3BACA

Structural basis for the inhibition of bacterial nad+ dependent dna ligase
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
255
structure length
255
Chain Sequence
GFSQIRHEIPMLSLDNAFSDAEFNAFVKRIEDRLILLPKPLTFCCEPKLDGLAVSILYVNGELTQAATRGDGTTGEDITANIRTIRNVPLQLLTDNPPARLEVRGEVFMPHAGFERLNKYALEHNEKTFANPRNAAAGSLRQLDPNITSKRPLVLNAYGIGIAEGVGLPTTHYARLQWLKSIGIPVNPEIRLCNGADEVLDFYQDIQNKRSSLGYDIDGTVLKINDIALQNELGFISKAPRWAIAYKFPAQEELT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for the Inhibition of Bacterial NAD+ Dependent DNA Ligase
rcsb
molecule tags Ligase
source organism Haemophilus influenzae
molecule keywords DNA ligase
total genus 67
structure length 255
sequence length 255
ec nomenclature ec 6.5.1.2: DNA ligase (NAD(+)).
pdb deposition date 2007-11-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.470.90 Alpha Beta 2-Layer Sandwich D-amino Acid Aminotransferase; Chain A, domain 1 D-amino Acid Aminotransferase; Chain A, domain 1 3bacA01
4GLWA 3BACA 3SGIA 1ZAUA
chains in the Genus database with same CATH superfamily
5HBRB 1XDNA 2HVRA 2V5AA 4MA5A 4O82A 5I47A 1T36A 1BXRA 4GLXA 1I1KA 3I12A 2DAAA 4IWXA 1I1MA 4CMDA 1ULZA 1JLLB 5E25A 2DZDA 4FU0A 2CFMA 4E4TA 4FFMA 3BAAA 3HT5A 5BWVA 3LULA 2DIKA 3G8DA 3KREA 2GQRA 2ZGIA 1EYZA 2XD4A 4UFZA 4DAAA 3VPDA 3TW7A 4O2AF 2VPQA 4O7WA 1DAAA 1TA8A 3TINA 2DLNA 4PZ6A 3WWIA 3GJXB 1IYDA 2YS6A 2ZDGA 3U55A 1M0WA 1CKNA 2V59A 1KJ8A 1GGOA 4M0JA 3CSWA 3T9EA 3MWEA 3SE7A 5I5VA 2CNUA 2NU8B 5BWWA 1EUCB 4YBZB 2I87A 1PK8A 4XYLB 2R7MA 4EFEA 2W70A 5D1OA 3K5IA 4HN2A 4MV9A 3JSLA 1C30A 3VPBA 3NC0B 3GIDA 5J2UF 1B6SA 2OWOA 2X0SA 5IYZF 4O83A 1GSAA 3LWBA 2PVPA 3TW6A 4CC6A 3N8DA 3WO0A 3HB9A 1WR2A 3QWUA 1CQIB 3CEBA 5C1OA 1FVIA 4TUYF 3SNOA 1A0IA 3NUAA 5BPHA 2I80A 4GLWA 2YRXA 5BWXA 3JRWA 4EGQA 1I7LA 4MV6A 3T9BA 4Q4DA 3RFCA 4DQNA 1M0TA 4CKEA 4HNTA 5LYJF 2HHFA 2QF7A 2ODTX 3W5OA 3N6RA 3RR5A 1I1LA 3JSNA 2PBZA 5D1PA 3BABA 5I5XA 3V4SA 3WWJA 1KJQA 5I5TA 5BYAA 5I5UA 3BG5A 2CZGA 3V4ZA 5CB4F 3AW8A 4HR7A 3VPCA 3DF7A 5BWUA 1GSOA 4O7LA 1GLVA 4FFPA 2Q2UA 1TAEA 2FPPB 3U54A 2I8CA 1KJ9A 3U9TA 1BNCA 1A48A 2W6PA 2FB9A 5BWTA 4O4IF 3WNZA 4RZQA 1KEEA 1KUTA 2J9GA 1VS0A 4O4LF 3RV4A 2YZMA 3RUPA 4EEQA 2FPIB 4CMFA 4FFNA 1VBGA 4TVIA 4NZOA 5FNVF 4YB8B 2P0AA 4UCOA 1AUVA 3E5NA 2W6NA 4PZ7A 3R5XA 2VR1A 4Q4CA 4C5BA 4ZHQF 1EKFA 5FPOA 2R85A 2A1HA 2HIVA 3WWHA 4CHIA 4LH7A 3UFXB 3TY9A 5CE8A 2Z02A 4UCUA 2QB5A 4FGRA 5I5WA 3KAKA 4O7YA 4K6NA 4XX0B 5K2MA 2NU6B 4O81A 1Z2PX 3AX6A 2W6MA 2CNQA 5BMVF 4IIJF 2R86A 1Z2OX 4UUGA 4E6NA 4EG0A 2DABA 5HV6A 5DISC 5CA1F 1IYEA 2HJWA 5FPRA 4YAKB 5DGHA 1CKMA 3TIGA 1IOWA 4IWYA 3VMMA 4JXUA 5LOVF 3MJFA 4MV1A 3KAJA 2R7NA 5CM0A 2ABJA 2IP4A 2SCUB 1CS0A 4RCNA 2W6ZA 4O4JF 3JRXA 3ETHA 3RV3A 2YZLA 4DRFA 1E4EB 4CE5A 4O4HF 1XK5A 2HIXA 1EZ1A 2QK4A 3OUUA 1ZAUA 3NBYB 1CE8A 1EKVA 3T7AA 1W93A 1JDEA 3U9SA 3TIIA 3R23A 1M6VA 4O7ZA 5JH7F 5I5YA 5KKNB 4EGJA 3T9CA 4LH6A 2R82A 3OUZA 1DV2A 3VOTA 5DMXA 2GPSA 4O7RA 5FR9A 5HNEA 5LXTF 3T9DA 3T99A 3GB8B 3ORRA 4NZMA 3TQTA 2R7LA 4ME6A 4I50F 5LA6F 4FFOA 2C00A 3G8CA 2FPGB 2YL2A 2FP4B 2XCLA 5CR5A 4FE2A 2ZDHA 4O7SA 3WO1A 3BA9A 1EKPA 3Q2OA 4WBNF 1G2WA 2Q2TA 1W96A 5C1PA 3VNNA 5JVDF 5BPFA 3ORQA 1VBHA 2VQDA 3RTXA 1DGSA 3BA8A 5DGIA 5I60A 3Q1KA 5KX5F 1OBDA 2EIYA 1CKOA 3L2PA 4NYEA 3UZBA 2GLTA 1I2LA 1JKJB 2W6QA 2OLSA 4I4TF 4FFLA 3NBZB 4CC5A 4MAMA 4UCRA 1PX2A 4O7VA 4YJ3F 2YYAA 2EJ0A 2V58A 5CAEB 5JQGF 4MV4A 4O7TA 5GONF 3U0GA 2YZGA 3UYYA 1Z2NX 3HO8A 3T9AA 1CQJB 1I7NA 2HGXA 4FFRA 1V9PA 5J2TF 4MV3A 2EJ2A 1KC7A 3JZ6A 4YJ2F 2Z04A 4L1KA 4EQ5A 1C3OA 2PN1A 3R5FA 1WRVA 5H80A 3BACA 3KYHC 1A3GA 4UCSA 4Y8VB 3TY5A 1KJIA 4ZQIA 1KBLA 3T9FA 5BYBA 2VUGA 1I2KA 1KTAA 3LQSA 3DTFA 5KS8A 1P8LA 1DV1A 1SCUB 3ETJA 4TM5A 3LP8A 2NU7B 2HVQA 3JZFA 4MV8A 1CKNB 4ZOLF 4HNUA 4C5CA 1EUDB 2GPWA 2YW2A 4IZOA 4PZ8A 2X5RA 4NZNA 1B04A 2YWVA 1EHIA 2HDKA 4DIMA 4O2BF 2W71A 1UC9A 3K3PA 2WYOA 5C8YF 5D1OB 1S68A 2R87A 5K3WA 1UC8A 4HQ6A 2HG8A 4XYMB 3W1BA 1E4EA 1VKZA 4TV9F 3TY8A 2ZDQA 3UQ8A 2EJ3A 3TEKA 1DIKA 1B6RA 4TV8F 1KJJA 1A9XA 4C5AA 5DAAA 4CKCA 3PFFA 1OBGA 3JZIA 2CNVA 2COGA 4CKBA 4EFBA 2Y4RA 3UZOA 3R5HA 3S24A 4WHXA 4IHJF 4YAJB 4M9UA 3R9RA 5JVLA 2W6OA 4UCTA 1P16A 4I55F 4QSHA 2YRWA 4DLKA 3QQMA 4O84A 3GDEA 3MWDA 4O7NA 3PN1A 2HHFB 1JDBB 4MA0A 1IOVA 3SGIA 2COJA 4ZI7F 3HBLA 2Q7DA 3K5HA 1AUXA 2GQSA 2R84A 3W1GA 4HNVA 2NUAB 1KT8A 2R7KA 2YZNA 5JQWA 4XZ3B 2DWCA 3GLKA 2HGWA 1ET0A 3QFFA 1GSHA 4PBCA 1A0GA 2HGSA 3DAAA 5I5SA 3T54A 3DTGA 4O86A 5BWRA 4MV7A 3KALA 2COIA 5EZYF 5D8DA 5CA0F 2YS7A 5LP6F 4UCVA 3VA7A 2NU9B 2HVSA 1X9NA
chains in the Genus database with same CATH topology
5BYBA 1I2KA 4RCNA 1KTAA 3LQSA 5I5XA 3DTFA 5KS8A 3WWJA 5I47A 5I5TA 4CE5A 5BYAA 5I5UA 4TM5A 1I1KA 2DAAA 4IWXA 1I1MA 4CMDA 1ZAUA 1EKVA 5E25A 5BWUA 3T7AA 3HT5A 5BWVA 3LULA 2X5RA 4NZNA 5I5YA 2ZGIA 2HDKA 1UC9A 5BWTA 3T9CA 4DAAA 3VPDA 3TW7A 5K3WA 1DAAA 1UC8A 2HG8A 5FR9A 5HNEA 3T9DA 3T99A 2EJ3A 4NZMA 3WWIA 1IYDA 3TEKA 4CMFA 4M0JA 4TVIA 3CSWA 5CR5A 5DAAA 4CKCA 3PFFA 3T9EA 2COGA 4CKBA 5I5VA 1EKPA 4NZOA 2Y4RA 1G2WA 5BWWA 3UZOA 4WHXA 4Q4CA 1EKFA 2A1HA 4HN2A 3WWHA 3QQMA 4CHIA 5DGIA 5I60A 2EIYA 5CE8A 3UZBA 2HHFB 1I2LA 3SGIA 2QB5A 2COJA 2Q7DA 5I5WA 4K6NA 5K2MA 1KT8A 3CEBA 4UUGA 2EJ0A 3SNOA 2DABA 2HGWA 3U0GA 1ET0A 4GLWA 3UYYA 4PBCA 1A0GA 5BWXA 1IYEA 3T9AA 3DAAA 5I5SA 3T54A 2HGXA 3DTGA 3T9BA 5BWRA 4Q4DA 2COIA 5DGHA 4DQNA 2EJ2A 3JZ6A 4CKEA 4IWYA 4JXUA 2HHFA 1WRVA 2ODTX 3BACA 1A3GA 5CM0A 1I1LA 2ABJA 3T9FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GLW A;  3BAC A;  3SGI A;  1ZAU A; 
#chains in the Genus database with same CATH topology
 5HBR B;  1XDN A;  2HVR A;  2V5A A;  4MA5 A;  4O82 A;  5I47 A;  1T36 A;  1BXR A;  4GLX A;  1I1K A;  3I12 A;  2DAA A;  4IWX A;  1I1M A;  4CMD A;  1ULZ A;  1JLL B;  5E25 A;  2DZD A;  4FU0 A;  2CFM A;  4E4T A;  4FFM A;  3BAA A;  3HT5 A;  5BWV A;  3LUL A;  2DIK A;  3G8D A;  3KRE A;  2GQR A;  2ZGI A;  1EYZ A;  2XD4 A;  4UFZ A;  4DAA A;  3VPD A;  3TW7 A;  4O2A F;  2VPQ A;  4O7W A;  1DAA A;  1TA8 A;  3TIN A;  2DLN A;  4PZ6 A;  3WWI A;  3GJX B;  1IYD A;  2YS6 A;  2ZDG A;  3U55 A;  1M0W A;  1CKN A;  2V59 A;  1KJ8 A;  1GGO A;  4M0J A;  3CSW A;  3T9E A;  3MWE A;  3SE7 A;  5I5V A;  2CNU A;  2NU8 B;  5BWW A;  1EUC B;  4YBZ B;  2I87 A;  1PK8 A;  4XYL B;  2R7M A;  4EFE A;  2W70 A;  5D1O A;  3K5I A;  4HN2 A;  4MV9 A;  3JSL A;  1C30 A;  3VPB A;  3NC0 B;  3GID A;  5J2U F;  1B6S A;  2OWO A;  2X0S A;  5IYZ F;  4O83 A;  1GSA A;  3LWB A;  2PVP A;  3TW6 A;  4CC6 A;  3N8D A;  3WO0 A;  3HB9 A;  1WR2 A;  3QWU A;  1CQI B;  3CEB A;  5C1O A;  1FVI A;  4TUY F;  3SNO A;  1A0I A;  3NUA A;  5BPH A;  2I80 A;  4GLW A;  2YRX A;  5BWX A;  3JRW A;  4EGQ A;  1I7L A;  4MV6 A;  3T9B A;  4Q4D A;  3RFC A;  4DQN A;  1M0T A;  4CKE A;  4HNT A;  5LYJ F;  2HHF A;  2QF7 A;  2ODT X;  3W5O A;  3N6R A;  3RR5 A;  1I1L A;  3JSN A;  2PBZ A;  5D1P A;  3BAB A;  5I5X A;  3V4S A;  3WWJ A;  1KJQ A;  5I5T A;  5BYA A;  5I5U A;  3BG5 A;  2CZG A;  3V4Z A;  5CB4 F;  3AW8 A;  4HR7 A;  3VPC A;  3DF7 A;  5BWU A;  1GSO A;  4O7L A;  1GLV A;  4FFP A;  2Q2U A;  1TAE A;  2FPP B;  3U54 A;  2I8C A;  1KJ9 A;  3U9T A;  1BNC A;  1A48 A;  2W6P A;  2FB9 A;  5BWT A;  4O4I F;  3WNZ A;  4RZQ A;  1KEE A;  1KUT A;  2J9G A;  1VS0 A;  4O4L F;  3RV4 A;  2YZM A;  3RUP A;  4EEQ A;  2FPI B;  4CMF A;  4FFN A;  1VBG A;  4TVI A;  4NZO A;  5FNV F;  4YB8 B;  2P0A A;  4UCO A;  1AUV A;  3E5N A;  2W6N A;  4PZ7 A;  3R5X A;  2VR1 A;  4Q4C A;  4C5B A;  4ZHQ F;  1EKF A;  5FPO A;  2R85 A;  2A1H A;  2HIV A;  3WWH A;  4CHI A;  4LH7 A;  3UFX B;  3TY9 A;  5CE8 A;  2Z02 A;  4UCU A;  2QB5 A;  4FGR A;  5I5W A;  3KAK A;  4O7Y A;  4K6N A;  4XX0 B;  5K2M A;  2NU6 B;  4O81 A;  1Z2P X;  3AX6 A;  2W6M A;  2CNQ A;  5BMV F;  4IIJ F;  2R86 A;  1Z2O X;  4UUG A;  4E6N A;  4EG0 A;  2DAB A;  5HV6 A;  5DIS C;  5CA1 F;  1IYE A;  2HJW A;  5FPR A;  4YAK B;  5DGH A;  1CKM A;  3TIG A;  1IOW A;  4IWY A;  3VMM A;  4JXU A;  5LOV F;  3MJF A;  4MV1 A;  3KAJ A;  2R7N A;  5CM0 A;  2ABJ A;  2IP4 A;  2SCU B;  1CS0 A;  4RCN A;  2W6Z A;  4O4J F;  3JRX A;  3ETH A;  3RV3 A;  2YZL A;  4DRF A;  1E4E B;  4CE5 A;  4O4H F;  1XK5 A;  2HIX A;  1EZ1 A;  2QK4 A;  3OUU A;  1ZAU A;  3NBY B;  1CE8 A;  1EKV A;  3T7A A;  1W93 A;  1JDE A;  3U9S A;  3TII A;  3R23 A;  1M6V A;  4O7Z A;  5JH7 F;  5I5Y A;  5KKN B;  4EGJ A;  3T9C A;  4LH6 A;  2R82 A;  3OUZ A;  1DV2 A;  3VOT A;  5DMX A;  2GPS A;  4O7R A;  5FR9 A;  5HNE A;  5LXT F;  3T9D A;  3T99 A;  3GB8 B;  3ORR A;  4NZM A;  3TQT A;  2R7L A;  4ME6 A;  4I50 F;  5LA6 F;  4FFO A;  2C00 A;  3G8C A;  2FPG B;  2YL2 A;  2FP4 B;  2XCL A;  5CR5 A;  4FE2 A;  2ZDH A;  4O7S A;  3WO1 A;  3BA9 A;  1EKP A;  3Q2O A;  4WBN F;  1G2W A;  2Q2T A;  1W96 A;  5C1P A;  3VNN A;  5JVD F;  5BPF A;  3ORQ A;  1VBH A;  2VQD A;  3RTX A;  1DGS A;  3BA8 A;  5DGI A;  5I60 A;  3Q1K A;  5KX5 F;  1OBD A;  2EIY A;  1CKO A;  3L2P A;  4NYE A;  3UZB A;  2GLT A;  1I2L A;  1JKJ B;  2W6Q A;  2OLS A;  4I4T F;  4FFL A;  3NBZ B;  4CC5 A;  4MAM A;  4UCR A;  1PX2 A;  4O7V A;  4YJ3 F;  2YYA A;  2EJ0 A;  2V58 A;  5CAE B;  5JQG F;  4MV4 A;  4O7T A;  5GON F;  3U0G A;  2YZG A;  3UYY A;  1Z2N X;  3HO8 A;  3T9A A;  1CQJ B;  1I7N A;  2HGX A;  4FFR A;  1V9P A;  5J2T F;  4MV3 A;  2EJ2 A;  1KC7 A;  3JZ6 A;  4YJ2 F;  2Z04 A;  4L1K A;  4EQ5 A;  1C3O A;  2PN1 A;  3R5F A;  1WRV A;  5H80 A;  3BAC A;  3KYH C;  1A3G A;  4UCS A;  4Y8V B;  3TY5 A;  1KJI A;  4ZQI A;  1KBL A;  3T9F A;  5BYB A;  2VUG A;  1I2K A;  1KTA A;  3LQS A;  3DTF A;  5KS8 A;  1P8L A;  1DV1 A;  1SCU B;  3ETJ A;  4TM5 A;  3LP8 A;  2NU7 B;  2HVQ A;  3JZF A;  4MV8 A;  1CKN B;  4ZOL F;  4HNU A;  4C5C A;  1EUD B;  2GPW A;  2YW2 A;  4IZO A;  4PZ8 A;  2X5R A;  4NZN A;  1B04 A;  2YWV A;  1EHI A;  2HDK A;  4DIM A;  4O2B F;  2W71 A;  1UC9 A;  3K3P A;  2WYO A;  5C8Y F;  5D1O B;  1S68 A;  2R87 A;  5K3W A;  1UC8 A;  4HQ6 A;  2HG8 A;  4XYM B;  3W1B A;  1E4E A;  1VKZ A;  4TV9 F;  3TY8 A;  2ZDQ A;  3UQ8 A;  2EJ3 A;  3TEK A;  1DIK A;  1B6R A;  4TV8 F;  1KJJ A;  1A9X A;  4C5A A;  5DAA A;  4CKC A;  3PFF A;  1OBG A;  3JZI A;  2CNV A;  2COG A;  4CKB A;  4EFB A;  2Y4R A;  3UZO A;  3R5H A;  3S24 A;  4WHX A;  4IHJ F;  4YAJ B;  4M9U A;  3R9R A;  5JVL A;  2W6O A;  4UCT A;  1P16 A;  4I55 F;  4QSH A;  2YRW A;  4DLK A;  3QQM A;  4O84 A;  3GDE A;  3MWD A;  4O7N A;  3PN1 A;  2HHF B;  1JDB B;  4MA0 A;  1IOV A;  3SGI A;  2COJ A;  4ZI7 F;  3HBL A;  2Q7D A;  3K5H A;  1AUX A;  2GQS A;  2R84 A;  3W1G A;  4HNV A;  2NUA B;  1KT8 A;  2R7K A;  2YZN A;  5JQW A;  4XZ3 B;  2DWC A;  3GLK A;  2HGW A;  1ET0 A;  3QFF A;  1GSH A;  4PBC A;  1A0G A;  2HGS A;  3DAA A;  5I5S A;  3T54 A;  3DTG A;  4O86 A;  5BWR A;  4MV7 A;  3KAL A;  2COI A;  5EZY F;  5D8D A;  5CA0 F;  2YS7 A;  5LP6 F;  4UCV A;  3VA7 A;  2NU9 B;  2HVS A;  1X9N A; 
#chains in the Genus database with same CATH homology
 5BYB A;  1I2K A;  4RCN A;  1KTA A;  3LQS A;  5I5X A;  3DTF A;  5KS8 A;  3WWJ A;  5I47 A;  5I5T A;  4CE5 A;  5BYA A;  5I5U A;  4TM5 A;  1I1K A;  2DAA A;  4IWX A;  1I1M A;  4CMD A;  1ZAU A;  1EKV A;  5E25 A;  5BWU A;  3T7A A;  3HT5 A;  5BWV A;  3LUL A;  2X5R A;  4NZN A;  5I5Y A;  2ZGI A;  2HDK A;  1UC9 A;  5BWT A;  3T9C A;  4DAA A;  3VPD A;  3TW7 A;  5K3W A;  1DAA A;  1UC8 A;  2HG8 A;  5FR9 A;  5HNE A;  3T9D A;  3T99 A;  2EJ3 A;  4NZM A;  3WWI A;  1IYD A;  3TEK A;  4CMF A;  4M0J A;  4TVI A;  3CSW A;  5CR5 A;  5DAA A;  4CKC A;  3PFF A;  3T9E A;  2COG A;  4CKB A;  5I5V A;  1EKP A;  4NZO A;  2Y4R A;  1G2W A;  5BWW A;  3UZO A;  4WHX A;  4Q4C A;  1EKF A;  2A1H A;  4HN2 A;  3WWH A;  3QQM A;  4CHI A;  5DGI A;  5I60 A;  2EIY A;  5CE8 A;  3UZB A;  2HHF B;  1I2L A;  3SGI A;  2QB5 A;  2COJ A;  2Q7D A;  5I5W A;  4K6N A;  5K2M A;  1KT8 A;  3CEB A;  4UUG A;  2EJ0 A;  3SNO A;  2DAB A;  2HGW A;  3U0G A;  1ET0 A;  4GLW A;  3UYY A;  4PBC A;  1A0G A;  5BWX A;  1IYE A;  3T9A A;  3DAA A;  5I5S A;  3T54 A;  2HGX A;  3DTG A;  3T9B A;  5BWR A;  4Q4D A;  2COI A;  5DGH A;  4DQN A;  2EJ2 A;  3JZ6 A;  4CKE A;  4IWY A;  4JXU A;  2HHF A;  1WRV A;  2ODT X;  3BAC A;  1A3G A;  5CM0 A;  1I1L A;  2ABJ A;  3T9F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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