Y8QA 1UL7A 3TE5A 4EAIA 3OSEA 3T4NA 1V5SA 2EHBD 2QREA 2QRCA 2OOXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V9J A;  2QRD A;  4EAK A;  4EAG A;  2ZFD B;  2OOY A;  4EAL A;  2QLV A;  2YA3 A;  4EAJ A;  3TDH A;  2QR1 A;  2V92 A;  2Y8L A;  2V8Q A;  4CFF A;  2Y8Q A;  1UL7 A;  3TE5 A;  4EAI A;  3OSE A;  3T4N A;  1V5S A;  2EHB D;  2QRE A;  2QRC A;  2OOX A; 
#chains in the Genus database with same CATH topology
 1QNE A;  2NWV A;  4IL8 A;  3OH9 A;  5AN4 A;  1YTF A;  4PY5 A;  1QTS A;  2H5A X;  2QRD A;  2G30 A;  1FN7 A;  2NOL A;  3HS9 A;  2ZFD B;  2FUV A;  2FKM X;  1TGH A;  2Z8U A;  2YH5 A;  3I0X A;  2H4L X;  1C4G A;  1J3M A;  4EAJ A;  1R4X A;  5JMV D;  1PCM X;  4Q11 A;  1MPG A;  3KTU A;  3CWT A;  5IYB P;  1QN6 A;  4DUL A;  4WXA A;  1DIZ A;  1LWW A;  2NOF A;  5JN5 A;  1QN3 A;  2V92 A;  1LWV A;  2Y8L A;  4WX8 A;  1QN7 A;  3N89 A;  1KO9 A;  4B0A A;  4BJU A;  2Y8Q A;  1UL7 A;  3CVT A;  1WQA A;  3CW7 A;  2HL8 A;  1TUO A;  2Z0F A;  1P5G X;  1EUV A;  2DKD A;  2FGT A;  1EBM A;  1T6A A;  2MJ7 A;  5EPC A;  3T4N A;  4D7Q A;  1AIS A;  2VJ0 A;  1JDY A;  3ENC A;  3HS8 A;  1K35 A;  1N3A A;  4I8O A;  2LAE A;  1YQK A;  2JPI A;  1C9B B;  4EAK A;  1WJW A;  3ASM A;  2DKA A;  1D3U A;  1VOK A;  4QG5 A;  1C47 A;  2NOH A;  3D4V A;  1YTB A;  2OOY A;  4EAL A;  1PCZ A;  1CDW A;  1KYU A;  1TBP A;  2JOI A;  2YA3 A;  2HZS A;  4MRQ A;  1QN5 A;  1PVS A;  3OCI A;  1KFI A;  3OH6 A;  5IYD P;  1QNA A;  1NVP A;  3TDH A;  2QR1 A;  1M5Q 1;  2D0C A;  1K2Y X;  2HZM A;  4HJH A;  3PDK A;  1VTO A;  2NOE A;  1XSZ A;  1KYF A;  2MZ8 A;  1NH2 A;  2DKC A;  2F7L A;  3IH7 A;  2NOB A;  1QTP A;  4WZS D;  2IV8 A;  1KY6 A;  3DPT A;  1N3C A;  1P5D X;  1YQR A;  2QRC A;  1QNB A;  3I3W A;  1KYD A;  4EJY A;  3ULX A;  1KFQ A;  4C7P A;  1PZD A;  3OLP A;  4EAG A;  2IV9 A;  2XHI A;  1HU0 A;  1QN9 A;  1W80 A;  4D7R A;  1B9K A;  2QLV A;  3KRM A;  1QN4 A;  1VKL A;  2I5W A;  4ROC B;  3PMG A;  3BKQ X;  1M3Q A;  1UT4 A;  4ROD B;  5F9C A;  1PCJ X;  3OGD A;  5KL0 A;  2PWW A;  2V8Q A;  4TPS A;  3C04 A;  3OC3 C;  3CWA A;  1M3H A;  3EAY A;  3EIK A;  2NOZ A;  2JHJ A;  4EAI A;  3SNS A;  5HSH A;  3OSM A;  3OSE A;  4EJZ A;  1V5S A;  3DPU A;  5BMN A;  1QN8 A;  2FKF A;  2QRE A;  3H1Z A;  1Q9U A;  2D0A A;  1YQM A;  2V9J A;  2HL9 A;  1E42 A;  1UT7 A;  3D7Q A;  3F10 A;  1NGM A;  2HKP A;  1N39 A;  2JHN A;  5BMP A;  1QNC A;  1KY7 A;  3UW2 A;  1VTL E;  3RPJ A;  3CWU A;  3ENO C;  3F0Z A;  5IYC P;  1LWY A;  1LXT A;  1JFI C;  2D0B A;  1YQL A;  3I0W A;  1TBA B;  4CFF A;  3CVS A;  2O3O A;  3OST A;  2NVM A;  3TE5 A;  1RM1 A;  3CWS A;  4ROE B;  3RSM A;  1MP9 A;  2NLV A;  1VOL B;  3NA5 A;  2EHB D;  2R5X A;  3VN5 A;  2OOX A;  2NOI A; 
#chains in the Genus database with same CATH homology
 2V9J A;  2QRD A;  4EAK A;  4EAG A;  2ZFD B;  2OOY A;  4EAL A;  2QLV A;  2YA3 A;  4EAJ A;  3TDH A;  2QR1 A;  2V92 A;  2Y8L A;  2V8Q A;  4CFF A;  2Y8Q A;  1UL7 A;  3TE5 A;  4EAI A;  3OSE A;  3T4N A;  1V5S A;  2EHB D;  2QRE A;  2QRC A;  2OOX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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