4B0AA

The high-resolution structure of ytbp-ytaf1 identifies conserved and competing interaction surfaces in transcriptional activation
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
256
structure length
237
Chain Sequence
KTNLANEDEAYEAIFGGEFGSLEIGSYIGGDEARNSKDYTEHLPDAVDFEDEDELADDGIVPTLQNIVATVTLGCRLDLKTVALHARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSEDDSKLASRKYARIIQKIGFAAKFTDFKIQNIVGSCDVKFPIRLEGLAFSHGTFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKQREEIYQAFEAIYPVLSEFRKM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title High-Resolution Structure of TBP with Taf1 Reveals Anchoring Patterns in Transcriptional Regulation
pubmed doi rcsb
molecule tags Transcription
source organism Saccharomyces cerevisiae
molecule keywords TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1, LINKER, TAT
total genus 58
structure length 237
sequence length 256
ec nomenclature ec 2.3.1.48: Histone acetyltransferase.
pdb deposition date 2012-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00352 TBP Transcription factor TFIID (or TATA-binding protein, TBP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 4b0aA01
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 4b0aA02
2MJ7A 3VN5A 1RM1A 1D3UA 3EIKA 1C9BB 2D0CA 4RODB 4WZSD 4ROCB 1QN9A 1QN4A 5IYBP 1TGHA 1QTPA 3H1ZA 1QNEA 1QNBA 2IV9A 1VTLE 1QNAA 1KYFA 3OC3C 1QNCA 1KY7A 1VOLB 2D0AA 1YTFA 3HS8A 2Z8UA 1TBPA 2G30A 4B0AA 1VOKA 1QN3A 3HS9A 3OCIA 1W80A 5IYCP 1QN5A 1AISA 1QN8A 1YTBA 1NVPA 1KYDA 2IV8A 1PCZA 1NGMA 5IYDP 1PZDA 1B9KA 4ROEB 1KYUA 4PY5A 1JFIC 1QN6A 3ASMA 2D0BA 1CDWA 1MP9A 1TBAB 1E42A 1NH2A 1VTOA 1QN7A 1KY6A 2VJ0A 1R4XA 1QTSA
chains in the Genus database with same CATH superfamily
2EHBD 3T4NA 3VN5A 2JHJA 3EIKA 2HKPA 4D7QA 4WZSD 3CVSA 3RSMA 5JN5A 1TGHA 2NOFA 5JMVD 3ULXA 2I5WA 4WX8A 2NWVA 1QNAA 4EAJA 5BMPA 1K2YX 2F7LA 1VOLB 5KL0A 1C47A 1TBPA 2Z8UA 1PCMX 5BMNA 1UT7A 2FGTA 3I0WA 4EJYA 2V92A 3OSMA 1LWVA 1UT4A 2IV8A 1NGMA 1PZDA 4BJUA 2ZFDB 4QG5A 3ASMA 1CDWA 2Z0FA 2V9JA 3N89A 1MPGA 1QN7A 3KTUA 3IH7A 1P5DX 1QTSA 1EUVA 1YQLA 1RM1A 3F10A 4I8OA 1C4GA 2D0CA 3ENCA 4EJZA 4EAIA 3D7QA 1QN4A 1JDYA 1LXTA 3OH9A 2NLVA 3H1ZA 2LAEA 3CWAA 4EAGA 2O3OA 3DPTA 1N3CA 1P5GX 2NOHA 2D0AA 1TUOA 1LWWA 2QREA 3DPUA 1FN7A 5HSHA 1YTBA 1QN8A 1NVPA 3NA5A 3PDKA 2JPIA 3KRMA 3EAYA 1KYUA 1WQAA 4PY5A 2PWWA 1M3HA 1KFIA 2YA3A 1M5Q1 2OOXA 1TBAB 1E42A 3SNSA 3OSEA 1NH2A 2QRCA 4EALA 3OGDA 1QNEA 2VJ0A 1R4XA 5AN4A 3D4VA 4CFFA 3UW2A 2MJ7A 1YTFA 1D3UA 2XHIA 4RODB 1QN9A 2H4LX 5IYBP 3F0ZA 2QLVA 1T6AA 4C7PA 1J3MA 4Q11A 1QTPA 4TPSA 3C04A 2NOZA 2NOLA 3RPJA 1YQRA 3TE5A 2HL9A 4MRQA 2IV9A 2DKDA 1VTLE 1KYFA 2DKAA 3I3WA 3OC3C 1N39A 1LWYA 2HZMA 1KY7A 4HJHA 3HS8A 1DIZA 2G30A 1V5SA 1UL7A 2FKFA 3BKQX 1W80A 3OCIA 4IL8A 3I0XA 1AISA 1QN5A 3CWTA 1KYDA 2Y8QA 1KO9A 3CW7A 5IYDP 3OH6A 2QR1A 2DKCA 2R5XA 3ENOC 1JFIC 2QRDA 2FKMX 1QN6A 2D0BA 1VTOA 1YQKA 2NOBA 4EAKA 1PCJX 5F9CA 2YH5A 1C9BB 1WJWA 2JHNA 4ROCB 1EBMA 3CWSA 3OLPA 4DULA 1XSZA 2HL8A 3PMGA 1QNBA 5EPCA 2FUVA 1K35A 1QNCA 1PVSA 1HU0A 2NOIA 1VKLA 1QN3A 4B0AA 4D7RA 1VOKA 1YQMA 2OOYA 3HS9A 5IYCP 1Q9UA 2V8QA 1PCZA 2NVMA 3TDHA 2MZ8A 2NOEA 3CVTA 1B9KA 2Y8LA 4ROEB 2JOIA 4WXAA 2H5AX 1MP9A 3CWUA 3OSTA 1KY6A 1M3QA 2HZSA 1KFQA 1N3AA
chains in the Genus database with same CATH topology
3VN5A 3EIKA 4WZSD 1TGHA 2NOFA 3ULXA 2I5WA 1QNAA 1VOLB 2Z8UA 1TBPA 1UT7A 2FGTA 3I0WA 4EJYA 3OSMA 1LWVA 1UT4A 2IV8A 1NGMA 1PZDA 3ASMA 1CDWA 3N89A 1QN7A 3KTUA 3IH7A 1QTSA 1YQLA 1RM1A 3F10A 4I8OA 2D0CA 4EJZA 1QN4A 3H1ZA 2LAEA 2O3OA 3DPTA 1N3CA 2NOHA 2D0AA 1LWWA 3DPUA 1FN7A 1YTBA 1QN8A 1NVPA 3KRMA 1KYUA 4PY5A 1M3HA 1TBAB 1E42A 3SNSA 1NH2A 1QNEA 2VJ0A 5AN4A 1R4XA 1YTFA 2MJ7A 1D3UA 2XHIA 4RODB 1QN9A 5IYBP 3F0ZA 4Q11A 4TPSA 1QTPA 2NOZA 2NOLA 3RPJA 1YQRA 2IV9A 1VTLE 1KYFA 1N39A 3OC3C 1LWYA 2HZMA 1KY7A 3HS8A 2G30A 3OCIA 1W80A 3I0XA 1QN5A 1AISA 1KYDA 1KO9A 5IYDP 1JFIC 1QN6A 2D0BA 1VTOA 1YQKA 2NOBA 2YH5A 1C9BB 4ROCB 1EBMA 4DULA 1QNBA 1QNCA 1HU0A 2NOIA 1QN3A 4B0AA 1YQMA 1VOKA 3HS9A 5IYCP 1PCZA 2NOEA 2MZ8A 1B9KA 4ROEB 2JOIA 1MP9A 3OSTA 1KY6A 1M3QA 2HZSA 1N3AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MJ7 A;  3VN5 A;  1RM1 A;  1D3U A;  3EIK A;  1C9B B;  2D0C A;  4ROD B;  4WZS D;  4ROC B;  1QN9 A;  1QN4 A;  5IYB P;  1TGH A;  1QTP A;  3H1Z A;  1QNE A;  1QNB A;  2IV9 A;  1VTL E;  1QNA A;  1KYF A;  3OC3 C;  1QNC A;  1KY7 A;  1VOL B;  2D0A A;  1YTF A;  3HS8 A;  2Z8U A;  1TBP A;  2G30 A;  4B0A A;  1VOK A;  1QN3 A;  3HS9 A;  3OCI A;  1W80 A;  5IYC P;  1QN5 A;  1AIS A;  1QN8 A;  1YTB A;  1NVP A;  1KYD A;  2IV8 A;  1PCZ A;  1NGM A;  5IYD P;  1PZD A;  1B9K A;  4ROE B;  1KYU A;  4PY5 A;  1JFI C;  1QN6 A;  3ASM A;  2D0B A;  1CDW A;  1MP9 A;  1TBA B;  1E42 A;  1NH2 A;  1VTO A;  1QN7 A;  1KY6 A;  2VJ0 A;  1R4X A;  1QTS A; 
#chains in the Genus database with same CATH topology
 2EHB D;  3T4N A;  3VN5 A;  2JHJ A;  3EIK A;  2HKP A;  4D7Q A;  4WZS D;  3CVS A;  3RSM A;  5JN5 A;  1TGH A;  2NOF A;  5JMV D;  3ULX A;  2I5W A;  4WX8 A;  2NWV A;  1QNA A;  4EAJ A;  5BMP A;  1K2Y X;  2F7L A;  1VOL B;  5KL0 A;  1C47 A;  1TBP A;  2Z8U A;  1PCM X;  5BMN A;  1UT7 A;  2FGT A;  3I0W A;  4EJY A;  2V92 A;  3OSM A;  1LWV A;  1UT4 A;  2IV8 A;  1NGM A;  1PZD A;  4BJU A;  2ZFD B;  4QG5 A;  3ASM A;  1CDW A;  2Z0F A;  2V9J A;  3N89 A;  1MPG A;  1QN7 A;  3KTU A;  3IH7 A;  1P5D X;  1QTS A;  1EUV A;  1YQL A;  1RM1 A;  3F10 A;  4I8O A;  1C4G A;  2D0C A;  3ENC A;  4EJZ A;  4EAI A;  3D7Q A;  1QN4 A;  1JDY A;  1LXT A;  3OH9 A;  2NLV A;  3H1Z A;  2LAE A;  3CWA A;  4EAG A;  2O3O A;  3DPT A;  1N3C A;  1P5G X;  2NOH A;  2D0A A;  1TUO A;  1LWW A;  2QRE A;  3DPU A;  1FN7 A;  5HSH A;  1YTB A;  1QN8 A;  1NVP A;  3NA5 A;  3PDK A;  2JPI A;  3KRM A;  3EAY A;  1KYU A;  1WQA A;  4PY5 A;  2PWW A;  1M3H A;  1KFI A;  2YA3 A;  1M5Q 1;  2OOX A;  1TBA B;  1E42 A;  3SNS A;  3OSE A;  1NH2 A;  2QRC A;  4EAL A;  3OGD A;  1QNE A;  2VJ0 A;  1R4X A;  5AN4 A;  3D4V A;  4CFF A;  3UW2 A;  2MJ7 A;  1YTF A;  1D3U A;  2XHI A;  4ROD B;  1QN9 A;  2H4L X;  5IYB P;  3F0Z A;  2QLV A;  1T6A A;  4C7P A;  1J3M A;  4Q11 A;  1QTP A;  4TPS A;  3C04 A;  2NOZ A;  2NOL A;  3RPJ A;  1YQR A;  3TE5 A;  2HL9 A;  4MRQ A;  2IV9 A;  2DKD A;  1VTL E;  1KYF A;  2DKA A;  3I3W A;  3OC3 C;  1N39 A;  1LWY A;  2HZM A;  1KY7 A;  4HJH A;  3HS8 A;  1DIZ A;  2G30 A;  1V5S A;  1UL7 A;  2FKF A;  3BKQ X;  1W80 A;  3OCI A;  4IL8 A;  3I0X A;  1AIS A;  1QN5 A;  3CWT A;  1KYD A;  2Y8Q A;  1KO9 A;  3CW7 A;  5IYD P;  3OH6 A;  2QR1 A;  2DKC A;  2R5X A;  3ENO C;  1JFI C;  2QRD A;  2FKM X;  1QN6 A;  2D0B A;  1VTO A;  1YQK A;  2NOB A;  4EAK A;  1PCJ X;  5F9C A;  2YH5 A;  1C9B B;  1WJW A;  2JHN A;  4ROC B;  1EBM A;  3CWS A;  3OLP A;  4DUL A;  1XSZ A;  2HL8 A;  3PMG A;  1QNB A;  5EPC A;  2FUV A;  1K35 A;  1QNC A;  1PVS A;  1HU0 A;  2NOI A;  1VKL A;  1QN3 A;  4B0A A;  4D7R A;  1VOK A;  1YQM A;  2OOY A;  3HS9 A;  5IYC P;  1Q9U A;  2V8Q A;  1PCZ A;  2NVM A;  3TDH A;  2MZ8 A;  2NOE A;  3CVT A;  1B9K A;  2Y8L A;  4ROE B;  2JOI A;  4WXA A;  2H5A X;  1MP9 A;  3CWU A;  3OST A;  1KY6 A;  1M3Q A;  2HZS A;  1KFQ A;  1N3A A; 
#chains in the Genus database with same CATH homology
 3VN5 A;  3EIK A;  4WZS D;  1TGH A;  2NOF A;  3ULX A;  2I5W A;  1QNA A;  1VOL B;  2Z8U A;  1TBP A;  1UT7 A;  2FGT A;  3I0W A;  4EJY A;  3OSM A;  1LWV A;  1UT4 A;  2IV8 A;  1NGM A;  1PZD A;  3ASM A;  1CDW A;  3N89 A;  1QN7 A;  3KTU A;  3IH7 A;  1QTS A;  1YQL A;  1RM1 A;  3F10 A;  4I8O A;  2D0C A;  4EJZ A;  1QN4 A;  3H1Z A;  2LAE A;  2O3O A;  3DPT A;  1N3C A;  2NOH A;  2D0A A;  1LWW A;  3DPU A;  1FN7 A;  1YTB A;  1QN8 A;  1NVP A;  3KRM A;  1KYU A;  4PY5 A;  1M3H A;  1TBA B;  1E42 A;  3SNS A;  1NH2 A;  1QNE A;  2VJ0 A;  5AN4 A;  1R4X A;  1YTF A;  2MJ7 A;  1D3U A;  2XHI A;  4ROD B;  1QN9 A;  5IYB P;  3F0Z A;  4Q11 A;  4TPS A;  1QTP A;  2NOZ A;  2NOL A;  3RPJ A;  1YQR A;  2IV9 A;  1VTL E;  1KYF A;  1N39 A;  3OC3 C;  1LWY A;  2HZM A;  1KY7 A;  3HS8 A;  2G30 A;  3OCI A;  1W80 A;  3I0X A;  1QN5 A;  1AIS A;  1KYD A;  1KO9 A;  5IYD P;  1JFI C;  1QN6 A;  2D0B A;  1VTO A;  1YQK A;  2NOB A;  2YH5 A;  1C9B B;  4ROC B;  1EBM A;  4DUL A;  1QNB A;  1QNC A;  1HU0 A;  2NOI A;  1QN3 A;  4B0A A;  1YQM A;  1VOK A;  3HS9 A;  5IYC P;  1PCZ A;  2NOE A;  2MZ8 A;  1B9K A;  4ROE B;  2JOI A;  1MP9 A;  3OST A;  1KY6 A;  1M3Q A;  2HZS A;  1N3A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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