3DPOA

Crystal structure of the substrate binding domain of e. coli dnak in complex with a short pyrrhocoricin-derived inhibitor peptide
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
213
structure length
213
Chain Sequence
VLLLDVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLMEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Allosteric coupling between the lid and interdomain linker in DnaK revealed by inhibitor binding studies
pubmed doi rcsb
molecule tags Chaperone, peptide binding protein
source organism Escherichia coli
molecule keywords Chaperone protein dnaK
total genus 62
structure length 213
sequence length 213
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-07-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.10 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Substrate Binding Domain Of Dnak; Chain:A; Domain 2 3dpoA02
2.60.34.10 Mainly Beta Sandwich Substrate Binding Domain Of DNAk; Chain A, domain 1 Substrate Binding Domain Of DNAk; Chain A, domain 1 3dpoA01
4WV7A 2WINM 1YUWA 1DKYA 4R5JA 1DKXA 2QXLA 4JWCA 4R5KA 3DPQA 4JWEA 1CKRA 4E81A 4R5IA 3D2EA 4JNFA 4HY9A 3T48A 2OP6A 3D2FA 4EZWA 4FL9A 4EZYA 1DKZA 3DPPA 3DPOA 4EZXA 3DOBA 2KHOA 4WV5A 4JNEA 4R5LA 4JWDA 2QFFA 4PO2A 5E84A 2V7YA 4R5GA 4JWIA 3C7NA 1U00A 3L3OM 4H6HA 4EZUA 4EZRA 1DG4A 3N8EA 4EZZA 1Q5LA 3DQGA 3H0XA 4H6IA 4EZNA 3T47A 4EZSA 4B9QA 1BPRA 7HSCA 3T4AG 4EZVA 4EZOA 3QNJA 4HYBA 4F00A 2BPRA 4EZTA 3C7NB 4EZPA 5TKYA 3T49A 4JN4A 4F01A 4EZQA 3OHXM 3T46A
chains in the Genus database with same CATH superfamily
4IM0A 2NCZA 3DX3A 2F1AA 3ERCC 2D4CA 4FZOA 4IWOA 3DX1A 3T47A 3C7NB 2OW6A 1UPXA 3RPMA 5TKYA 1O7DB 3I39X 4EZQA 1R5EA 3D51A 1TQUA 1E2UA 1I4DA 3CKDA 2OO2A 1HWWA 2X3XA 5C5BB 3EJTA 2OBMA 4AZGA 3O3OB 3RV0A 4FZSA 1X03A 4KIKA 1JQKA 3D4ZA 2FYVA 2F7OA 1LQ7A 3CVRA 2EWFA 3DDFA 2ELBA 5C5BA 2QKWA 2JNSA 5FIGA 2F7RA 4DCNC 3M3WA 4H8SA 3LLLA 4AVMA 1U00A 2GA9D 4H6HA 2PMRA 3N8EA 4EZSA 3D50A 3ZEDA 4ILHB 1HTYA 3D52A 1CKRA 4AKVA 2F18A 4WPCA 2LM0A 4HR1B 1GNTA 3BVUA 3BUDA 3SYVA 1O7DC 3DQGA 3Q0KA 3L3PA 4NQIA 4F01A 3OHXM 4HR1A 2YL6A 4JWEA 1URUA 3D2FA 3KDRA 3DPPA 4BNEA 3ER9B 2C08A 2GF4A 2MI7A 1E9VA 4FM3A 3ZEFA 2X3VA 3LVTA 4HY9A 2RAKA 2F7QA 3I04A 1I49A 3BVWA 3L3OM 4AZBA 7HSCA 4EZVA 3B51X 3BUIA 4E3CA 2Z0VA 4IWQA 4KIKB 4FZPA 3LMFA 3DPQA 2O0I1 3KAVA 2X3WA 3CZSA 4WV5A 4R5LA 3BUBA 1SU8A 4JWIA 1OAOA 2YI9A 2EFLA 3F7WA 4EZOA 4JL9A 1QWUA 2ALWA 2YIAA 1DG4A 1MJGA 4FL9A 3O3NB 3DX0A 2F7PA 4EZUA 2X5CA 5KBPA 2ZXQA 2Q13A 3GI7A 2Z8YA 3T4AG 4HYBA 3QA8A 3QNIA 1I4TA 3CAZA 4WV7A 4R5JA 1GN9A 3EJSA 3SOGA 3PLTA 1OA1A 2QFFA 3BVVA 2V7YA 3I01A 4M0MA 4EZRA 2OZNB 3VEBA 1ZWWA 1Q5LA 3FD9A 3H0XA 4ILIA 4AZIA 4B9QA 2YIVX 4JN4A 2WYIA 2WINM 2RAIA 1DKYA 2QXLA 5FLEX 3UITA 4E81A 3EJQA 3HAJA 2YLAA 3DYTA 4IM3A 3G9GA 1PS3A 3RV1A 3OWGA 2F1BA 1HXKA 2V0OA 4ILGA 4IW0A 4R5KA 1DKXA 2OW7A 2Z0OA 3QWEA 1GNLA 2Z0NA 1I4LA 3D2EA 4IM2A 4AZ7A 4EZWA 2LXYA 3BLBA 2GAFD 1TQTA 2EX3B 2YL8A 2PY6A 3BVXA 1X04A 2Q12A 4I1QA 4AZHA 4I43A 1E1DA 4NSWA 3D4YA 3SBTB 3O3MB 3EJRA 1TQSA 4AZ5A 1ZYLA 1W9MA 4JNEA 3BVTA 2WYHA 4AZ6A 4G6QA 3VEAA 3KAWA 3ABHA 1R34A 3A98A 1BPRA 3QNJA 1Y2OA 2EFKA 3SBSA 2YIBA 1WDZA 4JWCA 4IWPA 2JNKA 3DDGA 4WPEA 3Q84A 4PO2A 3DX2A 3C7NA 3BUQA 4EZZA 3EJPA 1TQVA 2BPRA 1SU7A 2ND0A 4MQDA 3CZNA 1SU6A 4JLCA 4R5IA 2OP6A 4JNFA 4EZYA 1OA0A 1DKZA 3B53X 4JWDA 2YI8A 5E84A 4R5GA 3B52X 1QX1A 4UDYX 4F00A 4EZTA 2RAJA 3T49A 2FICA 3T46A 1R33A 1YWMA 4UDXX 3DX4A 3OK8A 3T48A 2ND1A 3I2WA 3DPOA 4EZXA 2KHOA 2D1LA 2RT6A 3BUPA 4AZCB 4EZNA 1QWNA 4EZPA 3ER8C 2YKTA 3HAIA 4DYLA 2N3KA 1YUWA 3EJUA 3ACOA 2YLLA 3VKHA 2YL5A 3CV5A 4D8JA 3DOBA 4AZCA 3HAHA 1TQWA 2OBLA 4H6IA 3QE6A 1SUFA 4ATMA 4NPHA 2YL9A
chains in the Genus database with same CATH topology
4WV7A 2YIBA 4R5JA 4HR1A 4JWCA 1GN9A 4IWPA 4JWEA 4IM0A 3D2FA 3KDRA 2NCZA 3DPPA 3ERCC 1OA1A 2QFFA 4PO2A 3ER9B 2V7YA 3I01A 3C7NA 4M0MA 4EZRA 4IWOA 3VEBA 4EZZA 1Q5LA 3FD9A 3H0XA 4ILIA 3T47A 4B9QA 2YIVX 2BPRA 3C7NB 1SU7A 1UPXA 2ND0A 4MQDA 5TKYA 4JN4A 3I39X 1E9VA 4FM3A 4EZQA 1SU6A 2WINM 3ZEFA 1DKYA 2QXLA 1E2UA 5FLEX 4JLCA 3UITA 4E81A 4R5IA 2OP6A 4JNFA 4HY9A 1OA0A 4EZYA 1DKZA 3I04A 4IM3A 3B53X 4JWDA 2OBMA 2YI8A 5E84A 3O3OB 4R5GA 3L3OM 3RV1A 3OWGA 3B52X 3RV0A 4KIKA 1JQKA 4ILGA 7HSCA 4EZVA 4UDYX 4F00A 4IW0A 3B51X 4EZTA 3T49A 4E3CA 4IWQA 3T46A 2EWFA 1DKXA 4KIKB 3LMFA 4R5KA 3DPQA 5FIGA 2JNSA 1GNLA 4UDXX 3KAVA 3D2EA 3T48A 4IM2A 4EZWA 2ND1A 3DPOA 2GAFD 4EZXA 4WV5A 2KHOA 4R5LA 2EX3B 2RT6A 1SU8A 4JWIA 1OAOA 1U00A 2PY6A 2GA9D 2YI9A 4H6HA 3N8EA 3F7WA 4EZNA 4EZSA 4EZOA 4I43A 4JL9A 1E1DA 3ZEDA 4ILHB 4EZPA 3ER8C 2YIAA 2N3KA 1DG4A 1YUWA 1CKRA 3SBTB 1MJGA 3O3MB 3VKHA 2LM0A 3O3NB 4FL9A 4HR1B 4D8JA 1ZYLA 1GNTA 1W9MA 3DOBA 4JNEA 4EZUA 4G6QA 3VEAA 3KAWA 2X5CA 2OBLA 3DQGA 4H6IA 3GI7A 2Z8YA 3A98A 1BPRA 3T4AG 3QNJA 4HYBA 3QA8A 1SUFA 4NPHA 4F01A 3OHXM 3SBSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WV7 A;  2WIN M;  1YUW A;  1DKY A;  4R5J A;  1DKX A;  2QXL A;  4JWC A;  4R5K A;  3DPQ A;  4JWE A;  1CKR A;  4E81 A;  4R5I A;  3D2E A;  4JNF A;  4HY9 A;  3T48 A;  2OP6 A;  3D2F A;  4EZW A;  4FL9 A;  4EZY A;  1DKZ A;  3DPP A;  3DPO A;  4EZX A;  3DOB A;  2KHO A;  4WV5 A;  4JNE A;  4R5L A;  4JWD A;  2QFF A;  4PO2 A;  5E84 A;  2V7Y A;  4R5G A;  4JWI A;  3C7N A;  1U00 A;  3L3O M;  4H6H A;  4EZU A;  4EZR A;  1DG4 A;  3N8E A;  4EZZ A;  1Q5L A;  3DQG A;  3H0X A;  4H6I A;  4EZN A;  3T47 A;  4EZS A;  4B9Q A;  1BPR A;  7HSC A;  3T4A G;  4EZV A;  4EZO A;  3QNJ A;  4HYB A;  4F00 A;  2BPR A;  4EZT A;  3C7N B;  4EZP A;  5TKY A;  3T49 A;  4JN4 A;  4F01 A;  4EZQ A;  3OHX M;  3T46 A; 
#chains in the Genus database with same CATH topology
 4IM0 A;  2NCZ A;  3DX3 A;  2F1A A;  3ERC C;  2D4C A;  4FZO A;  4IWO A;  3DX1 A;  3T47 A;  3C7N B;  2OW6 A;  1UPX A;  3RPM A;  5TKY A;  1O7D B;  3I39 X;  4EZQ A;  1R5E A;  3D51 A;  1TQU A;  1E2U A;  1I4D A;  3CKD A;  2OO2 A;  1HWW A;  2X3X A;  5C5B B;  3EJT A;  2OBM A;  4AZG A;  3O3O B;  3RV0 A;  4FZS A;  1X03 A;  4KIK A;  1JQK A;  3D4Z A;  2FYV A;  2F7O A;  1LQ7 A;  3CVR A;  2EWF A;  3DDF A;  2ELB A;  5C5B A;  2QKW A;  2JNS A;  5FIG A;  2F7R A;  4DCN C;  3M3W A;  4H8S A;  3LLL A;  4AVM A;  1U00 A;  2GA9 D;  4H6H A;  2PMR A;  3N8E A;  4EZS A;  3D50 A;  3ZED A;  4ILH B;  1HTY A;  3D52 A;  1CKR A;  4AKV A;  2F18 A;  4WPC A;  2LM0 A;  4HR1 B;  1GNT A;  3BVU A;  3BUD A;  3SYV A;  1O7D C;  3DQG A;  3Q0K A;  3L3P A;  4NQI A;  4F01 A;  3OHX M;  4HR1 A;  2YL6 A;  4JWE A;  1URU A;  3D2F A;  3KDR A;  3DPP A;  4BNE A;  3ER9 B;  2C08 A;  2GF4 A;  2MI7 A;  1E9V A;  4FM3 A;  3ZEF A;  2X3V A;  3LVT A;  4HY9 A;  2RAK A;  2F7Q A;  3I04 A;  1I49 A;  3BVW A;  3L3O M;  4AZB A;  7HSC A;  4EZV A;  3B51 X;  3BUI A;  4E3C A;  2Z0V A;  4IWQ A;  4KIK B;  4FZP A;  3LMF A;  3DPQ A;  2O0I 1;  3KAV A;  2X3W A;  3CZS A;  4WV5 A;  4R5L A;  3BUB A;  1SU8 A;  4JWI A;  1OAO A;  2YI9 A;  2EFL A;  3F7W A;  4EZO A;  4JL9 A;  1QWU A;  2ALW A;  2YIA A;  1DG4 A;  1MJG A;  4FL9 A;  3O3N B;  3DX0 A;  2F7P A;  4EZU A;  2X5C A;  5KBP A;  2ZXQ A;  2Q13 A;  3GI7 A;  2Z8Y A;  3T4A G;  4HYB A;  3QA8 A;  3QNI A;  1I4T A;  3CAZ A;  4WV7 A;  4R5J A;  1GN9 A;  3EJS A;  3SOG A;  3PLT A;  1OA1 A;  2QFF A;  3BVV A;  2V7Y A;  3I01 A;  4M0M A;  4EZR A;  2OZN B;  3VEB A;  1ZWW A;  1Q5L A;  3FD9 A;  3H0X A;  4ILI A;  4AZI A;  4B9Q A;  2YIV X;  4JN4 A;  2WYI A;  2WIN M;  2RAI A;  1DKY A;  2QXL A;  5FLE X;  3UIT A;  4E81 A;  3EJQ A;  3HAJ A;  2YLA A;  3DYT A;  4IM3 A;  3G9G A;  1PS3 A;  3RV1 A;  3OWG A;  2F1B A;  1HXK A;  2V0O A;  4ILG A;  4IW0 A;  4R5K A;  1DKX A;  2OW7 A;  2Z0O A;  3QWE A;  1GNL A;  2Z0N A;  1I4L A;  3D2E A;  4IM2 A;  4AZ7 A;  4EZW A;  2LXY A;  3BLB A;  2GAF D;  1TQT A;  2EX3 B;  2YL8 A;  2PY6 A;  3BVX A;  1X04 A;  2Q12 A;  4I1Q A;  4AZH A;  4I43 A;  1E1D A;  4NSW A;  3D4Y A;  3SBT B;  3O3M B;  3EJR A;  1TQS A;  4AZ5 A;  1ZYL A;  1W9M A;  4JNE A;  3BVT A;  2WYH A;  4AZ6 A;  4G6Q A;  3VEA A;  3KAW A;  3ABH A;  1R34 A;  3A98 A;  1BPR A;  3QNJ A;  1Y2O A;  2EFK A;  3SBS A;  2YIB A;  1WDZ A;  4JWC A;  4IWP A;  2JNK A;  3DDG A;  4WPE A;  3Q84 A;  4PO2 A;  3DX2 A;  3C7N A;  3BUQ A;  4EZZ A;  3EJP A;  1TQV A;  2BPR A;  1SU7 A;  2ND0 A;  4MQD A;  3CZN A;  1SU6 A;  4JLC A;  4R5I A;  2OP6 A;  4JNF A;  4EZY A;  1OA0 A;  1DKZ A;  3B53 X;  4JWD A;  2YI8 A;  5E84 A;  4R5G A;  3B52 X;  1QX1 A;  4UDY X;  4F00 A;  4EZT A;  2RAJ A;  3T49 A;  2FIC A;  3T46 A;  1R33 A;  1YWM A;  4UDX X;  3DX4 A;  3OK8 A;  3T48 A;  2ND1 A;  3I2W A;  3DPO A;  4EZX A;  2KHO A;  2D1L A;  2RT6 A;  3BUP A;  4AZC B;  4EZN A;  1QWN A;  4EZP A;  3ER8 C;  2YKT A;  3HAI A;  4DYL A;  2N3K A;  1YUW A;  3EJU A;  3ACO A;  2YLL A;  3VKH A;  2YL5 A;  3CV5 A;  4D8J A;  3DOB A;  4AZC A;  3HAH A;  1TQW A;  2OBL A;  4H6I A;  3QE6 A;  1SUF A;  4ATM A;  4NPH A;  2YL9 A; 
#chains in the Genus database with same CATH homology
 4WV7 A;  2YIB A;  4R5J A;  4HR1 A;  4JWC A;  1GN9 A;  4IWP A;  4JWE A;  4IM0 A;  3D2F A;  3KDR A;  2NCZ A;  3DPP A;  3ERC C;  1OA1 A;  2QFF A;  4PO2 A;  3ER9 B;  2V7Y A;  3I01 A;  3C7N A;  4M0M A;  4EZR A;  4IWO A;  3VEB A;  4EZZ A;  1Q5L A;  3FD9 A;  3H0X A;  4ILI A;  3T47 A;  4B9Q A;  2YIV X;  2BPR A;  3C7N B;  1SU7 A;  1UPX A;  2ND0 A;  4MQD A;  5TKY A;  4JN4 A;  3I39 X;  1E9V A;  4FM3 A;  4EZQ A;  1SU6 A;  2WIN M;  3ZEF A;  1DKY A;  2QXL A;  1E2U A;  5FLE X;  4JLC A;  3UIT A;  4E81 A;  4R5I A;  2OP6 A;  4JNF A;  4HY9 A;  1OA0 A;  4EZY A;  1DKZ A;  3I04 A;  4IM3 A;  3B53 X;  4JWD A;  2OBM A;  2YI8 A;  5E84 A;  3O3O B;  4R5G A;  3L3O M;  3RV1 A;  3OWG A;  3B52 X;  3RV0 A;  4KIK A;  1JQK A;  4ILG A;  7HSC A;  4EZV A;  4UDY X;  4F00 A;  4IW0 A;  3B51 X;  4EZT A;  3T49 A;  4E3C A;  4IWQ A;  3T46 A;  2EWF A;  1DKX A;  4KIK B;  3LMF A;  4R5K A;  3DPQ A;  5FIG A;  2JNS A;  1GNL A;  4UDX X;  3KAV A;  3D2E A;  3T48 A;  4IM2 A;  4EZW A;  2ND1 A;  3DPO A;  2GAF D;  4EZX A;  4WV5 A;  2KHO A;  4R5L A;  2EX3 B;  2RT6 A;  1SU8 A;  4JWI A;  1OAO A;  1U00 A;  2PY6 A;  2GA9 D;  2YI9 A;  4H6H A;  3N8E A;  3F7W A;  4EZN A;  4EZS A;  4EZO A;  4I43 A;  4JL9 A;  1E1D A;  3ZED A;  4ILH B;  4EZP A;  3ER8 C;  2YIA A;  2N3K A;  1DG4 A;  1YUW A;  1CKR A;  3SBT B;  1MJG A;  3O3M B;  3VKH A;  2LM0 A;  3O3N B;  4FL9 A;  4HR1 B;  4D8J A;  1ZYL A;  1GNT A;  1W9M A;  3DOB A;  4JNE A;  4EZU A;  4G6Q A;  3VEA A;  3KAW A;  2X5C A;  2OBL A;  3DQG A;  4H6I A;  3GI7 A;  2Z8Y A;  3A98 A;  1BPR A;  3T4A G;  3QNJ A;  4HYB A;  3QA8 A;  1SUF A;  4NPH A;  4F01 A;  3OHX M;  3SBS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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