3BACA

Structural basis for the inhibition of bacterial nad+ dependent dna ligase
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
255
structure length
255
Chain Sequence
GFSQIRHEIPMLSLDNAFSDAEFNAFVKRIEDRLILLPKPLTFCCEPKLDGLAVSILYVNGELTQAATRGDGTTGEDITANIRTIRNVPLQLLTDNPPARLEVRGEVFMPHAGFERLNKYALEHNEKTFANPRNAAAGSLRQLDPNITSKRPLVLNAYGIGIAEGVGLPTTHYARLQWLKSIGIPVNPEIRLCNGADEVLDFYQDIQNKRSSLGYDIDGTVLKINDIALQNELGFISKAPRWAIAYKFPAQEELT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for the Inhibition of Bacterial NAD+ Dependent DNA Ligase
rcsb
molecule tags Ligase
source organism Haemophilus influenzae
molecule keywords DNA ligase
total genus 67
structure length 255
sequence length 255
ec nomenclature ec 6.5.1.2: DNA ligase (NAD(+)).
pdb deposition date 2007-11-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.470.90 Alpha Beta 2-Layer Sandwich D-amino Acid Aminotransferase; Chain A, domain 1 D-amino Acid Aminotransferase; Chain A, domain 1 3bacA01
1ZAUA 4GLWA 3BACA 3SGIA
chains in the Genus database with same CATH superfamily
3K3PA 2YZLA 1M6VA 5H80A 4O81A 3T9BA 1IOWA 2ZDQA 3HO8A 1ET0A 3HBLA 1M0WA 5HNEA 2R86A 2W6PA 2W6ZA 4UCUA 1KJQA 5BWUA 3U0GA 1EHIA 1EZ1A 2Q7DA 4DRFA 5LYJF 4Q4CA 3U55A 4CC6A 3R23A 1A0IA 2Z02A 2EJ3A 3CSWA 4K6NA 3RV3A 3TQTA 2V59A 2IP4A 3JRXA 2DIKA 4C5CA 1I2KA 5D8DA 2J9GA 3PN1A 3TIGA 4TV8F 4EG0A 1IOVA 5JH7F 5BPFA 3TY9A 2FPPB 1KUTA 2COIA 3N8DA 1AUVA 3L2PA 1CKMA 1BXRA 3WWIA 2DABA 4O7TA 1E4EA 5LA6F 3NBZB 3W1GA 4C5BA 4CHIA 3DAAA 3GJXB 4MA5A 3V4ZA 1VBGA 5J2TF 2R82A 3TY8A 3NUAA 1Z2OX 4NYEA 2PBZA 2A1HA 4CC5A 3UFXB 4O2AF 4IHJF 3WO1A 3LWBA 5DGIA 4PZ8A 1G2WA 4O4JF 2R7NA 4DQNA 3LQSA 3T9EA 4HNUA 3G8DA 2XD4A 2R87A 5D1PA 3T9DA 3JSLA 4O83A 1ZAUA 1TAEA 1Z2NX 1A9XA 2GLTA 2HGSA 3T9FA 5D1OB 2I87A 5DGHA 3WNZA 1I7LA 3K5IA 3WWHA 4CMDA 5EZYF 3TIIA 5LOVF 4Y8VB 1KJIA 5I5WA 1M0TA 2YRXA 5LXTF 4L1KA 4ME6A 3WWJA 3G8CA 2YL2A 2W71A 3KREA 4YAJB 4MV6A 4C5AA 3K5HA 1UC8A 2NU6B 4O84A 1CKOA 1PK8A 5K2MA 3T7AA 5BYAA 1JDBB 3VPDA 1TA8A 1BNCA 1WR2A 5DMXA 4O86A 1IYDA 3BA9A 4O4IF 5BWVA 1XDNA 4JXUA 1Z2PX 4PZ7A 4HQ6A 1EUDB 5FPOA 2C00A 5E25A 5DISC 1CE8A 3KAJA 1P8LA 4O7LA 1B6RA 5CB4F 2YW2A 1KTAA 4PBCA 4XYLB 1WRVA 4LH7A 1I7NA 2W6QA 2ZDHA 3DF7A 4TVIA 3U9SA 1C3OA 4UCOA 4I55F 1KBLA 4LH6A 1DV2A 4FGRA 5C1OA 1CKNB 2DZDA 4TM5A 3RR5A 5J2UF 5JVLA 3Q2OA 1VS0A 5CAEB 2CNUA 3VNNA 4RZQA 4YB8B 4DIMA 5C8YF 3R5HA 2W6NA 2QB5A 3GLKA 3AW8A 3BA8A 4UCSA 5BMVF 1C30A 1JKJB 2GPSA 2W70A 2GQRA 4O2BF 5BWRA 3UZBA 3I12A 3JZIA 5I5UA 5HV6A 1CS0A 4YJ2F 5BWTA 3U9TA 3U54A 4MA0A 2FP4B 2CNVA 4MV8A 4UCRA 4XX0B 1W96A 2VPQA 2HVQA 1T36A 1A0GA 4O7NA 3VPCA 5CA0F 1I2LA 1GSHA 1CQJB 3Q1KA 3MJFA 1CQIB 1KJJA 1V9PA 2DWCA 3ETHA 4PZ6A 5GONF 3BG5A 2DLNA 2I80A 4YJ3F 5C1PA 1KT8A 4O7RA 4UFZA 3RTXA 5I47A 3QWUA 4UCTA 5I5VA 4RCNA 4ZHQF 4EQ5A 3GB8B 2WYOA 1DAAA 2ODTX 2VR1A 1I1LA 2NU7B 3TY5A 2HJWA 5FR9A 3WO0A 5JQWA 3LULA 4CKBA 3UYYA 4E4TA 3ORRA 2ZGIA 2FPIB 2YWVA 2QK4A 4O82A 4O7VA 4O4LF 4MV3A 4EGJA 4IWXA 5D1OA 3UZOA 3T54A 2VUGA 3T99A 2X5RA 3W1BA 1S68A 1AUXA 3V4SA 1KC7A 1EUCB 4M0JA 2HVRA 2W6MA 4DAAA 2HHFB 5HBRB 3JZ6A 1JLLB 4I50F 5CR5A 1KJ9A 1EKVA 1X9NA 2X0SA 5I5SA 4UUGA 4FFPA 5K3WA 1EKFA 3W5OA 3TEKA 5BWWA 3N6RA 1XK5A 5BPHA 4TUYF 3OUUA 2ABJA 2PN1A 1IYEA 4FFOA 4WHXA 3VMMA 4HNTA 3LP8A 2Z04A 2YS6A 3S24A 3DTFA 5LP6F 3ORQA 5KX5F 1P16A 3T9AA 1A48A 5CA1F 1GSOA 4EFEA 4HNVA 4MV1A 2V5AA 4WBNF 4XYMB 2CNQA 2EIYA 4FFMA 5I5YA 3TW7A 5CE8A 4IZOA 2R7LA 3R9RA 2YZGA 3T9CA 5CM0A 2R7KA 2HIVA 1CKNA 2W6OA 2QF7A 3KAKA 1SCUB 3NC0B 5I5TA 2EJ2A 2NU8B 1UC9A 2GPWA 4EGQA 2OLSA 3E5NA 1PX2A 1VBHA 1ULZA 4HN2A 1DIKA 2NUAB 3R5FA 4MAMA 4GLXA 3PFFA 4EFBA 3JRWA 4XZ3B 2XCLA 3OUZA 2Y4RA 3TW6A 2CZGA 3TINA 4M9UA 2HG8A 5BWXA 4MV4A 1DV1A 2OWOA 2YYAA 1EYZA 2YRWA 2HGWA 2COGA 5I60A 1A3GA 1GSAA 4Q4DA 1GLVA 4FFRA 3GDEA 4QSHA 4NZMA 5JQGF 1OBGA 3VPBA 4IIJF 3ETJA 4CMFA 4MV9A 1DGSA 4CE5A 2V58A 3QFFA 2DAAA 1E4EB 1OBDA 3JSNA 2NU9B 1JDEA 2FPGB 2Q2UA 5BYBA 3NBYB 5FNVF 2COJA 2R85A 4NZOA 3MWDA 3SE7A 4E6NA 2HIXA 1B04A 2EJ0A 4CKCA 4YAKB 3VA7A 4TV9F 4HR7A 2YZNA 4O7YA 2YZMA 3HT5A 4FE2A 4FFLA 3JZFA 1GGOA 4O7SA 4ZOLF 4MV7A 2GQSA 3R5XA 2Q2TA 5DAAA 2PVPA 3BACA 5KS8A 5IYZF 2R7MA 3SNOA 2R84A 4FFNA 4DLKA 4ZI7F 2YS7A 3DTGA 1KEEA 3QQMA 1W93A 3KALA 3HB9A 4NZNA 1KJ8A 2HVSA 2CFMA 2VQDA 5FPRA 1I1MA 2HHFA 5JVDF 2FB9A 2SCUB 2P0AA 3BABA 4O4HF 3RFCA 1B6SA 3AX6A 4I4TF 3KYHC 5I5XA 4YBZB 1FVIA 2HDKA 1I1KA 2HGXA 2ZDGA 1EKPA 4GLWA 3SGIA 4CKEA 1VKZA 4EEQA 5KKNB 4O7WA 3UQ8A 4O7ZA 3BAAA 4ZQIA 3MWEA 3RV4A 3CEBA 4UCVA 3VOTA 4IWYA 3GIDA 3RUPA 4FU0A 2I8CA
chains in the Genus database with same CATH topology
5FR9A 3VPDA 1A3GA 3LULA 4CKBA 3UYYA 3T9BA 4Q4DA 1ET0A 2ZGIA 1IYDA 4NZMA 5HNEA 5BWVA 4JXUA 5BWUA 3U0GA 4IWXA 5E25A 2Q7DA 4CMFA 3UZOA 3T54A 4CE5A 4Q4CA 2DAAA 3T99A 2X5RA 2EJ3A 3CSWA 4K6NA 5BYBA 2COJA 4NZOA 1KTAA 4PBCA 1WRVA 1I2KA 4M0JA 4TVIA 2EJ0A 4CKCA 4DAAA 2HHFB 3JZ6A 5CR5A 1EKVA 5I5SA 4UUGA 3HT5A 5K3WA 1EKFA 4TM5A 3TEKA 5BWWA 2COIA 3WWIA 2ABJA 2DABA 1IYEA 4WHXA 5DAAA 3BACA 5KS8A 3SNOA 3DTFA 3DTGA 4CHIA 3DAAA 2QB5A 3QQMA 3T9AA 4NZNA 5BWRA 3UZBA 1I1MA 2EIYA 2HHFA 5I5UA 2A1HA 5BWTA 5I5YA 5CE8A 3TW7A 5DGIA 1G2WA 3T9CA 4DQNA 5CM0A 3LQSA 3T9EA 5I5TA 2EJ2A 3T9DA 1ZAUA 5I5XA 1UC9A 1A0GA 3T9FA 1I2LA 4HN2A 5DGHA 2HDKA 3WWHA 1I1KA 2HGXA 3PFFA 4CMDA 1EKPA 4GLWA 3SGIA 4CKEA 2Y4RA 5I5WA 1KT8A 2HG8A 5BWXA 5I47A 3CEBA 5I5VA 3WWJA 4IWYA 4RCNA 1DAAA 2ODTX 2HGWA 1UC8A 2COGA 1I1LA 5I60A 5K2MA 3T7AA 5BYAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZAU A;  4GLW A;  3BAC A;  3SGI A; 
#chains in the Genus database with same CATH topology
 3K3P A;  2YZL A;  1M6V A;  5H80 A;  4O81 A;  3T9B A;  1IOW A;  2ZDQ A;  3HO8 A;  1ET0 A;  3HBL A;  1M0W A;  5HNE A;  2R86 A;  2W6P A;  2W6Z A;  4UCU A;  1KJQ A;  5BWU A;  3U0G A;  1EHI A;  1EZ1 A;  2Q7D A;  4DRF A;  5LYJ F;  4Q4C A;  3U55 A;  4CC6 A;  3R23 A;  1A0I A;  2Z02 A;  2EJ3 A;  3CSW A;  4K6N A;  3RV3 A;  3TQT A;  2V59 A;  2IP4 A;  3JRX A;  2DIK A;  4C5C A;  1I2K A;  5D8D A;  2J9G A;  3PN1 A;  3TIG A;  4TV8 F;  4EG0 A;  1IOV A;  5JH7 F;  5BPF A;  3TY9 A;  2FPP B;  1KUT A;  2COI A;  3N8D A;  1AUV A;  3L2P A;  1CKM A;  1BXR A;  3WWI A;  2DAB A;  4O7T A;  1E4E A;  5LA6 F;  3NBZ B;  3W1G A;  4C5B A;  4CHI A;  3DAA A;  3GJX B;  4MA5 A;  3V4Z A;  1VBG A;  5J2T F;  2R82 A;  3TY8 A;  3NUA A;  1Z2O X;  4NYE A;  2PBZ A;  2A1H A;  4CC5 A;  3UFX B;  4O2A F;  4IHJ F;  3WO1 A;  3LWB A;  5DGI A;  4PZ8 A;  1G2W A;  4O4J F;  2R7N A;  4DQN A;  3LQS A;  3T9E A;  4HNU A;  3G8D A;  2XD4 A;  2R87 A;  5D1P A;  3T9D A;  3JSL A;  4O83 A;  1ZAU A;  1TAE A;  1Z2N X;  1A9X A;  2GLT A;  2HGS A;  3T9F A;  5D1O B;  2I87 A;  5DGH A;  3WNZ A;  1I7L A;  3K5I A;  3WWH A;  4CMD A;  5EZY F;  3TII A;  5LOV F;  4Y8V B;  1KJI A;  5I5W A;  1M0T A;  2YRX A;  5LXT F;  4L1K A;  4ME6 A;  3WWJ A;  3G8C A;  2YL2 A;  2W71 A;  3KRE A;  4YAJ B;  4MV6 A;  4C5A A;  3K5H A;  1UC8 A;  2NU6 B;  4O84 A;  1CKO A;  1PK8 A;  5K2M A;  3T7A A;  5BYA A;  1JDB B;  3VPD A;  1TA8 A;  1BNC A;  1WR2 A;  5DMX A;  4O86 A;  1IYD A;  3BA9 A;  4O4I F;  5BWV A;  1XDN A;  4JXU A;  1Z2P X;  4PZ7 A;  4HQ6 A;  1EUD B;  5FPO A;  2C00 A;  5E25 A;  5DIS C;  1CE8 A;  3KAJ A;  1P8L A;  4O7L A;  1B6R A;  5CB4 F;  2YW2 A;  1KTA A;  4PBC A;  4XYL B;  1WRV A;  4LH7 A;  1I7N A;  2W6Q A;  2ZDH A;  3DF7 A;  4TVI A;  3U9S A;  1C3O A;  4UCO A;  4I55 F;  1KBL A;  4LH6 A;  1DV2 A;  4FGR A;  5C1O A;  1CKN B;  2DZD A;  4TM5 A;  3RR5 A;  5J2U F;  5JVL A;  3Q2O A;  1VS0 A;  5CAE B;  2CNU A;  3VNN A;  4RZQ A;  4YB8 B;  4DIM A;  5C8Y F;  3R5H A;  2W6N A;  2QB5 A;  3GLK A;  3AW8 A;  3BA8 A;  4UCS A;  5BMV F;  1C30 A;  1JKJ B;  2GPS A;  2W70 A;  2GQR A;  4O2B F;  5BWR A;  3UZB A;  3I12 A;  3JZI A;  5I5U A;  5HV6 A;  1CS0 A;  4YJ2 F;  5BWT A;  3U9T A;  3U54 A;  4MA0 A;  2FP4 B;  2CNV A;  4MV8 A;  4UCR A;  4XX0 B;  1W96 A;  2VPQ A;  2HVQ A;  1T36 A;  1A0G A;  4O7N A;  3VPC A;  5CA0 F;  1I2L A;  1GSH A;  1CQJ B;  3Q1K A;  3MJF A;  1CQI B;  1KJJ A;  1V9P A;  2DWC A;  3ETH A;  4PZ6 A;  5GON F;  3BG5 A;  2DLN A;  2I80 A;  4YJ3 F;  5C1P A;  1KT8 A;  4O7R A;  4UFZ A;  3RTX A;  5I47 A;  3QWU A;  4UCT A;  5I5V A;  4RCN A;  4ZHQ F;  4EQ5 A;  3GB8 B;  2WYO A;  1DAA A;  2ODT X;  2VR1 A;  1I1L A;  2NU7 B;  3TY5 A;  2HJW A;  5FR9 A;  3WO0 A;  5JQW A;  3LUL A;  4CKB A;  3UYY A;  4E4T A;  3ORR A;  2ZGI A;  2FPI B;  2YWV A;  2QK4 A;  4O82 A;  4O7V A;  4O4L F;  4MV3 A;  4EGJ A;  4IWX A;  5D1O A;  3UZO A;  3T54 A;  2VUG A;  3T99 A;  2X5R A;  3W1B A;  1S68 A;  1AUX A;  3V4S A;  1KC7 A;  1EUC B;  4M0J A;  2HVR A;  2W6M A;  4DAA A;  2HHF B;  5HBR B;  3JZ6 A;  1JLL B;  4I50 F;  5CR5 A;  1KJ9 A;  1EKV A;  1X9N A;  2X0S A;  5I5S A;  4UUG A;  4FFP A;  5K3W A;  1EKF A;  3W5O A;  3TEK A;  5BWW A;  3N6R A;  1XK5 A;  5BPH A;  4TUY F;  3OUU A;  2ABJ A;  2PN1 A;  1IYE A;  4FFO A;  4WHX A;  3VMM A;  4HNT A;  3LP8 A;  2Z04 A;  2YS6 A;  3S24 A;  3DTF A;  5LP6 F;  3ORQ A;  5KX5 F;  1P16 A;  3T9A A;  1A48 A;  5CA1 F;  1GSO A;  4EFE A;  4HNV A;  4MV1 A;  2V5A A;  4WBN F;  4XYM B;  2CNQ A;  2EIY A;  4FFM A;  5I5Y A;  3TW7 A;  5CE8 A;  4IZO A;  2R7L A;  3R9R A;  2YZG A;  3T9C A;  5CM0 A;  2R7K A;  2HIV A;  1CKN A;  2W6O A;  2QF7 A;  3KAK A;  1SCU B;  3NC0 B;  5I5T A;  2EJ2 A;  2NU8 B;  1UC9 A;  2GPW A;  4EGQ A;  2OLS A;  3E5N A;  1PX2 A;  1VBH A;  1ULZ A;  4HN2 A;  1DIK A;  2NUA B;  3R5F A;  4MAM A;  4GLX A;  3PFF A;  4EFB A;  3JRW A;  4XZ3 B;  2XCL A;  3OUZ A;  2Y4R A;  3TW6 A;  2CZG A;  3TIN A;  4M9U A;  2HG8 A;  5BWX A;  4MV4 A;  1DV1 A;  2OWO A;  2YYA A;  1EYZ A;  2YRW A;  2HGW A;  2COG A;  5I60 A;  1A3G A;  1GSA A;  4Q4D A;  1GLV A;  4FFR A;  3GDE A;  4QSH A;  4NZM A;  5JQG F;  1OBG A;  3VPB A;  4IIJ F;  3ETJ A;  4CMF A;  4MV9 A;  1DGS A;  4CE5 A;  2V58 A;  3QFF A;  2DAA A;  1E4E B;  1OBD A;  3JSN A;  2NU9 B;  1JDE A;  2FPG B;  2Q2U A;  5BYB A;  3NBY B;  5FNV F;  2COJ A;  2R85 A;  4NZO A;  3MWD A;  3SE7 A;  4E6N A;  2HIX A;  1B04 A;  2EJ0 A;  4CKC A;  4YAK B;  3VA7 A;  4TV9 F;  4HR7 A;  2YZN A;  4O7Y A;  2YZM A;  3HT5 A;  4FE2 A;  4FFL A;  3JZF A;  1GGO A;  4O7S A;  4ZOL F;  4MV7 A;  2GQS A;  3R5X A;  2Q2T A;  5DAA A;  2PVP A;  3BAC A;  5KS8 A;  5IYZ F;  2R7M A;  3SNO A;  2R84 A;  4FFN A;  4DLK A;  4ZI7 F;  2YS7 A;  3DTG A;  1KEE A;  3QQM A;  1W93 A;  3KAL A;  3HB9 A;  4NZN A;  1KJ8 A;  2HVS A;  2CFM A;  2VQD A;  5FPR A;  1I1M A;  2HHF A;  5JVD F;  2FB9 A;  2SCU B;  2P0A A;  3BAB A;  4O4H F;  3RFC A;  1B6S A;  3AX6 A;  4I4T F;  3KYH C;  5I5X A;  4YBZ B;  1FVI A;  2HDK A;  1I1K A;  2HGX A;  2ZDG A;  1EKP A;  4GLW A;  3SGI A;  4CKE A;  1VKZ A;  4EEQ A;  5KKN B;  4O7W A;  3UQ8 A;  4O7Z A;  3BAA A;  4ZQI A;  3MWE A;  3RV4 A;  3CEB A;  4UCV A;  3VOT A;  4IWY A;  3GID A;  3RUP A;  4FU0 A;  2I8C A; 
#chains in the Genus database with same CATH homology
 5FR9 A;  3VPD A;  1A3G A;  3LUL A;  4CKB A;  3UYY A;  3T9B A;  4Q4D A;  1ET0 A;  2ZGI A;  1IYD A;  4NZM A;  5HNE A;  5BWV A;  4JXU A;  5BWU A;  3U0G A;  4IWX A;  5E25 A;  2Q7D A;  4CMF A;  3UZO A;  3T54 A;  4CE5 A;  4Q4C A;  2DAA A;  3T99 A;  2X5R A;  2EJ3 A;  3CSW A;  4K6N A;  5BYB A;  2COJ A;  4NZO A;  1KTA A;  4PBC A;  1WRV A;  1I2K A;  4M0J A;  4TVI A;  2EJ0 A;  4CKC A;  4DAA A;  2HHF B;  3JZ6 A;  5CR5 A;  1EKV A;  5I5S A;  4UUG A;  3HT5 A;  5K3W A;  1EKF A;  4TM5 A;  3TEK A;  5BWW A;  2COI A;  3WWI A;  2ABJ A;  2DAB A;  1IYE A;  4WHX A;  5DAA A;  3BAC A;  5KS8 A;  3SNO A;  3DTF A;  3DTG A;  4CHI A;  3DAA A;  2QB5 A;  3QQM A;  3T9A A;  4NZN A;  5BWR A;  3UZB A;  1I1M A;  2EIY A;  2HHF A;  5I5U A;  2A1H A;  5BWT A;  5I5Y A;  5CE8 A;  3TW7 A;  5DGI A;  1G2W A;  3T9C A;  4DQN A;  5CM0 A;  3LQS A;  3T9E A;  5I5T A;  2EJ2 A;  3T9D A;  1ZAU A;  5I5X A;  1UC9 A;  1A0G A;  3T9F A;  1I2L A;  4HN2 A;  5DGH A;  2HDK A;  3WWH A;  1I1K A;  2HGX A;  3PFF A;  4CMD A;  1EKP A;  4GLW A;  3SGI A;  4CKE A;  2Y4R A;  5I5W A;  1KT8 A;  2HG8 A;  5BWX A;  5I47 A;  3CEB A;  5I5V A;  3WWJ A;  4IWY A;  4RCN A;  1DAA A;  2ODT X;  2HGW A;  1UC8 A;  2COG A;  1I1L A;  5I60 A;  5K2M A;  3T7A A;  5BYA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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