The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
23
|
sequence length |
139
|
structure length |
124
|
Chain Sequence |
FYIETKLDGERMQMHKDGDVYKYFSRNGYNYTDQFGASPTELTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQKDLQTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKT
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structural insights into the role of domain flexibility in human DNA ligase IV
pubmed doi rcsb |
| molecule keywords |
DNA ligase 4
|
| molecule tags |
Ligase
|
| source organism |
Homo sapiens
|
| total genus |
23
|
| structure length |
124
|
| sequence length |
139
|
| ec nomenclature |
ec
6.5.1.1: DNA ligase (ATP). |
| pdb deposition date | 2012-01-17 |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | D-amino Acid Aminotransferase; Chain A, domain 1 | DNA ligase/mRNA capping enzyme |
#chains in the Genus database with same CATH superfamily 3VNN A; 4GLX A; 1VS0 A; 4CC5 A; 3TY8 A; 1XDN A; 5FPO A; 3GDE A; 3W5O A; 3BAA A; 3PN1 A; 3W1B A; 1CKO A; 4EEQ A; 3TY5 A; 1X9N A; 3TY9 A; 3BAB A; 4E6N A; 1V9P A; 2VUG A; 3S24 A; 4LH7 A; 5D1O A; 3NBY B; 3GB8 B; 1CKN B; 3JSL A; 2HVR A; 2CFM A; 4LH6 A; 3W1G A; 1P16 A; 5DIS C; 4EQ5 A; 4UCU A; 3L2P A; 1P8L A; 4PZ8 A; 4CC6 A; 4PZ7 A; 2Q2U A; 2HVQ A; 1S68 A; 1B04 A; 1A0I A; 3BA8 A; 3BA9 A; 4PZ6 A; 1FVI A; 1DGS A; 3JSN A; 5D1P A; 3NC0 B; 4DRF A; 3NBZ B; 3QWU A; 4UCS A; 2HVS A; 2HIX A; 1CKM A; 3GJX B; 4EFB A; 1XK5 A; 2Q2T A; 2OWO A; 3RTX A; 1TAE A; 4UFZ A; 1CKN A; 3UQ8 A; 3RR5 A; 2HIV A; 4UCV A; 4EFE A; 1TA8 A; 5FPR A; 4UCR A; 5D1O B; 4UCO A; 4UCT A; 3KYH C; #chains in the Genus database with same CATH topology 2COI A; 5J2U F; 3T9B A; 2W6M A; 2R87 A; 3HBL A; 3JRW A; 4XYL B; 3LQS A; 5BWR A; 4C5A A; 1KJ9 A; 3WNZ A; 4EGQ A; 3MJF A; 4I50 F; 2YS6 A; 4C5C A; 4I55 F; 4NZO A; 1IYE A; 1DAA A; 2YRX A; 5CAE B; 3TY5 A; 2EJ3 A; 1X9N A; 1GSH A; 4O7N A; 2EJ2 A; 2VUG A; 2NU9 B; 1I1M A; 5HBR B; 4FFR A; 3Q1K A; 4HNU A; 5D1O A; 3QFF A; 3AX6 A; 2YS7 A; 5GON F; 5C1O A; 3DTF A; 4TV8 F; 4RCN A; 2IP4 A; 5I5V A; 5DIS C; 4TM5 A; 2R85 A; 2HGW A; 4UCU A; 3L2P A; 4FFN A; 2FPG B; 5LA6 F; 3DF7 A; 3JZF A; 1SCU B; 5K3W A; 2DZD A; 3K5H A; 3N6R A; 5K2M A; 1KEE A; 2I8C A; 5LOV F; 2W6O A; 1E4E B; 3BG5 A; 3HB9 A; 3NBZ B; 2I87 A; 1CKM A; 4CKE A; 2Z02 A; 3WWJ A; 1I2K A; 1VKZ A; 3KAL A; 1I1K A; 4IIJ F; 3VA7 A; 2HGS A; 2Q2T A; 1KBL A; 3VPB A; 4MV7 A; 3T9C A; 2WYO A; 1DIK A; 4GLW A; 3UQ8 A; 4MV9 A; 3RR5 A; 4CMD A; 5BYB A; 4MA5 A; 3ORQ A; 4CKC A; 4PBC A; 2W6Q A; 1Z2P X; 5KX5 F; 4O4I F; 1TA8 A; 2R7M A; 5BWT A; 3TQT A; 3K5I A; 4EG0 A; 4FGR A; 1JKJ B; 2C00 A; 3HO8 A; 5HNE A; 4O2A F; 4IWX A; 4YJ2 F; 5DAA A; 4JXU A; 3VPD A; 4O7T A; 3U9T A; 4K6N A; 1M6V A; 1KJQ A; 4O7Z A; 3HT5 A; 3VNN A; 2R86 A; 5BMV F; 1VS0 A; 4YBZ B; 5I5Y A; 3CSW A; 3PFF A; 4ZOL F; 3ETH A; 1E4E A; 2OLS A; 1XDN A; 5FPO A; 2NU7 B; 3VOT A; 2HHF B; 4ME6 A; 3V4Z A; 1BXR A; 4DLK A; 1GGO A; 4DQN A; 3K3P A; 3MWD A; 1CKO A; 4Q4D A; 1W96 A; 5BYA A; 2R7K A; 5JQW A; 4O4J F; 3TY9 A; 3BAB A; 2GQS A; 2QF7 A; 3G8C A; 3V4S A; 1VBG A; 3T9D A; 2FPP B; 1ULZ A; 1VBH A; 5CM0 A; 4WHX A; 3NBY B; 5E25 A; 5JH7 F; 2A1H A; 2I80 A; 3LP8 A; 1GLV A; 3JSL A; 2V58 A; 5CR5 A; 2HVR A; 4MV6 A; 4NYE A; 1PK8 A; 2Q7D A; 4DAA A; 1AUX A; 4EGJ A; 1UC9 A; 1KUT A; 2COJ A; 2Q2U A; 4FFM A; 2HVQ A; 1B04 A; 2X5R A; 2FB9 A; 2R7N A; 3BA8 A; 3BA9 A; 4O7R A; 1DV2 A; 2HHF A; 2ZGI A; 2J9G A; 3T7A A; 1T36 A; 2ZDG A; 5CA0 F; 4HN2 A; 2R84 A; 4FE2 A; 2V5A A; 2HJW A; 2R82 A; 4QSH A; 5I60 A; 2YWV A; 2ZDQ A; 4HQ6 A; 1G2W A; 4MV4 A; 4I4T F; 3U9S A; 3ORR A; 3DAA A; 4UCS A; 1EKV A; 4FFP A; 1I2L A; 2XD4 A; 2CZG A; 1XK5 A; 2OWO A; 1TAE A; 4UFZ A; 3CEB A; 4O84 A; 4ZHQ F; 3AW8 A; 5I5U A; 4YAK B; 4O7V A; 4MV1 A; 5CB4 F; 1EUD B; 4O2B F; 5FPR A; 1WR2 A; 1KT8 A; 3T9A A; 3Q2O A; 1EZ1 A; 2VQD A; 1CQJ B; 1I1L A; 1C3O A; 1GSA A; 4M0J A; 1EUC B; 1A0G A; 1JLL B; 1JDB B; 2GPW A; 4HNV A; 3U54 A; 5I5S A; 4FFL A; 3KAJ A; 3BAC A; 4CC5 A; 1B6R A; 2ODT X; 3WO1 A; 1I7L A; 4MV8 A; 3GID A; 3TY8 A; 4CE5 A; 3SGI A; 2YZG A; 3GDE A; 1KC7 A; 5JQG F; 2R7L A; 4TV9 F; 3W5O A; 2DLN A; 3JRX A; 2VPQ A; 3TW7 A; 1Z2O X; 3W1B A; 2QK4 A; 2ZDH A; 2FP4 B; 2FPI B; 4E6N A; 1V9P A; 5LP6 F; 3E5N A; 3S24 A; 4Y8V B; 3T9F A; 4O7Y A; 4TVI A; 1C30 A; 3WWH A; 4O4H F; 2W71 A; 5BWU A; 3RUP A; 3SNO A; 3GB8 B; 3I12 A; 4LH6 A; 4IHJ F; 4O7S A; 3T99 A; 1P16 A; 4EQ5 A; 1A48 A; 1KJI A; 3WWI A; 3U55 A; 2GLT A; 5DMX A; 2W6Z A; 4IZO A; 1KJJ A; 2Y4R A; 3OUU A; 4RZQ A; 5I5W A; 1OBG A; 1BNC A; 1A0I A; 5LXT F; 1EKF A; 4M9U A; 4PZ6 A; 1UC8 A; 2GPS A; 4FU0 A; 3R9R A; 1DGS A; 5D1P A; 2PN1 A; 4CMF A; 3G8D A; 3GLK A; 1CS0 A; 1Z2N X; 3T9E A; 3QWU A; 2VR1 A; 1ET0 A; 2EJ0 A; 4MV3 A; 4NZM A; 5BWX A; 5I47 A; 2HIX A; 3GJX B; 5DGI A; 5KS8 A; 4EFB A; 4CHI A; 3UZB A; 4C5B A; 3RTX A; 1JDE A; 5IYZ F; 2PBZ A; 3ETJ A; 1I7N A; 4O82 A; 5I5X A; 4EFE A; 5BWW A; 4XYM B; 4YJ3 F; 4TUY F; 4YB8 B; 3RV4 A; 4UCR A; 2DWC A; 1CE8 A; 1M0W A; 2NU8 B; 4UCO A; 3KYH C; 4FFO A; 3R5H A; 2YZL A; 1W93 A; 4E4T A; 5BPF A; 4NZN A; 1KTA A; 4GLX A; 1EHI A; 1ZAU A; 5BPH A; 4MAM A; 5EZY F; 1IYD A; 1KJ8 A; 1B6S A; 1M0T A; 2ABJ A; 2DIK A; 3TIG A; 2NU6 B; 3UYY A; 3UZO A; 2PVP A; 3TII A; 3JZ6 A; 1AUV A; 4CKB A; 3T54 A; 5JVL A; 1EYZ A; 2W70 A; 5D8D A; 2HDK A; 3BAA A; 3PN1 A; 3R5X A; 3OUZ A; 2CNQ A; 5FR9 A; 4MA0 A; 4XZ3 B; 4EEQ A; 4ZI7 F; 1IOW A; 1A3G A; 3WO0 A; 5CE8 A; 4L1K A; 3VPC A; 2P0A A; 3RV3 A; 3U0G A; 2GQR A; 4O86 A; 2V59 A; 3JZI A; 4LH7 A; 3TEK A; 2DAA A; 2HGX A; 4UUG A; 3MWE A; 2CNU A; 1IOV A; 4YAJ B; 1DV1 A; 1CKN B; 1PX2 A; 2CFM A; 2DAB A; 1WRV A; 3W1G A; 3UFX B; 3DTG A; 2NUA B; 1P8L A; 4PZ8 A; 2W6P A; 4PZ7 A; 4CC6 A; 5C8Y F; 5FNV F; 1S68 A; 2XCL A; 4O4L F; 2SCU B; 2CNV A; 4HR7 A; 3VMM A; 5CA1 F; 1A9X A; 4HNT A; 1FVI A; 1CQI B; 4O83 A; 3KRE A; 5KKN B; 2W6N A; 3N8D A; 5DGH A; 3LWB A; 3JSN A; 3NC0 B; 3SE7 A; 4DRF A; 1OBD A; 3TIN A; 4Q4C A; 4DIM A; 3RFC A; 3R5F A; 2HVS A; 2YW2 A; 2Z04 A; 3TW6 A; 3KAK A; 4XX0 B; 4O81 A; 5LYJ F; 2HG8 A; 5I5T A; 3LUL A; 5C1P A; 4O7L A; 1GSO A; 2YYA A; 2YRW A; 2COG A; 1CKN A; 5BWV A; 2HIV A; 4UCV A; 4WBN F; 2YZN A; 5H80 A; 4IWY A; 1EKP A; 3QQM A; 2QB5 A; 3R23 A; 2EIY A; 5D1O B; 5HV6 A; 4O7W A; 3NUA A; 2YL2 A; 4UCT A; 2YZM A; 5J2T F; 4ZQI A; 5JVD F; 2X0S A; #chains in the Genus database with same CATH homology 3VNN A; 4GLX A; 1VS0 A; 4CC5 A; 3TY8 A; 1XDN A; 5FPO A; 3GDE A; 3W5O A; 3BAA A; 3PN1 A; 3W1B A; 1CKO A; 4EEQ A; 3TY5 A; 1X9N A; 3TY9 A; 3BAB A; 4E6N A; 1V9P A; 2VUG A; 3S24 A; 4LH7 A; 5D1O A; 3NBY B; 3GB8 B; 1CKN B; 3JSL A; 2HVR A; 2CFM A; 4LH6 A; 3W1G A; 1P16 A; 5DIS C; 4EQ5 A; 4UCU A; 3L2P A; 1P8L A; 4PZ8 A; 4CC6 A; 4PZ7 A; 2Q2U A; 2HVQ A; 1S68 A; 1B04 A; 1A0I A; 3BA8 A; 3BA9 A; 4PZ6 A; 1FVI A; 1DGS A; 3JSN A; 5D1P A; 3NC0 B; 4DRF A; 3NBZ B; 3QWU A; 4UCS A; 2HVS A; 2HIX A; 1CKM A; 3GJX B; 4EFB A; 1XK5 A; 2Q2T A; 2OWO A; 3RTX A; 1TAE A; 4UFZ A; 1CKN A; 3UQ8 A; 3RR5 A; 2HIV A; 4UCV A; 4EFE A; 1TA8 A; 5FPR A; 4UCR A; 5D1O B; 4UCO A; 4UCT A; 3KYH C;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
