4EAJ | Genus

Total Genus 23

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	23
sequence length	100
structure length	100
Chain Sequence	AKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDGGGGGGGSHTIEFFEMCANLIKILA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 100 atoms

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Transferase
source organism	Rattus norvegicus
publication title	AMP-activated protein kinase undergoes nucleotide-dependent conformational changes pubmed doi rcsb
molecule keywords	5'-AMP-activated protein kinase catalytic subunit alpha-1
total genus	23
structure length	100
sequence length	100
ec nomenclature	ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date	2012-03-22

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.310.80	Alpha Beta	2-Layer Sandwich	TATA-Binding Protein	Kinase associated domain 1, KA1	4eajA01

2Y8QA 2QRDA 2V8QA 1V5SA 1UL7A 3TE5A 2OOXA 2QRCA 3OSEA 4EAJA 2Y8LA 2EHBD 4EALA 2ZFDB 4CFFA 4EAIA 2QR1A 2QREA 2OOYA 2YA3A 3T4NA 2QLVA 4EAGA 3TDHA 2V9JA 2V92A 4EAKA
chains in the Genus database with same CATH superfamily

2D0CA 2Y8QA 2DKAA 2NLVA 1PCJX 3F0ZA 2NOLA 2XHIA 2MZ8A 3ENOC 5EPCA 3KTUA 1JFIC 1WQAA 2OOXA 1K35A 3ULXA 4EAJA 3D4VA 3CVSA 2NOFA 4B0AA 1AISA 1QNEA 1KYFA 4I8OA 1TGHA 2DKDA 1E42A 2EHBD 2IV9A 2R5XA 4EALA 1QNCA 2FUVA 3EAYA 3F10A 5IYBP 1QN9A 5HSHA 1VOKA 2NOBA 2HZMA 4MRQA 3OC3C 1YQLA 1PZDA 3HS8A 1NVPA 1YTBA 2NOIA 3EIKA 2QR1A 2V92A 4WZSD 1KFIA 5JN5A 5KL0A 3NA5A 3PMGA 4EAGA 2D0AA 3CWSA 1TBPA 3TDHA 2MJ7A 3KRMA 2HL9A 2HZSA 2JHNA 1R4XA 1NGMA 3IH7A 1MPGA 4Q11A 2JHJA 1PCZA 1V5SA 1UL7A 2G30A 3OLPA 2QRCA 4WX8A 1N3AA 1M3HA 4RODB 1N39A 1KYUA 3PDKA 4IL8A 3RSMA 1QN3A 1YQMA 3DPUA 1P5GX 5F9CA 3OGDA 2I5WA 1P5DX 2HKPA 1KYDA 5IYCP 1MP9A 1UT7A 3UW2A 1RM1A 1LXTA 1PCMX 2QREA 2YA3A 1QNAA 2NOHA 1W80A 3H1ZA 2NOZA 5AN4A 3I0XA 2VJ0A 1LWVA 1PVSA 3C04A 1EBMA 1QN5A 3N89A 2QLVA 2H5AX 1TBAB 1YQKA 2QRDA 3OH6A 1VTOA 2FGTA 1QN6A 1C4GA 4DULA 1CDWA 3VN5A 4ROEB 1T6AA 1QN4A 2Z0FA 2NWVA 2FKFA 3CW7A 4C7PA 1LWYA 1KFQA 3BKQX 4TPSA 3D7QA 1C9BB 1K2YX 1Q9UA 3I3WA 1EUVA 4WXAA 1B9KA 1N3CA 1DIZA 3CWAA 3CWUA 3I0WA 4EJYA 5IYDP 2FKMX 2IV8A 5BMPA 2DKCA 1QTSA 4D7QA 1J3MA 4PY5A 2D0BA 2V9JA 2JOIA 4EAKA 1VOLB 4BJUA 2F7LA 5BMNA 2V8QA 4HJHA 3OSMA 4QG5A 3TE5A 1FN7A 2HL8A 1KY6A 3OSEA 3OSTA 3CWTA 1KY7A 3CVTA 3ENCA 1QN8A 1UT4A 4EJZA 1YTFA 1VTLE 5JMVD 3DPTA 1M5Q1 1XSZA 1VKLA 3SNSA 2Y8LA 2O3OA 2Z8UA 1M3QA 2PWWA 2YH5A 1LWWA 2JPIA 1HU0A 2ZFDB 4CFFA 4EAIA 1YQRA 3RPJA 2OOYA 2LAEA 2NVMA 3OH9A 1JDYA 4D7RA 1QN7A 3T4NA 1D3UA 1QTPA 2NOEA 1TUOA 1QNBA 1KO9A 3ASMA 3HS9A 3OCIA 1WJWA 1NH2A 1C47A 2H4LX 4ROCB
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2Y8Q A;  2QRD A;  2V8Q A;  1V5S A;  1UL7 A;  3TE5 A;  2OOX A;  2QRC A;  3OSE A;  4EAJ A;  2Y8L A;  2EHB D;  4EAL A;  2ZFD B;  4CFF A;  4EAI A;  2QR1 A;  2QRE A;  2OOY A;  2YA3 A;  3T4N A;  2QLV A;  4EAG A;  3TDH A;  2V9J A;  2V92 A;  4EAK A; 
#chains in the Genus database with same CATH topology
 2D0C A;  2Y8Q A;  2DKA A;  2NLV A;  1PCJ X;  3F0Z A;  2NOL A;  2XHI A;  2MZ8 A;  3ENO C;  5EPC A;  3KTU A;  1JFI C;  1WQA A;  2OOX A;  1K35 A;  3ULX A;  4EAJ A;  3D4V A;  3CVS A;  2NOF A;  4B0A A;  1AIS A;  1QNE A;  1KYF A;  4I8O A;  1TGH A;  2DKD A;  1E42 A;  2EHB D;  2IV9 A;  2R5X A;  4EAL A;  1QNC A;  2FUV A;  3EAY A;  3F10 A;  5IYB P;  1QN9 A;  5HSH A;  1VOK A;  2NOB A;  2HZM A;  4MRQ A;  3OC3 C;  1YQL A;  1PZD A;  3HS8 A;  1NVP A;  1YTB A;  2NOI A;  3EIK A;  2QR1 A;  2V92 A;  4WZS D;  1KFI A;  5JN5 A;  5KL0 A;  3NA5 A;  3PMG A;  4EAG A;  2D0A A;  3CWS A;  1TBP A;  3TDH A;  2MJ7 A;  3KRM A;  2HL9 A;  2HZS A;  2JHN A;  1R4X A;  1NGM A;  3IH7 A;  1MPG A;  4Q11 A;  2JHJ A;  1PCZ A;  1V5S A;  1UL7 A;  2G30 A;  3OLP A;  2QRC A;  4WX8 A;  1N3A A;  1M3H A;  4ROD B;  1N39 A;  1KYU A;  3PDK A;  4IL8 A;  3RSM A;  1QN3 A;  1YQM A;  3DPU A;  1P5G X;  5F9C A;  3OGD A;  2I5W A;  1P5D X;  2HKP A;  1KYD A;  5IYC P;  1MP9 A;  1UT7 A;  3UW2 A;  1RM1 A;  1LXT A;  1PCM X;  2QRE A;  2YA3 A;  1QNA A;  2NOH A;  1W80 A;  3H1Z A;  2NOZ A;  5AN4 A;  3I0X A;  2VJ0 A;  1LWV A;  1PVS A;  3C04 A;  1EBM A;  1QN5 A;  3N89 A;  2QLV A;  2H5A X;  1TBA B;  1YQK A;  2QRD A;  3OH6 A;  1VTO A;  2FGT A;  1QN6 A;  1C4G A;  4DUL A;  1CDW A;  3VN5 A;  4ROE B;  1T6A A;  1QN4 A;  2Z0F A;  2NWV A;  2FKF A;  3CW7 A;  4C7P A;  1LWY A;  1KFQ A;  3BKQ X;  4TPS A;  3D7Q A;  1C9B B;  1K2Y X;  1Q9U A;  3I3W A;  1EUV A;  4WXA A;  1B9K A;  1N3C A;  1DIZ A;  3CWA A;  3CWU A;  3I0W A;  4EJY A;  5IYD P;  2FKM X;  2IV8 A;  5BMP A;  2DKC A;  1QTS A;  4D7Q A;  1J3M A;  4PY5 A;  2D0B A;  2V9J A;  2JOI A;  4EAK A;  1VOL B;  4BJU A;  2F7L A;  5BMN A;  2V8Q A;  4HJH A;  3OSM A;  4QG5 A;  3TE5 A;  1FN7 A;  2HL8 A;  1KY6 A;  3OSE A;  3OST A;  3CWT A;  1KY7 A;  3CVT A;  3ENC A;  1QN8 A;  1UT4 A;  4EJZ A;  1YTF A;  1VTL E;  5JMV D;  3DPT A;  1M5Q 1;  1XSZ A;  1VKL A;  3SNS A;  2Y8L A;  2O3O A;  2Z8U A;  1M3Q A;  2PWW A;  2YH5 A;  1LWW A;  2JPI A;  1HU0 A;  2ZFD B;  4CFF A;  4EAI A;  1YQR A;  3RPJ A;  2OOY A;  2LAE A;  2NVM A;  3OH9 A;  1JDY A;  4D7R A;  1QN7 A;  3T4N A;  1D3U A;  1QTP A;  2NOE A;  1TUO A;  1QNB A;  1KO9 A;  3ASM A;  3HS9 A;  3OCI A;  1WJW A;  1NH2 A;  1C47 A;  2H4L X;  4ROC B; 
#chains in the Genus database with same CATH homology
 2Y8Q A;  2QRD A;  2V8Q A;  1V5S A;  1UL7 A;  3TE5 A;  2OOX A;  2QRC A;  3OSE A;  4EAJ A;  2Y8L A;  2EHB D;  4EAL A;  2ZFD B;  4CFF A;  4EAI A;  2QR1 A;  2QRE A;  2OOY A;  2YA3 A;  3T4N A;  2QLV A;  4EAG A;  3TDH A;  2V9J A;  2V92 A;  4EAK A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4EAJA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization