3BACA

Structural basis for the inhibition of bacterial nad+ dependent dna ligase
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
255
structure length
255
Chain Sequence
GFSQIRHEIPMLSLDNAFSDAEFNAFVKRIEDRLILLPKPLTFCCEPKLDGLAVSILYVNGELTQAATRGDGTTGEDITANIRTIRNVPLQLLTDNPPARLEVRGEVFMPHAGFERLNKYALEHNEKTFANPRNAAAGSLRQLDPNITSKRPLVLNAYGIGIAEGVGLPTTHYARLQWLKSIGIPVNPEIRLCNGADEVLDFYQDIQNKRSSLGYDIDGTVLKINDIALQNELGFISKAPRWAIAYKFPAQEELT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for the Inhibition of Bacterial NAD+ Dependent DNA Ligase
rcsb
molecule tags Ligase
source organism Haemophilus influenzae
molecule keywords DNA ligase
total genus 67
structure length 255
sequence length 255
ec nomenclature ec 6.5.1.2: DNA ligase (NAD(+)).
pdb deposition date 2007-11-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.470.90 Alpha Beta 2-Layer Sandwich D-amino Acid Aminotransferase; Chain A, domain 1 D-amino Acid Aminotransferase; Chain A, domain 1 3bacA01
3SGIA 4GLWA 1ZAUA 3BACA
chains in the Genus database with same CATH superfamily
2DIKA 3PN1A 1ZAUA 4I55F 4UCSA 3TEKA 3KAKA 4GLXA 4YJ3F 2W6NA 4RZQA 1EYZA 2FPGB 3JRWA 4O7SA 5H80A 5FPRA 4FE2A 4MA0A 3QQMA 3V4SA 3SNOA 1A0IA 2I80A 3LQSA 3T9CA 5D8DA 3BA9A 3TY8A 2YWVA 3RR5A 3R5HA 2YS7A 3UZBA 2PBZA 3K3PA 5J2UF 1E4EA 3T9FA 1Z2OX 5GONF 2FPIB 1A3GA 1DV1A 2EJ0A 4IZOA 3R9RA 2VUGA 1CE8A 2VPQA 4EGJA 5BYBA 4O81A 5KKNB 4PZ6A 3RV4A 5BWUA 5LXTF 5I5VA 1T36A 5K3WA 2QB5A 3MWDA 5JQWA 1A48A 1EUDB 5EZYF 2CNUA 3LP8A 4TV9F 3GDEA 4IWXA 3AW8A 4C5CA 5JH7F 4FFPA 2A1HA 4FFLA 4MV3A 3UFXB 4NYEA 3TW7A 5I5UA 4XYLB 1E4EB 1GSHA 4NZOA 1VKZA 1X9NA 4O82A 1I1KA 2GPWA 2V58A 2R87A 3KALA 4GLWA 2DAAA 4FFMA 2HGSA 3VMMA 2CFMA 2NU6B 4IIJF 1TAEA 3K5IA 1UC9A 4ZOLF 4K6NA 3TW6A 1AUXA 3JZIA 1CKOA 1CKMA 5C1OA 2W6MA 4MA5A 2HG8A 3QWUA 4XYMB 1A0GA 3GB8B 4EFBA 1BNCA 2R7KA 2R82A 1EKVA 2C00A 5JQGF 2GLTA 4O7TA 2YL2A 4IHJF 1KT8A 1EKPA 2VQDA 5BMVF 2HVSA 4DLKA 4MV8A 4O7YA 5D1PA 3VOTA 1ULZA 3TY5A 3UQ8A 5C8YF 2WYOA 1GLVA 1VBHA 5BWWA 1Z2PX 2YZMA 4FU0A 2PVPA 2V59A 5BWVA 5IYZF 4PZ8A 4CKCA 2HHFB 5CM0A 2DZDA 3WO1A 2DABA 3JRXA 4O7LA 2YS6A 1VS0A 4MV9A 4MV4A 4O86A 3V4ZA 5HBRB 3JSLA 1CQJB 2CNVA 3HT5A 4YB8B 4ZQIA 4WBNF 3U0GA 4CKBA 1GGOA 3DF7A 3RFCA 3N6RA 3SE7A 3K5HA 5DGHA 5CB4F 1JKJB 2COGA 1CKNA 4O2BF 3U54A 4FFRA 2YW2A 3SGIA 4CC6A 1P8LA 3BA8A 2R84A 4FGRA 1KTAA 1G2WA 2FB9A 3RUPA 2COIA 1WR2A 2VR1A 3HO8A 3W5OA 1IOWA 3G8CA 5K2MA 4O7NA 4MAMA 3NBYB 1KEEA 2FPPB 2COJA 5E25A 2ZGIA 5LA6F 5BPHA 2ZDQA 1I7LA 5I5YA 3BG5A 4EQ5A 5CA1F 5DGIA 3VA7A 4C5AA 2XCLA 2Q2UA 4DIMA 1CKNB 2YZGA 1KJ8A 4TM5A 3RV3A 3TINA 3E5NA 5BWXA 2ZDGA 5I5XA 3AX6A 2OLSA 2R86A 3U55A 4O4IF 4ZI7F 1AUVA 3JZ6A 4PBCA 5KS8A 4C5BA 3VPBA 4O4LF 3R5FA 2NU9B 2W6ZA 2EJ3A 1VBGA 3S24A 3JSNA 3TIIA 2NU7B 2Y4RA 2SCUB 4EGQA 1CS0A 1P16A 1KJQA 3HB9A 4HQ6A 3MJFA 1KUTA 4JXUA 2J9GA 5CAEB 2R85A 4CE5A 2Z02A 2DLNA 3ETJA 5C1PA 1EHIA 2Z04A 2X5RA 3BABA 2R7NA 2YZLA 4E4TA 1KC7A 4O2AF 2I8CA 5CE8A 1ET0A 1GSOA 3BAAA 2HIVA 2CNQA 4UUGA 4CMDA 3U9SA 3WWJA 3DTFA 4UCOA 3T9EA 4UCUA 4EG0A 5JVDF 4RCNA 3LULA 1C3OA 1OBGA 1M6VA 4O7RA 4O83A 1GSAA 1UC8A 4ZHQF 2HDKA 5I5TA 3NUAA 2EIYA 1TA8A 2YZNA 3UYYA 4ME6A 5FNVF 3Q1KA 2HIXA 3T7AA 3T9AA 3GLKA 4NZNA 4O4HF 3MWEA 5HNEA 4UFZA 1A9XA 2IP4A 5LP6F 1XK5A 2ODTX 1KJIA 5LOVF 3ORQA 1Z2NX 1FVIA 4WHXA 4UCTA 3QFFA 4HNVA 4TUYF 1B6SA 3WO0A 5I5WA 1IYDA 3OUZA 2ABJA 2QK4A 5LYJF 3L2PA 1IOVA 5I5SA 3W1GA 3CEBA 5FR9A 4M0JA 5D1OA 1C30A 4PZ7A 3DAAA 4YBZB 1BXRA 3G8DA 3U9TA 3R5XA 2HVRA 3TIGA 4O4JF 4YAJB 3T54A 4EFEA 3JZFA 3TY9A 2W70A 3KREA 2GQRA 3KYHC 1B6RA 5HV6A 4Q4DA 3VPCA 1I2KA 5DMXA 2W6QA 4Y8VB 4M9UA 5I60A 4CMFA 1EKFA 4E6NA 4HNTA 3T9BA 4HN2A 2PN1A 2DWCA 5D1OB 1PK8A 2FP4B 1M0WA 1DV2A 3T9DA 1KJ9A 4L1KA 3ORRA 4NZMA 5BWTA 5KX5F 4MV7A 4YJ2F 4DQNA 4LH6A 4MV1A 1I1LA 1KJJA 5DISC 2OWOA 3UZOA 5FPOA 2EJ2A 1V9PA 1I2LA 2HVQA 2I87A 2QF7A 5BPFA 3I12A 1S68A 1I1MA 1WRVA 3HBLA 3WWIA 3Q2OA 4Q4CA 2R7MA 1OBDA 1W96A 3R23A 5I47A 1W93A 4O84A 3OUUA 3BACA 2GPSA 5JVLA 2YRWA 1B04A 4TVIA 4DRFA 1DIKA 4O7ZA 3RTXA 5J2TF 1DAAA 4HR7A 2NU8B 3W1BA 1SCUB 2Q7DA 5BWRA 1PX2A 2W6OA 5CR5A 3LWBA 2HGWA 2Q2TA 2P0AA 3T99A 3WWHA 5DAAA 3N8DA 4O7WA 4DAAA 4UCRA 4CC5A 3VPDA 2HHFA 4FFOA 2GQSA 1IYEA 4EEQA 4CKEA 3KAJA 5CA0F 2NUAB 2W71A 4I4TF 2R7LA 4HNUA 2CZGA 2W6PA 4UCVA 3DTGA 3WNZA 1JDEA 2X0SA 4TV8F 3GIDA 3NC0B 1EZ1A 4QSHA 3TQTA 4FFNA 5BYAA 4MV6A 3NBZB 4I50F 1M0TA 2ZDHA 2XD4A 3PFFA 4O7VA 1XDNA 4YAKB 2YYAA 1I7NA 4XZ3B 1DGSA 3VNNA 4CHIA 1CQIB 2V5AA 3GJXB 2YRXA 1JDBB 4LH7A 2HJWA 3ETHA 3CSWA 4XX0B 1KBLA 2HGXA 4IWYA 1JLLB 1EUCB
chains in the Genus database with same CATH topology
2X5RA 1ZAUA 3T9DA 5BWWA 4NZMA 5BWTA 5CE8A 1ET0A 3TEKA 4DQNA 4UUGA 4CMDA 5BWVA 4CKCA 3WWJA 2HHFB 3DTFA 5CM0A 3T9EA 1I1LA 2DABA 4RCNA 3LULA 3QQMA 3UZOA 3SNOA 3LQSA 3T9CA 2EJ2A 3HT5A 1I2LA 1UC8A 2HDKA 1I1MA 1WRVA 4CKBA 5I5TA 3U0GA 3WWIA 3UZBA 4Q4CA 2EIYA 5DGHA 3UYYA 5I47A 3T9FA 2COGA 1A3GA 3BACA 3SGIA 3T7AA 2EJ0A 1KTAA 4TVIA 3T9AA 1G2WA 4NZNA 2COIA 5BYBA 5HNEA 1DAAA 5K2MA 2Q7DA 5BWUA 5BWRA 5CR5A 5I5VA 2ODTX 5K3WA 2QB5A 2HGWA 2COJA 5E25A 2ZGIA 3T99A 4WHXA 3WWHA 4IWXA 5DAAA 5I5YA 2A1HA 4DAAA 3VPDA 2HHFA 5DGIA 5I5WA 3TW7A 5I5UA 1IYDA 1IYEA 2ABJA 4NZOA 4CKEA 4TM5A 1I1KA 5BWXA 5I5XA 5I5SA 4GLWA 2DAAA 3CEBA 5FR9A 3DTGA 4M0JA 3JZ6A 4PBCA 5KS8A 3DAAA 1UC9A 4K6NA 2EJ3A 5BYAA 3T54A 2HG8A 2Y4RA 1A0GA 4Q4DA 1EKVA 1I2KA 3PFFA 5I60A 4JXUA 4CMFA 1EKFA 1KT8A 1EKPA 4CHIA 3T9BA 4HN2A 4CE5A 3CSWA 2HGXA 4IWYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SGI A;  4GLW A;  1ZAU A;  3BAC A; 
#chains in the Genus database with same CATH topology
 2DIK A;  3PN1 A;  1ZAU A;  4I55 F;  4UCS A;  3TEK A;  3KAK A;  4GLX A;  4YJ3 F;  2W6N A;  4RZQ A;  1EYZ A;  2FPG B;  3JRW A;  4O7S A;  5H80 A;  5FPR A;  4FE2 A;  4MA0 A;  3QQM A;  3V4S A;  3SNO A;  1A0I A;  2I80 A;  3LQS A;  3T9C A;  5D8D A;  3BA9 A;  3TY8 A;  2YWV A;  3RR5 A;  3R5H A;  2YS7 A;  3UZB A;  2PBZ A;  3K3P A;  5J2U F;  1E4E A;  3T9F A;  1Z2O X;  5GON F;  2FPI B;  1A3G A;  1DV1 A;  2EJ0 A;  4IZO A;  3R9R A;  2VUG A;  1CE8 A;  2VPQ A;  4EGJ A;  5BYB A;  4O81 A;  5KKN B;  4PZ6 A;  3RV4 A;  5BWU A;  5LXT F;  5I5V A;  1T36 A;  5K3W A;  2QB5 A;  3MWD A;  5JQW A;  1A48 A;  1EUD B;  5EZY F;  2CNU A;  3LP8 A;  4TV9 F;  3GDE A;  4IWX A;  3AW8 A;  4C5C A;  5JH7 F;  4FFP A;  2A1H A;  4FFL A;  4MV3 A;  3UFX B;  4NYE A;  3TW7 A;  5I5U A;  4XYL B;  1E4E B;  1GSH A;  4NZO A;  1VKZ A;  1X9N A;  4O82 A;  1I1K A;  2GPW A;  2V58 A;  2R87 A;  3KAL A;  4GLW A;  2DAA A;  4FFM A;  2HGS A;  3VMM A;  2CFM A;  2NU6 B;  4IIJ F;  1TAE A;  3K5I A;  1UC9 A;  4ZOL F;  4K6N A;  3TW6 A;  1AUX A;  3JZI A;  1CKO A;  1CKM A;  5C1O A;  2W6M A;  4MA5 A;  2HG8 A;  3QWU A;  4XYM B;  1A0G A;  3GB8 B;  4EFB A;  1BNC A;  2R7K A;  2R82 A;  1EKV A;  2C00 A;  5JQG F;  2GLT A;  4O7T A;  2YL2 A;  4IHJ F;  1KT8 A;  1EKP A;  2VQD A;  5BMV F;  2HVS A;  4DLK A;  4MV8 A;  4O7Y A;  5D1P A;  3VOT A;  1ULZ A;  3TY5 A;  3UQ8 A;  5C8Y F;  2WYO A;  1GLV A;  1VBH A;  5BWW A;  1Z2P X;  2YZM A;  4FU0 A;  2PVP A;  2V59 A;  5BWV A;  5IYZ F;  4PZ8 A;  4CKC A;  2HHF B;  5CM0 A;  2DZD A;  3WO1 A;  2DAB A;  3JRX A;  4O7L A;  2YS6 A;  1VS0 A;  4MV9 A;  4MV4 A;  4O86 A;  3V4Z A;  5HBR B;  3JSL A;  1CQJ B;  2CNV A;  3HT5 A;  4YB8 B;  4ZQI A;  4WBN F;  3U0G A;  4CKB A;  1GGO A;  3DF7 A;  3RFC A;  3N6R A;  3SE7 A;  3K5H A;  5DGH A;  5CB4 F;  1JKJ B;  2COG A;  1CKN A;  4O2B F;  3U54 A;  4FFR A;  2YW2 A;  3SGI A;  4CC6 A;  1P8L A;  3BA8 A;  2R84 A;  4FGR A;  1KTA A;  1G2W A;  2FB9 A;  3RUP A;  2COI A;  1WR2 A;  2VR1 A;  3HO8 A;  3W5O A;  1IOW A;  3G8C A;  5K2M A;  4O7N A;  4MAM A;  3NBY B;  1KEE A;  2FPP B;  2COJ A;  5E25 A;  2ZGI A;  5LA6 F;  5BPH A;  2ZDQ A;  1I7L A;  5I5Y A;  3BG5 A;  4EQ5 A;  5CA1 F;  5DGI A;  3VA7 A;  4C5A A;  2XCL A;  2Q2U A;  4DIM A;  1CKN B;  2YZG A;  1KJ8 A;  4TM5 A;  3RV3 A;  3TIN A;  3E5N A;  5BWX A;  2ZDG A;  5I5X A;  3AX6 A;  2OLS A;  2R86 A;  3U55 A;  4O4I F;  4ZI7 F;  1AUV A;  3JZ6 A;  4PBC A;  5KS8 A;  4C5B A;  3VPB A;  4O4L F;  3R5F A;  2NU9 B;  2W6Z A;  2EJ3 A;  1VBG A;  3S24 A;  3JSN A;  3TII A;  2NU7 B;  2Y4R A;  2SCU B;  4EGQ A;  1CS0 A;  1P16 A;  1KJQ A;  3HB9 A;  4HQ6 A;  3MJF A;  1KUT A;  4JXU A;  2J9G A;  5CAE B;  2R85 A;  4CE5 A;  2Z02 A;  2DLN A;  3ETJ A;  5C1P A;  1EHI A;  2Z04 A;  2X5R A;  3BAB A;  2R7N A;  2YZL A;  4E4T A;  1KC7 A;  4O2A F;  2I8C A;  5CE8 A;  1ET0 A;  1GSO A;  3BAA A;  2HIV A;  2CNQ A;  4UUG A;  4CMD A;  3U9S A;  3WWJ A;  3DTF A;  4UCO A;  3T9E A;  4UCU A;  4EG0 A;  5JVD F;  4RCN A;  3LUL A;  1C3O A;  1OBG A;  1M6V A;  4O7R A;  4O83 A;  1GSA A;  1UC8 A;  4ZHQ F;  2HDK A;  5I5T A;  3NUA A;  2EIY A;  1TA8 A;  2YZN A;  3UYY A;  4ME6 A;  5FNV F;  3Q1K A;  2HIX A;  3T7A A;  3T9A A;  3GLK A;  4NZN A;  4O4H F;  3MWE A;  5HNE A;  4UFZ A;  1A9X A;  2IP4 A;  5LP6 F;  1XK5 A;  2ODT X;  1KJI A;  5LOV F;  3ORQ A;  1Z2N X;  1FVI A;  4WHX A;  4UCT A;  3QFF A;  4HNV A;  4TUY F;  1B6S A;  3WO0 A;  5I5W A;  1IYD A;  3OUZ A;  2ABJ A;  2QK4 A;  5LYJ F;  3L2P A;  1IOV A;  5I5S A;  3W1G A;  3CEB A;  5FR9 A;  4M0J A;  5D1O A;  1C30 A;  4PZ7 A;  3DAA A;  4YBZ B;  1BXR A;  3G8D A;  3U9T A;  3R5X A;  2HVR A;  3TIG A;  4O4J F;  4YAJ B;  3T54 A;  4EFE A;  3JZF A;  3TY9 A;  2W70 A;  3KRE A;  2GQR A;  3KYH C;  1B6R A;  5HV6 A;  4Q4D A;  3VPC A;  1I2K A;  5DMX A;  2W6Q A;  4Y8V B;  4M9U A;  5I60 A;  4CMF A;  1EKF A;  4E6N A;  4HNT A;  3T9B A;  4HN2 A;  2PN1 A;  2DWC A;  5D1O B;  1PK8 A;  2FP4 B;  1M0W A;  1DV2 A;  3T9D A;  1KJ9 A;  4L1K A;  3ORR A;  4NZM A;  5BWT A;  5KX5 F;  4MV7 A;  4YJ2 F;  4DQN A;  4LH6 A;  4MV1 A;  1I1L A;  1KJJ A;  5DIS C;  2OWO A;  3UZO A;  5FPO A;  2EJ2 A;  1V9P A;  1I2L A;  2HVQ A;  2I87 A;  2QF7 A;  5BPF A;  3I12 A;  1S68 A;  1I1M A;  1WRV A;  3HBL A;  3WWI A;  3Q2O A;  4Q4C A;  2R7M A;  1OBD A;  1W96 A;  3R23 A;  5I47 A;  1W93 A;  4O84 A;  3OUU A;  3BAC A;  2GPS A;  5JVL A;  2YRW A;  1B04 A;  4TVI A;  4DRF A;  1DIK A;  4O7Z A;  3RTX A;  5J2T F;  1DAA A;  4HR7 A;  2NU8 B;  3W1B A;  1SCU B;  2Q7D A;  5BWR A;  1PX2 A;  2W6O A;  5CR5 A;  3LWB A;  2HGW A;  2Q2T A;  2P0A A;  3T99 A;  3WWH A;  5DAA A;  3N8D A;  4O7W A;  4DAA A;  4UCR A;  4CC5 A;  3VPD A;  2HHF A;  4FFO A;  2GQS A;  1IYE A;  4EEQ A;  4CKE A;  3KAJ A;  5CA0 F;  2NUA B;  2W71 A;  4I4T F;  2R7L A;  4HNU A;  2CZG A;  2W6P A;  4UCV A;  3DTG A;  3WNZ A;  1JDE A;  2X0S A;  4TV8 F;  3GID A;  3NC0 B;  1EZ1 A;  4QSH A;  3TQT A;  4FFN A;  5BYA A;  4MV6 A;  3NBZ B;  4I50 F;  1M0T A;  2ZDH A;  2XD4 A;  3PFF A;  4O7V A;  1XDN A;  4YAK B;  2YYA A;  1I7N A;  4XZ3 B;  1DGS A;  3VNN A;  4CHI A;  1CQI B;  2V5A A;  3GJX B;  2YRX A;  1JDB B;  4LH7 A;  2HJW A;  3ETH A;  3CSW A;  4XX0 B;  1KBL A;  2HGX A;  4IWY A;  1JLL B;  1EUC B; 
#chains in the Genus database with same CATH homology
 2X5R A;  1ZAU A;  3T9D A;  5BWW A;  4NZM A;  5BWT A;  5CE8 A;  1ET0 A;  3TEK A;  4DQN A;  4UUG A;  4CMD A;  5BWV A;  4CKC A;  3WWJ A;  2HHF B;  3DTF A;  5CM0 A;  3T9E A;  1I1L A;  2DAB A;  4RCN A;  3LUL A;  3QQM A;  3UZO A;  3SNO A;  3LQS A;  3T9C A;  2EJ2 A;  3HT5 A;  1I2L A;  1UC8 A;  2HDK A;  1I1M A;  1WRV A;  4CKB A;  5I5T A;  3U0G A;  3WWI A;  3UZB A;  4Q4C A;  2EIY A;  5DGH A;  3UYY A;  5I47 A;  3T9F A;  2COG A;  1A3G A;  3BAC A;  3SGI A;  3T7A A;  2EJ0 A;  1KTA A;  4TVI A;  3T9A A;  1G2W A;  4NZN A;  2COI A;  5BYB A;  5HNE A;  1DAA A;  5K2M A;  2Q7D A;  5BWU A;  5BWR A;  5CR5 A;  5I5V A;  2ODT X;  5K3W A;  2QB5 A;  2HGW A;  2COJ A;  5E25 A;  2ZGI A;  3T99 A;  4WHX A;  3WWH A;  4IWX A;  5DAA A;  5I5Y A;  2A1H A;  4DAA A;  3VPD A;  2HHF A;  5DGI A;  5I5W A;  3TW7 A;  5I5U A;  1IYD A;  1IYE A;  2ABJ A;  4NZO A;  4CKE A;  4TM5 A;  1I1K A;  5BWX A;  5I5X A;  5I5S A;  4GLW A;  2DAA A;  3CEB A;  5FR9 A;  3DTG A;  4M0J A;  3JZ6 A;  4PBC A;  5KS8 A;  3DAA A;  1UC9 A;  4K6N A;  2EJ3 A;  5BYA A;  3T54 A;  2HG8 A;  2Y4R A;  1A0G A;  4Q4D A;  1EKV A;  1I2K A;  3PFF A;  5I60 A;  4JXU A;  4CMF A;  1EKF A;  1KT8 A;  1EKP A;  4CHI A;  3T9B A;  4HN2 A;  4CE5 A;  3CSW A;  2HGX A;  4IWY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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