5IYBP

Human core-pic in the open state
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
185
structure length
185
Chain Sequence
TPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
molecule tags Transcription, transferase/dna
source organism Homo sapiens
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 43
structure length 185
sequence length 185
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
P PF00352 TBP Transcription factor TFIID (or TATA-binding protein, TBP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 5iybP01
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 5iybP02
1PZDA 4RODB 2IV8A 1QNEA 1QNAA 1QNCA 1KYFA 1C9BB 1VTLE 1VOKA 1QNBA 1KYUA 1QN3A 1KY6A 1NGMA 1PCZA 1TBPA 2MJ7A 1QN8A 3OCIA 5IYCP 1NVPA 1QN9A 1QN4A 1QN7A 5IYDP 2D0CA 1NH2A 1B9KA 1CDWA 1QN6A 3EIKA 4PY5A 1QTSA 1R4XA 1QTPA 4B0AA 4WZSD 1JFIC 3H1ZA 3HS8A 1YTBA 3VN5A 2D0AA 2IV9A 3OC3C 5IYBP 3ASMA 1VOLB 1TBAB 1RM1A 3HS9A 4ROEB 1E42A 1KY7A 1AISA 2Z8UA 2D0BA 4ROCB 1VTOA 1YTFA 1KYDA 1TGHA 1QN5A 1W80A 1MP9A 1D3UA 2G30A 2VJ0A
chains in the Genus database with same CATH superfamily
4RODB 2IV8A 3F0ZA 4WX8A 1K35A 1QNAA 2NOZA 2H4LX 5KL0A 3CWAA 2QRDA 2F7LA 2V92A 3OSEA 1VTLE 2EHBD 2FKMX 1KYUA 2V9JA 1QN3A 3I0XA 2O3OA 1XSZA 4WXAA 3TDHA 3OCIA 3TE5A 5IYCP 1QN8A 1WQAA 4C7PA 2NOHA 4MRQA 3BKQX 4PY5A 2PWWA 3D7QA 3N89A 5EPCA 2HL9A 3VN5A 1JDYA 4EAJA 3CWUA 1LWVA 2HL8A 2NOBA 1RM1A 2Y8LA 1T6AA 1KY7A 4EJYA 3ULXA 1Q9UA 1KFIA 1EBMA 2NOFA 4ROCB 3OH6A 1TGHA 2JPIA 3OLPA 4D7RA 1W80A 2XHIA 1M3QA 2FKFA 2NWVA 3CW7A 2I5WA 1PVSA 2DKDA 2V8QA 1QNCA 2FGTA 2HZSA 2QLVA 1KYFA 3I0WA 3ENCA 3CWSA 4EAKA 3OSTA 5F9CA 3KTUA 1NGMA 1QN4A 3PMGA 3UW2A 2D0CA 1QN6A 1B9KA 4CFFA 1HU0A 3ENOC 1JFIC 3NA5A 4BJUA 1YTBA 1J3MA 2IV9A 3OC3C 3ASMA 1N3CA 1TBAB 4EALA 4ROEB 1UT7A 1AISA 3CWTA 1WJWA 1KFQA 3OH9A 4IL8A 3T4NA 4DULA 1QN5A 1PCJX 1TUOA 2G30A 3KRMA 2VJ0A 2ZFDB 2LAEA 1KO9A 2YA3A 4EJZA 1QNEA 2MZ8A 2JHNA 2QRCA 3F10A 1VOKA 2Z0FA 1K2YX 3I3WA 1KY6A 3PDKA 4Q11A 1PCZA 3OGDA 1UL7A 2H5AX 1NVPA 1FN7A 1QN9A 1QN7A 2OOYA 4I8OA 1NH2A 3C04A 2HZMA 1CDWA 3EIKA 1QTSA 1R4XA 4WZSD 3H1ZA 3HS8A 5IYBP 1UT4A 1LWYA 1VOLB 3HS9A 4EAGA 3CVTA 3SNSA 1VTOA 1KYDA 1M3HA 1YQRA 1LWWA 3DPUA 3EAYA 1YQLA 1YQMA 1N39A 2NOIA 5AN4A 1PZDA 1C47A 1N3AA 1PCMX 2JHJA 2OOXA 2Y8QA 4QG5A 3D4VA 1V5SA 3RPJA 2NOEA 1C9BB 3OSMA 5HSHA 4D7QA 1QNBA 1MPGA 1TBPA 2MJ7A 5IYDP 1LXTA 2YH5A 2NLVA 2R5XA 2JOIA 4EAIA 4HJHA 2DKCA 1QTPA 4B0AA 5BMPA 1DIZA 1P5GX 2D0AA 2DKAA 2HKPA 2QR1A 1YQKA 1E42A 1VKLA 3DPTA 3CVSA 2NVMA 2Z8UA 1EUVA 2D0BA 4TPSA 1YTFA 5JMVD 5BMNA 1M5Q1 2FUVA 3IH7A 1MP9A 2QREA 1D3UA 1C4GA 2NOLA 3RSMA 1P5DX 5JN5A
chains in the Genus database with same CATH topology
4RODB 2IV8A 3F0ZA 1QNAA 2NOZA 1VTLE 1QN3A 1KYUA 3I0XA 2O3OA 1QN8A 3OCIA 5IYCP 2NOHA 4PY5A 3N89A 3VN5A 1LWVA 2NOBA 1RM1A 1KY7A 4EJYA 3ULXA 1EBMA 2NOFA 4ROCB 1TGHA 2XHIA 1W80A 1M3QA 2I5WA 1QNCA 2FGTA 2HZSA 1KYFA 3I0WA 3OSTA 3KTUA 1NGMA 1QN4A 2D0CA 1QN6A 1B9KA 1HU0A 1JFIC 1YTBA 2IV9A 3OC3C 3ASMA 1N3CA 1TBAB 4ROEB 1UT7A 1AISA 4DULA 1QN5A 2G30A 3KRMA 2VJ0A 2LAEA 1KO9A 4EJZA 1QNEA 2MZ8A 3F10A 1VOKA 1KY6A 4Q11A 1PCZA 1NVPA 1FN7A 1QN9A 1QN7A 4I8OA 1NH2A 1CDWA 2HZMA 3EIKA 1QTSA 1R4XA 4WZSD 3H1ZA 3HS8A 5IYBP 1UT4A 1LWYA 1VOLB 3HS9A 3SNSA 1VTOA 1KYDA 1M3HA 1YQRA 1LWWA 3DPUA 1YQLA 1N39A 1YQMA 2NOIA 5AN4A 1PZDA 1N3AA 3RPJA 2NOEA 1C9BB 3OSMA 1QNBA 1TBPA 2MJ7A 5IYDP 2YH5A 2JOIA 4B0AA 1QTPA 2D0AA 1YQKA 1E42A 3DPTA 2Z8UA 2D0BA 4TPSA 1YTFA 3IH7A 1MP9A 2NOLA 1D3UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PZD A;  4ROD B;  2IV8 A;  1QNE A;  1QNA A;  1QNC A;  1KYF A;  1C9B B;  1VTL E;  1VOK A;  1QNB A;  1KYU A;  1QN3 A;  1KY6 A;  1NGM A;  1PCZ A;  1TBP A;  2MJ7 A;  1QN8 A;  3OCI A;  5IYC P;  1NVP A;  1QN9 A;  1QN4 A;  1QN7 A;  5IYD P;  2D0C A;  1NH2 A;  1B9K A;  1CDW A;  1QN6 A;  3EIK A;  4PY5 A;  1QTS A;  1R4X A;  1QTP A;  4B0A A;  4WZS D;  1JFI C;  3H1Z A;  3HS8 A;  1YTB A;  3VN5 A;  2D0A A;  2IV9 A;  3OC3 C;  5IYB P;  3ASM A;  1VOL B;  1TBA B;  1RM1 A;  3HS9 A;  4ROE B;  1E42 A;  1KY7 A;  1AIS A;  2Z8U A;  2D0B A;  4ROC B;  1VTO A;  1YTF A;  1KYD A;  1TGH A;  1QN5 A;  1W80 A;  1MP9 A;  1D3U A;  2G30 A;  2VJ0 A; 
#chains in the Genus database with same CATH topology
 4ROD B;  2IV8 A;  3F0Z A;  4WX8 A;  1K35 A;  1QNA A;  2NOZ A;  2H4L X;  5KL0 A;  3CWA A;  2QRD A;  2F7L A;  2V92 A;  3OSE A;  1VTL E;  2EHB D;  2FKM X;  1KYU A;  2V9J A;  1QN3 A;  3I0X A;  2O3O A;  1XSZ A;  4WXA A;  3TDH A;  3OCI A;  3TE5 A;  5IYC P;  1QN8 A;  1WQA A;  4C7P A;  2NOH A;  4MRQ A;  3BKQ X;  4PY5 A;  2PWW A;  3D7Q A;  3N89 A;  5EPC A;  2HL9 A;  3VN5 A;  1JDY A;  4EAJ A;  3CWU A;  1LWV A;  2HL8 A;  2NOB A;  1RM1 A;  2Y8L A;  1T6A A;  1KY7 A;  4EJY A;  3ULX A;  1Q9U A;  1KFI A;  1EBM A;  2NOF A;  4ROC B;  3OH6 A;  1TGH A;  2JPI A;  3OLP A;  4D7R A;  1W80 A;  2XHI A;  1M3Q A;  2FKF A;  2NWV A;  3CW7 A;  2I5W A;  1PVS A;  2DKD A;  2V8Q A;  1QNC A;  2FGT A;  2HZS A;  2QLV A;  1KYF A;  3I0W A;  3ENC A;  3CWS A;  4EAK A;  3OST A;  5F9C A;  3KTU A;  1NGM A;  1QN4 A;  3PMG A;  3UW2 A;  2D0C A;  1QN6 A;  1B9K A;  4CFF A;  1HU0 A;  3ENO C;  1JFI C;  3NA5 A;  4BJU A;  1YTB A;  1J3M A;  2IV9 A;  3OC3 C;  3ASM A;  1N3C A;  1TBA B;  4EAL A;  4ROE B;  1UT7 A;  1AIS A;  3CWT A;  1WJW A;  1KFQ A;  3OH9 A;  4IL8 A;  3T4N A;  4DUL A;  1QN5 A;  1PCJ X;  1TUO A;  2G30 A;  3KRM A;  2VJ0 A;  2ZFD B;  2LAE A;  1KO9 A;  2YA3 A;  4EJZ A;  1QNE A;  2MZ8 A;  2JHN A;  2QRC A;  3F10 A;  1VOK A;  2Z0F A;  1K2Y X;  3I3W A;  1KY6 A;  3PDK A;  4Q11 A;  1PCZ A;  3OGD A;  1UL7 A;  2H5A X;  1NVP A;  1FN7 A;  1QN9 A;  1QN7 A;  2OOY A;  4I8O A;  1NH2 A;  3C04 A;  2HZM A;  1CDW A;  3EIK A;  1QTS A;  1R4X A;  4WZS D;  3H1Z A;  3HS8 A;  5IYB P;  1UT4 A;  1LWY A;  1VOL B;  3HS9 A;  4EAG A;  3CVT A;  3SNS A;  1VTO A;  1KYD A;  1M3H A;  1YQR A;  1LWW A;  3DPU A;  3EAY A;  1YQL A;  1YQM A;  1N39 A;  2NOI A;  5AN4 A;  1PZD A;  1C47 A;  1N3A A;  1PCM X;  2JHJ A;  2OOX A;  2Y8Q A;  4QG5 A;  3D4V A;  1V5S A;  3RPJ A;  2NOE A;  1C9B B;  3OSM A;  5HSH A;  4D7Q A;  1QNB A;  1MPG A;  1TBP A;  2MJ7 A;  5IYD P;  1LXT A;  2YH5 A;  2NLV A;  2R5X A;  2JOI A;  4EAI A;  4HJH A;  2DKC A;  1QTP A;  4B0A A;  5BMP A;  1DIZ A;  1P5G X;  2D0A A;  2DKA A;  2HKP A;  2QR1 A;  1YQK A;  1E42 A;  1VKL A;  3DPT A;  3CVS A;  2NVM A;  2Z8U A;  1EUV A;  2D0B A;  4TPS A;  1YTF A;  5JMV D;  5BMN A;  1M5Q 1;  2FUV A;  3IH7 A;  1MP9 A;  2QRE A;  1D3U A;  1C4G A;  2NOL A;  3RSM A;  1P5D X;  5JN5 A; 
#chains in the Genus database with same CATH homology
 4ROD B;  2IV8 A;  3F0Z A;  1QNA A;  2NOZ A;  1VTL E;  1QN3 A;  1KYU A;  3I0X A;  2O3O A;  1QN8 A;  3OCI A;  5IYC P;  2NOH A;  4PY5 A;  3N89 A;  3VN5 A;  1LWV A;  2NOB A;  1RM1 A;  1KY7 A;  4EJY A;  3ULX A;  1EBM A;  2NOF A;  4ROC B;  1TGH A;  2XHI A;  1W80 A;  1M3Q A;  2I5W A;  1QNC A;  2FGT A;  2HZS A;  1KYF A;  3I0W A;  3OST A;  3KTU A;  1NGM A;  1QN4 A;  2D0C A;  1QN6 A;  1B9K A;  1HU0 A;  1JFI C;  1YTB A;  2IV9 A;  3OC3 C;  3ASM A;  1N3C A;  1TBA B;  4ROE B;  1UT7 A;  1AIS A;  4DUL A;  1QN5 A;  2G30 A;  3KRM A;  2VJ0 A;  2LAE A;  1KO9 A;  4EJZ A;  1QNE A;  2MZ8 A;  3F10 A;  1VOK A;  1KY6 A;  4Q11 A;  1PCZ A;  1NVP A;  1FN7 A;  1QN9 A;  1QN7 A;  4I8O A;  1NH2 A;  1CDW A;  2HZM A;  3EIK A;  1QTS A;  1R4X A;  4WZS D;  3H1Z A;  3HS8 A;  5IYB P;  1UT4 A;  1LWY A;  1VOL B;  3HS9 A;  3SNS A;  1VTO A;  1KYD A;  1M3H A;  1YQR A;  1LWW A;  3DPU A;  1YQL A;  1N39 A;  1YQM A;  2NOI A;  5AN4 A;  1PZD A;  1N3A A;  3RPJ A;  2NOE A;  1C9B B;  3OSM A;  1QNB A;  1TBP A;  2MJ7 A;  5IYD P;  2YH5 A;  2JOI A;  4B0A A;  1QTP A;  2D0A A;  1YQK A;  1E42 A;  3DPT A;  2Z8U A;  2D0B A;  4TPS A;  1YTF A;  3IH7 A;  1MP9 A;  2NOL A;  1D3U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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