3OSEA

Structure of the kinase associated domain 1 (ka1) from mark1 kinase
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
100
structure length
100
Chain Sequence
KPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Kinase Associated-1 Domains Drive MARK/PAR1 Kinases to Membrane Targets by Binding Acidic Phospholipids.
pubmed doi rcsb
molecule tags Lipid binding protein
source organism Homo sapiens
molecule keywords Serine/threonine-protein kinase MARK1
total genus 27
structure length 100
sequence length 100
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2010-09-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02149 KA1 Kinase associated domain 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 3oseA00
2QRDA 4EAIA 2QLVA 2Y8QA 2OOYA 4EALA 4EAJA 2QR1A 1UL7A 2QREA 3T4NA 3TE5A 2V92A 2V8QA 2OOXA 4CFFA 4EAKA 2YA3A 3OSEA 2EHBD 2ZFDB 2V9JA 4EAGA 2Y8LA 2QRCA 1V5SA 3TDHA
chains in the Genus database with same CATH superfamily
4HJHA 1EBMA 4BJUA 1QNAA 3HS8A 1N39A 5HSHA 1T6AA 3NA5A 3I3WA 3CWUA 2Z8UA 3D4VA 2QREA 4IL8A 2D0BA 3ASMA 4EJZA 1QNEA 4WXAA 2V8QA 4CFFA 4Q11A 1NVPA 5AN4A 1YTFA 1K35A 1TBAB 4PY5A 1N3CA 3DPUA 1TUOA 2PWWA 2HZSA 2V9JA 1Q9UA 1VKLA 3OLPA 4EAGA 1C9BB 1M3QA 2DKAA 4D7QA 1QN6A 3UW2A 4ROEB 1CDWA 1JDYA 1KYUA 3ULXA 5F9CA 1TGHA 1VOKA 2NOFA 2JOIA 2QRDA 1B9KA 1KFQA 2DKDA 3PDKA 4WX8A 5BMPA 1JFIC 2G30A 1D3UA 2QLVA 2OOYA 3F0ZA 1QNCA 4EAJA 2D0AA 2QR1A 2D0CA 1UL7A 3D7QA 1MPGA 1YQKA 3N89A 3ENCA 2DKCA 2H4LX 2HL8A 3HS9A 3TE5A 1M3HA 4RODB 4D7RA 2NOZA 2HL9A 3OC3C 2NOIA 3ENOC 5IYBP 2YA3A 4DULA 3EAYA 3CVTA 2IV9A 5IYCP 1PZDA 2NOEA 2EHBD 3VN5A 5IYDP 2XHIA 3OGDA 2Y8LA 3CVSA 1VOLB 3OSMA 2MJ7A 1QTSA 2NVMA 4I8OA 3CWAA 2NLVA 1M5Q1 4TPSA 3I0WA 1NH2A 2I5WA 3CWTA 2JHNA 3OCIA 1VTLE 2NWVA 1QN7A 4EAIA 1KFIA 3IH7A 3OH6A 3OSTA 1YTBA 3RPJA 1N3AA 1LWVA 1C47A 1DIZA 3KTUA 3I0XA 3H1ZA 1LWYA 1YQLA 3BKQX 3CW7A 1YQRA 2HZMA 4EJYA 1WQAA 1PCZA 2V92A 2JPIA 2OOXA 2HKPA 1EUVA 1KYFA 1TBPA 2R5XA 4EAKA 1QTPA 1QNBA 1LXTA 2O3OA 1FN7A 1QN5A 1WJWA 3F10A 1MP9A 2IV8A 1HU0A 1NGMA 1YQMA 1KYDA 4WZSD 2VJ0A 1QN9A 2NOLA 2FKFA 2Z0FA 2QRCA 1QN8A 4MRQA 1P5DX 1QN3A 1K2YX 3DPTA 3PMGA 3RSMA 2LAEA 4B0AA 3C04A 5BMNA 1RM1A 5JMVD 2Y8QA 2NOBA 3KRMA 1C4GA 4EALA 1AISA 1KY7A 5JN5A 1QN4A 2FGTA 1E42A 3T4NA 1W80A 3SNSA 2JHJA 2F7LA 1KO9A 1PVSA 1UT7A 4ROCB 1VTOA 3EIKA 2YH5A 1KY6A 1J3MA 4QG5A 5EPCA 1PCJX 3OSEA 4C7PA 1R4XA 2FUVA 2ZFDB 1PCMX 1XSZA 2MZ8A 3OH9A 5KL0A 2FKMX 1V5SA 1UT4A 2H5AX 1LWWA 2NOHA 1P5GX 3TDHA 3CWSA
chains in the Genus database with same CATH topology
2QRDA 4EAIA 2QLVA 2Y8QA 2OOYA 4EALA 4EAJA 2QR1A 1UL7A 2QREA 3T4NA 3TE5A 2V92A 2V8QA 2OOXA 4CFFA 4EAKA 2YA3A 3OSEA 2EHBD 2ZFDB 2V9JA 4EAGA 2Y8LA 2QRCA 1V5SA 3TDHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QRD A;  4EAI A;  2QLV A;  2Y8Q A;  2OOY A;  4EAL A;  4EAJ A;  2QR1 A;  1UL7 A;  2QRE A;  3T4N A;  3TE5 A;  2V92 A;  2V8Q A;  2OOX A;  4CFF A;  4EAK A;  2YA3 A;  3OSE A;  2EHB D;  2ZFD B;  2V9J A;  4EAG A;  2Y8L A;  2QRC A;  1V5S A;  3TDH A; 
#chains in the Genus database with same CATH topology
 4HJH A;  1EBM A;  4BJU A;  1QNA A;  3HS8 A;  1N39 A;  5HSH A;  1T6A A;  3NA5 A;  3I3W A;  3CWU A;  2Z8U A;  3D4V A;  2QRE A;  4IL8 A;  2D0B A;  3ASM A;  4EJZ A;  1QNE A;  4WXA A;  2V8Q A;  4CFF A;  4Q11 A;  1NVP A;  5AN4 A;  1YTF A;  1K35 A;  1TBA B;  4PY5 A;  1N3C A;  3DPU A;  1TUO A;  2PWW A;  2HZS A;  2V9J A;  1Q9U A;  1VKL A;  3OLP A;  4EAG A;  1C9B B;  1M3Q A;  2DKA A;  4D7Q A;  1QN6 A;  3UW2 A;  4ROE B;  1CDW A;  1JDY A;  1KYU A;  3ULX A;  5F9C A;  1TGH A;  1VOK A;  2NOF A;  2JOI A;  2QRD A;  1B9K A;  1KFQ A;  2DKD A;  3PDK A;  4WX8 A;  5BMP A;  1JFI C;  2G30 A;  1D3U A;  2QLV A;  2OOY A;  3F0Z A;  1QNC A;  4EAJ A;  2D0A A;  2QR1 A;  2D0C A;  1UL7 A;  3D7Q A;  1MPG A;  1YQK A;  3N89 A;  3ENC A;  2DKC A;  2H4L X;  2HL8 A;  3HS9 A;  3TE5 A;  1M3H A;  4ROD B;  4D7R A;  2NOZ A;  2HL9 A;  3OC3 C;  2NOI A;  3ENO C;  5IYB P;  2YA3 A;  4DUL A;  3EAY A;  3CVT A;  2IV9 A;  5IYC P;  1PZD A;  2NOE A;  2EHB D;  3VN5 A;  5IYD P;  2XHI A;  3OGD A;  2Y8L A;  3CVS A;  1VOL B;  3OSM A;  2MJ7 A;  1QTS A;  2NVM A;  4I8O A;  3CWA A;  2NLV A;  1M5Q 1;  4TPS A;  3I0W A;  1NH2 A;  2I5W A;  3CWT A;  2JHN A;  3OCI A;  1VTL E;  2NWV A;  1QN7 A;  4EAI A;  1KFI A;  3IH7 A;  3OH6 A;  3OST A;  1YTB A;  3RPJ A;  1N3A A;  1LWV A;  1C47 A;  1DIZ A;  3KTU A;  3I0X A;  3H1Z A;  1LWY A;  1YQL A;  3BKQ X;  3CW7 A;  1YQR A;  2HZM A;  4EJY A;  1WQA A;  1PCZ A;  2V92 A;  2JPI A;  2OOX A;  2HKP A;  1EUV A;  1KYF A;  1TBP A;  2R5X A;  4EAK A;  1QTP A;  1QNB A;  1LXT A;  2O3O A;  1FN7 A;  1QN5 A;  1WJW A;  3F10 A;  1MP9 A;  2IV8 A;  1HU0 A;  1NGM A;  1YQM A;  1KYD A;  4WZS D;  2VJ0 A;  1QN9 A;  2NOL A;  2FKF A;  2Z0F A;  2QRC A;  1QN8 A;  4MRQ A;  1P5D X;  1QN3 A;  1K2Y X;  3DPT A;  3PMG A;  3RSM A;  2LAE A;  4B0A A;  3C04 A;  5BMN A;  1RM1 A;  5JMV D;  2Y8Q A;  2NOB A;  3KRM A;  1C4G A;  4EAL A;  1AIS A;  1KY7 A;  5JN5 A;  1QN4 A;  2FGT A;  1E42 A;  3T4N A;  1W80 A;  3SNS A;  2JHJ A;  2F7L A;  1KO9 A;  1PVS A;  1UT7 A;  4ROC B;  1VTO A;  3EIK A;  2YH5 A;  1KY6 A;  1J3M A;  4QG5 A;  5EPC A;  1PCJ X;  3OSE A;  4C7P A;  1R4X A;  2FUV A;  2ZFD B;  1PCM X;  1XSZ A;  2MZ8 A;  3OH9 A;  5KL0 A;  2FKM X;  1V5S A;  1UT4 A;  2H5A X;  1LWW A;  2NOH A;  1P5G X;  3TDH A;  3CWS A; 
#chains in the Genus database with same CATH homology
 2QRD A;  4EAI A;  2QLV A;  2Y8Q A;  2OOY A;  4EAL A;  4EAJ A;  2QR1 A;  1UL7 A;  2QRE A;  3T4N A;  3TE5 A;  2V92 A;  2V8Q A;  2OOX A;  4CFF A;  4EAK A;  2YA3 A;  3OSE A;  2EHB D;  2ZFD B;  2V9J A;  4EAG A;  2Y8L A;  2QRC A;  1V5S A;  3TDH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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