4E81A

Crystal structure of the substrate binding domain of e.coli dnak in complex with a short apidaecin peptide
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
214
structure length
214
Chain Sequence
VLLLDVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLMEIA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Api88 is a novel antibacterial designer Peptide to treat systemic infections with multidrug-resistant gram-negative pathogens.
pubmed doi rcsb
molecule tags Chaperone
source organism Escherichia coli
molecule keywords Chaperone protein DnaK
total genus 63
structure length 214
sequence length 214
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-03-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.10 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Substrate Binding Domain Of Dnak; Chain:A; Domain 2 4e81A02
2.60.34.10 Mainly Beta Sandwich Substrate Binding Domain Of DNAk; Chain A, domain 1 Substrate Binding Domain Of DNAk; Chain A, domain 1 4e81A01
4R5LA 4JWCA 1DKXA 3L3OM 4R5JA 4JWEA 4F00A 2WINM 3N8EA 4EZTA 4EZSA 1CKRA 1BPRA 3C7NB 5TKYA 1Q5LA 2QFFA 4EZXA 4EZPA 4PO2A 5E84A 4HY9A 4B9QA 4EZUA 3DQGA 4HYBA 4E81A 3C7NA 3QNJA 4H6HA 7HSCA 4EZRA 2OP6A 3DPQA 3D2FA 4EZQA 4R5IA 3T47A 4H6IA 2V7YA 2KHOA 4JN4A 4EZVA 3DOBA 1U00A 4JWDA 3T46A 3DPOA 3T48A 4EZNA 4F01A 4JNEA 4FL9A 2QXLA 4EZWA 1DKZA 3H0XA 4R5KA 4JNFA 4EZYA 1DG4A 3DPPA 4EZOA 4WV5A 2BPRA 4R5GA 4JWIA 3T49A 4WV7A 3D2EA 3T4AG 4EZZA 1YUWA 3OHXM 1DKYA
chains in the Genus database with same CATH superfamily
2EWFA 3KAVA 1TQTA 2Z8YA 3EJQA 4ILIA 3BUPA 4EZUA 2F1AA 4ILGA 4H6IA 1R5EA 1YWMA 2QXLA 1DKZA 1TQUA 3PLTA 4AZCB 4IW0A 3DDFA 1OA0A 4AZ6A 3CZSA 3D2EA 3Q0KA 4FZPA 1OA1A 3QE6A 2N3KA 2QFFA 2X3WA 3O3MB 3BLBA 7HSCA 4JLCA 1GN9A 4AZIA 3OWGA 3SBSA 4HR1B 3BVVA 2F7QA 2D4CA 3HAIA 4EZTA 4NPHA 2OW6A 2X3XA 5C5BA 3HAJA 2RAKA 2Z0VA 4WPEA 2D1LA 2FYVA 3BVUA 4ILHB 5TKYA 3B51X 3LVTA 4B9QA 2Q13A 2Z0OA 2JNSA 3D50A 2Q12A 2V7YA 2YIBA 3DX3A 2C08A 3B53X 2GAFD 2RT6A 4JWIA 1GNLA 1I4TA 3RPMA 2OW7A 3SYVA 3KDRA 3I39X 4DYLA 1E1DA 3DX4A 4D8JA 3CZNA 3DOBA 2EFKA 3RV0A 4R5KA 2OBMA 4JL9A 4IM3A 3CV5A 1DKXA 3QWEA 4KIKA 2GF4A 3B52X 2ZXQA 3I2WA 3EJTA 3ERCC 4EZQA 3ABHA 2YL5A 2YI9A 1SU8A 3BUQA 3F7WA 2OZNB 2F7RA 4UDXX 4AZ5A 4MQDA 2ELBA 3M3WA 1CKRA 1BPRA 1QWUA 2YKTA 1Q5LA 1W9MA 3EJSA 5E84A 1O7DC 2LXYA 4I1QA 4R5IA 2KHOA 2X3VA 4JWDA 3T46A 1I49A 5KBPA 3H0XA 2EX3B 3I01A 3LLLA 4R5GA 2X5CA 4FM3A 4AZCA 4EZZA 1O7DB 1UPXA 1TQWA 3QA8A 4AZHA 4BNEA 3DQGA 3ER9B 4IWPA 3UITA 1ZYLA 1U00A 2YL6A 4FL9A 4NSWA 4EZYA 2F7OA 3D51A 1PS3A 3ACOA 3FD9A 4IWQA 3T4AG 4HR1A 4M0MA 3DYTA 3CKDA 1SU7A 3BUDA 2YLAA 1OAOA 2JNKA 3SOGA 3DX2A 3T48A 4F01A 2EFLA 2YL9A 3DPPA 5FLEX 3BVWA 1YUWA 3EJRA 1WDZA 3VEBA 1TQVA 1E2UA 1TQSA 3I04A 4AZGA 3C7NB 1SU6A 4PO2A 1QWNA 4HYBA 3RV1A 4H6HA 4EZRA 2OBLA 3GI7A 3D2FA 3DPQA 4E3CA 1I4DA 2ND0A 3G9GA 4AZBA 3SBTB 4JNFA 1QX1A 3CVRA 3HAHA 4WV7A 2V0OA 4H8SA 3L3PA 1MJGA 4F00A 3VKHA 2QKWA 2MI7A 3D4YA 2F18A 4IWOA 1SUFA 4EZVA 2RAIA 1JQKA 3D52A 3ZEFA 3OK8A 2ALWA 2F7PA 4JWEA 4UDYX 4EZSA 1X04A 4EZPA 3CAZA 2YIVX 3T47A 2YI8A 2LM0A 4JN4A 2PY6A 3QNIA 1DG4A 3Q84A 3D4ZA 4JWCA 3N8EA 4FZOA 1HXKA 2WINM 3VEAA 5C5BB 4IM0A 1E9VA 4EZXA 1X03A 2FICA 3ZEDA 2Z0NA 3DX0A 3EJPA 3EJUA 4ATMA 3DDGA 4WV5A 2BPRA 4AVMA 2NCZA 3LMFA 4AKVA 3L3OM 1HWWA 1I4LA 2ND1A 3ER8C 4NQIA 1R34A 4I43A 2RAJA 1HTYA 4WPCA 2OP6A 3BUIA 4G6QA 4EZOA 4AZ7A 3DX1A 3OHXM 4R5JA 3BVXA 2WYIA 3QNJA 2WYHA 1LQ7A 2GA9D 3BUBA 3DPOA 1R33A 4DCNC 4EZWA 2YL8A 3A98A 3O3OB 4KIKB 3O3NB 4HY9A 1URUA 4R5LA 4FZSA 2YLLA 2F1BA 3BVTA 4E81A 3C7NA 2YIAA 1Y2OA 4EZNA 3KAWA 4JNEA 5FIGA 1ZWWA 1GNTA 4IM2A 2O0I1 3T49A 2PMRA 2OO2A 1DKYA
chains in the Genus database with same CATH topology
4M0MA 2EWFA 1GNLA 2WINM 3VEAA 3KAVA 2Z8YA 4IM0A 1SU7A 1E9VA 4EZXA 3KDRA 3I39X 4ILIA 4EZUA 3ZEDA 1OAOA 1E1DA 4ILGA 4H6IA 4D8JA 3DOBA 3T48A 4F01A 2QXLA 1DKZA 3RV0A 4R5KA 2OBMA 3DPPA 4WV5A 5FLEX 2BPRA 4IW0A 1OA0A 3D2EA 2NCZA 3LMFA 1YUWA 4JL9A 4IM3A 1OA1A 1DKXA 3L3OM 3VEBA 4KIKA 1E2UA 2ND1A 3I04A 3ER8C 3B52X 2N3KA 3C7NB 1SU6A 2QFFA 4PO2A 3O3MB 4I43A 4HYBA 7HSCA 3RV1A 4H6HA 3ERCC 4EZRA 2OBLA 3GI7A 3D2FA 3DPQA 4JLCA 4EZQA 2OP6A 1GN9A 4E3CA 2ND0A 2YI9A 4G6QA 3OWGA 1SU8A 3F7WA 3SBTB 4JNFA 4EZOA 3SBSA 4HR1B 4UDXX 4WV7A 3OHXM 4MQDA 4R5JA 1MJGA 4F00A 3VKHA 4EZTA 1CKRA 4NPHA 1BPRA 1Q5LA 1W9MA 5E84A 3QNJA 4R5IA 2KHOA 4IWOA 1SUFA 2GA9D 4EZVA 4JWDA 1JQKA 3DPOA 3T46A 4EZWA 3H0XA 2EX3B 3I01A 3ZEFA 3A98A 4R5GA 3O3OB 4KIKB 2X5CA 4FM3A 3O3NB 4EZZA 4HY9A 4R5LA 4JWEA 1UPXA 3QA8A 4UDYX 4EZSA 4ILHB 5TKYA 3B51X 4EZPA 4B9QA 3DQGA 4E81A 3C7NA 3ER9B 2JNSA 2YIVX 3T47A 4IWPA 3UITA 2YI8A 2YIAA 2V7YA 2LM0A 2YIBA 1ZYLA 4JN4A 1U00A 4EZNA 2PY6A 3KAWA 4FL9A 4JNEA 1DG4A 3B53X 4EZYA 2GAFD 5FIGA 2RT6A 1GNTA 4IM2A 4JWIA 3T49A 3FD9A 4IWQA 4JWCA 3T4AG 3N8EA 4HR1A 1DKYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4R5L A;  4JWC A;  1DKX A;  3L3O M;  4R5J A;  4JWE A;  4F00 A;  2WIN M;  3N8E A;  4EZT A;  4EZS A;  1CKR A;  1BPR A;  3C7N B;  5TKY A;  1Q5L A;  2QFF A;  4EZX A;  4EZP A;  4PO2 A;  5E84 A;  4HY9 A;  4B9Q A;  4EZU A;  3DQG A;  4HYB A;  4E81 A;  3C7N A;  3QNJ A;  4H6H A;  7HSC A;  4EZR A;  2OP6 A;  3DPQ A;  3D2F A;  4EZQ A;  4R5I A;  3T47 A;  4H6I A;  2V7Y A;  2KHO A;  4JN4 A;  4EZV A;  3DOB A;  1U00 A;  4JWD A;  3T46 A;  3DPO A;  3T48 A;  4EZN A;  4F01 A;  4JNE A;  4FL9 A;  2QXL A;  4EZW A;  1DKZ A;  3H0X A;  4R5K A;  4JNF A;  4EZY A;  1DG4 A;  3DPP A;  4EZO A;  4WV5 A;  2BPR A;  4R5G A;  4JWI A;  3T49 A;  4WV7 A;  3D2E A;  3T4A G;  4EZZ A;  1YUW A;  3OHX M;  1DKY A; 
#chains in the Genus database with same CATH topology
 2EWF A;  3KAV A;  1TQT A;  2Z8Y A;  3EJQ A;  4ILI A;  3BUP A;  4EZU A;  2F1A A;  4ILG A;  4H6I A;  1R5E A;  1YWM A;  2QXL A;  1DKZ A;  1TQU A;  3PLT A;  4AZC B;  4IW0 A;  3DDF A;  1OA0 A;  4AZ6 A;  3CZS A;  3D2E A;  3Q0K A;  4FZP A;  1OA1 A;  3QE6 A;  2N3K A;  2QFF A;  2X3W A;  3O3M B;  3BLB A;  7HSC A;  4JLC A;  1GN9 A;  4AZI A;  3OWG A;  3SBS A;  4HR1 B;  3BVV A;  2F7Q A;  2D4C A;  3HAI A;  4EZT A;  4NPH A;  2OW6 A;  2X3X A;  5C5B A;  3HAJ A;  2RAK A;  2Z0V A;  4WPE A;  2D1L A;  2FYV A;  3BVU A;  4ILH B;  5TKY A;  3B51 X;  3LVT A;  4B9Q A;  2Q13 A;  2Z0O A;  2JNS A;  3D50 A;  2Q12 A;  2V7Y A;  2YIB A;  3DX3 A;  2C08 A;  3B53 X;  2GAF D;  2RT6 A;  4JWI A;  1GNL A;  1I4T A;  3RPM A;  2OW7 A;  3SYV A;  3KDR A;  3I39 X;  4DYL A;  1E1D A;  3DX4 A;  4D8J A;  3CZN A;  3DOB A;  2EFK A;  3RV0 A;  4R5K A;  2OBM A;  4JL9 A;  4IM3 A;  3CV5 A;  1DKX A;  3QWE A;  4KIK A;  2GF4 A;  3B52 X;  2ZXQ A;  3I2W A;  3EJT A;  3ERC C;  4EZQ A;  3ABH A;  2YL5 A;  2YI9 A;  1SU8 A;  3BUQ A;  3F7W A;  2OZN B;  2F7R A;  4UDX X;  4AZ5 A;  4MQD A;  2ELB A;  3M3W A;  1CKR A;  1BPR A;  1QWU A;  2YKT A;  1Q5L A;  1W9M A;  3EJS A;  5E84 A;  1O7D C;  2LXY A;  4I1Q A;  4R5I A;  2KHO A;  2X3V A;  4JWD A;  3T46 A;  1I49 A;  5KBP A;  3H0X A;  2EX3 B;  3I01 A;  3LLL A;  4R5G A;  2X5C A;  4FM3 A;  4AZC A;  4EZZ A;  1O7D B;  1UPX A;  1TQW A;  3QA8 A;  4AZH A;  4BNE A;  3DQG A;  3ER9 B;  4IWP A;  3UIT A;  1ZYL A;  1U00 A;  2YL6 A;  4FL9 A;  4NSW A;  4EZY A;  2F7O A;  3D51 A;  1PS3 A;  3ACO A;  3FD9 A;  4IWQ A;  3T4A G;  4HR1 A;  4M0M A;  3DYT A;  3CKD A;  1SU7 A;  3BUD A;  2YLA A;  1OAO A;  2JNK A;  3SOG A;  3DX2 A;  3T48 A;  4F01 A;  2EFL A;  2YL9 A;  3DPP A;  5FLE X;  3BVW A;  1YUW A;  3EJR A;  1WDZ A;  3VEB A;  1TQV A;  1E2U A;  1TQS A;  3I04 A;  4AZG A;  3C7N B;  1SU6 A;  4PO2 A;  1QWN A;  4HYB A;  3RV1 A;  4H6H A;  4EZR A;  2OBL A;  3GI7 A;  3D2F A;  3DPQ A;  4E3C A;  1I4D A;  2ND0 A;  3G9G A;  4AZB A;  3SBT B;  4JNF A;  1QX1 A;  3CVR A;  3HAH A;  4WV7 A;  2V0O A;  4H8S A;  3L3P A;  1MJG A;  4F00 A;  3VKH A;  2QKW A;  2MI7 A;  3D4Y A;  2F18 A;  4IWO A;  1SUF A;  4EZV A;  2RAI A;  1JQK A;  3D52 A;  3ZEF A;  3OK8 A;  2ALW A;  2F7P A;  4JWE A;  4UDY X;  4EZS A;  1X04 A;  4EZP A;  3CAZ A;  2YIV X;  3T47 A;  2YI8 A;  2LM0 A;  4JN4 A;  2PY6 A;  3QNI A;  1DG4 A;  3Q84 A;  3D4Z A;  4JWC A;  3N8E A;  4FZO A;  1HXK A;  2WIN M;  3VEA A;  5C5B B;  4IM0 A;  1E9V A;  4EZX A;  1X03 A;  2FIC A;  3ZED A;  2Z0N A;  3DX0 A;  3EJP A;  3EJU A;  4ATM A;  3DDG A;  4WV5 A;  2BPR A;  4AVM A;  2NCZ A;  3LMF A;  4AKV A;  3L3O M;  1HWW A;  1I4L A;  2ND1 A;  3ER8 C;  4NQI A;  1R34 A;  4I43 A;  2RAJ A;  1HTY A;  4WPC A;  2OP6 A;  3BUI A;  4G6Q A;  4EZO A;  4AZ7 A;  3DX1 A;  3OHX M;  4R5J A;  3BVX A;  2WYI A;  3QNJ A;  2WYH A;  1LQ7 A;  2GA9 D;  3BUB A;  3DPO A;  1R33 A;  4DCN C;  4EZW A;  2YL8 A;  3A98 A;  3O3O B;  4KIK B;  3O3N B;  4HY9 A;  1URU A;  4R5L A;  4FZS A;  2YLL A;  2F1B A;  3BVT A;  4E81 A;  3C7N A;  2YIA A;  1Y2O A;  4EZN A;  3KAW A;  4JNE A;  5FIG A;  1ZWW A;  1GNT A;  4IM2 A;  2O0I 1;  3T49 A;  2PMR A;  2OO2 A;  1DKY A; 
#chains in the Genus database with same CATH homology
 4M0M A;  2EWF A;  1GNL A;  2WIN M;  3VEA A;  3KAV A;  2Z8Y A;  4IM0 A;  1SU7 A;  1E9V A;  4EZX A;  3KDR A;  3I39 X;  4ILI A;  4EZU A;  3ZED A;  1OAO A;  1E1D A;  4ILG A;  4H6I A;  4D8J A;  3DOB A;  3T48 A;  4F01 A;  2QXL A;  1DKZ A;  3RV0 A;  4R5K A;  2OBM A;  3DPP A;  4WV5 A;  5FLE X;  2BPR A;  4IW0 A;  1OA0 A;  3D2E A;  2NCZ A;  3LMF A;  1YUW A;  4JL9 A;  4IM3 A;  1OA1 A;  1DKX A;  3L3O M;  3VEB A;  4KIK A;  1E2U A;  2ND1 A;  3I04 A;  3ER8 C;  3B52 X;  2N3K A;  3C7N B;  1SU6 A;  2QFF A;  4PO2 A;  3O3M B;  4I43 A;  4HYB A;  7HSC A;  3RV1 A;  4H6H A;  3ERC C;  4EZR A;  2OBL A;  3GI7 A;  3D2F A;  3DPQ A;  4JLC A;  4EZQ A;  2OP6 A;  1GN9 A;  4E3C A;  2ND0 A;  2YI9 A;  4G6Q A;  3OWG A;  1SU8 A;  3F7W A;  3SBT B;  4JNF A;  4EZO A;  3SBS A;  4HR1 B;  4UDX X;  4WV7 A;  3OHX M;  4MQD A;  4R5J A;  1MJG A;  4F00 A;  3VKH A;  4EZT A;  1CKR A;  4NPH A;  1BPR A;  1Q5L A;  1W9M A;  5E84 A;  3QNJ A;  4R5I A;  2KHO A;  4IWO A;  1SUF A;  2GA9 D;  4EZV A;  4JWD A;  1JQK A;  3DPO A;  3T46 A;  4EZW A;  3H0X A;  2EX3 B;  3I01 A;  3ZEF A;  3A98 A;  4R5G A;  3O3O B;  4KIK B;  2X5C A;  4FM3 A;  3O3N B;  4EZZ A;  4HY9 A;  4R5L A;  4JWE A;  1UPX A;  3QA8 A;  4UDY X;  4EZS A;  4ILH B;  5TKY A;  3B51 X;  4EZP A;  4B9Q A;  3DQG A;  4E81 A;  3C7N A;  3ER9 B;  2JNS A;  2YIV X;  3T47 A;  4IWP A;  3UIT A;  2YI8 A;  2YIA A;  2V7Y A;  2LM0 A;  2YIB A;  1ZYL A;  4JN4 A;  1U00 A;  4EZN A;  2PY6 A;  3KAW A;  4FL9 A;  4JNE A;  1DG4 A;  3B53 X;  4EZY A;  2GAF D;  5FIG A;  2RT6 A;  1GNT A;  4IM2 A;  4JWI A;  3T49 A;  3FD9 A;  4IWQ A;  4JWC A;  3T4A G;  3N8E A;  4HR1 A;  1DKY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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