4JNFA

Allosteric opening of the polypeptide-binding site when an hsp70 binds atp
Total Genus 64
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
213
structure length
213
Chain Sequence
SVLLLDVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSMGGAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP.
pubmed doi rcsb
molecule tags Chaperone
source organism Escherichia coli
molecule keywords Hsp70 CHAPERONE DnaK
total genus 64
structure length 213
sequence length 213
ec nomenclature
pdb deposition date 2013-03-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.10 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Substrate Binding Domain Of Dnak; Chain:A; Domain 2 4jnfA02
2.60.34.10 Mainly Beta Sandwich Substrate Binding Domain Of DNAk; Chain A, domain 1 Substrate Binding Domain Of DNAk; Chain A, domain 1 4jnfA01
4WV5A 4R5LA 4EZOA 3DPPA 1DKZA 4EZRA 1BPRA 3DQGA 1U00A 1Q5LA 4EZPA 4PO2A 1DKXA 4HYBA 4EZQA 1CKRA 3N8EA 3DPQA 4EZNA 4EZTA 7HSCA 4H6HA 4JWIA 4JN4A 3L3OM 4JNEA 4FL9A 3T49A 4E81A 4H6IA 2WINM 4JWCA 4EZUA 4F01A 3T47A 2V7YA 3OHXM 3C7NA 4EZYA 2QXLA 4HY9A 4R5GA 4EZZA 1DKYA 4JNFA 3D2FA 2OP6A 4JWEA 3C7NB 1YUWA 3T48A 3QNJA 3H0XA 4JWDA 4EZVA 4R5KA 4R5JA 3DOBA 4B9QA 3T4AG 4WV7A 5TKYA 4F00A 3D2EA 4EZWA 4EZSA 4EZXA 2QFFA 2BPRA 2KHOA 4R5IA 3T46A 1DG4A 5E84A 3DPOA
chains in the Genus database with same CATH superfamily
3DPPA 3D4YA 4EZRA 4IWPA 3HAHA 1GN9A 3ZEDA 1WDZA 1DKXA 4EZQA 1W9MA 3N8EA 3KAWA 3BVTA 3BUDA 2MI7A 4H6IA 3SYVA 4HY9A 1I4LA 3VEAA 2OP6A 3T48A 3BVXA 2QFFA 2BPRA 2WYHA 4EZOA 3BVWA 4FZSA 4UDYX 2OBLA 4E81A 2D1LA 3ER9B 4EZZA 3C7NB 4JNFA 3DOBA 3SOGA 2LM0A 3CZNA 3L3PA 4KIKB 2FICA 4DCNC 3KDRA 3OHXM 2F1BA 3KAVA 4NSWA 2EX3B 3VKHA 3D52A 2YIVX 2KHOA 3T46A 3PLTA 3EJPA 4WV5A 1URUA 3EJSA 1MJGA 2F7OA 4UDXX 3ERCC 1TQUA 3GI7A 3RPMA 3T47A 1SU7A 2RT6A 3M3WA 3D50A 4BNEA 3O3MB 4EZVA 1GNTA 4R5JA 4ATMA 3SBTB 2EFLA 2GAFD 1R5EA 4JN4A 1OAOA 1SU8A 2F18A 3T4AG 3EJTA 3I04A 4WPEA 2RAKA 2PY6A 3O3NB 1BPRA 2F1AA 4IW0A 3QWEA 1R33A 4H6HA 3QA8A 1SU6A 2PMRA 3VEBA 4F01A 5FIGA 1TQWA 3CZSA 2F7RA 4DYLA 4JWDA 1UPXA 3HAIA 2GF4A 1JQKA 4AVMA 3EJUA 2X3WA 1QX1A 4PO2A 4HYBA 1HXKA 4D8JA 3CAZA 4EZUA 2EFKA 4JWEA 3EJRA 2Z0NA 4IM0A 2GA9D 1E1DA 3LLLA 4EZWA 4MQDA 3DX4A 2YL5A 3DPOA 5E84A 4NPHA 2YL9A 3DQGA 1U00A 2JNSA 4EZPA 1QWNA 4AZ6A 4FL9A 1E2UA 2LXYA 2YLLA 5FLEX 1DKYA 4AZCA 2RAIA 4AZCB 1O7DC 2X3XA 3DX0A 4B9QA 1OA0A 1LQ7A 4EZSA 4EZXA 3UITA 2O0I1 3CVRA 3OWGA 1DKZA 2F7QA 3RV1A 1X03A 4M0MA 4I1QA 2RAJA 4G6QA 4R5KA 2ZXQA 2YL8A 4ILGA 1ZWWA 2V0OA 3DX1A 3B53X 3OK8A 2ND1A 3Q84A 3BUBA 1Y2OA 4AKVA 1E9VA 1GNLA 2NCZA 4FZOA 2YIBA 2Q13A 3ACOA 2N3KA 2WINM 2YKTA 1OA1A 2V7YA 3B52X 4AZHA 3SBSA 2FYVA 2X3VA 1YWMA 4E3CA 1TQTA 3B51X 5C5BA 4JL9A 3LMFA 3HAJA 3CKDA 1SUFA 4EZNA 4JLCA 3QNIA 3I01A 4JWCA 4AZIA 1O7DB 3BVVA 3D51A 3QNJA 7HSCA 2WYIA 5TKYA 4I43A 4R5LA 4IM3A 2ALWA 2QKWA 4IWQA 3ZEFA 4EZTA 4JNEA 4AZGA 2QXLA 2OBMA 2JNKA 3BLBA 2YI8A 3DX2A 2Q12A 3I39X 2YL6A 3CV5A 3DYTA 3DX3A 1CKRA 4IWOA 2X5CA 1I4DA 1ZYLA 3L3OM 4WPCA 3QE6A 3C7NA 3G9GA 3D2FA 3EJQA 3O3OB 1DG4A 1HTYA 4AZ7A 4FM3A 4ILHB 1HWWA 3LVTA 1PS3A 4IM2A 4KIKA 3FD9A 4JWIA 3T49A 2YI9A 4R5GA 2F7PA 4AZBA 1R34A 3DDGA 3D2EA 3D4ZA 4F00A 3F7WA 1X04A 4EZYA 2EWFA 4R5IA 1TQSA 2OO2A 1Q5LA 3A98A 2YLAA 4FZPA 2ELBA 4HR1A 4HR1B 2D4CA 3BUPA 2Z0VA 1I4TA 2ND0A 2OW6A 2C08A 2OZNB 3Q0KA 4WV7A 3BUQA 5KBPA 1QWUA 2Z8YA 3I2WA 4H8SA 3ABHA 3DDFA 2YIAA 1I49A 3BVUA 1TQVA 3RV0A 2OW7A 5C5BB 3DPQA 3BUIA 3ER8C 4ILIA 3H0XA 1YUWA 4AZ5A 2Z0OA 4NQIA
chains in the Genus database with same CATH topology
3DPPA 1DKZA 3I39X 3OWGA 4EZRA 4IWPA 3RV1A 1GN9A 3ZEDA 2GAFD 4M0MA 1DKXA 4EZQA 1CKRA 4IWOA 1W9MA 2X5CA 3KAWA 3N8EA 4JN4A 1ZYLA 3L3OM 1OAOA 4H6IA 3C7NA 4HY9A 1SU8A 3VEAA 3D2FA 2OP6A 4G6QA 3T48A 4R5KA 3T4AG 3O3OB 3I04A 4ILGA 2QFFA 2BPRA 1DG4A 2PY6A 3B53X 4EZOA 2ND1A 3O3NB 1BPRA 4FM3A 4ILHB 1E9VA 4IW0A 1GNLA 2NCZA 4KIKA 2YIBA 4IM2A 4UDYX 3FD9A 2OBLA 4H6HA 3QA8A 4JWIA 1SU6A 3VEBA 2N3KA 3T49A 2YI9A 4E81A 2WINM 4F01A 1OA1A 5FIGA 2V7YA 4R5GA 3ER9B 4EZZA 3C7NB 4JNFA 3B52X 4JWDA 1UPXA 3DOBA 3SBSA 2LM0A 4F00A 3D2EA 3F7WA 1JQKA 4EZYA 2EWFA 4R5IA 4E3CA 3B51X 4JL9A 1Q5LA 3A98A 3LMFA 4PO2A 4HYBA 4D8JA 1SUFA 4KIKB 4EZNA 4JLCA 4HR1A 4HR1B 3I01A 3KDRA 4JWCA 4EZUA 3OHXM 2ND0A 3KAVA 4JWEA 3QNJA 7HSCA 4WV7A 4IM0A 2GA9D 2EX3B 1E1DA 5TKYA 3VKHA 4EZWA 2YIVX 4MQDA 4I43A 2Z8YA 2KHOA 3T46A 5E84A 3DPOA 4WV5A 4R5LA 2YIAA 4NPHA 4IM3A 3RV0A 3DQGA 1U00A 2JNSA 4EZPA 4IWQA 1MJGA 4UDXX 3ERCC 3ZEFA 3DPQA 4EZTA 4JNEA 3GI7A 3ER8C 4FL9A 1E2UA 5FLEX 3T47A 1SU7A 2RT6A 2QXLA 2OBMA 4ILIA 1DKYA 3H0XA 3O3MB 1YUWA 4EZVA 1GNTA 4R5JA 4B9QA 1OA0A 3SBTB 2YI8A 4EZSA 4EZXA 3UITA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WV5 A;  4R5L A;  4EZO A;  3DPP A;  1DKZ A;  4EZR A;  1BPR A;  3DQG A;  1U00 A;  1Q5L A;  4EZP A;  4PO2 A;  1DKX A;  4HYB A;  4EZQ A;  1CKR A;  3N8E A;  3DPQ A;  4EZN A;  4EZT A;  7HSC A;  4H6H A;  4JWI A;  4JN4 A;  3L3O M;  4JNE A;  4FL9 A;  3T49 A;  4E81 A;  4H6I A;  2WIN M;  4JWC A;  4EZU A;  4F01 A;  3T47 A;  2V7Y A;  3OHX M;  3C7N A;  4EZY A;  2QXL A;  4HY9 A;  4R5G A;  4EZZ A;  1DKY A;  4JNF A;  3D2F A;  2OP6 A;  4JWE A;  3C7N B;  1YUW A;  3T48 A;  3QNJ A;  3H0X A;  4JWD A;  4EZV A;  4R5K A;  4R5J A;  3DOB A;  4B9Q A;  3T4A G;  4WV7 A;  5TKY A;  4F00 A;  3D2E A;  4EZW A;  4EZS A;  4EZX A;  2QFF A;  2BPR A;  2KHO A;  4R5I A;  3T46 A;  1DG4 A;  5E84 A;  3DPO A; 
#chains in the Genus database with same CATH topology
 3DPP A;  3D4Y A;  4EZR A;  4IWP A;  3HAH A;  1GN9 A;  3ZED A;  1WDZ A;  1DKX A;  4EZQ A;  1W9M A;  3N8E A;  3KAW A;  3BVT A;  3BUD A;  2MI7 A;  4H6I A;  3SYV A;  4HY9 A;  1I4L A;  3VEA A;  2OP6 A;  3T48 A;  3BVX A;  2QFF A;  2BPR A;  2WYH A;  4EZO A;  3BVW A;  4FZS A;  4UDY X;  2OBL A;  4E81 A;  2D1L A;  3ER9 B;  4EZZ A;  3C7N B;  4JNF A;  3DOB A;  3SOG A;  2LM0 A;  3CZN A;  3L3P A;  4KIK B;  2FIC A;  4DCN C;  3KDR A;  3OHX M;  2F1B A;  3KAV A;  4NSW A;  2EX3 B;  3VKH A;  3D52 A;  2YIV X;  2KHO A;  3T46 A;  3PLT A;  3EJP A;  4WV5 A;  1URU A;  3EJS A;  1MJG A;  2F7O A;  4UDX X;  3ERC C;  1TQU A;  3GI7 A;  3RPM A;  3T47 A;  1SU7 A;  2RT6 A;  3M3W A;  3D50 A;  4BNE A;  3O3M B;  4EZV A;  1GNT A;  4R5J A;  4ATM A;  3SBT B;  2EFL A;  2GAF D;  1R5E A;  4JN4 A;  1OAO A;  1SU8 A;  2F18 A;  3T4A G;  3EJT A;  3I04 A;  4WPE A;  2RAK A;  2PY6 A;  3O3N B;  1BPR A;  2F1A A;  4IW0 A;  3QWE A;  1R33 A;  4H6H A;  3QA8 A;  1SU6 A;  2PMR A;  3VEB A;  4F01 A;  5FIG A;  1TQW A;  3CZS A;  2F7R A;  4DYL A;  4JWD A;  1UPX A;  3HAI A;  2GF4 A;  1JQK A;  4AVM A;  3EJU A;  2X3W A;  1QX1 A;  4PO2 A;  4HYB A;  1HXK A;  4D8J A;  3CAZ A;  4EZU A;  2EFK A;  4JWE A;  3EJR A;  2Z0N A;  4IM0 A;  2GA9 D;  1E1D A;  3LLL A;  4EZW A;  4MQD A;  3DX4 A;  2YL5 A;  3DPO A;  5E84 A;  4NPH A;  2YL9 A;  3DQG A;  1U00 A;  2JNS A;  4EZP A;  1QWN A;  4AZ6 A;  4FL9 A;  1E2U A;  2LXY A;  2YLL A;  5FLE X;  1DKY A;  4AZC A;  2RAI A;  4AZC B;  1O7D C;  2X3X A;  3DX0 A;  4B9Q A;  1OA0 A;  1LQ7 A;  4EZS A;  4EZX A;  3UIT A;  2O0I 1;  3CVR A;  3OWG A;  1DKZ A;  2F7Q A;  3RV1 A;  1X03 A;  4M0M A;  4I1Q A;  2RAJ A;  4G6Q A;  4R5K A;  2ZXQ A;  2YL8 A;  4ILG A;  1ZWW A;  2V0O A;  3DX1 A;  3B53 X;  3OK8 A;  2ND1 A;  3Q84 A;  3BUB A;  1Y2O A;  4AKV A;  1E9V A;  1GNL A;  2NCZ A;  4FZO A;  2YIB A;  2Q13 A;  3ACO A;  2N3K A;  2WIN M;  2YKT A;  1OA1 A;  2V7Y A;  3B52 X;  4AZH A;  3SBS A;  2FYV A;  2X3V A;  1YWM A;  4E3C A;  1TQT A;  3B51 X;  5C5B A;  4JL9 A;  3LMF A;  3HAJ A;  3CKD A;  1SUF A;  4EZN A;  4JLC A;  3QNI A;  3I01 A;  4JWC A;  4AZI A;  1O7D B;  3BVV A;  3D51 A;  3QNJ A;  7HSC A;  2WYI A;  5TKY A;  4I43 A;  4R5L A;  4IM3 A;  2ALW A;  2QKW A;  4IWQ A;  3ZEF A;  4EZT A;  4JNE A;  4AZG A;  2QXL A;  2OBM A;  2JNK A;  3BLB A;  2YI8 A;  3DX2 A;  2Q12 A;  3I39 X;  2YL6 A;  3CV5 A;  3DYT A;  3DX3 A;  1CKR A;  4IWO A;  2X5C A;  1I4D A;  1ZYL A;  3L3O M;  4WPC A;  3QE6 A;  3C7N A;  3G9G A;  3D2F A;  3EJQ A;  3O3O B;  1DG4 A;  1HTY A;  4AZ7 A;  4FM3 A;  4ILH B;  1HWW A;  3LVT A;  1PS3 A;  4IM2 A;  4KIK A;  3FD9 A;  4JWI A;  3T49 A;  2YI9 A;  4R5G A;  2F7P A;  4AZB A;  1R34 A;  3DDG A;  3D2E A;  3D4Z A;  4F00 A;  3F7W A;  1X04 A;  4EZY A;  2EWF A;  4R5I A;  1TQS A;  2OO2 A;  1Q5L A;  3A98 A;  2YLA A;  4FZP A;  2ELB A;  4HR1 A;  4HR1 B;  2D4C A;  3BUP A;  2Z0V A;  1I4T A;  2ND0 A;  2OW6 A;  2C08 A;  2OZN B;  3Q0K A;  4WV7 A;  3BUQ A;  5KBP A;  1QWU A;  2Z8Y A;  3I2W A;  4H8S A;  3ABH A;  3DDF A;  2YIA A;  1I49 A;  3BVU A;  1TQV A;  3RV0 A;  2OW7 A;  5C5B B;  3DPQ A;  3BUI A;  3ER8 C;  4ILI A;  3H0X A;  1YUW A;  4AZ5 A;  2Z0O A;  4NQI A; 
#chains in the Genus database with same CATH homology
 3DPP A;  1DKZ A;  3I39 X;  3OWG A;  4EZR A;  4IWP A;  3RV1 A;  1GN9 A;  3ZED A;  2GAF D;  4M0M A;  1DKX A;  4EZQ A;  1CKR A;  4IWO A;  1W9M A;  2X5C A;  3KAW A;  3N8E A;  4JN4 A;  1ZYL A;  3L3O M;  1OAO A;  4H6I A;  3C7N A;  4HY9 A;  1SU8 A;  3VEA A;  3D2F A;  2OP6 A;  4G6Q A;  3T48 A;  4R5K A;  3T4A G;  3O3O B;  3I04 A;  4ILG A;  2QFF A;  2BPR A;  1DG4 A;  2PY6 A;  3B53 X;  4EZO A;  2ND1 A;  3O3N B;  1BPR A;  4FM3 A;  4ILH B;  1E9V A;  4IW0 A;  1GNL A;  2NCZ A;  4KIK A;  2YIB A;  4IM2 A;  4UDY X;  3FD9 A;  2OBL A;  4H6H A;  3QA8 A;  4JWI A;  1SU6 A;  3VEB A;  2N3K A;  3T49 A;  2YI9 A;  4E81 A;  2WIN M;  4F01 A;  1OA1 A;  5FIG A;  2V7Y A;  4R5G A;  3ER9 B;  4EZZ A;  3C7N B;  4JNF A;  3B52 X;  4JWD A;  1UPX A;  3DOB A;  3SBS A;  2LM0 A;  4F00 A;  3D2E A;  3F7W A;  1JQK A;  4EZY A;  2EWF A;  4R5I A;  4E3C A;  3B51 X;  4JL9 A;  1Q5L A;  3A98 A;  3LMF A;  4PO2 A;  4HYB A;  4D8J A;  1SUF A;  4KIK B;  4EZN A;  4JLC A;  4HR1 A;  4HR1 B;  3I01 A;  3KDR A;  4JWC A;  4EZU A;  3OHX M;  2ND0 A;  3KAV A;  4JWE A;  3QNJ A;  7HSC A;  4WV7 A;  4IM0 A;  2GA9 D;  2EX3 B;  1E1D A;  5TKY A;  3VKH A;  4EZW A;  2YIV X;  4MQD A;  4I43 A;  2Z8Y A;  2KHO A;  3T46 A;  5E84 A;  3DPO A;  4WV5 A;  4R5L A;  2YIA A;  4NPH A;  4IM3 A;  3RV0 A;  3DQG A;  1U00 A;  2JNS A;  4EZP A;  4IWQ A;  1MJG A;  4UDX X;  3ERC C;  3ZEF A;  3DPQ A;  4EZT A;  4JNE A;  3GI7 A;  3ER8 C;  4FL9 A;  1E2U A;  5FLE X;  3T47 A;  1SU7 A;  2RT6 A;  2QXL A;  2OBM A;  4ILI A;  1DKY A;  3H0X A;  3O3M B;  1YUW A;  4EZV A;  1GNT A;  4R5J A;  4B9Q A;  1OA0 A;  3SBT B;  2YI8 A;  4EZS A;  4EZX A;  3UIT A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...