2HZSA

Structure of the mediator head submodule med8c/18/20
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
208
structure length
203
Chain Sequence
GKSAVIFVERATPATLTELKDALSNSILSVRDPWSIDFRTYRCSIKNLPADVSKLMYSITFHHHGRQTVLIKDNSAMVTTAAAADIPPALVFNGSSTGVPESIDTILSSKLSNIWMQRQLIKGDAGETLILDGLTVRLVNLFSSTGFKGLLIELQADEAGEFETKIAGIEGHLAEIRAKEYKTSSDSLNEICDLAYQYVRALE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
pubmed doi rcsb
molecule tags Transcription
source organism Saccharomyces cerevisiae
molecule keywords RNA polymerase II mediator complex subunit 20
total genus 48
structure length 203
sequence length 208
chains with identical sequence C, E, G
ec nomenclature
pdb deposition date 2006-08-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.140.20 Mainly Beta Single Sheet q64v53_bacfr protein fold q64v53_bacfr protein fold 2hzsA02
3.30.310.180 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 2hzsA01
2HZMA 2HZSA
chains in the Genus database with same CATH superfamily
1AISA 1PZDA 2IV9A 1M3QA 2QLVA 2FGTA 4MRQA 4HJHA 2NOFA 3TDHA 1C9BB 5BMNA 2ZFDB 1VKLA 3CWTA 1P5GX 2D0AA 1YQKA 1NGMA 1P5DX 2DKCA 3I0WA 1FN7A 2O3OA 3OGDA 1KYDA 3D7QA 3OSTA 3HS9A 1QN8A 5AN4A 4ROCB 4PY5A 3I3WA 2Y8QA 3IH7A 3OCIA 1UT7A 3VN5A 1YTFA 2NOZA 2JHJA 2F7LA 1MPGA 1C4GA 1E42A 1NVPA 1N39A 1KYUA 1YQLA 1KFQA 1PCJX 1EUVA 2VJ0A 5KL0A 1QTPA 2HKPA 2PWWA 5IYBP 3CWAA 3KRMA 1N3AA 2NOHA 1WQAA 5JN5A 2JPIA 2XHIA 4EJZA 2HZMA 4DQYC 1XSZA 2H5AX 2NOLA 1Q9UA 2FUVA 2Z8UA 3EAYA 4TPSA 2OOXA 1K35A 1QTSA 1LWVA 5JMVD 2HL8A 2MZ8A 2D0CA 3N89A 4IL8A 3SNSA 1WJWA 2G30A 4WZSD 3UW2A 1K2YX 2V9JA 4D7RA 1YTBA 1UL7A 2R5XA 3HS8A 1LWYA 2HL9A 4CFFA 4OQBC 1T6AA 1NH2A 3H1ZA 1C47A 2EHBD 2EOCA 5EPCA 4EAIA 4RODB 3ENOC 3BKQX 3KTUA 4EAGA 1M5Q1 3EIKA 3OLPA 3ULXA 2LAEA 2Y8LA 3CWUA 1VOKA 4QG5A 3ENCA 4DULA 1QN6A 2FKMX 3RPJA 1PCMX 3PMGA 2QREA 2HZSA 3C04A 4EJYA 1DIZA 4ROEB 3CVTA 3RSMA 1QNEA 2NWVA 5IYDP 3CVSA 1YQMA 1QNBA 1TBAB 4EALA 1QNCA 3CWSA 1CDWA 3DPUA 4Q11A 2D0BA 2QR1A 4BJUA 2I5WA 2H4LX 2Z0FA 2NOBA 1B9KA 2QRCA 3F0ZA 3F10A 1TGHA 4I8OA 1KY6A 2OOYA 1QNAA 2JOIA 2NOEA 1M3HA 1LWWA 1EBMA 2V8QA 1KO9A 1QN5A 2RA8A 2NOIA 1TBPA 3TE5A 1QN7A 1N3CA 1HU0A 2YA3A 2CR9A 2DKDA 2NVMA 2IV8A 3I0XA 4B0AA 1RM1A 1QN4A 1W80A 2V92A 1MP9A 1PVSA 3ASMA 3OSMA 4OQAC 1UT4A 2JHNA 1VOLB 4EAJA 1TUOA 4WX8A 4D7QA 2NLVA 3PDKA 1J3MA 1KFIA 2FKFA 1VTLE 1V5SA 4OPXC 2YH5A 4WXAA 3DPTA 5F9CA 3OH9A 3CW7A 1QN9A 3NA5A 3T4NA 4C7PA 1KY7A 1LXTA 3OSEA 1PCZA 5IYCP 2QRDA 3OC3C 1QN3A 2DKAA 1VTOA 5HSHA 1JFIC 2MJ7A 3OH6A 3D4VA 1R4XA 1YQRA 5BMPA 1D3UA 1KYFA 4EAKA 1JDYA
chains in the Genus database with same CATH topology
1AISA 1PZDA 2IV9A 1M3QA 2FGTA 2NOFA 1C9BB 2D0AA 1YQKA 1NGMA 3I0WA 1FN7A 2O3OA 1KYDA 3OSTA 1QN8A 3HS9A 4PY5A 5AN4A 4ROCB 3IH7A 1YTFA 3OCIA 1UT7A 3VN5A 2NOZA 1E42A 1NVPA 1N39A 1KYUA 1YQLA 2VJ0A 5IYBP 1QTPA 1N3AA 3KRMA 2NOHA 2XHIA 4EJZA 2HZMA 2NOLA 4TPSA 2Z8UA 1QTSA 1LWVA 2MZ8A 2D0CA 3N89A 3SNSA 2G30A 4WZSD 1YTBA 3HS8A 1LWYA 1NH2A 3H1ZA 4RODB 3KTUA 3EIKA 3ULXA 2LAEA 1VOKA 4DULA 1QN6A 3RPJA 2HZSA 4EJYA 4ROEB 1QNEA 5IYDP 1YQMA 1QNBA 1TBAB 1QNCA 1CDWA 3DPUA 4Q11A 2D0BA 2I5WA 2NOBA 1B9KA 3F0ZA 3F10A 1TGHA 4I8OA 1KY6A 1QNAA 2JOIA 2NOEA 1M3HA 1LWWA 1EBMA 1QN5A 1KO9A 2NOIA 1TBPA 1QN7A 1N3CA 1HU0A 2IV8A 3I0XA 4B0AA 1RM1A 1QN4A 1W80A 1MP9A 3ASMA 3OSMA 1UT4A 1VOLB 1VTLE 2YH5A 3DPTA 1QN9A 1KY7A 1PCZA 5IYCP 3OC3C 1QN3A 1VTOA 1JFIC 2MJ7A 1D3UA 1R4XA 1YQRA 1KYFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HZM A;  2HZS A; 
#chains in the Genus database with same CATH topology
 1AIS A;  1PZD A;  2IV9 A;  1M3Q A;  2QLV A;  2FGT A;  4MRQ A;  4HJH A;  2NOF A;  3TDH A;  1C9B B;  5BMN A;  2ZFD B;  1VKL A;  3CWT A;  1P5G X;  2D0A A;  1YQK A;  1NGM A;  1P5D X;  2DKC A;  3I0W A;  1FN7 A;  2O3O A;  3OGD A;  1KYD A;  3D7Q A;  3OST A;  3HS9 A;  1QN8 A;  5AN4 A;  4ROC B;  4PY5 A;  3I3W A;  2Y8Q A;  3IH7 A;  3OCI A;  1UT7 A;  3VN5 A;  1YTF A;  2NOZ A;  2JHJ A;  2F7L A;  1MPG A;  1C4G A;  1E42 A;  1NVP A;  1N39 A;  1KYU A;  1YQL A;  1KFQ A;  1PCJ X;  1EUV A;  2VJ0 A;  5KL0 A;  1QTP A;  2HKP A;  2PWW A;  5IYB P;  3CWA A;  3KRM A;  1N3A A;  2NOH A;  1WQA A;  5JN5 A;  2JPI A;  2XHI A;  4EJZ A;  2HZM A;  4DQY C;  1XSZ A;  2H5A X;  2NOL A;  1Q9U A;  2FUV A;  2Z8U A;  3EAY A;  4TPS A;  2OOX A;  1K35 A;  1QTS A;  1LWV A;  5JMV D;  2HL8 A;  2MZ8 A;  2D0C A;  3N89 A;  4IL8 A;  3SNS A;  1WJW A;  2G30 A;  4WZS D;  3UW2 A;  1K2Y X;  2V9J A;  4D7R A;  1YTB A;  1UL7 A;  2R5X A;  3HS8 A;  1LWY A;  2HL9 A;  4CFF A;  4OQB C;  1T6A A;  1NH2 A;  3H1Z A;  1C47 A;  2EHB D;  2EOC A;  5EPC A;  4EAI A;  4ROD B;  3ENO C;  3BKQ X;  3KTU A;  4EAG A;  1M5Q 1;  3EIK A;  3OLP A;  3ULX A;  2LAE A;  2Y8L A;  3CWU A;  1VOK A;  4QG5 A;  3ENC A;  4DUL A;  1QN6 A;  2FKM X;  3RPJ A;  1PCM X;  3PMG A;  2QRE A;  2HZS A;  3C04 A;  4EJY A;  1DIZ A;  4ROE B;  3CVT A;  3RSM A;  1QNE A;  2NWV A;  5IYD P;  3CVS A;  1YQM A;  1QNB A;  1TBA B;  4EAL A;  1QNC A;  3CWS A;  1CDW A;  3DPU A;  4Q11 A;  2D0B A;  2QR1 A;  4BJU A;  2I5W A;  2H4L X;  2Z0F A;  2NOB A;  1B9K A;  2QRC A;  3F0Z A;  3F10 A;  1TGH A;  4I8O A;  1KY6 A;  2OOY A;  1QNA A;  2JOI A;  2NOE A;  1M3H A;  1LWW A;  1EBM A;  2V8Q A;  1KO9 A;  1QN5 A;  2RA8 A;  2NOI A;  1TBP A;  3TE5 A;  1QN7 A;  1N3C A;  1HU0 A;  2YA3 A;  2CR9 A;  2DKD A;  2NVM A;  2IV8 A;  3I0X A;  4B0A A;  1RM1 A;  1QN4 A;  1W80 A;  2V92 A;  1MP9 A;  1PVS A;  3ASM A;  3OSM A;  4OQA C;  1UT4 A;  2JHN A;  1VOL B;  4EAJ A;  1TUO A;  4WX8 A;  4D7Q A;  2NLV A;  3PDK A;  1J3M A;  1KFI A;  2FKF A;  1VTL E;  1V5S A;  4OPX C;  2YH5 A;  4WXA A;  3DPT A;  5F9C A;  3OH9 A;  3CW7 A;  1QN9 A;  3NA5 A;  3T4N A;  4C7P A;  1KY7 A;  1LXT A;  3OSE A;  1PCZ A;  5IYC P;  2QRD A;  3OC3 C;  1QN3 A;  2DKA A;  1VTO A;  5HSH A;  1JFI C;  2MJ7 A;  3OH6 A;  3D4V A;  1R4X A;  1YQR A;  5BMP A;  1D3U A;  1KYF A;  4EAK A;  1JDY A; 
#chains in the Genus database with same CATH homology
 1AIS A;  1PZD A;  2IV9 A;  1M3Q A;  2FGT A;  2NOF A;  1C9B B;  2D0A A;  1YQK A;  1NGM A;  3I0W A;  1FN7 A;  2O3O A;  1KYD A;  3OST A;  1QN8 A;  3HS9 A;  4PY5 A;  5AN4 A;  4ROC B;  3IH7 A;  1YTF A;  3OCI A;  1UT7 A;  3VN5 A;  2NOZ A;  1E42 A;  1NVP A;  1N39 A;  1KYU A;  1YQL A;  2VJ0 A;  5IYB P;  1QTP A;  1N3A A;  3KRM A;  2NOH A;  2XHI A;  4EJZ A;  2HZM A;  2NOL A;  4TPS A;  2Z8U A;  1QTS A;  1LWV A;  2MZ8 A;  2D0C A;  3N89 A;  3SNS A;  2G30 A;  4WZS D;  1YTB A;  3HS8 A;  1LWY A;  1NH2 A;  3H1Z A;  4ROD B;  3KTU A;  3EIK A;  3ULX A;  2LAE A;  1VOK A;  4DUL A;  1QN6 A;  3RPJ A;  2HZS A;  4EJY A;  4ROE B;  1QNE A;  5IYD P;  1YQM A;  1QNB A;  1TBA B;  1QNC A;  1CDW A;  3DPU A;  4Q11 A;  2D0B A;  2I5W A;  2NOB A;  1B9K A;  3F0Z A;  3F10 A;  1TGH A;  4I8O A;  1KY6 A;  1QNA A;  2JOI A;  2NOE A;  1M3H A;  1LWW A;  1EBM A;  1QN5 A;  1KO9 A;  2NOI A;  1TBP A;  1QN7 A;  1N3C A;  1HU0 A;  2IV8 A;  3I0X A;  4B0A A;  1RM1 A;  1QN4 A;  1W80 A;  1MP9 A;  3ASM A;  3OSM A;  1UT4 A;  1VOL B;  1VTL E;  2YH5 A;  3DPT A;  1QN9 A;  1KY7 A;  1PCZ A;  5IYC P;  3OC3 C;  1QN3 A;  1VTO A;  1JFI C;  2MJ7 A;  1D3U A;  1R4X A;  1YQR A;  1KYF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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