4E81A

Crystal structure of the substrate binding domain of e.coli dnak in complex with a short apidaecin peptide
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
214
structure length
214
Chain Sequence
VLLLDVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLMEIA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Api88 is a novel antibacterial designer Peptide to treat systemic infections with multidrug-resistant gram-negative pathogens.
pubmed doi rcsb
molecule tags Chaperone
source organism Escherichia coli
molecule keywords Chaperone protein DnaK
total genus 63
structure length 214
sequence length 214
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-03-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.10 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Substrate Binding Domain Of Dnak; Chain:A; Domain 2 4e81A02
2.60.34.10 Mainly Beta Sandwich Substrate Binding Domain Of DNAk; Chain A, domain 1 Substrate Binding Domain Of DNAk; Chain A, domain 1 4e81A01
4E81A 4R5JA 5E84A 2V7YA 3T4AG 1BPRA 7HSCA 4JNEA 1U00A 3DPOA 2QXLA 3DPQA 4R5IA 4F01A 3N8EA 1YUWA 3T49A 3C7NA 2QFFA 4JN4A 4JWIA 4R5KA 4F00A 1DKZA 4FL9A 3T48A 4EZRA 4JWDA 4R5GA 4JNFA 4PO2A 4EZXA 1Q5LA 3D2EA 4EZWA 1DKXA 4HY9A 1DKYA 4EZPA 4EZSA 3C7NB 3OHXM 4EZNA 3T47A 4EZVA 4EZUA 2BPRA 4EZTA 4JWEA 2OP6A 4HYBA 4EZZA 4EZOA 4EZYA 4WV5A 4WV7A 2KHOA 3QNJA 1DG4A 1CKRA 2WINM 3DQGA 4EZQA 3D2FA 3DPPA 3L3OM 4H6IA 3T46A 4H6HA 5TKYA 4JWCA 3DOBA 4R5LA 3H0XA 4B9QA
chains in the Genus database with same CATH superfamily
2V0OA 5KBPA 2QFFA 2Z8YA 4JN4A 3D52A 4FZOA 2ALWA 2EFLA 2ZXQA 4UDYX 1DKXA 1SU7A 3G9GA 3BVXA 4EZVA 2OP6A 3BUIA 3BLBA 5TKYA 1R33A 1OA1A 1BPRA 3I01A 3T49A 3GI7A 5FLEX 2PY6A 3HAIA 2YLLA 1MJGA 2JNKA 2Q13A 2YI9A 2YIVX 2QXLA 3DPQA 4IW0A 1E9VA 3CZSA 2YIBA 4AVMA 3BUDA 3OHXM 5C5BB 3VEAA 4WPEA 2EX3B 3DDFA 1GN9A 4EZQA 4UDXX 2D4CA 4DCNC 1W9MA 3QE6A 1YUWA 1QWNA 2YIAA 3CV5A 2FYVA 3BUQA 4G6QA 4EZRA 2ELBA 5C5BA 3BUPA 4EZSA 2X3WA 3ACOA 3CZNA 3LLLA 1SU6A 3QWEA 4DYLA 3EJRA 1E1DA 4F00A 4JWDA 4AKVA 4ILGA 2MI7A 1PS3A 2WYHA 2OW7A 1OA0A 4EZUA 3I39X 4WV7A 3I2WA 2RAJA 3QNIA 3DPPA 2D1LA 4KIKA 4AZ6A 2X5CA 5E84A 1TQVA 4AZBA 3LMFA 1JQKA 3Q0KA 1WDZA 1TQWA 2RAKA 1X03A 4BNEA 3PLTA 4HYBA 2YL9A 2ND0A 2ND1A 4I1QA 1Y2OA 3F7WA 4H6IA 1I4DA 4R5JA 1HTYA 3DPOA 4FZPA 2EWFA 4EZPA 1ZWWA 3C7NB 4M0MA 3SYVA 4FZSA 2OZNB 4IWPA 4EZTA 4EZZA 1OAOA 4NQIA 3FD9A 3HAHA 2V7YA 3T4AG 2C08A 3A98A 4AZCB 3RV0A 3O3NB 3C7NA 3OK8A 3O3OB 4R5KA 1QX1A 3B52X 4EZXA 2Z0VA 3DDGA 2OBMA 3BVTA 2X3XA 2WINM 4AZCA 4WV5A 3DOBA 3CVRA 3ZEFA 4H8SA 3EJSA 3N8EA 3DX0A 1GNTA 1Q5LA 4EZNA 3DYTA 3QA8A 4NPHA 3ABHA 4EZYA 2YI8A 1E2UA 2N3KA 3L3OM 2F1AA 1LQ7A 4ILIA 4B9QA 3O3MB 3SOGA 2RAIA 2PMRA 2LM0A 2GA9D 2X3VA 3B51X 4KIKB 4PO2A 2GF4A 2OO2A 1R34A 1SU8A 4JWEA 3CKDA 5FIGA 1O7DC 1UPXA 3KAWA 4H6HA 3ERCC 3EJTA 4AZ7A 1HWWA 3D4ZA 3BVUA 2JNSA 4JWIA 4JNFA 1I49A 4HY9A 2QKWA 1URUA 2YL5A 2F7QA 3D51A 4EZOA 4IM0A 3VKHA 3SBSA 7HSCA 2Z0NA 3DX4A 4ATMA 3ER8C 3BUBA 2F7RA 3B53X 4AZIA 1DKZA 4MQDA 2F18A 3KAVA 3BVVA 2OW6A 4AZHA 3SBTB 3CAZA 2BPRA 2F7PA 1YWMA 2KHOA 3QNJA 1DG4A 4AZGA 4IM2A 2FICA 2LXYA 1I4LA 1HXKA 4F01A 4I43A 3VEBA 4R5GA 3KDRA 1GNLA 3UITA 1SUFA 1DKYA 1I4TA 4IWQA 2O0I1 4NSWA 1TQTA 2F1BA 3DX3A 2YLAA 4JWCA 3Q84A 4E81A 1QWUA 4JNEA 1R5EA 4R5IA 3ER9B 3T48A 3I04A 1X04A 2WYIA 3D2EA 2Q12A 2YKTA 3OWGA 3ZEDA 3DX2A 1CKRA 3DQGA 2GAFD 4FM3A 4HR1B 3EJUA 2YL8A 1U00A 2Z0OA 3RPMA 4JL9A 4WPCA 3D50A 4EZWA 2RT6A 2YL6A 4HR1A 3D4YA 3L3PA 1TQUA 4FL9A 2F7OA 2NCZA 2EFKA 4D8JA 1ZYLA 3RV1A 4JLCA 2OBLA 3M3WA 4E3CA 4IM3A 3EJPA 3LVTA 1TQSA 3HAJA 3EJQA 4IWOA 3BVWA 3T47A 4AZ5A 1O7DB 3DX1A 4ILHB 3D2FA 3T46A 3H0XA 4R5LA
chains in the Genus database with same CATH topology
4F01A 1E1DA 3N8EA 2QFFA 2Z8YA 4I43A 4JN4A 3VEBA 4F00A 4JWDA 4R5GA 1GNTA 4ILGA 3KDRA 1GNLA 3UITA 1Q5LA 1SUFA 4UDYX 1DKXA 1DKYA 1SU7A 4EZNA 1OA0A 4EZVA 4EZUA 3I39X 3QA8A 4IWQA 2OP6A 4NPHA 4WV7A 4EZYA 2YI8A 1E2UA 2N3KA 3L3OM 3DPPA 3DOBA 5TKYA 4JWCA 4KIKA 4B9QA 4ILIA 1OA1A 2X5CA 3O3MB 5E84A 4E81A 1BPRA 4JNEA 4R5IA 3I01A 3T49A 3GI7A 3LMFA 2LM0A 2GA9D 3B51X 3ER9B 1JQKA 3T48A 4KIKB 5FLEX 2PY6A 3I04A 4PO2A 3D2EA 1SU8A 1MJGA 4JWEA 3OWGA 4HYBA 3ZEDA 2ND0A 2ND1A 5FIGA 1CKRA 3DQGA 1UPXA 3KAWA 3F7WA 4H6IA 2GAFD 4H6HA 2YI9A 4FM3A 4HR1B 2YIVX 4R5JA 3ERCC 1U00A 3DPOA 2QXLA 3DPQA 4JL9A 4IW0A 2JNSA 4JWIA 1E9VA 2YIBA 4JNFA 2EWFA 4HY9A 4EZWA 4EZPA 3C7NB 3OHXM 2RT6A 4M0MA 4HR1A 4IWPA 4EZTA 4EZZA 4EZOA 1OAOA 4IM0A 3VEAA 2EX3B 4EZQA 1GN9A 3VKHA 3SBSA 4FL9A 3FD9A 2NCZA 7HSCA 4UDXX 3ER8C 4D8JA 1ZYLA 2V7YA 3T4AG 3RV1A 1W9MA 4JLCA 2OBLA 3B53X 3A98A 4E3CA 1YUWA 4IM3A 3RV0A 3O3NB 2YIAA 3C7NA 3O3OB 4R5KA 1DKZA 4G6QA 4EZRA 4MQDA 3KAVA 3B52X 4EZXA 3SBTB 4EZSA 4IWOA 2OBMA 3T47A 2BPRA 1SU6A 2KHOA 3QNJA 1DG4A 2WINM 4ILHB 3D2FA 3T46A 4WV5A 3H0XA 4IM2A 4R5LA 3ZEFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E81 A;  4R5J A;  5E84 A;  2V7Y A;  3T4A G;  1BPR A;  7HSC A;  4JNE A;  1U00 A;  3DPO A;  2QXL A;  3DPQ A;  4R5I A;  4F01 A;  3N8E A;  1YUW A;  3T49 A;  3C7N A;  2QFF A;  4JN4 A;  4JWI A;  4R5K A;  4F00 A;  1DKZ A;  4FL9 A;  3T48 A;  4EZR A;  4JWD A;  4R5G A;  4JNF A;  4PO2 A;  4EZX A;  1Q5L A;  3D2E A;  4EZW A;  1DKX A;  4HY9 A;  1DKY A;  4EZP A;  4EZS A;  3C7N B;  3OHX M;  4EZN A;  3T47 A;  4EZV A;  4EZU A;  2BPR A;  4EZT A;  4JWE A;  2OP6 A;  4HYB A;  4EZZ A;  4EZO A;  4EZY A;  4WV5 A;  4WV7 A;  2KHO A;  3QNJ A;  1DG4 A;  1CKR A;  2WIN M;  3DQG A;  4EZQ A;  3D2F A;  3DPP A;  3L3O M;  4H6I A;  3T46 A;  4H6H A;  5TKY A;  4JWC A;  3DOB A;  4R5L A;  3H0X A;  4B9Q A; 
#chains in the Genus database with same CATH topology
 2V0O A;  5KBP A;  2QFF A;  2Z8Y A;  4JN4 A;  3D52 A;  4FZO A;  2ALW A;  2EFL A;  2ZXQ A;  4UDY X;  1DKX A;  1SU7 A;  3G9G A;  3BVX A;  4EZV A;  2OP6 A;  3BUI A;  3BLB A;  5TKY A;  1R33 A;  1OA1 A;  1BPR A;  3I01 A;  3T49 A;  3GI7 A;  5FLE X;  2PY6 A;  3HAI A;  2YLL A;  1MJG A;  2JNK A;  2Q13 A;  2YI9 A;  2YIV X;  2QXL A;  3DPQ A;  4IW0 A;  1E9V A;  3CZS A;  2YIB A;  4AVM A;  3BUD A;  3OHX M;  5C5B B;  3VEA A;  4WPE A;  2EX3 B;  3DDF A;  1GN9 A;  4EZQ A;  4UDX X;  2D4C A;  4DCN C;  1W9M A;  3QE6 A;  1YUW A;  1QWN A;  2YIA A;  3CV5 A;  2FYV A;  3BUQ A;  4G6Q A;  4EZR A;  2ELB A;  5C5B A;  3BUP A;  4EZS A;  2X3W A;  3ACO A;  3CZN A;  3LLL A;  1SU6 A;  3QWE A;  4DYL A;  3EJR A;  1E1D A;  4F00 A;  4JWD A;  4AKV A;  4ILG A;  2MI7 A;  1PS3 A;  2WYH A;  2OW7 A;  1OA0 A;  4EZU A;  3I39 X;  4WV7 A;  3I2W A;  2RAJ A;  3QNI A;  3DPP A;  2D1L A;  4KIK A;  4AZ6 A;  2X5C A;  5E84 A;  1TQV A;  4AZB A;  3LMF A;  1JQK A;  3Q0K A;  1WDZ A;  1TQW A;  2RAK A;  1X03 A;  4BNE A;  3PLT A;  4HYB A;  2YL9 A;  2ND0 A;  2ND1 A;  4I1Q A;  1Y2O A;  3F7W A;  4H6I A;  1I4D A;  4R5J A;  1HTY A;  3DPO A;  4FZP A;  2EWF A;  4EZP A;  1ZWW A;  3C7N B;  4M0M A;  3SYV A;  4FZS A;  2OZN B;  4IWP A;  4EZT A;  4EZZ A;  1OAO A;  4NQI A;  3FD9 A;  3HAH A;  2V7Y A;  3T4A G;  2C08 A;  3A98 A;  4AZC B;  3RV0 A;  3O3N B;  3C7N A;  3OK8 A;  3O3O B;  4R5K A;  1QX1 A;  3B52 X;  4EZX A;  2Z0V A;  3DDG A;  2OBM A;  3BVT A;  2X3X A;  2WIN M;  4AZC A;  4WV5 A;  3DOB A;  3CVR A;  3ZEF A;  4H8S A;  3EJS A;  3N8E A;  3DX0 A;  1GNT A;  1Q5L A;  4EZN A;  3DYT A;  3QA8 A;  4NPH A;  3ABH A;  4EZY A;  2YI8 A;  1E2U A;  2N3K A;  3L3O M;  2F1A A;  1LQ7 A;  4ILI A;  4B9Q A;  3O3M B;  3SOG A;  2RAI A;  2PMR A;  2LM0 A;  2GA9 D;  2X3V A;  3B51 X;  4KIK B;  4PO2 A;  2GF4 A;  2OO2 A;  1R34 A;  1SU8 A;  4JWE A;  3CKD A;  5FIG A;  1O7D C;  1UPX A;  3KAW A;  4H6H A;  3ERC C;  3EJT A;  4AZ7 A;  1HWW A;  3D4Z A;  3BVU A;  2JNS A;  4JWI A;  4JNF A;  1I49 A;  4HY9 A;  2QKW A;  1URU A;  2YL5 A;  2F7Q A;  3D51 A;  4EZO A;  4IM0 A;  3VKH A;  3SBS A;  7HSC A;  2Z0N A;  3DX4 A;  4ATM A;  3ER8 C;  3BUB A;  2F7R A;  3B53 X;  4AZI A;  1DKZ A;  4MQD A;  2F18 A;  3KAV A;  3BVV A;  2OW6 A;  4AZH A;  3SBT B;  3CAZ A;  2BPR A;  2F7P A;  1YWM A;  2KHO A;  3QNJ A;  1DG4 A;  4AZG A;  4IM2 A;  2FIC A;  2LXY A;  1I4L A;  1HXK A;  4F01 A;  4I43 A;  3VEB A;  4R5G A;  3KDR A;  1GNL A;  3UIT A;  1SUF A;  1DKY A;  1I4T A;  4IWQ A;  2O0I 1;  4NSW A;  1TQT A;  2F1B A;  3DX3 A;  2YLA A;  4JWC A;  3Q84 A;  4E81 A;  1QWU A;  4JNE A;  1R5E A;  4R5I A;  3ER9 B;  3T48 A;  3I04 A;  1X04 A;  2WYI A;  3D2E A;  2Q12 A;  2YKT A;  3OWG A;  3ZED A;  3DX2 A;  1CKR A;  3DQG A;  2GAF D;  4FM3 A;  4HR1 B;  3EJU A;  2YL8 A;  1U00 A;  2Z0O A;  3RPM A;  4JL9 A;  4WPC A;  3D50 A;  4EZW A;  2RT6 A;  2YL6 A;  4HR1 A;  3D4Y A;  3L3P A;  1TQU A;  4FL9 A;  2F7O A;  2NCZ A;  2EFK A;  4D8J A;  1ZYL A;  3RV1 A;  4JLC A;  2OBL A;  3M3W A;  4E3C A;  4IM3 A;  3EJP A;  3LVT A;  1TQS A;  3HAJ A;  3EJQ A;  4IWO A;  3BVW A;  3T47 A;  4AZ5 A;  1O7D B;  3DX1 A;  4ILH B;  3D2F A;  3T46 A;  3H0X A;  4R5L A; 
#chains in the Genus database with same CATH homology
 4F01 A;  1E1D A;  3N8E A;  2QFF A;  2Z8Y A;  4I43 A;  4JN4 A;  3VEB A;  4F00 A;  4JWD A;  4R5G A;  1GNT A;  4ILG A;  3KDR A;  1GNL A;  3UIT A;  1Q5L A;  1SUF A;  4UDY X;  1DKX A;  1DKY A;  1SU7 A;  4EZN A;  1OA0 A;  4EZV A;  4EZU A;  3I39 X;  3QA8 A;  4IWQ A;  2OP6 A;  4NPH A;  4WV7 A;  4EZY A;  2YI8 A;  1E2U A;  2N3K A;  3L3O M;  3DPP A;  3DOB A;  5TKY A;  4JWC A;  4KIK A;  4B9Q A;  4ILI A;  1OA1 A;  2X5C A;  3O3M B;  5E84 A;  4E81 A;  1BPR A;  4JNE A;  4R5I A;  3I01 A;  3T49 A;  3GI7 A;  3LMF A;  2LM0 A;  2GA9 D;  3B51 X;  3ER9 B;  1JQK A;  3T48 A;  4KIK B;  5FLE X;  2PY6 A;  3I04 A;  4PO2 A;  3D2E A;  1SU8 A;  1MJG A;  4JWE A;  3OWG A;  4HYB A;  3ZED A;  2ND0 A;  2ND1 A;  5FIG A;  1CKR A;  3DQG A;  1UPX A;  3KAW A;  3F7W A;  4H6I A;  2GAF D;  4H6H A;  2YI9 A;  4FM3 A;  4HR1 B;  2YIV X;  4R5J A;  3ERC C;  1U00 A;  3DPO A;  2QXL A;  3DPQ A;  4JL9 A;  4IW0 A;  2JNS A;  4JWI A;  1E9V A;  2YIB A;  4JNF A;  2EWF A;  4HY9 A;  4EZW A;  4EZP A;  3C7N B;  3OHX M;  2RT6 A;  4M0M A;  4HR1 A;  4IWP A;  4EZT A;  4EZZ A;  4EZO A;  1OAO A;  4IM0 A;  3VEA A;  2EX3 B;  4EZQ A;  1GN9 A;  3VKH A;  3SBS A;  4FL9 A;  3FD9 A;  2NCZ A;  7HSC A;  4UDX X;  3ER8 C;  4D8J A;  1ZYL A;  2V7Y A;  3T4A G;  3RV1 A;  1W9M A;  4JLC A;  2OBL A;  3B53 X;  3A98 A;  4E3C A;  1YUW A;  4IM3 A;  3RV0 A;  3O3N B;  2YIA A;  3C7N A;  3O3O B;  4R5K A;  1DKZ A;  4G6Q A;  4EZR A;  4MQD A;  3KAV A;  3B52 X;  4EZX A;  3SBT B;  4EZS A;  4IWO A;  2OBM A;  3T47 A;  2BPR A;  1SU6 A;  2KHO A;  3QNJ A;  1DG4 A;  2WIN M;  4ILH B;  3D2F A;  3T46 A;  4WV5 A;  3H0X A;  4IM2 A;  4R5L A;  3ZEF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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