4EAGA

Co-crystal structure of an chimeric ampk core with atp
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
125
structure length
98
Chain Sequence
AKWHLGIRSQSKPNDIMLEVYRAMKALSYEWKIINPYHVRVRRQNVKTGKFSKMSLQLYQVDAKSYLLDFKSLTLQPTGHHTMEFFEMCAALIIQLAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title AMP-activated protein kinase undergoes nucleotide-dependent conformational changes
pubmed doi rcsb
molecule tags Transferase
source organism Drosophila melanogaster
molecule keywords EG:132E8.2 protein
total genus 21
structure length 98
sequence length 125
ec nomenclature ec 2.7.11.-:
pdb deposition date 2012-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16579 AdenylateSensor Adenylate sensor of SNF1-like protein kinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 4eagA01
4EAKA 4EAGA 2Y8LA 3TDHA 2V9JA 2Y8QA 4EALA 2ZFDB 2YA3A 2OOXA 2QRCA 2QLVA 2EHBD 1V5SA 2V8QA 1UL7A 4EAJA 3OSEA 3T4NA 4EAIA 2QRDA 2V92A 4CFFA 2QR1A 2OOYA 3TE5A 2QREA
chains in the Genus database with same CATH superfamily
5JMVD 5AN4A 1C4GA 4TPSA 2HKPA 1MP9A 3SNSA 1QNCA 2H4LX 2F7LA 4I8OA 2JHJA 3OGDA 1KYUA 2XHIA 5F9CA 2Y8LA 3RSMA 4D7QA 3CVSA 1NGMA 2V9JA 2I5WA 1K2YX 3C04A 2DKCA 1YTFA 1FN7A 5IYBP 2EHBD 1V5SA 1XSZA 1TUOA 1MPGA 3OCIA 1HU0A 1VKLA 1W80A 3OSEA 3PMGA 2FKFA 3T4NA 1DIZA 1QTSA 1R4XA 1LWYA 1TGHA 1PVSA 2NOHA 4MRQA 4BJUA 4HJHA 2H5AX 2JOIA 3I0XA 3TE5A 4QG5A 1QNBA 1VOKA 2IV9A 5IYDP 3OH6A 4EAKA 4EAGA 2FGTA 1NVPA 2FUVA 1QN3A 3PDKA 1VTLE 4EJYA 2JHNA 2NOZA 1LWWA 1J3MA 3CVTA 1KY6A 3TDHA 3ULXA 2Y8QA 3IH7A 1N3AA 1K35A 4EALA 4EJZA 1NH2A 1AISA 1YQMA 2QLVA 2PWWA 3UW2A 2V8QA 1RM1A 3ENOC 4EAJA 2MJ7A 3HS9A 3BKQX 3F10A 3I3WA 3F0ZA 2HZSA 4ROEB 3OLPA 3OSMA 3KTUA 1KFIA 1YTBA 1YQKA 3EAYA 2NLVA 2QR1A 3EIKA 1P5DX 2D0AA 3OC3C 4C7PA 1LXTA 1QNAA 1VOLB 3HS8A 1QN9A 2IV8A 3OSTA 5IYCP 1PZDA 1WQAA 2LAEA 2D0BA 2O3OA 4ROCB 1E42A 1KO9A 1JDYA 2Z8UA 2HL8A 3ASMA 4WX8A 1D3UA 3DPTA 2FKMX 1KYFA 3DPUA 1N3CA 3N89A 4D7RA 2YA3A 2Z0FA 2QRCA 2MZ8A 1EUVA 4IL8A 1QN7A 1KFQA 5BMNA 3I0WA 1LWVA 1QN6A 1M5Q1 1QN4A 2DKAA 4EAIA 2V92A 1Q9UA 3VN5A 1KYDA 2NWVA 3KRMA 1M3QA 2NVMA 2NOFA 4Q11A 3D7QA 5EPCA 2VJ0A 2JPIA 2R5XA 1PCJX 1M3HA 1CDWA 4RODB 5JN5A 1C9BB 1T6AA 1QNEA 1VTOA 1C47A 1UT4A 3CWAA 1UT7A 2G30A 2YH5A 1JFIC 4WXAA 1YQLA 1PCZA 2NOIA 1EBMA 1QTPA 2HZMA 2HL9A 5KL0A 2NOBA 2ZFDB 3CW7A 1WJWA 2NOLA 3H1ZA 4B0AA 2OOXA 3RPJA 1UL7A 1PCMX 1TBPA 3CWSA 4DULA 1QN5A 3NA5A 2D0CA 1QN8A 2QRDA 4WZSD 4CFFA 2NOEA 3D4VA 1B9KA 1YQRA 3CWTA 4PY5A 2OOYA 2DKDA 3OH9A 5HSHA 3ENCA 2QREA 1N39A 5BMPA 1P5GX 1KY7A 3CWUA 1TBAB
chains in the Genus database with same CATH topology
4EAKA 4EAGA 2Y8LA 3TDHA 2V9JA 2Y8QA 4EALA 2ZFDB 2YA3A 2OOXA 2QRCA 2QLVA 2EHBD 1V5SA 2V8QA 1UL7A 4EAJA 3OSEA 3T4NA 4EAIA 2QRDA 2V92A 4CFFA 2QR1A 2OOYA 3TE5A 2QREA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EAK A;  4EAG A;  2Y8L A;  3TDH A;  2V9J A;  2Y8Q A;  4EAL A;  2ZFD B;  2YA3 A;  2OOX A;  2QRC A;  2QLV A;  2EHB D;  1V5S A;  2V8Q A;  1UL7 A;  4EAJ A;  3OSE A;  3T4N A;  4EAI A;  2QRD A;  2V92 A;  4CFF A;  2QR1 A;  2OOY A;  3TE5 A;  2QRE A; 
#chains in the Genus database with same CATH topology
 5JMV D;  5AN4 A;  1C4G A;  4TPS A;  2HKP A;  1MP9 A;  3SNS A;  1QNC A;  2H4L X;  2F7L A;  4I8O A;  2JHJ A;  3OGD A;  1KYU A;  2XHI A;  5F9C A;  2Y8L A;  3RSM A;  4D7Q A;  3CVS A;  1NGM A;  2V9J A;  2I5W A;  1K2Y X;  3C04 A;  2DKC A;  1YTF A;  1FN7 A;  5IYB P;  2EHB D;  1V5S A;  1XSZ A;  1TUO A;  1MPG A;  3OCI A;  1HU0 A;  1VKL A;  1W80 A;  3OSE A;  3PMG A;  2FKF A;  3T4N A;  1DIZ A;  1QTS A;  1R4X A;  1LWY A;  1TGH A;  1PVS A;  2NOH A;  4MRQ A;  4BJU A;  4HJH A;  2H5A X;  2JOI A;  3I0X A;  3TE5 A;  4QG5 A;  1QNB A;  1VOK A;  2IV9 A;  5IYD P;  3OH6 A;  4EAK A;  4EAG A;  2FGT A;  1NVP A;  2FUV A;  1QN3 A;  3PDK A;  1VTL E;  4EJY A;  2JHN A;  2NOZ A;  1LWW A;  1J3M A;  3CVT A;  1KY6 A;  3TDH A;  3ULX A;  2Y8Q A;  3IH7 A;  1N3A A;  1K35 A;  4EAL A;  4EJZ A;  1NH2 A;  1AIS A;  1YQM A;  2QLV A;  2PWW A;  3UW2 A;  2V8Q A;  1RM1 A;  3ENO C;  4EAJ A;  2MJ7 A;  3HS9 A;  3BKQ X;  3F10 A;  3I3W A;  3F0Z A;  2HZS A;  4ROE B;  3OLP A;  3OSM A;  3KTU A;  1KFI A;  1YTB A;  1YQK A;  3EAY A;  2NLV A;  2QR1 A;  3EIK A;  1P5D X;  2D0A A;  3OC3 C;  4C7P A;  1LXT A;  1QNA A;  1VOL B;  3HS8 A;  1QN9 A;  2IV8 A;  3OST A;  5IYC P;  1PZD A;  1WQA A;  2LAE A;  2D0B A;  2O3O A;  4ROC B;  1E42 A;  1KO9 A;  1JDY A;  2Z8U A;  2HL8 A;  3ASM A;  4WX8 A;  1D3U A;  3DPT A;  2FKM X;  1KYF A;  3DPU A;  1N3C A;  3N89 A;  4D7R A;  2YA3 A;  2Z0F A;  2QRC A;  2MZ8 A;  1EUV A;  4IL8 A;  1QN7 A;  1KFQ A;  5BMN A;  3I0W A;  1LWV A;  1QN6 A;  1M5Q 1;  1QN4 A;  2DKA A;  4EAI A;  2V92 A;  1Q9U A;  3VN5 A;  1KYD A;  2NWV A;  3KRM A;  1M3Q A;  2NVM A;  2NOF A;  4Q11 A;  3D7Q A;  5EPC A;  2VJ0 A;  2JPI A;  2R5X A;  1PCJ X;  1M3H A;  1CDW A;  4ROD B;  5JN5 A;  1C9B B;  1T6A A;  1QNE A;  1VTO A;  1C47 A;  1UT4 A;  3CWA A;  1UT7 A;  2G30 A;  2YH5 A;  1JFI C;  4WXA A;  1YQL A;  1PCZ A;  2NOI A;  1EBM A;  1QTP A;  2HZM A;  2HL9 A;  5KL0 A;  2NOB A;  2ZFD B;  3CW7 A;  1WJW A;  2NOL A;  3H1Z A;  4B0A A;  2OOX A;  3RPJ A;  1UL7 A;  1PCM X;  1TBP A;  3CWS A;  4DUL A;  1QN5 A;  3NA5 A;  2D0C A;  1QN8 A;  2QRD A;  4WZS D;  4CFF A;  2NOE A;  3D4V A;  1B9K A;  1YQR A;  3CWT A;  4PY5 A;  2OOY A;  2DKD A;  3OH9 A;  5HSH A;  3ENC A;  2QRE A;  1N39 A;  5BMP A;  1P5G X;  1KY7 A;  3CWU A;  1TBA B; 
#chains in the Genus database with same CATH homology
 4EAK A;  4EAG A;  2Y8L A;  3TDH A;  2V9J A;  2Y8Q A;  4EAL A;  2ZFD B;  2YA3 A;  2OOX A;  2QRC A;  2QLV A;  2EHB D;  1V5S A;  2V8Q A;  1UL7 A;  4EAJ A;  3OSE A;  3T4N A;  4EAI A;  2QRD A;  2V92 A;  4CFF A;  2QR1 A;  2OOY A;  3TE5 A;  2QRE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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