2HZMA

Structure of the mediator head subcomplex med18/20
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
209
structure length
205
Chain Sequence
GKSAVIFVERATPATLTELKDALSNSILSVRDPWSIDFRTYRCSIKNLSKLMYSITFHHHGRQTVLIKDNSAMVTTAAAADIPPALVFNGSSTGVPESIDTILSSKLSNIWMQRQLIKGDAGETLILDGLTVRLVNLFSSTGFKGLLIELQADEAGEFETKIAGIEGHLAEIRAKEYKTSSDSLGPDTSNEICDLAYQYVRALEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
pubmed doi rcsb
molecule tags Transcription
source organism Saccharomyces cerevisiae
molecule keywords RNA polymerase II mediator complex subunit 20
total genus 51
structure length 205
sequence length 209
chains with identical sequence C, E, G
ec nomenclature
pdb deposition date 2006-08-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08612 Med20 TATA-binding related factor (TRF) of subunit 20 of Mediator complex
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.140.20 Mainly Beta Single Sheet q64v53_bacfr protein fold q64v53_bacfr protein fold 2hzmA02
3.30.310.180 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 2hzmA01
2HZSA 2HZMA
chains in the Genus database with same CATH superfamily
2D0AA 4OQAC 1VTOA 1N3CA 1QN9A 1QNAA 3ENCA 2FUVA 1QN7A 1E42A 1VTLE 4EALA 1LXTA 3F10A 5AN4A 4ROCB 1QTPA 1QNEA 1MP9A 1QN6A 2R5XA 3SNSA 2NOZA 1NH2A 5BMNA 2I5WA 5JN5A 1LWYA 4MRQA 5BMPA 3EIKA 3CWUA 1DIZA 5IYBP 4WX8A 1W80A 3I0WA 5EPCA 4BJUA 1MPGA 2QLVA 4B0AA 1QN8A 1PCMX 1KY6A 5F9CA 4OQBC 2NOIA 2NVMA 3KRMA 1M3QA 1K2YX 2HL9A 2QR1A 1J3MA 1HU0A 2V92A 1FN7A 3D7QA 3ASMA 3PMGA 3CVSA 2NOBA 3TE5A 3ENOC 2D0CA 2D0BA 1QNCA 1TGHA 4EAIA 3OH9A 1PZDA 2CR9A 1RM1A 3OSEA 3N89A 3D4VA 2VJ0A 3ULXA 3OCIA 2JPIA 1UL7A 1UT7A 2JHJA 3F0ZA 2QRCA 3VN5A 1JFIC 1QTSA 1N39A 4DQYC 2FKMX 1B9KA 3DPUA 1QN3A 4DULA 3RPJA 1PCJX 1TBPA 4D7RA 3OSTA 2OOXA 4I8OA 5IYDP 4IL8A 2FKFA 1K35A 2NWVA 2Y8LA 3CVTA 1YQMA 1KO9A 1YQLA 1KFQA 1KYUA 1P5DX 2F7LA 3CWSA 3CWTA 4EJYA 1Q9UA 3I0XA 3DPTA 1QNBA 1LWVA 2EOCA 1JDYA 4QG5A 4WZSD 4TPSA 2RA8A 1NGMA 3KTUA 1KYFA 1C4GA 1PVSA 3T4NA 4ROEB 2Z8UA 2YH5A 2IV9A 2NLVA 1P5GX 3PDKA 1TBAB 4Q11A 5KL0A 2NOFA 1WJWA 2NOHA 2ZFDB 1D3UA 2H5AX 2O3OA 4RODB 3HS9A 1N3AA 3NA5A 3OLPA 2DKAA 3OGDA 1C9BB 1AISA 1KY7A 2JHNA 2MZ8A 1WQAA 2V8QA 3CW7A 3I3WA 2QRDA 3RSMA 1YTBA 2YA3A 2HL8A 3C04A 1M3HA 1XSZA 1CDWA 4OPXC 4PY5A 2Y8QA 2H4LX 2IV8A 1NVPA 1V5SA 1YQRA 1T6AA 5JMVD 2HZSA 2LAEA 2FGTA 2MJ7A 3H1ZA 2V9JA 3BKQX 3EAYA 3OC3C 4C7PA 2HZMA 3IH7A 1PCZA 4WXAA 2PWWA 1TUOA 1VKLA 2DKDA 3CWAA 1YQKA 2HKPA 1UT4A 1EBMA 2QREA 1KYDA 5IYCP 4HJHA 2XHIA 2NOLA 2JOIA 4EJZA 1M5Q1 2OOYA 4D7QA 1LWWA 4EAGA 2G30A 2Z0FA 3HS8A 4EAKA 1KFIA 2DKCA 1QN4A 1EUVA 2NOEA 3UW2A 2EHBD 1VOKA 3OSMA 4CFFA 1QN5A 1C47A 4EAJA 5HSHA 1VOLB 3TDHA 1YTFA 3OH6A 1R4XA
chains in the Genus database with same CATH topology
2D0AA 1VTOA 1N3CA 1QN9A 1QNAA 1QN7A 1E42A 1VTLE 3F10A 5AN4A 4ROCB 1QTPA 1QNEA 1MP9A 1QN6A 3SNSA 2NOZA 1NH2A 2I5WA 1LWYA 3EIKA 5IYBP 1W80A 3I0WA 4B0AA 1QN8A 1KY6A 2NOIA 3KRMA 1M3QA 1HU0A 1FN7A 3ASMA 2NOBA 2D0CA 2D0BA 1QNCA 1TGHA 1PZDA 1RM1A 3N89A 2VJ0A 3ULXA 3OCIA 1UT7A 3F0ZA 3VN5A 1JFIC 1QTSA 1N39A 3DPUA 1QN3A 1B9KA 4DULA 3RPJA 1TBPA 3OSTA 4I8OA 5IYDP 1YQMA 1KO9A 1YQLA 1KYUA 4EJYA 3I0XA 3DPTA 1QNBA 1LWVA 4WZSD 4TPSA 1NGMA 3KTUA 1KYFA 4ROEB 2Z8UA 2YH5A 2IV9A 1TBAB 4Q11A 2NOFA 2NOHA 1D3UA 2O3OA 4RODB 3HS9A 1N3AA 1C9BB 1AISA 1KY7A 2MZ8A 1YTBA 1M3HA 1CDWA 4PY5A 2IV8A 1NVPA 1YQRA 2HZSA 2LAEA 2FGTA 2MJ7A 3H1ZA 3OC3C 2HZMA 3IH7A 1PCZA 1YQKA 1UT4A 1EBMA 1KYDA 5IYCP 2XHIA 2NOLA 2JOIA 4EJZA 1LWWA 2G30A 3HS8A 1QN4A 2NOEA 1VOKA 3OSMA 1QN5A 1VOLB 1YTFA 1R4XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HZS A;  2HZM A; 
#chains in the Genus database with same CATH topology
 2D0A A;  4OQA C;  1VTO A;  1N3C A;  1QN9 A;  1QNA A;  3ENC A;  2FUV A;  1QN7 A;  1E42 A;  1VTL E;  4EAL A;  1LXT A;  3F10 A;  5AN4 A;  4ROC B;  1QTP A;  1QNE A;  1MP9 A;  1QN6 A;  2R5X A;  3SNS A;  2NOZ A;  1NH2 A;  5BMN A;  2I5W A;  5JN5 A;  1LWY A;  4MRQ A;  5BMP A;  3EIK A;  3CWU A;  1DIZ A;  5IYB P;  4WX8 A;  1W80 A;  3I0W A;  5EPC A;  4BJU A;  1MPG A;  2QLV A;  4B0A A;  1QN8 A;  1PCM X;  1KY6 A;  5F9C A;  4OQB C;  2NOI A;  2NVM A;  3KRM A;  1M3Q A;  1K2Y X;  2HL9 A;  2QR1 A;  1J3M A;  1HU0 A;  2V92 A;  1FN7 A;  3D7Q A;  3ASM A;  3PMG A;  3CVS A;  2NOB A;  3TE5 A;  3ENO C;  2D0C A;  2D0B A;  1QNC A;  1TGH A;  4EAI A;  3OH9 A;  1PZD A;  2CR9 A;  1RM1 A;  3OSE A;  3N89 A;  3D4V A;  2VJ0 A;  3ULX A;  3OCI A;  2JPI A;  1UL7 A;  1UT7 A;  2JHJ A;  3F0Z A;  2QRC A;  3VN5 A;  1JFI C;  1QTS A;  1N39 A;  4DQY C;  2FKM X;  1B9K A;  3DPU A;  1QN3 A;  4DUL A;  3RPJ A;  1PCJ X;  1TBP A;  4D7R A;  3OST A;  2OOX A;  4I8O A;  5IYD P;  4IL8 A;  2FKF A;  1K35 A;  2NWV A;  2Y8L A;  3CVT A;  1YQM A;  1KO9 A;  1YQL A;  1KFQ A;  1KYU A;  1P5D X;  2F7L A;  3CWS A;  3CWT A;  4EJY A;  1Q9U A;  3I0X A;  3DPT A;  1QNB A;  1LWV A;  2EOC A;  1JDY A;  4QG5 A;  4WZS D;  4TPS A;  2RA8 A;  1NGM A;  3KTU A;  1KYF A;  1C4G A;  1PVS A;  3T4N A;  4ROE B;  2Z8U A;  2YH5 A;  2IV9 A;  2NLV A;  1P5G X;  3PDK A;  1TBA B;  4Q11 A;  5KL0 A;  2NOF A;  1WJW A;  2NOH A;  2ZFD B;  1D3U A;  2H5A X;  2O3O A;  4ROD B;  3HS9 A;  1N3A A;  3NA5 A;  3OLP A;  2DKA A;  3OGD A;  1C9B B;  1AIS A;  1KY7 A;  2JHN A;  2MZ8 A;  1WQA A;  2V8Q A;  3CW7 A;  3I3W A;  2QRD A;  3RSM A;  1YTB A;  2YA3 A;  2HL8 A;  3C04 A;  1M3H A;  1XSZ A;  1CDW A;  4OPX C;  4PY5 A;  2Y8Q A;  2H4L X;  2IV8 A;  1NVP A;  1V5S A;  1YQR A;  1T6A A;  5JMV D;  2HZS A;  2LAE A;  2FGT A;  2MJ7 A;  3H1Z A;  2V9J A;  3BKQ X;  3EAY A;  3OC3 C;  4C7P A;  2HZM A;  3IH7 A;  1PCZ A;  4WXA A;  2PWW A;  1TUO A;  1VKL A;  2DKD A;  3CWA A;  1YQK A;  2HKP A;  1UT4 A;  1EBM A;  2QRE A;  1KYD A;  5IYC P;  4HJH A;  2XHI A;  2NOL A;  2JOI A;  4EJZ A;  1M5Q 1;  2OOY A;  4D7Q A;  1LWW A;  4EAG A;  2G30 A;  2Z0F A;  3HS8 A;  4EAK A;  1KFI A;  2DKC A;  1QN4 A;  1EUV A;  2NOE A;  3UW2 A;  2EHB D;  1VOK A;  3OSM A;  4CFF A;  1QN5 A;  1C47 A;  4EAJ A;  5HSH A;  1VOL B;  3TDH A;  1YTF A;  3OH6 A;  1R4X A; 
#chains in the Genus database with same CATH homology
 2D0A A;  1VTO A;  1N3C A;  1QN9 A;  1QNA A;  1QN7 A;  1E42 A;  1VTL E;  3F10 A;  5AN4 A;  4ROC B;  1QTP A;  1QNE A;  1MP9 A;  1QN6 A;  3SNS A;  2NOZ A;  1NH2 A;  2I5W A;  1LWY A;  3EIK A;  5IYB P;  1W80 A;  3I0W A;  4B0A A;  1QN8 A;  1KY6 A;  2NOI A;  3KRM A;  1M3Q A;  1HU0 A;  1FN7 A;  3ASM A;  2NOB A;  2D0C A;  2D0B A;  1QNC A;  1TGH A;  1PZD A;  1RM1 A;  3N89 A;  2VJ0 A;  3ULX A;  3OCI A;  1UT7 A;  3F0Z A;  3VN5 A;  1JFI C;  1QTS A;  1N39 A;  3DPU A;  1QN3 A;  1B9K A;  4DUL A;  3RPJ A;  1TBP A;  3OST A;  4I8O A;  5IYD P;  1YQM A;  1KO9 A;  1YQL A;  1KYU A;  4EJY A;  3I0X A;  3DPT A;  1QNB A;  1LWV A;  4WZS D;  4TPS A;  1NGM A;  3KTU A;  1KYF A;  4ROE B;  2Z8U A;  2YH5 A;  2IV9 A;  1TBA B;  4Q11 A;  2NOF A;  2NOH A;  1D3U A;  2O3O A;  4ROD B;  3HS9 A;  1N3A A;  1C9B B;  1AIS A;  1KY7 A;  2MZ8 A;  1YTB A;  1M3H A;  1CDW A;  4PY5 A;  2IV8 A;  1NVP A;  1YQR A;  2HZS A;  2LAE A;  2FGT A;  2MJ7 A;  3H1Z A;  3OC3 C;  2HZM A;  3IH7 A;  1PCZ A;  1YQK A;  1UT4 A;  1EBM A;  1KYD A;  5IYC P;  2XHI A;  2NOL A;  2JOI A;  4EJZ A;  1LWW A;  2G30 A;  3HS8 A;  1QN4 A;  2NOE A;  1VOK A;  3OSM A;  1QN5 A;  1VOL B;  1YTF A;  1R4X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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