2HZSA

Structure of the mediator head submodule med8c/18/20
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
208
structure length
203
Chain Sequence
GKSAVIFVERATPATLTELKDALSNSILSVRDPWSIDFRTYRCSIKNLPADVSKLMYSITFHHHGRQTVLIKDNSAMVTTAAAADIPPALVFNGSSTGVPESIDTILSSKLSNIWMQRQLIKGDAGETLILDGLTVRLVNLFSSTGFKGLLIELQADEAGEFETKIAGIEGHLAEIRAKEYKTSSDSLNEICDLAYQYVRALE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
pubmed doi rcsb
molecule tags Transcription
source organism Saccharomyces cerevisiae
molecule keywords RNA polymerase II mediator complex subunit 20
total genus 48
structure length 203
sequence length 208
chains with identical sequence C, E, G
ec nomenclature
pdb deposition date 2006-08-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.140.20 Mainly Beta Single Sheet q64v53_bacfr protein fold q64v53_bacfr protein fold 2hzsA02
3.30.310.180 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 2hzsA01
2HZMA 2HZSA
chains in the Genus database with same CATH superfamily
2DKDA 2QRCA 1P5GX 2JPIA 2NOHA 1TBPA 1CDWA 2OOYA 3PMGA 1QN3A 4D7RA 2EOCA 1P5DX 3OSEA 3OSTA 2JOIA 4ROCB 1QNBA 1B9KA 3ASMA 1K2YX 3I3WA 1R4XA 3F10A 4B0AA 3CWAA 3CW7A 3T4NA 1EUVA 4OQBC 3NA5A 1PCMX 3DPTA 2MJ7A 3IH7A 3OH9A 3I0WA 3RPJA 3KRMA 3UW2A 3TE5A 4CFFA 5JMVD 3D7QA 5AN4A 1YQKA 1HU0A 1VKLA 4EAGA 2NOBA 1PCZA 2NLVA 3EAYA 1KYUA 4EALA 1D3UA 1LXTA 2I5WA 2NOFA 1YQRA 3H1ZA 4EAJA 1LWWA 3ENCA 3VN5A 3N89A 2YA3A 2JHNA 1YQLA 2JHJA 1QNEA 5BMNA 4DQYC 1E42A 2G30A 4WZSD 1VOLB 1YTBA 4EAKA 1M3QA 1QNAA 4D7QA 1M5Q1 1TUOA 2HKPA 2Z8UA 3EIKA 1TBAB 2O3OA 2F7LA 4C7PA 3C04A 1QN4A 1JDYA 1K35A 1DIZA 3F0ZA 1KFIA 3HS9A 1PZDA 5JN5A 1NH2A 2IV8A 1QN9A 2FKFA 4MRQA 5IYBP 1NGMA 2V92A 3SNSA 2HZSA 1MPGA 2V9JA 4BJUA 2FKMX 2NOLA 2YH5A 2LAEA 5BMPA 2R5XA 1KO9A 1JFIC 1QTPA 2CR9A 5HSHA 1KFQA 3DPUA 2FGTA 1AISA 1QN5A 5IYDP 3OH6A 1FN7A 1UT4A 4I8OA 1LWYA 2D0CA 3CWSA 1QN8A 5EPCA 1YQMA 4ROEB 3OSMA 1TGHA 3OLPA 3PDKA 4Q11A 2NOEA 1XSZA 2VJ0A 1KYFA 4RODB 2D0AA 1J3MA 1VTLE 2RA8A 4OPXC 3TDHA 2FUVA 3CVSA 1N39A 1V5SA 2Y8QA 3KTUA 1VTOA 1WJWA 2H5AX 2HL8A 3CWTA 5KL0A 2NOIA 3ULXA 1RM1A 1M3HA 3OGDA 1NVPA 3OC3C 2Z0FA 4OQAC 2NVMA 2PWWA 2DKCA 1UT7A 2HL9A 2IV9A 1PCJX 4DULA 2V8QA 2OOXA 1WQAA 1KY6A 1QTSA 3OCIA 1MP9A 1VOKA 4IL8A 4HJHA 1N3CA 2Y8LA 4QG5A 2DKAA 2EHBD 1YTFA 3CWUA 2H4LX 2QREA 3HS8A 5F9CA 2NOZA 2MZ8A 3RSMA 4EJYA 1EBMA 2QR1A 2HZMA 1KYDA 1KY7A 4EAIA 2XHIA 1LWVA 1PVSA 3BKQX 2D0BA 3D4VA 4PY5A 1W80A 4WXAA 3CVTA 2ZFDB 1UL7A 4TPSA 3I0XA 1QN7A 1QNCA 5IYCP 1N3AA 1T6AA 1Q9UA 1C4GA 3ENOC 4EJZA 1C9BB 2QRDA 2QLVA 4WX8A 1QN6A 2NWVA 1C47A
chains in the Genus database with same CATH topology
2NOHA 1TBPA 1CDWA 1QN3A 3OSTA 2JOIA 4ROCB 1QNBA 1B9KA 3ASMA 1R4XA 3F10A 4B0AA 3DPTA 2MJ7A 3IH7A 3I0WA 3RPJA 3KRMA 5AN4A 1YQKA 1HU0A 2NOBA 1PCZA 1D3UA 2NOFA 1KYUA 2I5WA 1YQRA 1LWWA 3VN5A 3N89A 1YQLA 1QNEA 1E42A 2G30A 4WZSD 1VOLB 1YTBA 1M3QA 1QNAA 3EIKA 2Z8UA 1TBAB 2O3OA 1QN4A 3F0ZA 3HS9A 1PZDA 1NH2A 2IV8A 1QN9A 5IYBP 1NGMA 3SNSA 2HZSA 2NOLA 2YH5A 2LAEA 1KO9A 1JFIC 1QTPA 3DPUA 2FGTA 1AISA 1QN5A 5IYDP 1FN7A 1UT4A 4I8OA 1LWYA 2D0CA 1QN8A 1YQMA 4ROEB 3OSMA 1TGHA 4Q11A 2NOEA 2VJ0A 4RODB 1KYFA 2D0AA 1VTLE 1N39A 3KTUA 1VTOA 2NOIA 3ULXA 1RM1A 1M3HA 1NVPA 3OC3C 1UT7A 2IV9A 4DULA 3OCIA 1KY6A 1QTSA 1MP9A 1VOKA 1N3CA 1YTFA 3HS8A 2NOZA 2MZ8A 4EJYA 1EBMA 2XHIA 1KYDA 2HZMA 1KY7A 1LWVA 2D0BA 4PY5A 1W80A 4TPSA 1QN7A 3I0XA 1QNCA 5IYCP 1N3AA 4EJZA 1C9BB 1QN6A 3H1ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HZM A;  2HZS A; 
#chains in the Genus database with same CATH topology
 2DKD A;  2QRC A;  1P5G X;  2JPI A;  2NOH A;  1TBP A;  1CDW A;  2OOY A;  3PMG A;  1QN3 A;  4D7R A;  2EOC A;  1P5D X;  3OSE A;  3OST A;  2JOI A;  4ROC B;  1QNB A;  1B9K A;  3ASM A;  1K2Y X;  3I3W A;  1R4X A;  3F10 A;  4B0A A;  3CWA A;  3CW7 A;  3T4N A;  1EUV A;  4OQB C;  3NA5 A;  1PCM X;  3DPT A;  2MJ7 A;  3IH7 A;  3OH9 A;  3I0W A;  3RPJ A;  3KRM A;  3UW2 A;  3TE5 A;  4CFF A;  5JMV D;  3D7Q A;  5AN4 A;  1YQK A;  1HU0 A;  1VKL A;  4EAG A;  2NOB A;  1PCZ A;  2NLV A;  3EAY A;  1KYU A;  4EAL A;  1D3U A;  1LXT A;  2I5W A;  2NOF A;  1YQR A;  3H1Z A;  4EAJ A;  1LWW A;  3ENC A;  3VN5 A;  3N89 A;  2YA3 A;  2JHN A;  1YQL A;  2JHJ A;  1QNE A;  5BMN A;  4DQY C;  1E42 A;  2G30 A;  4WZS D;  1VOL B;  1YTB A;  4EAK A;  1M3Q A;  1QNA A;  4D7Q A;  1M5Q 1;  1TUO A;  2HKP A;  2Z8U A;  3EIK A;  1TBA B;  2O3O A;  2F7L A;  4C7P A;  3C04 A;  1QN4 A;  1JDY A;  1K35 A;  1DIZ A;  3F0Z A;  1KFI A;  3HS9 A;  1PZD A;  5JN5 A;  1NH2 A;  2IV8 A;  1QN9 A;  2FKF A;  4MRQ A;  5IYB P;  1NGM A;  2V92 A;  3SNS A;  2HZS A;  1MPG A;  2V9J A;  4BJU A;  2FKM X;  2NOL A;  2YH5 A;  2LAE A;  5BMP A;  2R5X A;  1KO9 A;  1JFI C;  1QTP A;  2CR9 A;  5HSH A;  1KFQ A;  3DPU A;  2FGT A;  1AIS A;  1QN5 A;  5IYD P;  3OH6 A;  1FN7 A;  1UT4 A;  4I8O A;  1LWY A;  2D0C A;  3CWS A;  1QN8 A;  5EPC A;  1YQM A;  4ROE B;  3OSM A;  1TGH A;  3OLP A;  3PDK A;  4Q11 A;  2NOE A;  1XSZ A;  2VJ0 A;  1KYF A;  4ROD B;  2D0A A;  1J3M A;  1VTL E;  2RA8 A;  4OPX C;  3TDH A;  2FUV A;  3CVS A;  1N39 A;  1V5S A;  2Y8Q A;  3KTU A;  1VTO A;  1WJW A;  2H5A X;  2HL8 A;  3CWT A;  5KL0 A;  2NOI A;  3ULX A;  1RM1 A;  1M3H A;  3OGD A;  1NVP A;  3OC3 C;  2Z0F A;  4OQA C;  2NVM A;  2PWW A;  2DKC A;  1UT7 A;  2HL9 A;  2IV9 A;  1PCJ X;  4DUL A;  2V8Q A;  2OOX A;  1WQA A;  1KY6 A;  1QTS A;  3OCI A;  1MP9 A;  1VOK A;  4IL8 A;  4HJH A;  1N3C A;  2Y8L A;  4QG5 A;  2DKA A;  2EHB D;  1YTF A;  3CWU A;  2H4L X;  2QRE A;  3HS8 A;  5F9C A;  2NOZ A;  2MZ8 A;  3RSM A;  4EJY A;  1EBM A;  2QR1 A;  2HZM A;  1KYD A;  1KY7 A;  4EAI A;  2XHI A;  1LWV A;  1PVS A;  3BKQ X;  2D0B A;  3D4V A;  4PY5 A;  1W80 A;  4WXA A;  3CVT A;  2ZFD B;  1UL7 A;  4TPS A;  3I0X A;  1QN7 A;  1QNC A;  5IYC P;  1N3A A;  1T6A A;  1Q9U A;  1C4G A;  3ENO C;  4EJZ A;  1C9B B;  2QRD A;  2QLV A;  4WX8 A;  1QN6 A;  2NWV A;  1C47 A; 
#chains in the Genus database with same CATH homology
 2NOH A;  1TBP A;  1CDW A;  1QN3 A;  3OST A;  2JOI A;  4ROC B;  1QNB A;  1B9K A;  3ASM A;  1R4X A;  3F10 A;  4B0A A;  3DPT A;  2MJ7 A;  3IH7 A;  3I0W A;  3RPJ A;  3KRM A;  5AN4 A;  1YQK A;  1HU0 A;  2NOB A;  1PCZ A;  1D3U A;  2NOF A;  1KYU A;  2I5W A;  1YQR A;  1LWW A;  3VN5 A;  3N89 A;  1YQL A;  1QNE A;  1E42 A;  2G30 A;  4WZS D;  1VOL B;  1YTB A;  1M3Q A;  1QNA A;  3EIK A;  2Z8U A;  1TBA B;  2O3O A;  1QN4 A;  3F0Z A;  3HS9 A;  1PZD A;  1NH2 A;  2IV8 A;  1QN9 A;  5IYB P;  1NGM A;  3SNS A;  2HZS A;  2NOL A;  2YH5 A;  2LAE A;  1KO9 A;  1JFI C;  1QTP A;  3DPU A;  2FGT A;  1AIS A;  1QN5 A;  5IYD P;  1FN7 A;  1UT4 A;  4I8O A;  1LWY A;  2D0C A;  1QN8 A;  1YQM A;  4ROE B;  3OSM A;  1TGH A;  4Q11 A;  2NOE A;  2VJ0 A;  4ROD B;  1KYF A;  2D0A A;  1VTL E;  1N39 A;  3KTU A;  1VTO A;  2NOI A;  3ULX A;  1RM1 A;  1M3H A;  1NVP A;  3OC3 C;  1UT7 A;  2IV9 A;  4DUL A;  3OCI A;  1KY6 A;  1QTS A;  1MP9 A;  1VOK A;  1N3C A;  1YTF A;  3HS8 A;  2NOZ A;  2MZ8 A;  4EJY A;  1EBM A;  2XHI A;  1KYD A;  2HZM A;  1KY7 A;  1LWV A;  2D0B A;  4PY5 A;  1W80 A;  4TPS A;  1QN7 A;  3I0X A;  1QNC A;  5IYC P;  1N3A A;  4EJZ A;  1C9B B;  1QN6 A;  3H1Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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