5IYCP

Human core-pic in the initial transcribing state
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
185
structure length
185
Chain Sequence
TPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
molecule tags Transcription, transferase/dna
source organism Homo sapiens
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 44
structure length 185
sequence length 185
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
P PF00352 TBP Transcription factor TFIID (or TATA-binding protein, TBP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 5iycP01
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 5iycP02
1QTSA 1VTOA 1QTPA 5IYBP 1VTLE 1PCZA 3OC3C 1QN3A 1QN9A 4PY5A 1QN5A 1QNBA 1TGHA 2Z8UA 1TBPA 1C9BB 1QN6A 1YTFA 3OCIA 2D0BA 1CDWA 1QNEA 1KY7A 1QN7A 1PZDA 1D3UA 1W80A 1VOLB 1YTBA 1E42A 2MJ7A 1VOKA 3ASMA 3H1ZA 1NH2A 2IV9A 1TBAB 1R4XA 2VJ0A 1AISA 1QN8A 1KYDA 1NVPA 1QNAA 1KYFA 3EIKA 2D0CA 2IV8A 1QN4A 1MP9A 1KYUA 1B9KA 3HS9A 4ROCB 4B0AA 4WZSD 5IYCP 1RM1A 1QNCA 5IYDP 1KY6A 2G30A 1JFIC 4RODB 2D0AA 1NGMA 4ROEB 3HS8A 3VN5A
chains in the Genus database with same CATH superfamily
1QTSA 5F9CA 4EAGA 1EBMA 4QG5A 1HU0A 4I8OA 1V5SA 3CVSA 1MPGA 2HL8A 2YH5A 5JMVD 1TGHA 2Z8UA 2Y8LA 1KFQA 3TE5A 1T6AA 2DKCA 2FKMX 3N89A 1N3CA 1QNEA 3CW7A 1M3HA 1W80A 2QLVA 1YTBA 2NOHA 3ENCA 1WJWA 1WQAA 2JPIA 3ASMA 1XSZA 3H1ZA 4CFFA 1C4GA 1R4XA 1PCJX 1QN8A 3CVTA 3F0ZA 1NVPA 1QNAA 1VKLA 3EIKA 1UT7A 4BJUA 2D0CA 1UL7A 1YQRA 2NOIA 4D7QA 1KYUA 2H4LX 3CWTA 2ZFDB 2NOLA 2V92A 4B0AA 1KY6A 2HKPA 3CWUA 2NOBA 2QRDA 3SNSA 5BMNA 1Q9UA 2OOYA 3VN5A 3OSEA 1DIZA 1PCZA 2QR1A 3OC3C 1LWWA 1QN3A 3NA5A 1TUOA 3I0XA 5JN5A 2YA3A 1QN7A 1PZDA 4EAJA 2OOXA 1JDYA 2NVMA 3OH9A 5BMPA 2NLVA 4MRQA 1VOKA 3OSTA 1KYDA 2FKFA 3OLPA 5HSHA 4D7RA 2V9JA 4EJZA 4IL8A 3HS9A 4WXAA 4DULA 1QNCA 1YQLA 2NWVA 1N3AA 2G30A 3D4VA 3F10A 3HS8A 1PVSA 3PMGA 3ULXA 4TPSA 1VTLE 1NGMA 1QTPA 1QN9A 1QN5A 1LWYA 1KO9A 3T4NA 2HL9A 3KTUA 1YTFA 3OCIA 1FN7A 2D0BA 3I3WA 1CDWA 2DKAA 2R5XA 4EAIA 5EPCA 2EHBD 3RPJA 2QREA 3OGDA 1VOLB 2HZMA 1E42A 1LWVA 2LAEA 3ENOC 4Q11A 1NH2A 2JHNA 1KYFA 2V8QA 3C04A 2O3OA 1MP9A 2NOFA 1B9KA 3CWSA 3DPUA 4ROCB 2JOIA 2PWWA 1P5GX 5IYDP 4EJYA 1JFIC 4RODB 2D0AA 1QNBA 4ROEB 3I0WA 3TDHA 1VTOA 5IYBP 1K2YX 1YQKA 4PY5A 2H5AX 4C7PA 1C47A 1TBPA 2HZSA 3PDKA 3IH7A 1C9BB 1QN6A 2NOEA 1P5DX 2XHIA 3BKQX 3OSMA 1KY7A 2FUVA 5AN4A 1D3UA 3RSMA 1N39A 2FGTA 2MJ7A 1AISA 2IV9A 1TBAB 2QRCA 2VJ0A 2Z0FA 3UW2A 1J3MA 4HJHA 5KL0A 1M5Q1 2I5WA 3EAYA 2Y8QA 3OH6A 1YQMA 2NOZA 2F7LA 2JHJA 1K35A 2IV8A 1QN4A 3CWAA 1PCMX 3DPTA 1UT4A 2DKDA 1LXTA 4WX8A 2MZ8A 1KFIA 4EALA 4WZSD 4EAKA 5IYCP 1RM1A 3D7QA 1EUVA 1M3QA 3KRMA
chains in the Genus database with same CATH topology
1QTSA 1EBMA 1HU0A 4I8OA 2YH5A 1TGHA 2Z8UA 3N89A 1N3CA 1QNEA 1M3HA 1W80A 1YTBA 2NOHA 3ASMA 3H1ZA 1QN8A 1R4XA 3F0ZA 1NVPA 1QNAA 3EIKA 1UT7A 2D0CA 1YQRA 2NOIA 1KYUA 2NOLA 4B0AA 1KY6A 2NOBA 3SNSA 3VN5A 1PCZA 3OC3C 1LWWA 1QN3A 3I0XA 1QN7A 1PZDA 1VOKA 3OSTA 1KYDA 4EJZA 3HS9A 4DULA 1QNCA 1YQLA 1N3AA 2G30A 3F10A 3HS8A 3ULXA 1NGMA 4TPSA 1VTLE 1QTPA 1QN9A 1QN5A 1LWYA 1KO9A 3KTUA 1YTFA 3OCIA 1FN7A 2D0BA 1CDWA 3RPJA 1VOLB 2HZMA 1E42A 1LWVA 2LAEA 4Q11A 1NH2A 1KYFA 2O3OA 1MP9A 2NOFA 1B9KA 3DPUA 4ROCB 2JOIA 5IYDP 4EJYA 1JFIC 4RODB 2D0AA 1QNBA 4ROEB 3I0WA 1VTOA 5IYBP 1YQKA 4PY5A 2HZSA 1TBPA 1C9BB 3IH7A 1QN6A 2NOEA 2XHIA 3OSMA 1KY7A 5AN4A 1D3UA 1N39A 2FGTA 2MJ7A 1AISA 2IV9A 1TBAB 2VJ0A 2I5WA 1YQMA 2NOZA 2IV8A 1QN4A 3DPTA 1UT4A 2MZ8A 4WZSD 5IYCP 1RM1A 1M3QA 3KRMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QTS A;  1VTO A;  1QTP A;  5IYB P;  1VTL E;  1PCZ A;  3OC3 C;  1QN3 A;  1QN9 A;  4PY5 A;  1QN5 A;  1QNB A;  1TGH A;  2Z8U A;  1TBP A;  1C9B B;  1QN6 A;  1YTF A;  3OCI A;  2D0B A;  1CDW A;  1QNE A;  1KY7 A;  1QN7 A;  1PZD A;  1D3U A;  1W80 A;  1VOL B;  1YTB A;  1E42 A;  2MJ7 A;  1VOK A;  3ASM A;  3H1Z A;  1NH2 A;  2IV9 A;  1TBA B;  1R4X A;  2VJ0 A;  1AIS A;  1QN8 A;  1KYD A;  1NVP A;  1QNA A;  1KYF A;  3EIK A;  2D0C A;  2IV8 A;  1QN4 A;  1MP9 A;  1KYU A;  1B9K A;  3HS9 A;  4ROC B;  4B0A A;  4WZS D;  5IYC P;  1RM1 A;  1QNC A;  5IYD P;  1KY6 A;  2G30 A;  1JFI C;  4ROD B;  2D0A A;  1NGM A;  4ROE B;  3HS8 A;  3VN5 A; 
#chains in the Genus database with same CATH topology
 1QTS A;  5F9C A;  4EAG A;  1EBM A;  4QG5 A;  1HU0 A;  4I8O A;  1V5S A;  3CVS A;  1MPG A;  2HL8 A;  2YH5 A;  5JMV D;  1TGH A;  2Z8U A;  2Y8L A;  1KFQ A;  3TE5 A;  1T6A A;  2DKC A;  2FKM X;  3N89 A;  1N3C A;  1QNE A;  3CW7 A;  1M3H A;  1W80 A;  2QLV A;  1YTB A;  2NOH A;  3ENC A;  1WJW A;  1WQA A;  2JPI A;  3ASM A;  1XSZ A;  3H1Z A;  4CFF A;  1C4G A;  1R4X A;  1PCJ X;  1QN8 A;  3CVT A;  3F0Z A;  1NVP A;  1QNA A;  1VKL A;  3EIK A;  1UT7 A;  4BJU A;  2D0C A;  1UL7 A;  1YQR A;  2NOI A;  4D7Q A;  1KYU A;  2H4L X;  3CWT A;  2ZFD B;  2NOL A;  2V92 A;  4B0A A;  1KY6 A;  2HKP A;  3CWU A;  2NOB A;  2QRD A;  3SNS A;  5BMN A;  1Q9U A;  2OOY A;  3VN5 A;  3OSE A;  1DIZ A;  1PCZ A;  2QR1 A;  3OC3 C;  1LWW A;  1QN3 A;  3NA5 A;  1TUO A;  3I0X A;  5JN5 A;  2YA3 A;  1QN7 A;  1PZD A;  4EAJ A;  2OOX A;  1JDY A;  2NVM A;  3OH9 A;  5BMP A;  2NLV A;  4MRQ A;  1VOK A;  3OST A;  1KYD A;  2FKF A;  3OLP A;  5HSH A;  4D7R A;  2V9J A;  4EJZ A;  4IL8 A;  3HS9 A;  4WXA A;  4DUL A;  1QNC A;  1YQL A;  2NWV A;  1N3A A;  2G30 A;  3D4V A;  3F10 A;  3HS8 A;  1PVS A;  3PMG A;  3ULX A;  4TPS A;  1VTL E;  1NGM A;  1QTP A;  1QN9 A;  1QN5 A;  1LWY A;  1KO9 A;  3T4N A;  2HL9 A;  3KTU A;  1YTF A;  3OCI A;  1FN7 A;  2D0B A;  3I3W A;  1CDW A;  2DKA A;  2R5X A;  4EAI A;  5EPC A;  2EHB D;  3RPJ A;  2QRE A;  3OGD A;  1VOL B;  2HZM A;  1E42 A;  1LWV A;  2LAE A;  3ENO C;  4Q11 A;  1NH2 A;  2JHN A;  1KYF A;  2V8Q A;  3C04 A;  2O3O A;  1MP9 A;  2NOF A;  1B9K A;  3CWS A;  3DPU A;  4ROC B;  2JOI A;  2PWW A;  1P5G X;  5IYD P;  4EJY A;  1JFI C;  4ROD B;  2D0A A;  1QNB A;  4ROE B;  3I0W A;  3TDH A;  1VTO A;  5IYB P;  1K2Y X;  1YQK A;  4PY5 A;  2H5A X;  4C7P A;  1C47 A;  1TBP A;  2HZS A;  3PDK A;  3IH7 A;  1C9B B;  1QN6 A;  2NOE A;  1P5D X;  2XHI A;  3BKQ X;  3OSM A;  1KY7 A;  2FUV A;  5AN4 A;  1D3U A;  3RSM A;  1N39 A;  2FGT A;  2MJ7 A;  1AIS A;  2IV9 A;  1TBA B;  2QRC A;  2VJ0 A;  2Z0F A;  3UW2 A;  1J3M A;  4HJH A;  5KL0 A;  1M5Q 1;  2I5W A;  3EAY A;  2Y8Q A;  3OH6 A;  1YQM A;  2NOZ A;  2F7L A;  2JHJ A;  1K35 A;  2IV8 A;  1QN4 A;  3CWA A;  1PCM X;  3DPT A;  1UT4 A;  2DKD A;  1LXT A;  4WX8 A;  2MZ8 A;  1KFI A;  4EAL A;  4WZS D;  4EAK A;  5IYC P;  1RM1 A;  3D7Q A;  1EUV A;  1M3Q A;  3KRM A; 
#chains in the Genus database with same CATH homology
 1QTS A;  1EBM A;  1HU0 A;  4I8O A;  2YH5 A;  1TGH A;  2Z8U A;  3N89 A;  1N3C A;  1QNE A;  1M3H A;  1W80 A;  1YTB A;  2NOH A;  3ASM A;  3H1Z A;  1QN8 A;  1R4X A;  3F0Z A;  1NVP A;  1QNA A;  3EIK A;  1UT7 A;  2D0C A;  1YQR A;  2NOI A;  1KYU A;  2NOL A;  4B0A A;  1KY6 A;  2NOB A;  3SNS A;  3VN5 A;  1PCZ A;  3OC3 C;  1LWW A;  1QN3 A;  3I0X A;  1QN7 A;  1PZD A;  1VOK A;  3OST A;  1KYD A;  4EJZ A;  3HS9 A;  4DUL A;  1QNC A;  1YQL A;  1N3A A;  2G30 A;  3F10 A;  3HS8 A;  3ULX A;  1NGM A;  4TPS A;  1VTL E;  1QTP A;  1QN9 A;  1QN5 A;  1LWY A;  1KO9 A;  3KTU A;  1YTF A;  3OCI A;  1FN7 A;  2D0B A;  1CDW A;  3RPJ A;  1VOL B;  2HZM A;  1E42 A;  1LWV A;  2LAE A;  4Q11 A;  1NH2 A;  1KYF A;  2O3O A;  1MP9 A;  2NOF A;  1B9K A;  3DPU A;  4ROC B;  2JOI A;  5IYD P;  4EJY A;  1JFI C;  4ROD B;  2D0A A;  1QNB A;  4ROE B;  3I0W A;  1VTO A;  5IYB P;  1YQK A;  4PY5 A;  2HZS A;  1TBP A;  1C9B B;  3IH7 A;  1QN6 A;  2NOE A;  2XHI A;  3OSM A;  1KY7 A;  5AN4 A;  1D3U A;  1N39 A;  2FGT A;  2MJ7 A;  1AIS A;  2IV9 A;  1TBA B;  2VJ0 A;  2I5W A;  1YQM A;  2NOZ A;  2IV8 A;  1QN4 A;  3DPT A;  1UT4 A;  2MZ8 A;  4WZS D;  5IYC P;  1RM1 A;  1M3Q A;  3KRM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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