4E81A

Crystal structure of the substrate binding domain of e.coli dnak in complex with a short apidaecin peptide
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
214
structure length
214
Chain Sequence
VLLLDVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLMEIA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Chaperone
source organism Escherichia coli
publication title Api88 is a novel antibacterial designer Peptide to treat systemic infections with multidrug-resistant gram-negative pathogens.
pubmed doi rcsb
molecule keywords Chaperone protein DnaK
total genus 63
structure length 214
sequence length 214
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-03-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.10 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Substrate Binding Domain Of Dnak; Chain:A; Domain 2 4e81A02
2.60.34.10 Mainly Beta Sandwich Substrate Binding Domain Of DNAk; Chain A, domain 1 Substrate Binding Domain Of DNAk; Chain A, domain 1 4e81A01
4EZPA 4EZNA 1DKZA 3T47A 4EZOA 2BPRA 3DPQA 3DPOA 1U00A 4JWCA 4R5GA 4R5IA 3DQGA 4EZVA 1YUWA 3N8EA 4HYBA 3D2FA 4R5KA 4JWEA 4B9QA 3T48A 5TKYA 4EZZA 4EZYA 3T49A 4EZSA 4PO2A 4JWDA 1Q5LA 4EZUA 5E84A 4F00A 2KHOA 1BPRA 4E81A 1DKXA 3C7NB 4EZTA 4FL9A 3T46A 4EZQA 2WINM 4WV7A 4EZXA 4R5JA 3D2EA 4H6IA 4JNFA 1CKRA 4JN4A 4JNEA 3H0XA 4H6HA 1DG4A 3L3OM 4F01A 2V7YA 4EZRA 4R5LA 2QFFA 3DOBA 1DKYA 3T4AG 4EZWA 2OP6A 3QNJA 7HSCA 4HY9A 3DPPA 4WV5A 3OHXM 4JWIA 3C7NA 2QXLA
chains in the Genus database with same CATH superfamily
4IW0A 3CV5A 2O0I1 3D4YA 3I2WA 2F18A 3CZNA 2ELBA 4AKVA 2JNKA 2WYHA 2N3KA 3BUIA 2FICA 1I49A 3BUPA 4NPHA 4JWCA 1ZYLA 3ZEFA 3G9GA 1JQKA 2WINM 4H6IA 3KDRA 1QX1A 4H6HA 2YI9A 4HR1A 3QNJA 3Q0KA 4HY9A 2F7OA 3UITA 4AZCA 4EZPA 3PLTA 3T47A 2GF4A 4I43A 2GA9D 2LXYA 1OA0A 3QE6A 4E81A 2YL8A 4FL9A 3T46A 3SOGA 2NCZA 3CZSA 4JNEA 2Z0NA 2QKWA 2YI8A 2OO2A 2F1BA 3ER8C 4EZVA 3BVVA 4EZYA 3T48A 2OW6A 4WPCA 4AZGA 2OZNB 1SU7A 4E3CA 4MQDA 4DYLA 1U00A 2Q12A 1YUWA 2OBMA 3D2FA 5TKYA 3OK8A 4JWDA 4ILGA 1ZWWA 1W9MA 1R5EA 3BUQA 3OWGA 2EX3B 3D50A 3H0XA 5C5BB 4AZ6A 1PS3A 3DDFA 3HAJA 3BUDA 1MJGA 3DPPA 3OHXM 3SYVA 1QWUA 1SUFA 1OAOA 2F7QA 4FZOA 2KHOA 3L3PA 1I4DA 4H8SA 2EFLA 4I1QA 3EJPA 2OP6A 3DX2A 4FZPA 3RV0A 3O3MB 2YL9A 2FYVA 2C08A 1SU8A 3EJSA 4B9QA 4FZSA 2X3WA 4UDYX 3SBTB 4EZXA 3BVWA 1SU6A 4JN4A 3DX1A 4AZBA 3CVRA 2JNSA 1I4LA 4EZOA 2BPRA 3SBSA 2MI7A 2F7PA 3C7NB 4AVMA 2RT6A 2D4CA 5E84A 1E1DA 3QA8A 2F1AA 3CAZA 4NQIA 1Y2OA 3BLBA 1TQUA 4IWOA 1LQ7A 1YWMA 3VEAA 1WDZA 5FLEX 3ABHA 1E2UA 2YKTA 1UPXA 3BVXA 3BUBA 3I04A 2YL6A 2LM0A 3LMFA 2YIVX 2D1LA 4IM2A 4WV5A 1TQWA 2EFKA 4R5IA 3ACOA 3DDGA 5C5BA 3RPMA 3BVTA 3QNIA 2V0OA 3DOBA 1OA1A 4AZ7A 3ER9B 4KIKA 3Q84A 3DPOA 4IM3A 2Q13A 2X3XA 2PMRA 3D4ZA 4KIKB 4F00A 1BPRA 5FIGA 2GAFD 3EJQA 1R34A 1TQSA 3DX0A 3EJUA 2WYIA 4BNEA 1X03A 4JWIA 2RAJA 3ERCC 3D52A 1QWNA 3DPQA 4R5GA 3KAWA 3EJRA 2YL5A 3I01A 3N8EA 4HYBA 4EZSA 3A98A 5KBPA 2Z0VA 4EZTA 2X5CA 1TQTA 3D2EA 2PY6A 3BVUA 3I39X 4DCNC 2RAIA 3T4AG 4EZWA 2OW7A 2YLAA 3C7NA 3F7WA 4AZ5A 4AZHA 3B53X 4R5KA 4IM0A 3D51A 4JLCA 4M0MA 4EZUA 3QWEA 4IWQA 4EZQA 2Z8YA 2ND0A 1URUA 3L3OM 3CKDA 2Z0OA 2V7YA 1HWWA 4R5LA 1GN9A 7HSCA 3VEBA 1GNTA 1O7DB 4PO2A 4EZNA 3RV1A 4HR1B 2YIBA 3DYTA 4AZCB 3FD9A 3T49A 1Q5LA 3M3WA 3O3OB 4ILIA 1R33A 4R5JA 2EWFA 1X04A 1DG4A 2OBLA 4EZRA 2QXLA 1I4TA 3DQGA 4AZIA 4JWEA 2ND1A 1GNLA 2F7RA 2ALWA 4UDXX 3O3NB 3VKHA 3HAHA 3B51X 2YLLA 2X3VA 1E9VA 1CKRA 2RAKA 2YIAA 4NSWA 1HTYA 1HXKA 3DX3A 3DX4A 4ILHB 3B52X 1DKYA 1DKZA 3EJTA 3GI7A 3LLLA 3KAVA 4EZZA 4G6QA 3ZEDA 1O7DC 1DKXA 4WV7A 4ATMA 4JNFA 4IWPA 3LVTA 4F01A 4D8JA 2QFFA 4WPEA 1TQVA 4JL9A 4FM3A 2ZXQA 3HAIA
chains in the Genus database with same CATH topology
4IW0A 4IWOA 3F7WA 1U00A 3B53X 1YUWA 2OBMA 3D2FA 4R5KA 4IM0A 5TKYA 3VEAA 4JLCA 4JWDA 4M0MA 4EZUA 4ILGA 5FLEX 1W9MA 4IWQA 4EZQA 2Z8YA 2ND0A 3OWGA 2EX3B 1E2UA 3H0XA 1UPXA 3L3OM 2V7YA 3I04A 4R5LA 2N3KA 1GN9A 2LM0A 1MJGA 3LMFA 2YIVX 7HSCA 3VEBA 3DPPA 4IM2A 1GNTA 3OHXM 4WV5A 4PO2A 4EZNA 3RV1A 4HR1B 2YIBA 4NPHA 4JWCA 1ZYLA 4R5IA 3FD9A 3T49A 1SUFA 3ZEFA 1OAOA 3O3OB 1Q5LA 2KHOA 4ILIA 1JQKA 2WINM 4R5JA 2EWFA 4H6IA 3KDRA 4H6HA 1DG4A 2OBLA 4EZRA 2YI9A 3DOBA 4HR1A 1OA1A 3QNJA 2OP6A 4HY9A 3UITA 2QXLA 3ER9B 3RV0A 4EZPA 3O3MB 4KIKA 3T47A 3DPOA 4IM3A 3DQGA 4I43A 2GA9D 1SU8A 4B9QA 1OA0A 4JWEA 2ND1A 1GNLA 4UDYX 3SBTB 4KIKB 4F00A 1BPRA 5FIGA 4UDXX 4E81A 4FL9A 3T46A 3O3NB 2GAFD 3VKHA 2NCZA 3B51X 4EZXA 1CKRA 1E9VA 1SU6A 4JN4A 4JNEA 2YIAA 2YI8A 2JNSA 4ILHB 4JWIA 3B52X 1DKYA 3ERCC 4EZOA 1DKZA 2BPRA 3SBSA 3DPQA 3GI7A 4R5GA 3KAWA 3ER8C 3I01A 3KAVA 4EZVA 3N8EA 4HYBA 4EZZA 3C7NB 4EZYA 3T48A 4G6QA 4EZSA 2RT6A 3A98A 3ZEDA 5E84A 1DKXA 4EZTA 2X5CA 4WV7A 3D2EA 2PY6A 4JNFA 3I39X 4IWPA 1E1DA 3QA8A 4F01A 4D8JA 1SU7A 2QFFA 3T4AG 4EZWA 4JL9A 4FM3A 4E3CA 4MQDA 3C7NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EZP A;  4EZN A;  1DKZ A;  3T47 A;  4EZO A;  2BPR A;  3DPQ A;  3DPO A;  1U00 A;  4JWC A;  4R5G A;  4R5I A;  3DQG A;  4EZV A;  1YUW A;  3N8E A;  4HYB A;  3D2F A;  4R5K A;  4JWE A;  4B9Q A;  3T48 A;  5TKY A;  4EZZ A;  4EZY A;  3T49 A;  4EZS A;  4PO2 A;  4JWD A;  1Q5L A;  4EZU A;  5E84 A;  4F00 A;  2KHO A;  1BPR A;  4E81 A;  1DKX A;  3C7N B;  4EZT A;  4FL9 A;  3T46 A;  4EZQ A;  2WIN M;  4WV7 A;  4EZX A;  4R5J A;  3D2E A;  4H6I A;  4JNF A;  1CKR A;  4JN4 A;  4JNE A;  3H0X A;  4H6H A;  1DG4 A;  3L3O M;  4F01 A;  2V7Y A;  4EZR A;  4R5L A;  2QFF A;  3DOB A;  1DKY A;  3T4A G;  4EZW A;  2OP6 A;  3QNJ A;  7HSC A;  4HY9 A;  3DPP A;  4WV5 A;  3OHX M;  4JWI A;  3C7N A;  2QXL A; 
#chains in the Genus database with same CATH topology
 4IW0 A;  3CV5 A;  2O0I 1;  3D4Y A;  3I2W A;  2F18 A;  3CZN A;  2ELB A;  4AKV A;  2JNK A;  2WYH A;  2N3K A;  3BUI A;  2FIC A;  1I49 A;  3BUP A;  4NPH A;  4JWC A;  1ZYL A;  3ZEF A;  3G9G A;  1JQK A;  2WIN M;  4H6I A;  3KDR A;  1QX1 A;  4H6H A;  2YI9 A;  4HR1 A;  3QNJ A;  3Q0K A;  4HY9 A;  2F7O A;  3UIT A;  4AZC A;  4EZP A;  3PLT A;  3T47 A;  2GF4 A;  4I43 A;  2GA9 D;  2LXY A;  1OA0 A;  3QE6 A;  4E81 A;  2YL8 A;  4FL9 A;  3T46 A;  3SOG A;  2NCZ A;  3CZS A;  4JNE A;  2Z0N A;  2QKW A;  2YI8 A;  2OO2 A;  2F1B A;  3ER8 C;  4EZV A;  3BVV A;  4EZY A;  3T48 A;  2OW6 A;  4WPC A;  4AZG A;  2OZN B;  1SU7 A;  4E3C A;  4MQD A;  4DYL A;  1U00 A;  2Q12 A;  1YUW A;  2OBM A;  3D2F A;  5TKY A;  3OK8 A;  4JWD A;  4ILG A;  1ZWW A;  1W9M A;  1R5E A;  3BUQ A;  3OWG A;  2EX3 B;  3D50 A;  3H0X A;  5C5B B;  4AZ6 A;  1PS3 A;  3DDF A;  3HAJ A;  3BUD A;  1MJG A;  3DPP A;  3OHX M;  3SYV A;  1QWU A;  1SUF A;  1OAO A;  2F7Q A;  4FZO A;  2KHO A;  3L3P A;  1I4D A;  4H8S A;  2EFL A;  4I1Q A;  3EJP A;  2OP6 A;  3DX2 A;  4FZP A;  3RV0 A;  3O3M B;  2YL9 A;  2FYV A;  2C08 A;  1SU8 A;  3EJS A;  4B9Q A;  4FZS A;  2X3W A;  4UDY X;  3SBT B;  4EZX A;  3BVW A;  1SU6 A;  4JN4 A;  3DX1 A;  4AZB A;  3CVR A;  2JNS A;  1I4L A;  4EZO A;  2BPR A;  3SBS A;  2MI7 A;  2F7P A;  3C7N B;  4AVM A;  2RT6 A;  2D4C A;  5E84 A;  1E1D A;  3QA8 A;  2F1A A;  3CAZ A;  4NQI A;  1Y2O A;  3BLB A;  1TQU A;  4IWO A;  1LQ7 A;  1YWM A;  3VEA A;  1WDZ A;  5FLE X;  3ABH A;  1E2U A;  2YKT A;  1UPX A;  3BVX A;  3BUB A;  3I04 A;  2YL6 A;  2LM0 A;  3LMF A;  2YIV X;  2D1L A;  4IM2 A;  4WV5 A;  1TQW A;  2EFK A;  4R5I A;  3ACO A;  3DDG A;  5C5B A;  3RPM A;  3BVT A;  3QNI A;  2V0O A;  3DOB A;  1OA1 A;  4AZ7 A;  3ER9 B;  4KIK A;  3Q84 A;  3DPO A;  4IM3 A;  2Q13 A;  2X3X A;  2PMR A;  3D4Z A;  4KIK B;  4F00 A;  1BPR A;  5FIG A;  2GAF D;  3EJQ A;  1R34 A;  1TQS A;  3DX0 A;  3EJU A;  2WYI A;  4BNE A;  1X03 A;  4JWI A;  2RAJ A;  3ERC C;  3D52 A;  1QWN A;  3DPQ A;  4R5G A;  3KAW A;  3EJR A;  2YL5 A;  3I01 A;  3N8E A;  4HYB A;  4EZS A;  3A98 A;  5KBP A;  2Z0V A;  4EZT A;  2X5C A;  1TQT A;  3D2E A;  2PY6 A;  3BVU A;  3I39 X;  4DCN C;  2RAI A;  3T4A G;  4EZW A;  2OW7 A;  2YLA A;  3C7N A;  3F7W A;  4AZ5 A;  4AZH A;  3B53 X;  4R5K A;  4IM0 A;  3D51 A;  4JLC A;  4M0M A;  4EZU A;  3QWE A;  4IWQ A;  4EZQ A;  2Z8Y A;  2ND0 A;  1URU A;  3L3O M;  3CKD A;  2Z0O A;  2V7Y A;  1HWW A;  4R5L A;  1GN9 A;  7HSC A;  3VEB A;  1GNT A;  1O7D B;  4PO2 A;  4EZN A;  3RV1 A;  4HR1 B;  2YIB A;  3DYT A;  4AZC B;  3FD9 A;  3T49 A;  1Q5L A;  3M3W A;  3O3O B;  4ILI A;  1R33 A;  4R5J A;  2EWF A;  1X04 A;  1DG4 A;  2OBL A;  4EZR A;  2QXL A;  1I4T A;  3DQG A;  4AZI A;  4JWE A;  2ND1 A;  1GNL A;  2F7R A;  2ALW A;  4UDX X;  3O3N B;  3VKH A;  3HAH A;  3B51 X;  2YLL A;  2X3V A;  1E9V A;  1CKR A;  2RAK A;  2YIA A;  4NSW A;  1HTY A;  1HXK A;  3DX3 A;  3DX4 A;  4ILH B;  3B52 X;  1DKY A;  1DKZ A;  3EJT A;  3GI7 A;  3LLL A;  3KAV A;  4EZZ A;  4G6Q A;  3ZED A;  1O7D C;  1DKX A;  4WV7 A;  4ATM A;  4JNF A;  4IWP A;  3LVT A;  4F01 A;  4D8J A;  2QFF A;  4WPE A;  1TQV A;  4JL9 A;  4FM3 A;  2ZXQ A;  3HAI A; 
#chains in the Genus database with same CATH homology
 4IW0 A;  4IWO A;  3F7W A;  1U00 A;  3B53 X;  1YUW A;  2OBM A;  3D2F A;  4R5K A;  4IM0 A;  5TKY A;  3VEA A;  4JLC A;  4JWD A;  4M0M A;  4EZU A;  4ILG A;  5FLE X;  1W9M A;  4IWQ A;  4EZQ A;  2Z8Y A;  2ND0 A;  3OWG A;  2EX3 B;  1E2U A;  3H0X A;  1UPX A;  3L3O M;  2V7Y A;  3I04 A;  4R5L A;  2N3K A;  1GN9 A;  2LM0 A;  1MJG A;  3LMF A;  2YIV X;  7HSC A;  3VEB A;  3DPP A;  4IM2 A;  1GNT A;  3OHX M;  4WV5 A;  4PO2 A;  4EZN A;  3RV1 A;  4HR1 B;  2YIB A;  4NPH A;  4JWC A;  1ZYL A;  4R5I A;  3FD9 A;  3T49 A;  1SUF A;  3ZEF A;  1OAO A;  3O3O B;  1Q5L A;  2KHO A;  4ILI A;  1JQK A;  2WIN M;  4R5J A;  2EWF A;  4H6I A;  3KDR A;  4H6H A;  1DG4 A;  2OBL A;  4EZR A;  2YI9 A;  3DOB A;  4HR1 A;  1OA1 A;  3QNJ A;  2OP6 A;  4HY9 A;  3UIT A;  2QXL A;  3ER9 B;  3RV0 A;  4EZP A;  3O3M B;  4KIK A;  3T47 A;  3DPO A;  4IM3 A;  3DQG A;  4I43 A;  2GA9 D;  1SU8 A;  4B9Q A;  1OA0 A;  4JWE A;  2ND1 A;  1GNL A;  4UDY X;  3SBT B;  4KIK B;  4F00 A;  1BPR A;  5FIG A;  4UDX X;  4E81 A;  4FL9 A;  3T46 A;  3O3N B;  2GAF D;  3VKH A;  2NCZ A;  3B51 X;  4EZX A;  1CKR A;  1E9V A;  1SU6 A;  4JN4 A;  4JNE A;  2YIA A;  2YI8 A;  2JNS A;  4ILH B;  4JWI A;  3B52 X;  1DKY A;  3ERC C;  4EZO A;  1DKZ A;  2BPR A;  3SBS A;  3DPQ A;  3GI7 A;  4R5G A;  3KAW A;  3ER8 C;  3I01 A;  3KAV A;  4EZV A;  3N8E A;  4HYB A;  4EZZ A;  3C7N B;  4EZY A;  3T48 A;  4G6Q A;  4EZS A;  2RT6 A;  3A98 A;  3ZED A;  5E84 A;  1DKX A;  4EZT A;  2X5C A;  4WV7 A;  3D2E A;  2PY6 A;  4JNF A;  3I39 X;  4IWP A;  1E1D A;  3QA8 A;  4F01 A;  4D8J A;  1SU7 A;  2QFF A;  3T4A G;  4EZW A;  4JL9 A;  4FM3 A;  4E3C A;  4MQD A;  3C7N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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