5IYCP

Human core-pic in the initial transcribing state
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
185
structure length
185
Chain Sequence
TPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
molecule tags Transcription, transferase/dna
source organism Homo sapiens
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 44
structure length 185
sequence length 185
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
P PF00352 TBP Transcription factor TFIID (or TATA-binding protein, TBP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 5iycP01
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 5iycP02
3EIKA 4WZSD 4ROCB 1KYDA 1PZDA 1QN5A 1VOLB 1QN6A 1VOKA 1QNCA 1R4XA 1NVPA 1PCZA 1QNBA 1QNEA 2D0AA 2D0CA 3OCIA 1AISA 3HS8A 4PY5A 1KY7A 1W80A 4ROEB 1NH2A 1JFIC 4B0AA 4RODB 2MJ7A 1D3UA 1YTBA 5IYBP 1TGHA 1YTFA 1QN9A 1QTPA 3VN5A 1QTSA 1QN7A 2Z8UA 1KYFA 1TBPA 3OC3C 1RM1A 1CDWA 1VTLE 5IYDP 1QN4A 1B9KA 1VTOA 2G30A 1C9BB 1QN8A 1E42A 1MP9A 2D0BA 1KY6A 2VJ0A 5IYCP 3H1ZA 1QN3A 3ASMA 3HS9A 1NGMA 2IV8A 1QNAA 2IV9A 1TBAB 1KYUA
chains in the Genus database with same CATH superfamily
3OGDA 1T6AA 4WZSD 1PZDA 4WXAA 2FKFA 5JMVD 1VOKA 3F0ZA 3DPUA 3I0XA 2FGTA 4BJUA 1QNEA 1J3MA 2I5WA 2NVMA 3HS8A 2Z0FA 1N3CA 4PY5A 2HL8A 4EAJA 5F9CA 1FN7A 4RODB 1TGHA 3CW7A 2DKAA 3F10A 3OSTA 1QTSA 1KYFA 1TBPA 2HZSA 2H5AX 1Q9UA 1K2YX 1M5Q1 3OC3C 4EJYA 1B9KA 1VTOA 3UW2A 2G30A 1C9BB 1QN8A 2MZ8A 4EJZA 3RSMA 1MPGA 1EUVA 1V5SA 2QR1A 3BKQX 3H1ZA 1QN3A 5JN5A 2O3OA 4D7RA 2R5XA 3HS9A 1KYUA 1C4GA 1NGMA 3EIKA 3EAYA 1TUOA 1QN6A 2JOIA 3CWUA 1QNCA 1UT4A 1PCZA 2NOEA 1LWYA 2NOLA 1LXTA 3CVTA 1PVSA 3KRMA 2F7LA 2HZMA 3C04A 4B0AA 2OOXA 3TDHA 1LWVA 5HSHA 3CVSA 3VN5A 1CDWA 5IYDP 2Y8LA 3PMGA 2H4LX 2D0BA 1N39A 1PCJX 2FUVA 1C47A 3SNSA 3ULXA 1DIZA 1UL7A 2NOIA 2IV8A 1QNAA 4EAGA 2V8QA 2JHNA 1W80A 1TBAB 1NH2A 3IH7A 3OLPA 4ROCB 1KYDA 3OH9A 3D4VA 2NOZA 1WQAA 2JPIA 4Q11A 2NLVA 4EAKA 2XHIA 3CWAA 1NVPA 1QNBA 1M3QA 1PCMX 2D0AA 2D0CA 3OCIA 1AISA 1KFQA 2NWVA 1KY7A 4ROEB 2V9JA 5BMNA 1YQKA 1N3AA 2QREA 1D3UA 1VKLA 1YQLA 3ENOC 3OSMA 5IYBP 1YTBA 1YTFA 2HL9A 1QN9A 2ZFDB 1QTPA 4IL8A 2Z8UA 5BMPA 4QG5A 1K35A 2HKPA 1VTLE 4C7PA 1QN4A 3NA5A 2DKDA 3DPTA 3OSEA 1P5GX 2VJ0A 1UT7A 1KFIA 2OOYA 3D7QA 1EBMA 4EALA 3ENCA 3CWSA 4D7QA 2YH5A 2IV9A 2Y8QA 5EPCA 5KL0A 4DULA 3CWTA 1VOLB 1QN5A 4MRQA 1R4XA 5AN4A 1JDYA 4CFFA 1M3HA 2LAEA 3I0WA 2YA3A 2NOHA 2NOBA 1JFIC 1XSZA 1WJWA 2DKCA 1KO9A 4TPSA 2NOFA 2MJ7A 2FKMX 1YQMA 1YQRA 3OH6A 3PDKA 4WX8A 2V92A 3TE5A 2QRCA 1QN7A 1RM1A 2EHBD 3KTUA 3I3WA 1LWWA 1E42A 3N89A 4EAIA 1MP9A 2PWWA 1KY6A 3RPJA 5IYCP 1HU0A 3ASMA 2JHJA 4HJHA 2QLVA 1P5DX 4I8OA 3T4NA 2QRDA
chains in the Genus database with same CATH topology
4WZSD 1PZDA 1VOKA 3F0ZA 3DPUA 3I0XA 2FGTA 1QNEA 2I5WA 3HS8A 4PY5A 1N3CA 1FN7A 4RODB 1TGHA 3F10A 3OSTA 1QTSA 1KYFA 1TBPA 2HZSA 3OC3C 4EJYA 1B9KA 1VTOA 2G30A 1C9BB 1QN8A 2MZ8A 4EJZA 3H1ZA 1QN3A 2O3OA 3HS9A 1NGMA 1KYUA 3EIKA 1QN6A 2JOIA 1QNCA 1UT4A 1PCZA 2NOEA 1LWYA 2NOLA 3KRMA 2HZMA 4B0AA 1LWVA 3VN5A 1CDWA 5IYDP 2D0BA 1N39A 3SNSA 3ULXA 2NOIA 2IV8A 1QNAA 1W80A 1TBAB 1NH2A 3IH7A 4ROCB 1KYDA 2NOZA 4Q11A 2XHIA 1NVPA 1QNBA 1M3QA 2D0AA 2D0CA 3OCIA 1AISA 1KY7A 4ROEB 1YQKA 1N3AA 1D3UA 1YTBA 1YQLA 3OSMA 5IYBP 1YTFA 1QN9A 1QTPA 2Z8UA 1VTLE 1QN4A 3DPTA 2VJ0A 1UT7A 1EBMA 2YH5A 2IV9A 4DULA 1VOLB 1QN5A 1R4XA 5AN4A 1M3HA 2LAEA 3I0WA 2NOHA 2NOBA 1JFIC 1KO9A 4TPSA 2NOFA 2MJ7A 1YQMA 1YQRA 1QN7A 1RM1A 3KTUA 1LWWA 1E42A 3N89A 1MP9A 1KY6A 3RPJA 5IYCP 1HU0A 3ASMA 4I8OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EIK A;  4WZS D;  4ROC B;  1KYD A;  1PZD A;  1QN5 A;  1VOL B;  1QN6 A;  1VOK A;  1QNC A;  1R4X A;  1NVP A;  1PCZ A;  1QNB A;  1QNE A;  2D0A A;  2D0C A;  3OCI A;  1AIS A;  3HS8 A;  4PY5 A;  1KY7 A;  1W80 A;  4ROE B;  1NH2 A;  1JFI C;  4B0A A;  4ROD B;  2MJ7 A;  1D3U A;  1YTB A;  5IYB P;  1TGH A;  1YTF A;  1QN9 A;  1QTP A;  3VN5 A;  1QTS A;  1QN7 A;  2Z8U A;  1KYF A;  1TBP A;  3OC3 C;  1RM1 A;  1CDW A;  1VTL E;  5IYD P;  1QN4 A;  1B9K A;  1VTO A;  2G30 A;  1C9B B;  1QN8 A;  1E42 A;  1MP9 A;  2D0B A;  1KY6 A;  2VJ0 A;  5IYC P;  3H1Z A;  1QN3 A;  3ASM A;  3HS9 A;  1NGM A;  2IV8 A;  1QNA A;  2IV9 A;  1TBA B;  1KYU A; 
#chains in the Genus database with same CATH topology
 3OGD A;  1T6A A;  4WZS D;  1PZD A;  4WXA A;  2FKF A;  5JMV D;  1VOK A;  3F0Z A;  3DPU A;  3I0X A;  2FGT A;  4BJU A;  1QNE A;  1J3M A;  2I5W A;  2NVM A;  3HS8 A;  2Z0F A;  1N3C A;  4PY5 A;  2HL8 A;  4EAJ A;  5F9C A;  1FN7 A;  4ROD B;  1TGH A;  3CW7 A;  2DKA A;  3F10 A;  3OST A;  1QTS A;  1KYF A;  1TBP A;  2HZS A;  2H5A X;  1Q9U A;  1K2Y X;  1M5Q 1;  3OC3 C;  4EJY A;  1B9K A;  1VTO A;  3UW2 A;  2G30 A;  1C9B B;  1QN8 A;  2MZ8 A;  4EJZ A;  3RSM A;  1MPG A;  1EUV A;  1V5S A;  2QR1 A;  3BKQ X;  3H1Z A;  1QN3 A;  5JN5 A;  2O3O A;  4D7R A;  2R5X A;  3HS9 A;  1KYU A;  1C4G A;  1NGM A;  3EIK A;  3EAY A;  1TUO A;  1QN6 A;  2JOI A;  3CWU A;  1QNC A;  1UT4 A;  1PCZ A;  2NOE A;  1LWY A;  2NOL A;  1LXT A;  3CVT A;  1PVS A;  3KRM A;  2F7L A;  2HZM A;  3C04 A;  4B0A A;  2OOX A;  3TDH A;  1LWV A;  5HSH A;  3CVS A;  3VN5 A;  1CDW A;  5IYD P;  2Y8L A;  3PMG A;  2H4L X;  2D0B A;  1N39 A;  1PCJ X;  2FUV A;  1C47 A;  3SNS A;  3ULX A;  1DIZ A;  1UL7 A;  2NOI A;  2IV8 A;  1QNA A;  4EAG A;  2V8Q A;  2JHN A;  1W80 A;  1TBA B;  1NH2 A;  3IH7 A;  3OLP A;  4ROC B;  1KYD A;  3OH9 A;  3D4V A;  2NOZ A;  1WQA A;  2JPI A;  4Q11 A;  2NLV A;  4EAK A;  2XHI A;  3CWA A;  1NVP A;  1QNB A;  1M3Q A;  1PCM X;  2D0A A;  2D0C A;  3OCI A;  1AIS A;  1KFQ A;  2NWV A;  1KY7 A;  4ROE B;  2V9J A;  5BMN A;  1YQK A;  1N3A A;  2QRE A;  1D3U A;  1VKL A;  1YQL A;  3ENO C;  3OSM A;  5IYB P;  1YTB A;  1YTF A;  2HL9 A;  1QN9 A;  2ZFD B;  1QTP A;  4IL8 A;  2Z8U A;  5BMP A;  4QG5 A;  1K35 A;  2HKP A;  1VTL E;  4C7P A;  1QN4 A;  3NA5 A;  2DKD A;  3DPT A;  3OSE A;  1P5G X;  2VJ0 A;  1UT7 A;  1KFI A;  2OOY A;  3D7Q A;  1EBM A;  4EAL A;  3ENC A;  3CWS A;  4D7Q A;  2YH5 A;  2IV9 A;  2Y8Q A;  5EPC A;  5KL0 A;  4DUL A;  3CWT A;  1VOL B;  1QN5 A;  4MRQ A;  1R4X A;  5AN4 A;  1JDY A;  4CFF A;  1M3H A;  2LAE A;  3I0W A;  2YA3 A;  2NOH A;  2NOB A;  1JFI C;  1XSZ A;  1WJW A;  2DKC A;  1KO9 A;  4TPS A;  2NOF A;  2MJ7 A;  2FKM X;  1YQM A;  1YQR A;  3OH6 A;  3PDK A;  4WX8 A;  2V92 A;  3TE5 A;  2QRC A;  1QN7 A;  1RM1 A;  2EHB D;  3KTU A;  3I3W A;  1LWW A;  1E42 A;  3N89 A;  4EAI A;  1MP9 A;  2PWW A;  1KY6 A;  3RPJ A;  5IYC P;  1HU0 A;  3ASM A;  2JHJ A;  4HJH A;  2QLV A;  1P5D X;  4I8O A;  3T4N A;  2QRD A; 
#chains in the Genus database with same CATH homology
 4WZS D;  1PZD A;  1VOK A;  3F0Z A;  3DPU A;  3I0X A;  2FGT A;  1QNE A;  2I5W A;  3HS8 A;  4PY5 A;  1N3C A;  1FN7 A;  4ROD B;  1TGH A;  3F10 A;  3OST A;  1QTS A;  1KYF A;  1TBP A;  2HZS A;  3OC3 C;  4EJY A;  1B9K A;  1VTO A;  2G30 A;  1C9B B;  1QN8 A;  2MZ8 A;  4EJZ A;  3H1Z A;  1QN3 A;  2O3O A;  3HS9 A;  1NGM A;  1KYU A;  3EIK A;  1QN6 A;  2JOI A;  1QNC A;  1UT4 A;  1PCZ A;  2NOE A;  1LWY A;  2NOL A;  3KRM A;  2HZM A;  4B0A A;  1LWV A;  3VN5 A;  1CDW A;  5IYD P;  2D0B A;  1N39 A;  3SNS A;  3ULX A;  2NOI A;  2IV8 A;  1QNA A;  1W80 A;  1TBA B;  1NH2 A;  3IH7 A;  4ROC B;  1KYD A;  2NOZ A;  4Q11 A;  2XHI A;  1NVP A;  1QNB A;  1M3Q A;  2D0A A;  2D0C A;  3OCI A;  1AIS A;  1KY7 A;  4ROE B;  1YQK A;  1N3A A;  1D3U A;  1YTB A;  1YQL A;  3OSM A;  5IYB P;  1YTF A;  1QN9 A;  1QTP A;  2Z8U A;  1VTL E;  1QN4 A;  3DPT A;  2VJ0 A;  1UT7 A;  1EBM A;  2YH5 A;  2IV9 A;  4DUL A;  1VOL B;  1QN5 A;  1R4X A;  5AN4 A;  1M3H A;  2LAE A;  3I0W A;  2NOH A;  2NOB A;  1JFI C;  1KO9 A;  4TPS A;  2NOF A;  2MJ7 A;  1YQM A;  1YQR A;  1QN7 A;  1RM1 A;  3KTU A;  1LWW A;  1E42 A;  3N89 A;  1MP9 A;  1KY6 A;  3RPJ A;  5IYC P;  1HU0 A;  3ASM A;  4I8O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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