1HQ1A

Structural and energetic analysis of rna recognition by a universally conserved protein from the signal recognition particle
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
104
structure length
76
Chain Sequence
GFDLNDFLEQLRQDDKVLVRMEAIINSMTMKERAKPEIIKGSRKRRIAAGSGMQVQDVNRLLKQFDDMQRMMKKMK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and energetic analysis of RNA recognition by a universally conserved protein from the signal recognition particle.
pubmed doi rcsb
molecule tags Signaling protein/rna
source organism Escherichia coli
molecule keywords 4.5S RNA DOMAIN IV
total genus 28
structure length 76
sequence length 104
ec nomenclature
pdb deposition date 2000-12-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02978 SRP_SPB Signal peptide binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.260.30 Mainly Alpha Orthogonal Bundle 434 Repressor (Amino-terminal Domain) Signal recognition particle, SRP54 subunit, M-domain 1hq1A00
2PXBA 2PXKA 5GAGi 2PXQA 3LQXA 2XXAA 5GAHi 3KL4A 2FFHA 2PXEA 2V3CC 1MFQC 2PXLA 2PXVA 3NDBB 1QB2A 2PXUA 3DM5A 2JQEA 2PXDA 1HQ1A 1DULA 1QZXA 2PXFA 2PXPA 2PXTA
chains in the Genus database with same CATH superfamily
4YG7B 3BS3A 2PPXA 4X4FA 3SCFA 3OQNA 3H5TA 2LYLA 2ICTA 3A9ZA 4O8BA 1XWRA 1R69A 2MQKA 3TELA 1ZZBA 4YG1A 2LLVA 2PUDA 3CLCA 4I8TA 1QQAA 1SQ8A 1JWLA 2XJ3A 2IVGA 2HFZA 1CJGA 2H8RA 1DULA 2AXUA 1WH8A 2HCSA 1X57A 1JH9A 4YARA 3CECA 4EK9A 4IA8A 3NZLA 4Z59A 1ZS4A 4ER6A 2V3CC 1MFQC 5JUWA 4EQZA 4X4EA 2XXPA 4MCTA 1NEQA 2AUWA 3GBFA 3VWSA 1RPEL 4JCYA 2LLWA 4FBIA 3F51A 4GHJA 5DTQA 1YSEA 3UWPA 1BDIA 4PU3C 3EUSA 2PXLA 3CROL 1QB2A 1ZZ8A 1ZZ9A 3GZCA 3A9XA 1QP7A 2WIUB 1UXCA 3A9YA 1RZSA 2BNMA 2XI8A 2EF8A 2LYJA 4OB4A 1AU7A 4PU4C 3GN5B 2KEIA 2O4AA 3DM5A 2FJRA 4X4HA 3JXBC 3QWGA 1ADRA 2IVBA 3GUUA 3D1NI 3BDNA 2J7WA 4FN3A 3F52A 1ZZCA 1LMB3 4EKGA 2GZUA 1VPWA 1JFSA 2VEOA 5DTMA 3LFPA 2JCGA 1RZRD 3S8QA 4EKIA 3KJXA 1L1MA 1ZUGA 2OFYA 1LCCA 4Z5CA 1DWKA 2GRLA 3OP9A 3ME5A 5DRYA 2JVLA 4Z58A 3R1FA 2OR1L 1QP4A 2KEKA 3QOWA 2AW6A 1QQBA 2HCNA 2MEZA 3FYMA 5DRTA 4EZIA 2PUFA 1ZVVA 2KEJA 3TFLA 1RIOA 1NW3A 3ZHIA 4YG4A 2M4HA 3JXCL 3DNVB 2PUEA 4J1WA 1NERA 2PXVA 3QOXA 5DTRA 2BNNA 3QFIA 1PRUA 4X4BA 4OBMA 1HQ1A 4I6TA 3OKZA 1BDHA 4Y42A 2ODRD 2IV1A 1HF0A 1WIZA 2PXBA 2PXKA 1ZZ7A 3VK0A 2PE5A 1ZPQA 3F6WA 1EFAA 2MXDA 3G0TA 1E3OC 3PXPA 4Q2JA 2B5AA 2O49A 4DE8A 2D5VA 1PNRA 3HZIB 3L1PA 4X4GA 2CSFA 4JQDA 3RZZA 3ZKCA 3BD1A 3GZDC 2PXTA 5DSXA 1O4XA 3LQXA 1LQCA 3KZ3A 3KXAA 4WVLA 1Y9QA 2LCVA 4Z5DA 4IWRA 2LYSA 3OQMA 4ER3A 4X4CA 3QQ6A 4HRAA 3UFDA 4PU7A 2PXPA 1RZRA 1B0NA 2PUGA 1X2LA 3ZHMA 2LNMA 4J1XA 3KL4A 4PU8A 2ICPA 1UTXA 4I6RA 2GRMA 3NXHA 2PUCA 3MEJA 4IVZA 4DE9A 2R63A 4JCXA 4NDWA 3JXDL 2L1PA 2PUAA 1LCDA 2J7UA 1PRAA 4Z5HA 2BJCA 1GT0C 3GN5A 4ER7A 1U2ZA 1PERL 1ZAYA 2XXQA 1DW9A 4I6UA 1WH6A 2XIUA 1QPZA 3QF3A 3B7HA 3OMTA 3SR4A 2L8NA 1S7EA 2LYPA 1ZZ6A 2WUSR 2BNOA 1WETA 2XCJA 2PXFA 2EBYA 3TEPA 2AXZA 3FMYA 4F8DA 2XXAA 3LISA 1JFTA 2A6CA 2FFHA 3ZPXA 2PXEA 2O38A 4MCXA 3SCGA 2XSDC 3NDBB 3GZDA 1R63A 2PXDA 3U3WA 1CQTA 1PRVA 2AXVA 2PXQA 5K98B 1OCTC 2KZ8A 3SX0A 4X4IA 4GQMA 3OWQA 3QYXA 2L49A 2JQEA 2IVQA 1QZXA 4YBAA 2PUBA 3G5GA 3OQOA 3R09A 4ER5A 1POUA 1OSLA 3MLFA 2EWTA 2IU7A 2AWIA 3M9LA 3NROA 2PXUA 1QP0A 5DT2A 5A7LA 2CROA 2LYKA 2KPJA 5GAGi 3O9XA 5GAHi 2R1JL 4X4DA 2IUOA 2HINA 1LLIA 1IC8A 3TRBA 2LYRA 3IVPA 3SCHA 3FYAA 2YBDA 2LYQA 3PE5A 1Y7YA 2HSGA 4ER0A 1UXDA 2PIJA 3G7DA
chains in the Genus database with same CATH topology
2PXBA 2PXKA 5GAGi 2PXQA 3LQXA 2XXAA 5GAHi 3KL4A 2FFHA 2PXEA 2V3CC 1MFQC 2PXLA 2PXVA 3NDBB 1QB2A 2PXUA 3DM5A 2JQEA 2PXDA 1HQ1A 1DULA 1QZXA 2PXFA 2PXPA 2PXTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PXB A;  2PXK A;  5GAG i;  2PXQ A;  3LQX A;  2XXA A;  5GAH i;  3KL4 A;  2FFH A;  2PXE A;  2V3C C;  1MFQ C;  2PXL A;  2PXV A;  3NDB B;  1QB2 A;  2PXU A;  3DM5 A;  2JQE A;  2PXD A;  1HQ1 A;  1DUL A;  1QZX A;  2PXF A;  2PXP A;  2PXT A; 
#chains in the Genus database with same CATH topology
 4YG7 B;  3BS3 A;  2PPX A;  4X4F A;  3SCF A;  3OQN A;  3H5T A;  2LYL A;  2ICT A;  3A9Z A;  4O8B A;  1XWR A;  1R69 A;  2MQK A;  3TEL A;  1ZZB A;  4YG1 A;  2LLV A;  2PUD A;  3CLC A;  4I8T A;  1QQA A;  1SQ8 A;  1JWL A;  2XJ3 A;  2IVG A;  2HFZ A;  1CJG A;  2H8R A;  1DUL A;  2AXU A;  1WH8 A;  2HCS A;  1X57 A;  1JH9 A;  4YAR A;  3CEC A;  4EK9 A;  4IA8 A;  3NZL A;  4Z59 A;  1ZS4 A;  4ER6 A;  2V3C C;  1MFQ C;  5JUW A;  4EQZ A;  4X4E A;  2XXP A;  4MCT A;  1NEQ A;  2AUW A;  3GBF A;  3VWS A;  1RPE L;  4JCY A;  2LLW A;  4FBI A;  3F51 A;  4GHJ A;  5DTQ A;  1YSE A;  3UWP A;  1BDI A;  4PU3 C;  3EUS A;  2PXL A;  3CRO L;  1QB2 A;  1ZZ8 A;  1ZZ9 A;  3GZC A;  3A9X A;  1QP7 A;  2WIU B;  1UXC A;  3A9Y A;  1RZS A;  2BNM A;  2XI8 A;  2EF8 A;  2LYJ A;  4OB4 A;  1AU7 A;  4PU4 C;  3GN5 B;  2KEI A;  2O4A A;  3DM5 A;  2FJR A;  4X4H A;  3JXB C;  3QWG A;  1ADR A;  2IVB A;  3GUU A;  3D1N I;  3BDN A;  2J7W A;  4FN3 A;  3F52 A;  1ZZC A;  1LMB 3;  4EKG A;  2GZU A;  1VPW A;  1JFS A;  2VEO A;  5DTM A;  3LFP A;  2JCG A;  1RZR D;  3S8Q A;  4EKI A;  3KJX A;  1L1M A;  1ZUG A;  2OFY A;  1LCC A;  4Z5C A;  1DWK A;  2GRL A;  3OP9 A;  3ME5 A;  5DRY A;  2JVL A;  4Z58 A;  3R1F A;  2OR1 L;  1QP4 A;  2KEK A;  3QOW A;  2AW6 A;  1QQB A;  2HCN A;  2MEZ A;  3FYM A;  5DRT A;  4EZI A;  2PUF A;  1ZVV A;  2KEJ A;  3TFL A;  1RIO A;  1NW3 A;  3ZHI A;  4YG4 A;  2M4H A;  3JXC L;  3DNV B;  2PUE A;  4J1W A;  1NER A;  2PXV A;  3QOX A;  5DTR A;  2BNN A;  3QFI A;  1PRU A;  4X4B A;  4OBM A;  1HQ1 A;  4I6T A;  3OKZ A;  1BDH A;  4Y42 A;  2ODR D;  2IV1 A;  1HF0 A;  1WIZ A;  2PXB A;  2PXK A;  1ZZ7 A;  3VK0 A;  2PE5 A;  1ZPQ A;  3F6W A;  1EFA A;  2MXD A;  3G0T A;  1E3O C;  3PXP A;  4Q2J A;  2B5A A;  2O49 A;  4DE8 A;  2D5V A;  1PNR A;  3HZI B;  3L1P A;  4X4G A;  2CSF A;  4JQD A;  3RZZ A;  3ZKC A;  3BD1 A;  3GZD C;  2PXT A;  5DSX A;  1O4X A;  3LQX A;  1LQC A;  3KZ3 A;  3KXA A;  4WVL A;  1Y9Q A;  2LCV A;  4Z5D A;  4IWR A;  2LYS A;  3OQM A;  4ER3 A;  4X4C A;  3QQ6 A;  4HRA A;  3UFD A;  4PU7 A;  2PXP A;  1RZR A;  1B0N A;  2PUG A;  1X2L A;  3ZHM A;  2LNM A;  4J1X A;  3KL4 A;  4PU8 A;  2ICP A;  1UTX A;  4I6R A;  2GRM A;  3NXH A;  2PUC A;  3MEJ A;  4IVZ A;  4DE9 A;  2R63 A;  4JCX A;  4NDW A;  3JXD L;  2L1P A;  2PUA A;  1LCD A;  2J7U A;  1PRA A;  4Z5H A;  2BJC A;  1GT0 C;  3GN5 A;  4ER7 A;  1U2Z A;  1PER L;  1ZAY A;  2XXQ A;  1DW9 A;  4I6U A;  1WH6 A;  2XIU A;  1QPZ A;  3QF3 A;  3B7H A;  3OMT A;  3SR4 A;  2L8N A;  1S7E A;  2LYP A;  1ZZ6 A;  2WUS R;  2BNO A;  1WET A;  2XCJ A;  2PXF A;  2EBY A;  3TEP A;  2AXZ A;  3FMY A;  4F8D A;  2XXA A;  3LIS A;  1JFT A;  2A6C A;  2FFH A;  3ZPX A;  2PXE A;  2O38 A;  4MCX A;  3SCG A;  2XSD C;  3NDB B;  3GZD A;  1R63 A;  2PXD A;  3U3W A;  1CQT A;  1PRV A;  2AXV A;  2PXQ A;  5K98 B;  1OCT C;  2KZ8 A;  3SX0 A;  4X4I A;  4GQM A;  3OWQ A;  3QYX A;  2L49 A;  2JQE A;  2IVQ A;  1QZX A;  4YBA A;  2PUB A;  3G5G A;  3OQO A;  3R09 A;  4ER5 A;  1POU A;  1OSL A;  3MLF A;  2EWT A;  2IU7 A;  2AWI A;  3M9L A;  3NRO A;  2PXU A;  1QP0 A;  5DT2 A;  5A7L A;  2CRO A;  2LYK A;  2KPJ A;  5GAG i;  3O9X A;  5GAH i;  2R1J L;  4X4D A;  2IUO A;  2HIN A;  1LLI A;  1IC8 A;  3TRB A;  2LYR A;  3IVP A;  3SCH A;  3FYA A;  2YBD A;  2LYQ A;  3PE5 A;  1Y7Y A;  2HSG A;  4ER0 A;  1UXD A;  2PIJ A;  3G7D A; 
#chains in the Genus database with same CATH homology
 2PXB A;  2PXK A;  5GAG i;  2PXQ A;  3LQX A;  2XXA A;  5GAH i;  3KL4 A;  2FFH A;  2PXE A;  2V3C C;  1MFQ C;  2PXL A;  2PXV A;  3NDB B;  1QB2 A;  2PXU A;  3DM5 A;  2JQE A;  2PXD A;  1HQ1 A;  1DUL A;  1QZX A;  2PXF A;  2PXP A;  2PXT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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