3DPQA

Crystal structure of the substrate binding domain of e. coli dnak in complex with a long pyrrhocoricin-derived inhibitor peptide (form b)
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
212
structure length
212
Chain Sequence
VLLLDVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLME
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Allosteric coupling between the lid and interdomain linker in DnaK revealed by inhibitor binding studies.
pubmed doi rcsb
molecule tags Chaperone, peptide binding protein
source organism Escherichia coli
molecule keywords Chaperone protein dnaK
total genus 52
structure length 212
sequence length 212
chains with identical sequence B, E, F
ec nomenclature
pdb deposition date 2008-07-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.10 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Substrate Binding Domain Of Dnak; Chain:A; Domain 2 3dpqA02
2.60.34.10 Mainly Beta Sandwich Substrate Binding Domain Of DNAk; Chain A, domain 1 Substrate Binding Domain Of DNAk; Chain A, domain 1 3dpqA01
1DG4A 5E84A 3QNJA 3DOBA 3H0XA 3C7NB 4JNFA 1BPRA 4EZQA 4R5JA 4EZZA 3T49A 2V7YA 1DKZA 7HSCA 5TKYA 2KHOA 4JWCA 4EZNA 4EZPA 4EZSA 4R5IA 2OP6A 2QFFA 4JNEA 3OHXM 3C7NA 4EZTA 4R5LA 1DKXA 4EZRA 3T46A 4JN4A 4B9QA 4WV7A 4HY9A 2QXLA 4EZXA 4F00A 3DPOA 4JWDA 1YUWA 3DPPA 3D2EA 4H6IA 4R5KA 4EZUA 4EZYA 1Q5LA 4HYBA 1DKYA 3T48A 4PO2A 4EZOA 4FL9A 4E81A 4R5GA 3N8EA 4JWEA 3DPQA 4EZWA 4WV5A 1U00A 3T47A 4H6HA 2WINM 4F01A 2BPRA 4JWIA 3L3OM 4EZVA 3D2FA 3T4AG 1CKRA 3DQGA
chains in the Genus database with same CATH superfamily
3QE6A 2GAFD 2YL8A 1HWWA 3KAVA 2F1AA 2RT6A 5C5BB 4ILIA 3Q84A 4B9QA 4EZXA 4DCNC 4AZ6A 4R5KA 1WDZA 2ND0A 3BVTA 4JL9A 3B53X 1JQKA 4BNEA 4UDXX 4IWPA 3LMFA 1QX1A 4KIKB 4FM3A 4JN4A 2F18A 2QXLA 3QNIA 4JWDA 5C5BA 2D4CA 1E2UA 2V0OA 2RAIA 2BPRA 1UPXA 2YL9A 1HXKA 1DG4A 3Q0KA 3DOBA 3EJTA 1Y2OA 4NQIA 4AZ7A 1TQTA 1ZWWA 3DYTA 7HSCA 4AZCB 4JWCA 2OW7A 3SBTB 2ZXQA 3GI7A 1DKYA 4KIKA 4E81A 3DX2A 3CZSA 4EZVA 1I49A 2O0I1 4ILGA 3KDRA 2Z0OA 4FZPA 3I39X 3BVXA 3HAHA 4AZGA 1X03A 4AZCA 1TQUA 2OW6A 3EJUA 3RV0A 3ZEDA 2Z0VA 3VEAA 2YI8A 4ILHB 2QFFA 4ATMA 1I4TA 3DX3A 3KAWA 4EZUA 2Z0NA 3L3PA 3VKHA 4H8SA 2JNSA 3HAJA 3B51X 1BPRA 3DX0A 1GNTA 3SYVA 3QA8A 3ER8C 4EZSA 4EZTA 3DPOA 3EJPA 3BLBA 3D2FA 1E9VA 3BVUA 3DX1A 2Q13A 3HAIA 3BVWA 3PLTA 2MI7A 2YL5A 2N3KA 1OA0A 4AZIA 5FIGA 3D52A 1R33A 4WV7A 2EFLA 3ER9B 3D50A 4AZBA 1R34A 2OBLA 1U00A 1O7DB 4F01A 3OK8A 1SU6A 2Z8YA 2RAJA 3ZEFA 1OAOA 2ND1A 3CKDA 3OHXM 1DKXA 4IWOA 3O3NB 2FYVA 3D4ZA 4EZOA 2OZNB 2YIAA 3T47A 2F1BA 3A98A 3EJQA 3BVVA 2PMRA 1MJGA 2V7YA 3VEBA 1GNLA 3RPMA 3CV5A 4HR1B 3BUBA 4JLCA 2YLAA 4WV5A 3DPQA 4MQDA 1QWNA 4FZOA 3QNJA 3C7NB 2YIVX 3SBSA 4AKVA 1DKZA 2GF4A 4E3CA 2YL6A 2OP6A 1I4LA 2EWFA 3ABHA 2ELBA 1YUWA 3D2EA 4HYBA 1TQWA 5FLEX 2FICA 3DX4A 2PY6A 2X3VA 3O3MB 3DQGA 2F7QA 4IM0A 2C08A 1TQVA 2F7PA 2F7RA 3LVTA 4EZNA 4M0MA 1TQSA 4AZ5A 2ALWA 3T46A 4WPCA 4AVMA 2WYHA 1ZYLA 3EJRA 3CZNA 4FL9A 4I43A 3BUQA 3ACOA 2EFKA 4IW0A 4JNFA 3BUPA 2QKWA 4EZQA 1I4DA 4EZZA 3BUIA 3T49A 3EJSA 4EZPA 4R5IA 4JNEA 4G6QA 4AZHA 4NPHA 3G9GA 1HTYA 3CVRA 3DPPA 4EZYA 3UITA 1YWMA 4R5GA 3I2WA 4H6HA 2X3XA 3D51A 4JWIA 4DYLA 3T4AG 2GA9D 5E84A 2JNKA 2YIBA 1W9MA 4EZRA 4IM2A 2X3WA 5KBPA 1Q5LA 4PO2A 2NCZA 2LXYA 3SOGA 2X5CA 3F7WA 4IWQA 2YKTA 4R5JA 3LLLA 2Q12A 1LQ7A 3FD9A 3M3WA 2WYIA 4R5LA 3BUDA 2F7OA 3O3OB 4IM3A 3RV1A 4WPEA 2D1LA 1URUA 3T48A 1OA1A 2WINM 2YI9A 3DDGA 2EX3B 2LM0A 1PS3A 1X04A 4NSWA 3CAZA 5TKYA 1R5EA 2YLLA 1QWUA 4HY9A 3D4YA 3H0XA 4H6IA 1SU7A 3OWGA 4FZSA 3DDFA 1SUFA 3QWEA 1SU8A 4I1QA 1O7DC 4HR1A 1CKRA 2OO2A 1E1DA 3I01A 3ERCC 2KHOA 3C7NA 3B52X 4UDYX 3I04A 4F00A 1GN9A 2RAKA 3N8EA 4JWEA 4EZWA 2OBMA 4D8JA 3L3OM
chains in the Genus database with same CATH topology
5E84A 2GAFD 3ZEDA 3VEAA 1MJGA 2V7YA 2YI8A 3KAVA 4ILHB 3VEBA 2QFFA 2RT6A 2YIBA 1W9MA 4ILIA 4EZRA 4IM2A 4B9QA 1GNLA 4EZXA 4HR1B 4R5KA 1Q5LA 3KAWA 4EZUA 4JLCA 4PO2A 2NCZA 3VKHA 4WV5A 3DPQA 4MQDA 2ND0A 4JL9A 3B53X 2JNSA 2X5CA 3F7WA 3QNJA 4IWQA 1JQKA 3B51X 3C7NB 2YIVX 1BPRA 3SBSA 1GNTA 4R5JA 4UDXX 4IWPA 1DKZA 3QA8A 3ER8C 4E3CA 4EZSA 3LMFA 3FD9A 2OP6A 4KIKB 4EZTA 4R5LA 2EWFA 4FM3A 4JN4A 2QXLA 3DPOA 3O3OB 4IM3A 4JWDA 3D2EA 1YUWA 3RV1A 4HYBA 3T48A 5FLEX 1OA1A 2PY6A 1E2UA 2WINM 2BPRA 1UPXA 2YI9A 3D2FA 2EX3B 3O3MB 3DQGA 1E9VA 2LM0A 4IM0A 1DG4A 3DOBA 7HSCA 4M0MA 5TKYA 4JWCA 4EZNA 2N3KA 1OA0A 5FIGA 3SBTB 3T46A 4WV7A 4HY9A 1ZYLA 3H0XA 4H6IA 3GI7A 3ER9B 1SU7A 3OWGA 1DKYA 4KIKA 1SUFA 4E81A 4FL9A 2OBLA 4I43A 1SU8A 1U00A 4F01A 4EZVA 1SU6A 4HR1A 1CKRA 2Z8YA 4ILGA 1E1DA 4IW0A 3KDRA 4JNFA 3I01A 3ZEFA 1OAOA 4EZQA 3ERCC 2ND1A 3I39X 4EZZA 3T49A 2KHOA 4EZPA 4R5IA 4JNEA 3OHXM 3C7NA 3B52X 4G6QA 4UDYX 1DKXA 4NPHA 4IWOA 3I04A 3O3NB 4F00A 3DPPA 4EZYA 1GN9A 3UITA 4EZOA 4R5GA 3N8EA 4JWEA 4EZWA 2OBMA 2YIAA 4D8JA 3T47A 4H6HA 3A98A 4JWIA 3L3OM 3RV0A 3T4AG 2GA9D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DG4 A;  5E84 A;  3QNJ A;  3DOB A;  3H0X A;  3C7N B;  4JNF A;  1BPR A;  4EZQ A;  4R5J A;  4EZZ A;  3T49 A;  2V7Y A;  1DKZ A;  7HSC A;  5TKY A;  2KHO A;  4JWC A;  4EZN A;  4EZP A;  4EZS A;  4R5I A;  2OP6 A;  2QFF A;  4JNE A;  3OHX M;  3C7N A;  4EZT A;  4R5L A;  1DKX A;  4EZR A;  3T46 A;  4JN4 A;  4B9Q A;  4WV7 A;  4HY9 A;  2QXL A;  4EZX A;  4F00 A;  3DPO A;  4JWD A;  1YUW A;  3DPP A;  3D2E A;  4H6I A;  4R5K A;  4EZU A;  4EZY A;  1Q5L A;  4HYB A;  1DKY A;  3T48 A;  4PO2 A;  4EZO A;  4FL9 A;  4E81 A;  4R5G A;  3N8E A;  4JWE A;  3DPQ A;  4EZW A;  4WV5 A;  1U00 A;  3T47 A;  4H6H A;  2WIN M;  4F01 A;  2BPR A;  4JWI A;  3L3O M;  4EZV A;  3D2F A;  3T4A G;  1CKR A;  3DQG A; 
#chains in the Genus database with same CATH topology
 3QE6 A;  2GAF D;  2YL8 A;  1HWW A;  3KAV A;  2F1A A;  2RT6 A;  5C5B B;  4ILI A;  3Q84 A;  4B9Q A;  4EZX A;  4DCN C;  4AZ6 A;  4R5K A;  1WDZ A;  2ND0 A;  3BVT A;  4JL9 A;  3B53 X;  1JQK A;  4BNE A;  4UDX X;  4IWP A;  3LMF A;  1QX1 A;  4KIK B;  4FM3 A;  4JN4 A;  2F18 A;  2QXL A;  3QNI A;  4JWD A;  5C5B A;  2D4C A;  1E2U A;  2V0O A;  2RAI A;  2BPR A;  1UPX A;  2YL9 A;  1HXK A;  1DG4 A;  3Q0K A;  3DOB A;  3EJT A;  1Y2O A;  4NQI A;  4AZ7 A;  1TQT A;  1ZWW A;  3DYT A;  7HSC A;  4AZC B;  4JWC A;  2OW7 A;  3SBT B;  2ZXQ A;  3GI7 A;  1DKY A;  4KIK A;  4E81 A;  3DX2 A;  3CZS A;  4EZV A;  1I49 A;  2O0I 1;  4ILG A;  3KDR A;  2Z0O A;  4FZP A;  3I39 X;  3BVX A;  3HAH A;  4AZG A;  1X03 A;  4AZC A;  1TQU A;  2OW6 A;  3EJU A;  3RV0 A;  3ZED A;  2Z0V A;  3VEA A;  2YI8 A;  4ILH B;  2QFF A;  4ATM A;  1I4T A;  3DX3 A;  3KAW A;  4EZU A;  2Z0N A;  3L3P A;  3VKH A;  4H8S A;  2JNS A;  3HAJ A;  3B51 X;  1BPR A;  3DX0 A;  1GNT A;  3SYV A;  3QA8 A;  3ER8 C;  4EZS A;  4EZT A;  3DPO A;  3EJP A;  3BLB A;  3D2F A;  1E9V A;  3BVU A;  3DX1 A;  2Q13 A;  3HAI A;  3BVW A;  3PLT A;  2MI7 A;  2YL5 A;  2N3K A;  1OA0 A;  4AZI A;  5FIG A;  3D52 A;  1R33 A;  4WV7 A;  2EFL A;  3ER9 B;  3D50 A;  4AZB A;  1R34 A;  2OBL A;  1U00 A;  1O7D B;  4F01 A;  3OK8 A;  1SU6 A;  2Z8Y A;  2RAJ A;  3ZEF A;  1OAO A;  2ND1 A;  3CKD A;  3OHX M;  1DKX A;  4IWO A;  3O3N B;  2FYV A;  3D4Z A;  4EZO A;  2OZN B;  2YIA A;  3T47 A;  2F1B A;  3A98 A;  3EJQ A;  3BVV A;  2PMR A;  1MJG A;  2V7Y A;  3VEB A;  1GNL A;  3RPM A;  3CV5 A;  4HR1 B;  3BUB A;  4JLC A;  2YLA A;  4WV5 A;  3DPQ A;  4MQD A;  1QWN A;  4FZO A;  3QNJ A;  3C7N B;  2YIV X;  3SBS A;  4AKV A;  1DKZ A;  2GF4 A;  4E3C A;  2YL6 A;  2OP6 A;  1I4L A;  2EWF A;  3ABH A;  2ELB A;  1YUW A;  3D2E A;  4HYB A;  1TQW A;  5FLE X;  2FIC A;  3DX4 A;  2PY6 A;  2X3V A;  3O3M B;  3DQG A;  2F7Q A;  4IM0 A;  2C08 A;  1TQV A;  2F7P A;  2F7R A;  3LVT A;  4EZN A;  4M0M A;  1TQS A;  4AZ5 A;  2ALW A;  3T46 A;  4WPC A;  4AVM A;  2WYH A;  1ZYL A;  3EJR A;  3CZN A;  4FL9 A;  4I43 A;  3BUQ A;  3ACO A;  2EFK A;  4IW0 A;  4JNF A;  3BUP A;  2QKW A;  4EZQ A;  1I4D A;  4EZZ A;  3BUI A;  3T49 A;  3EJS A;  4EZP A;  4R5I A;  4JNE A;  4G6Q A;  4AZH A;  4NPH A;  3G9G A;  1HTY A;  3CVR A;  3DPP A;  4EZY A;  3UIT A;  1YWM A;  4R5G A;  3I2W A;  4H6H A;  2X3X A;  3D51 A;  4JWI A;  4DYL A;  3T4A G;  2GA9 D;  5E84 A;  2JNK A;  2YIB A;  1W9M A;  4EZR A;  4IM2 A;  2X3W A;  5KBP A;  1Q5L A;  4PO2 A;  2NCZ A;  2LXY A;  3SOG A;  2X5C A;  3F7W A;  4IWQ A;  2YKT A;  4R5J A;  3LLL A;  2Q12 A;  1LQ7 A;  3FD9 A;  3M3W A;  2WYI A;  4R5L A;  3BUD A;  2F7O A;  3O3O B;  4IM3 A;  3RV1 A;  4WPE A;  2D1L A;  1URU A;  3T48 A;  1OA1 A;  2WIN M;  2YI9 A;  3DDG A;  2EX3 B;  2LM0 A;  1PS3 A;  1X04 A;  4NSW A;  3CAZ A;  5TKY A;  1R5E A;  2YLL A;  1QWU A;  4HY9 A;  3D4Y A;  3H0X A;  4H6I A;  1SU7 A;  3OWG A;  4FZS A;  3DDF A;  1SUF A;  3QWE A;  1SU8 A;  4I1Q A;  1O7D C;  4HR1 A;  1CKR A;  2OO2 A;  1E1D A;  3I01 A;  3ERC C;  2KHO A;  3C7N A;  3B52 X;  4UDY X;  3I04 A;  4F00 A;  1GN9 A;  2RAK A;  3N8E A;  4JWE A;  4EZW A;  2OBM A;  4D8J A;  3L3O M; 
#chains in the Genus database with same CATH homology
 5E84 A;  2GAF D;  3ZED A;  3VEA A;  1MJG A;  2V7Y A;  2YI8 A;  3KAV A;  4ILH B;  3VEB A;  2QFF A;  2RT6 A;  2YIB A;  1W9M A;  4ILI A;  4EZR A;  4IM2 A;  4B9Q A;  1GNL A;  4EZX A;  4HR1 B;  4R5K A;  1Q5L A;  3KAW A;  4EZU A;  4JLC A;  4PO2 A;  2NCZ A;  3VKH A;  4WV5 A;  3DPQ A;  4MQD A;  2ND0 A;  4JL9 A;  3B53 X;  2JNS A;  2X5C A;  3F7W A;  3QNJ A;  4IWQ A;  1JQK A;  3B51 X;  3C7N B;  2YIV X;  1BPR A;  3SBS A;  1GNT A;  4R5J A;  4UDX X;  4IWP A;  1DKZ A;  3QA8 A;  3ER8 C;  4E3C A;  4EZS A;  3LMF A;  3FD9 A;  2OP6 A;  4KIK B;  4EZT A;  4R5L A;  2EWF A;  4FM3 A;  4JN4 A;  2QXL A;  3DPO A;  3O3O B;  4IM3 A;  4JWD A;  3D2E A;  1YUW A;  3RV1 A;  4HYB A;  3T48 A;  5FLE X;  1OA1 A;  2PY6 A;  1E2U A;  2WIN M;  2BPR A;  1UPX A;  2YI9 A;  3D2F A;  2EX3 B;  3O3M B;  3DQG A;  1E9V A;  2LM0 A;  4IM0 A;  1DG4 A;  3DOB A;  7HSC A;  4M0M A;  5TKY A;  4JWC A;  4EZN A;  2N3K A;  1OA0 A;  5FIG A;  3SBT B;  3T46 A;  4WV7 A;  4HY9 A;  1ZYL A;  3H0X A;  4H6I A;  3GI7 A;  3ER9 B;  1SU7 A;  3OWG A;  1DKY A;  4KIK A;  1SUF A;  4E81 A;  4FL9 A;  2OBL A;  4I43 A;  1SU8 A;  1U00 A;  4F01 A;  4EZV A;  1SU6 A;  4HR1 A;  1CKR A;  2Z8Y A;  4ILG A;  1E1D A;  4IW0 A;  3KDR A;  4JNF A;  3I01 A;  3ZEF A;  1OAO A;  4EZQ A;  3ERC C;  2ND1 A;  3I39 X;  4EZZ A;  3T49 A;  2KHO A;  4EZP A;  4R5I A;  4JNE A;  3OHX M;  3C7N A;  3B52 X;  4G6Q A;  4UDY X;  1DKX A;  4NPH A;  4IWO A;  3I04 A;  3O3N B;  4F00 A;  3DPP A;  4EZY A;  1GN9 A;  3UIT A;  4EZO A;  4R5G A;  3N8E A;  4JWE A;  4EZW A;  2OBM A;  2YIA A;  4D8J A;  3T47 A;  4H6H A;  3A98 A;  4JWI A;  3L3O M;  3RV0 A;  3T4A G;  2GA9 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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