3DPOA

Crystal structure of the substrate binding domain of e. coli dnak in complex with a short pyrrhocoricin-derived inhibitor peptide
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
213
structure length
213
Chain Sequence
VLLLDVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLMEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Allosteric coupling between the lid and interdomain linker in DnaK revealed by inhibitor binding studies
pubmed doi rcsb
molecule tags Chaperone, peptide binding protein
source organism Escherichia coli
molecule keywords Chaperone protein dnaK
total genus 62
structure length 213
sequence length 213
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-07-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.10 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Substrate Binding Domain Of Dnak; Chain:A; Domain 2 3dpoA02
2.60.34.10 Mainly Beta Sandwich Substrate Binding Domain Of DNAk; Chain A, domain 1 Substrate Binding Domain Of DNAk; Chain A, domain 1 3dpoA01
4EZZA 3DPOA 1CKRA 4F01A 4JNEA 5TKYA 1U00A 4JWEA 3DPQA 4E81A 4WV7A 3T49A 3L3OM 2QFFA 3DPPA 2KHOA 4EZTA 3DQGA 2OP6A 4JWCA 4FL9A 7HSCA 4EZRA 1DKYA 4JN4A 4R5LA 4R5GA 5E84A 3T4AG 3T48A 1DKZA 4EZSA 4EZPA 4R5JA 2WINM 4H6IA 4EZXA 1Q5LA 3DOBA 3OHXM 4HY9A 1DG4A 4JWIA 3QNJA 3C7NB 2BPRA 4H6HA 4EZQA 3D2EA 3H0XA 1DKXA 3D2FA 2QXLA 4EZNA 4EZOA 4JWDA 4PO2A 2V7YA 4R5IA 4WV5A 3T47A 4EZWA 4F00A 3N8EA 1YUWA 4HYBA 3T46A 4EZUA 1BPRA 4R5KA 4JNFA 4EZYA 3C7NA 4EZVA 4B9QA
chains in the Genus database with same CATH superfamily
2GAFD 4HR1B 5FLEX 2Q12A 4AZIA 3I04A 4BNEA 3C7NB 2EX3B 3Q0KA 4WV5A 4ATMA 2ELBA 3B51X 3EJRA 2PMRA 4G6QA 4WPCA 2F18A 4F01A 4JWEA 1MJGA 3O3OB 3ER9B 4HY9A 4JWIA 4AZGA 4JLCA 1JQKA 4DYLA 4R5IA 1TQVA 1YWMA 3SOGA 1QWUA 3BVTA 3T46A 3BUPA 3RPMA 4I1QA 2LM0A 3CZSA 3DPOA 2X5CA 5TKYA 2EWFA 4AZCA 2MI7A 4JN4A 1I4LA 2ALWA 2F1AA 1OA0A 3H0XA 3KAVA 1O7DB 4FM3A 4DCNC 4IWPA 3BUQA 4UDYX 4AZBA 4IWQA 4EZZA 3D51A 2RAIA 1U00A 4E81A 3ERCC 3G9GA 3UITA 1HTYA 4KIKB 3DQGA 3DOBA 4H8SA 3DX0A 3BVXA 1TQUA 2GA9D 2OZNB 4IW0A 2O0I1 4JWDA 2YIVX 4FZSA 3D4ZA 3CV5A 1QX1A 3DPQA 2F7QA 3KAWA 3O3NB 3ACOA 3I01A 3DPPA 3EJQA 2X3WA 7HSCA 5E84A 2FYVA 1R5EA 1UPXA 2V0OA 3RV0A 2BPRA 3DDFA 1SU8A 2X3VA 1SU6A 4I43A 2YIBA 1YUWA 4WV7A 3T49A 3DX1A 2N3KA 1URUA 2RAJA 2JNKA 2Z0NA 4UDXX 3PLTA 4AZCB 2YL6A 3BVWA 3HAIA 1CKRA 2OBMA 4FZPA 2WYHA 3BUDA 3SYVA 1X03A 2QFFA 4JWCA 3DX3A 3ER8C 4H6IA 1TQSA 2C08A 2OW7A 4MQDA 3ABHA 2V7YA 2YLLA 4B9QA 4IM2A 3VEAA 3L3OM 3EJPA 1R33A 4EZPA 4EZXA 3CZNA 1QWNA 4AZ6A 3D4YA 4H6HA 3D2EA 2D4CA 4E3CA 1BPRA 3C7NA 5C5BB 2X3XA 3FD9A 2OP6A 3B52X 1Q5LA 1O7DC 2NCZA 2LXYA 3BUBA 3DYTA 1W9MA 1OAOA 1I49A 2D1LA 3I39X 4AZHA 4PO2A 2Q13A 2RAKA 4M0MA 3D50A 3BLBA 1TQWA 2QKWA 3B53X 2JNSA 3BVUA 3KDRA 2YKTA 2QXLA 4EZWA 1ZWWA 4F00A 1Y2OA 4NQIA 4NSWA 4HYBA 2OO2A 4JNFA 3BUIA 4WPEA 1E1DA 3Q84A 4EZSA 1SUFA 3OHXM 3BVVA 3DX2A 3DDGA 4EZOA 2YL8A 4AKVA 3L3PA 4EZYA 3VKHA 3OK8A 3RV1A 3VEBA 1GNTA 4EZTA 2ZXQA 4ILHB 3T48A 1DKZA 2EFLA 4IM0A 3GI7A 4AZ7A 4EZQA 3HAHA 3D2FA 2OW6A 1GN9A 4IWOA 3O3MB 4FZOA 3QA8A 2YIAA 2F1BA 2OBLA 2ND0A 3D52A 3DX4A 3HAJA 2F7PA 3EJTA 3LLLA 4FL9A 1DKYA 4R5GA 3EJSA 3T4AG 4R5JA 3CVRA 4HR1A 2YL9A 1SU7A 1GNLA 3T47A 4EZUA 4R5KA 1OA1A 3LVTA 3CKDA 2KHOA 2YI8A 4EZRA 1E2UA 3CAZA 3LMFA 2WYIA 3QNJA 3OWGA 5KBPA 1HWWA 2YI9A 3M3WA 4D8JA 2Z8YA 4AZ5A 3QNIA 3F7WA 3QE6A 4AVMA 1HXKA 4NPHA 3QWEA 2PY6A 2RT6A 1WDZA 1X04A 2WINM 5FIGA 3EJUA 1I4DA 1ZYLA 1DKXA 4EZNA 2Z0VA 4IM3A 2F7OA 2FICA 3ZEFA 2EFKA 2Z0OA 2YLAA 1TQTA 3SBSA 4JNEA 2ND1A 3ZEDA 2GF4A 2YL5A 4R5LA 1DG4A 5C5BA 3A98A 2F7RA 3I2WA 1PS3A 1I4TA 4ILIA 1E9VA 4ILGA 1LQ7A 4JL9A 1R34A 4KIKA 3N8EA 3SBTB 4EZVA
chains in the Genus database with same CATH topology
2GAFD 2OBLA 3FD9A 2ND0A 4HR1B 5FLEX 3DPQA 3KAWA 3O3NB 3I01A 3DPPA 2OP6A 4FL9A 7HSCA 1DKYA 4R5GA 5E84A 3T4AG 1UPXA 3RV0A 4R5JA 3B52X 3I04A 1Q5LA 2NCZA 3C7NB 2BPRA 4HR1A 2EX3B 1SU8A 1W9MA 4WV5A 1OAOA 4PO2A 3I39X 1SU7A 1GNLA 3T47A 1SU6A 4EZUA 3B51X 2YIBA 1OA1A 4R5KA 1YUWA 4I43A 4G6QA 4M0MA 4F01A 4JWEA 4WV7A 3T49A 1MJGA 3O3OB 2KHOA 2YI8A 4EZRA 1E2UA 2N3KA 3B53X 3ER9B 3LMFA 2JNSA 4HY9A 4JWIA 3QNJA 3OWGA 4UDXX 4JLCA 3KDRA 1JQKA 2QXLA 2YI9A 4R5IA 4EZWA 4F00A 4D8JA 2Z8YA 4HYBA 3T46A 3F7WA 4JNFA 2LM0A 3DPOA 1CKRA 2X5CA 5TKYA 2OBMA 4NPHA 2EWFA 2PY6A 2QFFA 1E1DA 2RT6A 4JWCA 4JN4A 4EZSA 2WINM 1SUFA 4H6IA 3ER8C 5FIGA 3OHXM 4MQDA 1ZYLA 3H0XA 1OA0A 1DKXA 3KAVA 4FM3A 4EZNA 4EZOA 2V7YA 4IWPA 4UDYX 4IM3A 4EZYA 3VKHA 4IWQA 4B9QA 3ZEFA 4EZZA 3RV1A 3SBSA 4JNEA 1U00A 4E81A 1GNTA 4IM2A 3VEBA 3ERCC 3VEAA 3L3OM 2ND1A 3UITA 4EZTA 3ZEDA 4ILHB 4KIKB 4R5LA 3T48A 3DQGA 1DKZA 4IM0A 4EZPA 4EZXA 3DOBA 3GI7A 1DG4A 3A98A 2GA9D 4H6HA 4EZQA 4ILIA 3D2EA 1E9VA 4ILGA 3D2FA 4IW0A 4JWDA 2YIVX 4JL9A 1GN9A 4KIKA 4E3CA 3N8EA 4IWOA 3O3MB 3QA8A 1BPRA 3SBTB 3C7NA 4EZVA 2YIAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EZZ A;  3DPO A;  1CKR A;  4F01 A;  4JNE A;  5TKY A;  1U00 A;  4JWE A;  3DPQ A;  4E81 A;  4WV7 A;  3T49 A;  3L3O M;  2QFF A;  3DPP A;  2KHO A;  4EZT A;  3DQG A;  2OP6 A;  4JWC A;  4FL9 A;  7HSC A;  4EZR A;  1DKY A;  4JN4 A;  4R5L A;  4R5G A;  5E84 A;  3T4A G;  3T48 A;  1DKZ A;  4EZS A;  4EZP A;  4R5J A;  2WIN M;  4H6I A;  4EZX A;  1Q5L A;  3DOB A;  3OHX M;  4HY9 A;  1DG4 A;  4JWI A;  3QNJ A;  3C7N B;  2BPR A;  4H6H A;  4EZQ A;  3D2E A;  3H0X A;  1DKX A;  3D2F A;  2QXL A;  4EZN A;  4EZO A;  4JWD A;  4PO2 A;  2V7Y A;  4R5I A;  4WV5 A;  3T47 A;  4EZW A;  4F00 A;  3N8E A;  1YUW A;  4HYB A;  3T46 A;  4EZU A;  1BPR A;  4R5K A;  4JNF A;  4EZY A;  3C7N A;  4EZV A;  4B9Q A; 
#chains in the Genus database with same CATH topology
 2GAF D;  4HR1 B;  5FLE X;  2Q12 A;  4AZI A;  3I04 A;  4BNE A;  3C7N B;  2EX3 B;  3Q0K A;  4WV5 A;  4ATM A;  2ELB A;  3B51 X;  3EJR A;  2PMR A;  4G6Q A;  4WPC A;  2F18 A;  4F01 A;  4JWE A;  1MJG A;  3O3O B;  3ER9 B;  4HY9 A;  4JWI A;  4AZG A;  4JLC A;  1JQK A;  4DYL A;  4R5I A;  1TQV A;  1YWM A;  3SOG A;  1QWU A;  3BVT A;  3T46 A;  3BUP A;  3RPM A;  4I1Q A;  2LM0 A;  3CZS A;  3DPO A;  2X5C A;  5TKY A;  2EWF A;  4AZC A;  2MI7 A;  4JN4 A;  1I4L A;  2ALW A;  2F1A A;  1OA0 A;  3H0X A;  3KAV A;  1O7D B;  4FM3 A;  4DCN C;  4IWP A;  3BUQ A;  4UDY X;  4AZB A;  4IWQ A;  4EZZ A;  3D51 A;  2RAI A;  1U00 A;  4E81 A;  3ERC C;  3G9G A;  3UIT A;  1HTY A;  4KIK B;  3DQG A;  3DOB A;  4H8S A;  3DX0 A;  3BVX A;  1TQU A;  2GA9 D;  2OZN B;  4IW0 A;  2O0I 1;  4JWD A;  2YIV X;  4FZS A;  3D4Z A;  3CV5 A;  1QX1 A;  3DPQ A;  2F7Q A;  3KAW A;  3O3N B;  3ACO A;  3I01 A;  3DPP A;  3EJQ A;  2X3W A;  7HSC A;  5E84 A;  2FYV A;  1R5E A;  1UPX A;  2V0O A;  3RV0 A;  2BPR A;  3DDF A;  1SU8 A;  2X3V A;  1SU6 A;  4I43 A;  2YIB A;  1YUW A;  4WV7 A;  3T49 A;  3DX1 A;  2N3K A;  1URU A;  2RAJ A;  2JNK A;  2Z0N A;  4UDX X;  3PLT A;  4AZC B;  2YL6 A;  3BVW A;  3HAI A;  1CKR A;  2OBM A;  4FZP A;  2WYH A;  3BUD A;  3SYV A;  1X03 A;  2QFF A;  4JWC A;  3DX3 A;  3ER8 C;  4H6I A;  1TQS A;  2C08 A;  2OW7 A;  4MQD A;  3ABH A;  2V7Y A;  2YLL A;  4B9Q A;  4IM2 A;  3VEA A;  3L3O M;  3EJP A;  1R33 A;  4EZP A;  4EZX A;  3CZN A;  1QWN A;  4AZ6 A;  3D4Y A;  4H6H A;  3D2E A;  2D4C A;  4E3C A;  1BPR A;  3C7N A;  5C5B B;  2X3X A;  3FD9 A;  2OP6 A;  3B52 X;  1Q5L A;  1O7D C;  2NCZ A;  2LXY A;  3BUB A;  3DYT A;  1W9M A;  1OAO A;  1I49 A;  2D1L A;  3I39 X;  4AZH A;  4PO2 A;  2Q13 A;  2RAK A;  4M0M A;  3D50 A;  3BLB A;  1TQW A;  2QKW A;  3B53 X;  2JNS A;  3BVU A;  3KDR A;  2YKT A;  2QXL A;  4EZW A;  1ZWW A;  4F00 A;  1Y2O A;  4NQI A;  4NSW A;  4HYB A;  2OO2 A;  4JNF A;  3BUI A;  4WPE A;  1E1D A;  3Q84 A;  4EZS A;  1SUF A;  3OHX M;  3BVV A;  3DX2 A;  3DDG A;  4EZO A;  2YL8 A;  4AKV A;  3L3P A;  4EZY A;  3VKH A;  3OK8 A;  3RV1 A;  3VEB A;  1GNT A;  4EZT A;  2ZXQ A;  4ILH B;  3T48 A;  1DKZ A;  2EFL A;  4IM0 A;  3GI7 A;  4AZ7 A;  4EZQ A;  3HAH A;  3D2F A;  2OW6 A;  1GN9 A;  4IWO A;  3O3M B;  4FZO A;  3QA8 A;  2YIA A;  2F1B A;  2OBL A;  2ND0 A;  3D52 A;  3DX4 A;  3HAJ A;  2F7P A;  3EJT A;  3LLL A;  4FL9 A;  1DKY A;  4R5G A;  3EJS A;  3T4A G;  4R5J A;  3CVR A;  4HR1 A;  2YL9 A;  1SU7 A;  1GNL A;  3T47 A;  4EZU A;  4R5K A;  1OA1 A;  3LVT A;  3CKD A;  2KHO A;  2YI8 A;  4EZR A;  1E2U A;  3CAZ A;  3LMF A;  2WYI A;  3QNJ A;  3OWG A;  5KBP A;  1HWW A;  2YI9 A;  3M3W A;  4D8J A;  2Z8Y A;  4AZ5 A;  3QNI A;  3F7W A;  3QE6 A;  4AVM A;  1HXK A;  4NPH A;  3QWE A;  2PY6 A;  2RT6 A;  1WDZ A;  1X04 A;  2WIN M;  5FIG A;  3EJU A;  1I4D A;  1ZYL A;  1DKX A;  4EZN A;  2Z0V A;  4IM3 A;  2F7O A;  2FIC A;  3ZEF A;  2EFK A;  2Z0O A;  2YLA A;  1TQT A;  3SBS A;  4JNE A;  2ND1 A;  3ZED A;  2GF4 A;  2YL5 A;  4R5L A;  1DG4 A;  5C5B A;  3A98 A;  2F7R A;  3I2W A;  1PS3 A;  1I4T A;  4ILI A;  1E9V A;  4ILG A;  1LQ7 A;  4JL9 A;  1R34 A;  4KIK A;  3N8E A;  3SBT B;  4EZV A; 
#chains in the Genus database with same CATH homology
 2GAF D;  2OBL A;  3FD9 A;  2ND0 A;  4HR1 B;  5FLE X;  3DPQ A;  3KAW A;  3O3N B;  3I01 A;  3DPP A;  2OP6 A;  4FL9 A;  7HSC A;  1DKY A;  4R5G A;  5E84 A;  3T4A G;  1UPX A;  3RV0 A;  4R5J A;  3B52 X;  3I04 A;  1Q5L A;  2NCZ A;  3C7N B;  2BPR A;  4HR1 A;  2EX3 B;  1SU8 A;  1W9M A;  4WV5 A;  1OAO A;  4PO2 A;  3I39 X;  1SU7 A;  1GNL A;  3T47 A;  1SU6 A;  4EZU A;  3B51 X;  2YIB A;  1OA1 A;  4R5K A;  1YUW A;  4I43 A;  4G6Q A;  4M0M A;  4F01 A;  4JWE A;  4WV7 A;  3T49 A;  1MJG A;  3O3O B;  2KHO A;  2YI8 A;  4EZR A;  1E2U A;  2N3K A;  3B53 X;  3ER9 B;  3LMF A;  2JNS A;  4HY9 A;  4JWI A;  3QNJ A;  3OWG A;  4UDX X;  4JLC A;  3KDR A;  1JQK A;  2QXL A;  2YI9 A;  4R5I A;  4EZW A;  4F00 A;  4D8J A;  2Z8Y A;  4HYB A;  3T46 A;  3F7W A;  4JNF A;  2LM0 A;  3DPO A;  1CKR A;  2X5C A;  5TKY A;  2OBM A;  4NPH A;  2EWF A;  2PY6 A;  2QFF A;  1E1D A;  2RT6 A;  4JWC A;  4JN4 A;  4EZS A;  2WIN M;  1SUF A;  4H6I A;  3ER8 C;  5FIG A;  3OHX M;  4MQD A;  1ZYL A;  3H0X A;  1OA0 A;  1DKX A;  3KAV A;  4FM3 A;  4EZN A;  4EZO A;  2V7Y A;  4IWP A;  4UDY X;  4IM3 A;  4EZY A;  3VKH A;  4IWQ A;  4B9Q A;  3ZEF A;  4EZZ A;  3RV1 A;  3SBS A;  4JNE A;  1U00 A;  4E81 A;  1GNT A;  4IM2 A;  3VEB A;  3ERC C;  3VEA A;  3L3O M;  2ND1 A;  3UIT A;  4EZT A;  3ZED A;  4ILH B;  4KIK B;  4R5L A;  3T48 A;  3DQG A;  1DKZ A;  4IM0 A;  4EZP A;  4EZX A;  3DOB A;  3GI7 A;  1DG4 A;  3A98 A;  2GA9 D;  4H6H A;  4EZQ A;  4ILI A;  3D2E A;  1E9V A;  4ILG A;  3D2F A;  4IW0 A;  4JWD A;  2YIV X;  4JL9 A;  1GN9 A;  4KIK A;  4E3C A;  3N8E A;  4IWO A;  3O3M B;  3QA8 A;  1BPR A;  3SBT B;  3C7N A;  4EZV A;  2YIA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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