5IYDP

Human core-pic in the initial transcribing state (no iis)
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
185
structure length
185
Chain Sequence
TPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
molecule tags Transcription, transferase/dna/rna
source organism Homo sapiens
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 39
structure length 185
sequence length 185
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
P PF00352 TBP Transcription factor TFIID (or TATA-binding protein, TBP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 5iydP01
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 5iydP02
1C9BB 4ROCB 1R4XA 1PZDA 3HS8A 1TBAB 1VTLE 1TBPA 1KY7A 1RM1A 1QTSA 1CDWA 2D0CA 3HS9A 1KYFA 1KY6A 5IYCP 1QNAA 1QN7A 5IYBP 3EIKA 1QN9A 1E42A 1NVPA 1W80A 3ASMA 4RODB 4WZSD 1PCZA 2G30A 1QN5A 1QTPA 2D0BA 1QNEA 2IV9A 2D0AA 1YTBA 3OCIA 4B0AA 1VOLB 1QN6A 1AISA 2MJ7A 1B9KA 1QN3A 1MP9A 4PY5A 1VOKA 1QN4A 2IV8A 5IYDP 1YTFA 3H1ZA 1JFIC 1KYUA 2VJ0A 1NGMA 1QN8A 4ROEB 2Z8UA 3VN5A 1TGHA 1KYDA 1NH2A 1D3UA 3OC3C 1VTOA 1QNBA 1QNCA
chains in the Genus database with same CATH superfamily
4ROCB 4EAKA 1VTLE 5BMNA 2H4LX 1PCMX 2D0CA 3HS9A 1C4GA 1QN7A 1Q9UA 5IYBP 2Y8LA 5F9CA 1EBMA 1M3HA 2QRDA 2V92A 1PVSA 2Z0FA 1KFIA 3TDHA 3TE5A 1QTPA 5AN4A 3I3WA 4D7QA 1TUOA 3OLPA 1QNEA 3C04A 3CW7A 1K35A 1YQLA 1QN3A 1B9KA 3RSMA 1QN4A 2IV8A 1YTFA 2NOZA 3H1ZA 1JFIC 1NGMA 2NOIA 3VN5A 1TGHA 3DPTA 4HJHA 1VKLA 3CWTA 2QLVA 3RPJA 1QNBA 3CVSA 1LXTA 1JDYA 1C47A 1PZDA 3CWSA 2DKCA 1TBAB 1P5DX 1TBPA 1KY7A 3KTUA 1QTSA 3PMGA 4BJUA 1KY6A 3DPUA 4D7RA 1E42A 5JN5A 3BKQX 4WZSD 1PCZA 1EUVA 2NLVA 5EPCA 2D0BA 3ENCA 1N3AA 2D0AA 3OCIA 3ULXA 3OH6A 1FN7A 1N39A 3F0ZA 1YQKA 2DKDA 1QN6A 4WX8A 1MP9A 1T6AA 1KO9A 1UT4A 1VOKA 2EHBD 2OOYA 5IYDP 1QN8A 1WJWA 2VJ0A 4WXAA 1N3CA 4CFFA 3ENOC 4DULA 2NOBA 3OC3C 2HZSA 2YH5A 2JOIA 3I0WA 3UW2A 1C9BB 3F10A 2NOEA 2NWVA 2HZMA 5JMVD 2QRCA 3EAYA 4EAJA 1RM1A 5BMPA 1KYFA 5IYCP 2HKPA 2HL9A 1DIZA 4QG5A 3OGDA 3T4NA 1LWVA 1M5Q1 2QR1A 1QN9A 4EJZA 1W80A 2F7LA 3ASMA 1V5SA 4RODB 3I0XA 2FGTA 3OSEA 3D7QA 3IH7A 4C7PA 4MRQA 1KFQA 2ZFDB 2QREA 2NOFA 4B0AA 3NA5A 1AISA 2MJ7A 3SNSA 3CVTA 4PY5A 3CWAA 1KYUA 4ROEB 2JHJA 2Z8UA 2YA3A 2Y8QA 2XHIA 1KYDA 1D3UA 1VTOA 1QNCA 2MZ8A 1R4XA 3HS8A 3OSTA 2NVMA 3CWUA 1YQRA 2H5AX 1CDWA 4IL8A 1QNAA 1P5GX 1J3MA 2PWWA 3PDKA 2OOXA 2FKFA 3EIKA 1M3QA 2NOLA 1XSZA 4EAGA 1MPGA 1NVPA 4EJYA 2V9JA 2G30A 2HL8A 1LWWA 1QN5A 2R5XA 3OH9A 1HU0A 2JPIA 2IV9A 1YTBA 1PCJX 2JHNA 1VOLB 1WQAA 2FKMX 2O3OA 3OSMA 1LWYA 2LAEA 3KRMA 5HSHA 4I8OA 2FUVA 3N89A 5KL0A 3D4VA 1UL7A 1UT7A 2DKAA 4Q11A 4TPSA 4EAIA 4EALA 1K2YX 2V8QA 1YQMA 1NH2A 2NOHA 2I5WA
chains in the Genus database with same CATH topology
4ROCB 1VTLE 2D0CA 3HS9A 1QN7A 5IYBP 1EBMA 1M3HA 1QTPA 5AN4A 1QNEA 1YQLA 1QN3A 1B9KA 1QN4A 2IV8A 1YTFA 2NOZA 3H1ZA 1JFIC 1NGMA 2NOIA 3VN5A 1TGHA 3DPTA 3RPJA 1QNBA 1PZDA 1TBAB 1TBPA 1KY7A 3KTUA 1QTSA 1KY6A 3DPUA 1E42A 4WZSD 1PCZA 2D0BA 1N3AA 2D0AA 3OCIA 3ULXA 1FN7A 1N39A 3F0ZA 1YQKA 1QN6A 1MP9A 1VOKA 1KO9A 1UT4A 5IYDP 1QN8A 2VJ0A 4DULA 2NOBA 3OC3C 2HZSA 2YH5A 2JOIA 3I0WA 1C9BB 3F10A 2NOEA 2HZMA 1RM1A 1KYFA 5IYCP 1LWVA 1QN9A 4EJZA 1W80A 3ASMA 4RODB 3I0XA 2FGTA 3IH7A 2NOFA 4B0AA 1AISA 2MJ7A 3SNSA 4PY5A 1KYUA 4ROEB 2Z8UA 2XHIA 1KYDA 1D3UA 1VTOA 1QNCA 2MZ8A 1R4XA 3HS8A 3OSTA 1YQRA 1CDWA 1QNAA 1M3QA 3EIKA 2NOLA 1NVPA 4EJYA 2G30A 1LWWA 1QN5A 1HU0A 2IV9A 1YTBA 1VOLB 2O3OA 3OSMA 1LWYA 2LAEA 3KRMA 4I8OA 3N89A 1UT7A 4Q11A 1NH2A 1N3CA 4TPSA 1YQMA 2NOHA 2I5WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1C9B B;  4ROC B;  1R4X A;  1PZD A;  3HS8 A;  1TBA B;  1VTL E;  1TBP A;  1KY7 A;  1RM1 A;  1QTS A;  1CDW A;  2D0C A;  3HS9 A;  1KYF A;  1KY6 A;  5IYC P;  1QNA A;  1QN7 A;  5IYB P;  3EIK A;  1QN9 A;  1E42 A;  1NVP A;  1W80 A;  3ASM A;  4ROD B;  4WZS D;  1PCZ A;  2G30 A;  1QN5 A;  1QTP A;  2D0B A;  1QNE A;  2IV9 A;  2D0A A;  1YTB A;  3OCI A;  4B0A A;  1VOL B;  1QN6 A;  1AIS A;  2MJ7 A;  1B9K A;  1QN3 A;  1MP9 A;  4PY5 A;  1VOK A;  1QN4 A;  2IV8 A;  5IYD P;  1YTF A;  3H1Z A;  1JFI C;  1KYU A;  2VJ0 A;  1NGM A;  1QN8 A;  4ROE B;  2Z8U A;  3VN5 A;  1TGH A;  1KYD A;  1NH2 A;  1D3U A;  3OC3 C;  1VTO A;  1QNB A;  1QNC A; 
#chains in the Genus database with same CATH topology
 4ROC B;  4EAK A;  1VTL E;  5BMN A;  2H4L X;  1PCM X;  2D0C A;  3HS9 A;  1C4G A;  1QN7 A;  1Q9U A;  5IYB P;  2Y8L A;  5F9C A;  1EBM A;  1M3H A;  2QRD A;  2V92 A;  1PVS A;  2Z0F A;  1KFI A;  3TDH A;  3TE5 A;  1QTP A;  5AN4 A;  3I3W A;  4D7Q A;  1TUO A;  3OLP A;  1QNE A;  3C04 A;  3CW7 A;  1K35 A;  1YQL A;  1QN3 A;  1B9K A;  3RSM A;  1QN4 A;  2IV8 A;  1YTF A;  2NOZ A;  3H1Z A;  1JFI C;  1NGM A;  2NOI A;  3VN5 A;  1TGH A;  3DPT A;  4HJH A;  1VKL A;  3CWT A;  2QLV A;  3RPJ A;  1QNB A;  3CVS A;  1LXT A;  1JDY A;  1C47 A;  1PZD A;  3CWS A;  2DKC A;  1TBA B;  1P5D X;  1TBP A;  1KY7 A;  3KTU A;  1QTS A;  3PMG A;  4BJU A;  1KY6 A;  3DPU A;  4D7R A;  1E42 A;  5JN5 A;  3BKQ X;  4WZS D;  1PCZ A;  1EUV A;  2NLV A;  5EPC A;  2D0B A;  3ENC A;  1N3A A;  2D0A A;  3OCI A;  3ULX A;  3OH6 A;  1FN7 A;  1N39 A;  3F0Z A;  1YQK A;  2DKD A;  1QN6 A;  4WX8 A;  1MP9 A;  1T6A A;  1KO9 A;  1UT4 A;  1VOK A;  2EHB D;  2OOY A;  5IYD P;  1QN8 A;  1WJW A;  2VJ0 A;  4WXA A;  1N3C A;  4CFF A;  3ENO C;  4DUL A;  2NOB A;  3OC3 C;  2HZS A;  2YH5 A;  2JOI A;  3I0W A;  3UW2 A;  1C9B B;  3F10 A;  2NOE A;  2NWV A;  2HZM A;  5JMV D;  2QRC A;  3EAY A;  4EAJ A;  1RM1 A;  5BMP A;  1KYF A;  5IYC P;  2HKP A;  2HL9 A;  1DIZ A;  4QG5 A;  3OGD A;  3T4N A;  1LWV A;  1M5Q 1;  2QR1 A;  1QN9 A;  4EJZ A;  1W80 A;  2F7L A;  3ASM A;  1V5S A;  4ROD B;  3I0X A;  2FGT A;  3OSE A;  3D7Q A;  3IH7 A;  4C7P A;  4MRQ A;  1KFQ A;  2ZFD B;  2QRE A;  2NOF A;  4B0A A;  3NA5 A;  1AIS A;  2MJ7 A;  3SNS A;  3CVT A;  4PY5 A;  3CWA A;  1KYU A;  4ROE B;  2JHJ A;  2Z8U A;  2YA3 A;  2Y8Q A;  2XHI A;  1KYD A;  1D3U A;  1VTO A;  1QNC A;  2MZ8 A;  1R4X A;  3HS8 A;  3OST A;  2NVM A;  3CWU A;  1YQR A;  2H5A X;  1CDW A;  4IL8 A;  1QNA A;  1P5G X;  1J3M A;  2PWW A;  3PDK A;  2OOX A;  2FKF A;  3EIK A;  1M3Q A;  2NOL A;  1XSZ A;  4EAG A;  1MPG A;  1NVP A;  4EJY A;  2V9J A;  2G30 A;  2HL8 A;  1LWW A;  1QN5 A;  2R5X A;  3OH9 A;  1HU0 A;  2JPI A;  2IV9 A;  1YTB A;  1PCJ X;  2JHN A;  1VOL B;  1WQA A;  2FKM X;  2O3O A;  3OSM A;  1LWY A;  2LAE A;  3KRM A;  5HSH A;  4I8O A;  2FUV A;  3N89 A;  5KL0 A;  3D4V A;  1UL7 A;  1UT7 A;  2DKA A;  4Q11 A;  4TPS A;  4EAI A;  4EAL A;  1K2Y X;  2V8Q A;  1YQM A;  1NH2 A;  2NOH A;  2I5W A; 
#chains in the Genus database with same CATH homology
 4ROC B;  1VTL E;  2D0C A;  3HS9 A;  1QN7 A;  5IYB P;  1EBM A;  1M3H A;  1QTP A;  5AN4 A;  1QNE A;  1YQL A;  1QN3 A;  1B9K A;  1QN4 A;  2IV8 A;  1YTF A;  2NOZ A;  3H1Z A;  1JFI C;  1NGM A;  2NOI A;  3VN5 A;  1TGH A;  3DPT A;  3RPJ A;  1QNB A;  1PZD A;  1TBA B;  1TBP A;  1KY7 A;  3KTU A;  1QTS A;  1KY6 A;  3DPU A;  1E42 A;  4WZS D;  1PCZ A;  2D0B A;  1N3A A;  2D0A A;  3OCI A;  3ULX A;  1FN7 A;  1N39 A;  3F0Z A;  1YQK A;  1QN6 A;  1MP9 A;  1VOK A;  1KO9 A;  1UT4 A;  5IYD P;  1QN8 A;  2VJ0 A;  4DUL A;  2NOB A;  3OC3 C;  2HZS A;  2YH5 A;  2JOI A;  3I0W A;  1C9B B;  3F10 A;  2NOE A;  2HZM A;  1RM1 A;  1KYF A;  5IYC P;  1LWV A;  1QN9 A;  4EJZ A;  1W80 A;  3ASM A;  4ROD B;  3I0X A;  2FGT A;  3IH7 A;  2NOF A;  4B0A A;  1AIS A;  2MJ7 A;  3SNS A;  4PY5 A;  1KYU A;  4ROE B;  2Z8U A;  2XHI A;  1KYD A;  1D3U A;  1VTO A;  1QNC A;  2MZ8 A;  1R4X A;  3HS8 A;  3OST A;  1YQR A;  1CDW A;  1QNA A;  1M3Q A;  3EIK A;  2NOL A;  1NVP A;  4EJY A;  2G30 A;  1LWW A;  1QN5 A;  1HU0 A;  2IV9 A;  1YTB A;  1VOL B;  2O3O A;  3OSM A;  1LWY A;  2LAE A;  3KRM A;  4I8O A;  3N89 A;  1UT7 A;  4Q11 A;  1NH2 A;  1N3C A;  4TPS A;  1YQM A;  2NOH A;  2I5W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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