2HCSA

Crystal structure of rna dependant rna polymerase domain of west nile virus
Total Genus 175
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
570
structure length
487
Chain Sequence
LVNGVVRLLSKPWDTIDTKAPEPPEGVKYVLNETTNWLWAFLAREKRPRMCSREEFIRKVNSNAAQWRSAREAVEDPKFWEMVDEEREAHLRGECHTCSRAIWFMWLGARFLEFEALGFLNEDHWLGRKNSGGGVEGLGLQKLGYILREVGTRPGGRIYADDTAGWDTRITRADLENEAKVLELLDGEHRRLARAIIELTYRGSGQVVTYALNTFTNLAVQLVRMMEGEGVIGPDDVEKLTKGKGPKVRTWLSENGEERLSRMAVSGDDCVVKPLDDRFATSLHFLNAMSKVRKDIQEWKPSTGWYDWQQVPFCSNHFTELIMKDGRTLVTPCRGQDELVGRARISPNVRDTACLAKSYAQMWLLLYFHRRDLRLMANAICSAVPVNWVPTGRTTWSIHAGGEWMTTEDMLEVWNRVWIEENEWMEDKTPVEKWSDVPYSGKREDIWCGSLIGTRARATWAENIQVAINQVRSIIGDEKYVDYMSSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
pubmed doi rcsb
molecule tags Transferase
source organism Kunjin virus
molecule keywords RNA-directed RNA polymerase (NS5)
total genus 175
structure length 487
sequence length 570
ec nomenclature ec 2.1.1.56: mRNA (guanine-N(7)-)-methyltransferase.
pdb deposition date 2006-06-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.260.90 Mainly Alpha Orthogonal Bundle 434 Repressor (Amino-terminal Domain) 434 Repressor (Amino-terminal Domain) 2hcsA03
3VWSA 2HCNA 2HCSA 2HFZA 2J7UA 2J7WA
chains in the Genus database with same CATH superfamily
2EF8A 1XWRA 2IVGA 1CJGA 3MLFA 5DRYA 3SCFA 2PXPA 3PXPA 3A9XA 3TFLA 5DRTA 2LYRA 3D1NI 3OP9A 2YBDA 4ER3A 1WETA 1LLIA 1ZZ6A 1NEQA 1UXDA 2PPXA 4Z5CA 2V3CC 4YG7B 5DTMA 1POUA 3TRBA 2JVLA 4JCYA 2PUGA 2JCGA 2LYKA 4YG1A 1ZUGA 3TELA 1QQBA 3PE5A 1QPZA 1LQCA 4X4BA 1LCCA 3S8QA 4EKGA 2LLVA 2VEOA 3RZZA 1R69A 3IVPA 3JXBC 1NW3A 3M9LA 2IUOA 1ZVVA 2HCNA 2HSGA 2XI8A 3BDNA 4FN3A 3GZCA 1PRAA 4PU8A 2AUWA 2R63A 2WIUB 4OB4A 5GAGi 2PUAA 2HFZA 3OQNA 3VWSA 1B0NA 2LYPA 3LFPA 2PXEA 2OR1L 3NZLA 1WH8A 1EFAA 1WH6A 4Z58A 1ZZ8A 1ZPQA 4PU3C 3O9XA 1NERA 3GZDA 1ZZ7A 2KEIA 3OQOA 1PRUA 3QYXA 2O49A 2LYQA 3EUSA 3OMTA 4EQZA 3KJXA 3TEPA 3SCGA 2PIJA 1SQ8A 5K98B 4EKIA 2XJ3A 2EBYA 1Y7YA 2PUDA 2CSFA 3F52A 3GN5B 3QWGA 1LCDA 3R1FA 2PXVA 1RZSA 2PXUA 2AWIA 3NDBB 1RIOA 1L1MA 3H5TA 3G5GA 2IU7A 4GQMA 2PE5A 3OKZA 1DW9A 1QZXA 1ZZBA 2BJCA 2PXQA 1GT0C 4Y42A 3OWQA 3FYAA 1RZRA 1UTXA 2MEZA 4YARA 2XIUA 3ZPXA 2IVBA 2PUEA 3ZHIA 2AXVA 1PRVA 2LYSA 2AW6A 4I6TA 5DT2A 2KEKA 1E3OC 2PXTA 4ER6A 2L8NA 2O38A 2KZ8A 3F51A 3GZDC 1DWKA 2R1JL 2BNOA 1R63A 1BDIA 1QB2A 1JH9A 3LQXA 2OFYA 3B7HA 2PXKA 1ZZCA 2LLWA 2CROA 1X2LA 5A7LA 1CQTA 3F6WA 3BD1A 3ZKCA 2ICPA 3U3WA 3R09A 3ZHMA 3NROA 4Z5DA 4X4FA 2L49A 2PXBA 2L1PA 1ZZ9A 2GRMA 1OSLA 2IVQA 1AU7A 1PNRA 3A9YA 2B5AA 3QQ6A 4PU4C 2LYJA 3JXCL 2PXLA 2XSDC 4IVZA 2FJRA 1BDHA 5DTQA 2H8RA 3FMYA 3DNVB 3G0TA 4DE8A 2XCJA 4IWRA 1O4XA 4X4HA 3CECA 3GBFA 4X4IA 2M4HA 2KPJA 4HRAA 1IC8A 2XXAA 1ZAYA 4NDWA 4Z5HA 2ODRD 4Z59A 4ER5A 4OBMA 2PUFA 3KXAA 4I6RA 3L1PA 2PUCA 4Q2JA 3ME5A 4EK9A 5GAHi 3KZ3A 2BNNA 3SR4A 2FFHA 3QOWA 4MCXA 2GRLA 4X4GA 1Y9QA 1WIZA 4GHJA 1JFSA 2XXPA 4DE9A 1DULA 2MXDA 4J1XA 1S7EA 3QFIA 3UWPA 1ZS4A 4FBIA 4PU7A 1QP0A 1OCTC 5DSXA 1RPEL 2HINA 2JQEA 4IA8A 3MEJA 2J7UA 2AXZA 1QP7A 3NXHA 1U2ZA 2LNMA 1QQAA 4I8TA 3SX0A 2A6CA 2O4AA 3BS3A 2ICTA 1HF0A 2AXUA 5JUWA 3A9ZA 4JCXA 4ER0A 2BNMA 2LCVA 1X57A 3GUUA 1JWLA 3FYMA 3VK0A 4YBAA 2EWTA 2D5VA 2KEJA 4YG4A 1VPWA 3KL4A 3SCHA 4O8BA 3GN5A 4J1WA 4ER7A 3CROL 1LMB3 4F8DA 2J7WA 3DM5A 1QP4A 3QF3A 2WUSR 3JXDL 4JQDA 3OQMA 1UXCA 4X4EA 1JFTA 2HCSA 2GZUA 3CLCA 2MQKA 4I6UA 3G7DA 3QOXA 4X4DA 2PUBA 2LYLA 2PXDA 3UFDA 2IV1A 5DTRA 1ADRA 4EZIA 1MFQC 1RZRD 4X4CA 3LISA 4WVLA 1PERL 2XXQA 2PXFA 3HZIB 1HQ1A 1YSEA 4MCTA
chains in the Genus database with same CATH topology
5DTMA 3GZDC 2HFZA 2VEOA 5JUWA 3R09A 3A9ZA 4Q2JA 5DRYA 4EQZA 3QFIA 3A9YA 5DTRA 3UWPA 4ER0A 4EZIA 3NROA 3VWSA 3ZPXA 2M4HA 3SR4A 4HRAA 1NW3A 4WVLA 2XXQA 3QOWA 3M9LA 3GUUA 5DSXA 3A9XA 3TEPA 3NZLA 3TELA 2HCNA 2HCSA 3TFLA 3OKZA 2ODRD 2L1PA 2LLWA 3MEJA 5DT2A 2J7UA 5DRTA 3PE5A 4EKIA 4EK9A 3GZCA 5DTQA 4ER6A 4ER5A 2YBDA 4OBMA 3NXHA 3GZDA 1U2ZA 3G0TA 2LNMA 2XXPA 4EKGA 4DE8A 4DE9A 4ER7A 4ER3A 3OWQA 3SX0A 2MXDA 2LLVA 3QOXA 3ME5A 2J7WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VWS A;  2HCN A;  2HCS A;  2HFZ A;  2J7U A;  2J7W A; 
#chains in the Genus database with same CATH topology
 2EF8 A;  1XWR A;  2IVG A;  1CJG A;  3MLF A;  5DRY A;  3SCF A;  2PXP A;  3PXP A;  3A9X A;  3TFL A;  5DRT A;  2LYR A;  3D1N I;  3OP9 A;  2YBD A;  4ER3 A;  1WET A;  1LLI A;  1ZZ6 A;  1NEQ A;  1UXD A;  2PPX A;  4Z5C A;  2V3C C;  4YG7 B;  5DTM A;  1POU A;  3TRB A;  2JVL A;  4JCY A;  2PUG A;  2JCG A;  2LYK A;  4YG1 A;  1ZUG A;  3TEL A;  1QQB A;  3PE5 A;  1QPZ A;  1LQC A;  4X4B A;  1LCC A;  3S8Q A;  4EKG A;  2LLV A;  2VEO A;  3RZZ A;  1R69 A;  3IVP A;  3JXB C;  1NW3 A;  3M9L A;  2IUO A;  1ZVV A;  2HCN A;  2HSG A;  2XI8 A;  3BDN A;  4FN3 A;  3GZC A;  1PRA A;  4PU8 A;  2AUW A;  2R63 A;  2WIU B;  4OB4 A;  5GAG i;  2PUA A;  2HFZ A;  3OQN A;  3VWS A;  1B0N A;  2LYP A;  3LFP A;  2PXE A;  2OR1 L;  3NZL A;  1WH8 A;  1EFA A;  1WH6 A;  4Z58 A;  1ZZ8 A;  1ZPQ A;  4PU3 C;  3O9X A;  1NER A;  3GZD A;  1ZZ7 A;  2KEI A;  3OQO A;  1PRU A;  3QYX A;  2O49 A;  2LYQ A;  3EUS A;  3OMT A;  4EQZ A;  3KJX A;  3TEP A;  3SCG A;  2PIJ A;  1SQ8 A;  5K98 B;  4EKI A;  2XJ3 A;  2EBY A;  1Y7Y A;  2PUD A;  2CSF A;  3F52 A;  3GN5 B;  3QWG A;  1LCD A;  3R1F A;  2PXV A;  1RZS A;  2PXU A;  2AWI A;  3NDB B;  1RIO A;  1L1M A;  3H5T A;  3G5G A;  2IU7 A;  4GQM A;  2PE5 A;  3OKZ A;  1DW9 A;  1QZX A;  1ZZB A;  2BJC A;  2PXQ A;  1GT0 C;  4Y42 A;  3OWQ A;  3FYA A;  1RZR A;  1UTX A;  2MEZ A;  4YAR A;  2XIU A;  3ZPX A;  2IVB A;  2PUE A;  3ZHI A;  2AXV A;  1PRV A;  2LYS A;  2AW6 A;  4I6T A;  5DT2 A;  2KEK A;  1E3O C;  2PXT A;  4ER6 A;  2L8N A;  2O38 A;  2KZ8 A;  3F51 A;  3GZD C;  1DWK A;  2R1J L;  2BNO A;  1R63 A;  1BDI A;  1QB2 A;  1JH9 A;  3LQX A;  2OFY A;  3B7H A;  2PXK A;  1ZZC A;  2LLW A;  2CRO A;  1X2L A;  5A7L A;  1CQT A;  3F6W A;  3BD1 A;  3ZKC A;  2ICP A;  3U3W A;  3R09 A;  3ZHM A;  3NRO A;  4Z5D A;  4X4F A;  2L49 A;  2PXB A;  2L1P A;  1ZZ9 A;  2GRM A;  1OSL A;  2IVQ A;  1AU7 A;  1PNR A;  3A9Y A;  2B5A A;  3QQ6 A;  4PU4 C;  2LYJ A;  3JXC L;  2PXL A;  2XSD C;  4IVZ A;  2FJR A;  1BDH A;  5DTQ A;  2H8R A;  3FMY A;  3DNV B;  3G0T A;  4DE8 A;  2XCJ A;  4IWR A;  1O4X A;  4X4H A;  3CEC A;  3GBF A;  4X4I A;  2M4H A;  2KPJ A;  4HRA A;  1IC8 A;  2XXA A;  1ZAY A;  4NDW A;  4Z5H A;  2ODR D;  4Z59 A;  4ER5 A;  4OBM A;  2PUF A;  3KXA A;  4I6R A;  3L1P A;  2PUC A;  4Q2J A;  3ME5 A;  4EK9 A;  5GAH i;  3KZ3 A;  2BNN A;  3SR4 A;  2FFH A;  3QOW A;  4MCX A;  2GRL A;  4X4G A;  1Y9Q A;  1WIZ A;  4GHJ A;  1JFS A;  2XXP A;  4DE9 A;  1DUL A;  2MXD A;  4J1X A;  1S7E A;  3QFI A;  3UWP A;  1ZS4 A;  4FBI A;  4PU7 A;  1QP0 A;  1OCT C;  5DSX A;  1RPE L;  2HIN A;  2JQE A;  4IA8 A;  3MEJ A;  2J7U A;  2AXZ A;  1QP7 A;  3NXH A;  1U2Z A;  2LNM A;  1QQA A;  4I8T A;  3SX0 A;  2A6C A;  2O4A A;  3BS3 A;  2ICT A;  1HF0 A;  2AXU A;  5JUW A;  3A9Z A;  4JCX A;  4ER0 A;  2BNM A;  2LCV A;  1X57 A;  3GUU A;  1JWL A;  3FYM A;  3VK0 A;  4YBA A;  2EWT A;  2D5V A;  2KEJ A;  4YG4 A;  1VPW A;  3KL4 A;  3SCH A;  4O8B A;  3GN5 A;  4J1W A;  4ER7 A;  3CRO L;  1LMB 3;  4F8D A;  2J7W A;  3DM5 A;  1QP4 A;  3QF3 A;  2WUS R;  3JXD L;  4JQD A;  3OQM A;  1UXC A;  4X4E A;  1JFT A;  2HCS A;  2GZU A;  3CLC A;  2MQK A;  4I6U A;  3G7D A;  3QOX A;  4X4D A;  2PUB A;  2LYL A;  2PXD A;  3UFD A;  2IV1 A;  5DTR A;  1ADR A;  4EZI A;  1MFQ C;  1RZR D;  4X4C A;  3LIS A;  4WVL A;  1PER L;  2XXQ A;  2PXF A;  3HZI B;  1HQ1 A;  1YSE A;  4MCT A; 
#chains in the Genus database with same CATH homology
 5DTM A;  3GZD C;  2HFZ A;  2VEO A;  5JUW A;  3R09 A;  3A9Z A;  4Q2J A;  5DRY A;  4EQZ A;  3QFI A;  3A9Y A;  5DTR A;  3UWP A;  4ER0 A;  4EZI A;  3NRO A;  3VWS A;  3ZPX A;  2M4H A;  3SR4 A;  4HRA A;  1NW3 A;  4WVL A;  2XXQ A;  3QOW A;  3M9L A;  3GUU A;  5DSX A;  3A9X A;  3TEP A;  3NZL A;  3TEL A;  2HCN A;  2HCS A;  3TFL A;  3OKZ A;  2ODR D;  2L1P A;  2LLW A;  3MEJ A;  5DT2 A;  2J7U A;  5DRT A;  3PE5 A;  4EKI A;  4EK9 A;  3GZC A;  5DTQ A;  4ER6 A;  4ER5 A;  2YBD A;  4OBM A;  3NXH A;  3GZD A;  1U2Z A;  3G0T A;  2LNM A;  2XXP A;  4EKG A;  4DE8 A;  4DE9 A;  4ER7 A;  4ER3 A;  3OWQ A;  3SX0 A;  2MXD A;  2LLV A;  3QOX A;  3ME5 A;  2J7W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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