1MFQC

Crystal structure analysis of a ternary s-domain complex of human signal recognition particle
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
116
structure length
108
Chain Sequence
KHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMVKKMGGIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Induced structural changes of 7SL RNA during the assembly of human signal recognition particle
pubmed doi rcsb
molecule tags Signaling protein/rna
source organism Homo sapiens
molecule keywords 7S RNA of human SRP
total genus 32
structure length 108
sequence length 116
ec nomenclature
pdb deposition date 2002-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF02978 SRP_SPB Signal peptide binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.260.30 Mainly Alpha Orthogonal Bundle 434 Repressor (Amino-terminal Domain) Signal recognition particle, SRP54 subunit, M-domain 1mfqC00
3KL4A 2FFHA 2PXLA 2PXDA 2PXKA 1QB2A 2PXTA 3LQXA 2PXPA 1QZXA 2PXBA 2XXAA 3DM5A 2PXQA 1HQ1A 3NDBB 5GAHi 2PXFA 2JQEA 1DULA 2V3CC 2PXVA 5GAGi 1MFQC 2PXUA 2PXEA
chains in the Genus database with same CATH superfamily
3KL4A 4PU8A 1RZRA 4EZIA 2J7WA 3QQ6A 2PXPA 5K98B 3LFPA 2AXUA 4MCXA 2XI8A 4ER7A 1NEQA 1OCTC 2HCSA 3GZDC 3JXBC 4X4FA 3QWGA 2JVLA 4PU7A 1CJGA 3PXPA 3MLFA 2IVQA 3SX0A 3OP9A 5A7LA 2LYKA 3F52A 2PUGA 4I8TA 2GZUA 3PE5A 3TRBA 1ADRA 2B5AA 3KJXA 2ICTA 1VPWA 4X4EA 3F6WA 1DULA 3GBFA 4MCTA 2XXQA 3O9XA 2M4HA 3CROL 2HINA 2LYPA 2XXAA 5DTQA 3NZLA 4Q2JA 2PXQA 2GRMA 2IUOA 1IC8A 4PU4C 2FJRA 3ZHMA 3OQMA 2O49A 1PNRA 1LMB3 3TELA 2XXPA 1ZZ8A 3LQXA 4OBMA 1LCCA 1DWKA 2R63A 3M9LA 4Y42A 4X4BA 3FYMA 3TFLA 2O4AA 2LYLA 1LQCA 5DSXA 1RZRD 3BDNA 2PUFA 1QB2A 4ER5A 3MEJA 1UXDA 3CLCA 1RPEL 3RZZA 2PUAA 1UTXA 2XCJA 2PXBA 3A9YA 4Z59A 2XSDC 1ZVVA 2BJCA 2YBDA 3NROA 3GN5A 2PXFA 1R63A 3OQOA 3OMTA 3SCGA 2ODRD 4X4GA 1AU7A 2PXUA 1NERA 3GZCA 4YG7B 3OWQA 2XIUA 1QP4A 4ER6A 2EWTA 4O8BA 4X4CA 3IVPA 4Z58A 3JXCL 4IWRA 1Y7YA 2HSGA 4JCXA 2KPJA 3QOXA 4IVZA 1WH6A 1ZS4A 4YG4A 4YG1A 1QZXA 3BD1A 3UFDA 4Z5DA 5DRYA 4FBIA 1ZZ6A 2EBYA 2LNMA 4EK9A 2L1PA 3NXHA 2KEIA 1HQ1A 2JQEA 4YBAA 5DTMA 3L1PA 1ZZCA 3JXDL 3D1NI 1E3OC 1QQBA 1JWLA 3G5GA 3U3WA 3F51A 1ZZ9A 4JCYA 2AUWA 2ICPA 1PRVA 2PUCA 1JFSA 5DRTA 1ZPQA 2AWIA 3HZIB 1PRUA 3SCFA 3BS3A 4Z5HA 1QQAA 2MQKA 4ER3A 2VEOA 1WETA 3ZPXA 1HF0A 3VWSA 2AXZA 2KEKA 3S8QA 3NDBB 3G0TA 1R69A 2V3CC 1MFQC 5DTRA 3ZKCA 1QP0A 2IVGA 1X57A 2PXLA 1UXCA 2LLWA 2LLVA 2XJ3A 3R1FA 1EFAA 2BNMA 1ZAYA 4J1WA 3OQNA 3QOWA 2MXDA 2PE5A 2LYSA 1LCDA 2WUSR 3DNVB 1RZSA 4NDWA 2EF8A 3GN5B 2D5VA 2KZ8A 4EKGA 3A9XA 2BNNA 2CSFA 1OSLA 1NW3A 2LYRA 4GHJA 1B0NA 2PUBA 5GAHi 4YARA 1XWRA 2JCGA 2HFZA 2GRLA 2IV1A 2PXKA 3GZDA 4J1XA 4Z5CA 4PU3C 5JUWA 2WIUB 3ME5A 2MEZA 1ZZ7A 2L49A 3FYAA 3LISA 2J7UA 2PXEA 2AXVA 2PXDA 3G7DA 4EKIA 2KEJA 1BDHA 2PUDA 2PXTA 3UWPA 3B7HA 4GQMA 2L8NA 4ER0A 1YSEA 2O38A 3DM5A 2BNOA 3R09A 2PIJA 1SQ8A 1JFTA 1JH9A 4I6RA 1PRAA 2PPXA 1PERL 5GAGi 1ZUGA 2LCVA 3QFIA 3EUSA 2A6CA 1DW9A 3QYXA 4EQZA 3KZ3A 3FMYA 3VK0A 3TEPA 3SCHA 4HRAA 2HCNA 3QF3A 5DT2A 4F8DA 4DE8A 1ZZBA 2LYQA 4JQDA 2OR1L 1BDIA 1QPZA 3A9ZA 1L1MA 1O4XA 1WH8A 1GT0C 3OKZA 3H5TA 2OFYA 2R1JL 4IA8A 4I6TA 3KXAA 1POUA 2H8RA 1Y9QA 1S7EA 3CECA 4X4HA 1QP7A 2FFHA 1LLIA 2CROA 4WVLA 1U2ZA 4X4DA 2IVBA 4FN3A 2LYJA 1WIZA 2PUEA 4X4IA 1RIOA 4I6UA 3GUUA 1X2LA 1CQTA 2AW6A 2IU7A 3SR4A 3ZHIA 2PXVA 4DE9A 4OB4A
chains in the Genus database with same CATH topology
3KL4A 2FFHA 2PXLA 2PXDA 2PXKA 1QB2A 2PXTA 3LQXA 2PXPA 1QZXA 2PXBA 2XXAA 3DM5A 2PXQA 1HQ1A 3NDBB 5GAHi 2PXFA 2JQEA 1DULA 2V3CC 2PXVA 5GAGi 1MFQC 2PXUA 2PXEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KL4 A;  2FFH A;  2PXL A;  2PXD A;  2PXK A;  1QB2 A;  2PXT A;  3LQX A;  2PXP A;  1QZX A;  2PXB A;  2XXA A;  3DM5 A;  2PXQ A;  1HQ1 A;  3NDB B;  5GAH i;  2PXF A;  2JQE A;  1DUL A;  2V3C C;  2PXV A;  5GAG i;  1MFQ C;  2PXU A;  2PXE A; 
#chains in the Genus database with same CATH topology
 3KL4 A;  4PU8 A;  1RZR A;  4EZI A;  2J7W A;  3QQ6 A;  2PXP A;  5K98 B;  3LFP A;  2AXU A;  4MCX A;  2XI8 A;  4ER7 A;  1NEQ A;  1OCT C;  2HCS A;  3GZD C;  3JXB C;  4X4F A;  3QWG A;  2JVL A;  4PU7 A;  1CJG A;  3PXP A;  3MLF A;  2IVQ A;  3SX0 A;  3OP9 A;  5A7L A;  2LYK A;  3F52 A;  2PUG A;  4I8T A;  2GZU A;  3PE5 A;  3TRB A;  1ADR A;  2B5A A;  3KJX A;  2ICT A;  1VPW A;  4X4E A;  3F6W A;  1DUL A;  3GBF A;  4MCT A;  2XXQ A;  3O9X A;  2M4H A;  3CRO L;  2HIN A;  2LYP A;  2XXA A;  5DTQ A;  3NZL A;  4Q2J A;  2PXQ A;  2GRM A;  2IUO A;  1IC8 A;  4PU4 C;  2FJR A;  3ZHM A;  3OQM A;  2O49 A;  1PNR A;  1LMB 3;  3TEL A;  2XXP A;  1ZZ8 A;  3LQX A;  4OBM A;  1LCC A;  1DWK A;  2R63 A;  3M9L A;  4Y42 A;  4X4B A;  3FYM A;  3TFL A;  2O4A A;  2LYL A;  1LQC A;  5DSX A;  1RZR D;  3BDN A;  2PUF A;  1QB2 A;  4ER5 A;  3MEJ A;  1UXD A;  3CLC A;  1RPE L;  3RZZ A;  2PUA A;  1UTX A;  2XCJ A;  2PXB A;  3A9Y A;  4Z59 A;  2XSD C;  1ZVV A;  2BJC A;  2YBD A;  3NRO A;  3GN5 A;  2PXF A;  1R63 A;  3OQO A;  3OMT A;  3SCG A;  2ODR D;  4X4G A;  1AU7 A;  2PXU A;  1NER A;  3GZC A;  4YG7 B;  3OWQ A;  2XIU A;  1QP4 A;  4ER6 A;  2EWT A;  4O8B A;  4X4C A;  3IVP A;  4Z58 A;  3JXC L;  4IWR A;  1Y7Y A;  2HSG A;  4JCX A;  2KPJ A;  3QOX A;  4IVZ A;  1WH6 A;  1ZS4 A;  4YG4 A;  4YG1 A;  1QZX A;  3BD1 A;  3UFD A;  4Z5D A;  5DRY A;  4FBI A;  1ZZ6 A;  2EBY A;  2LNM A;  4EK9 A;  2L1P A;  3NXH A;  2KEI A;  1HQ1 A;  2JQE A;  4YBA A;  5DTM A;  3L1P A;  1ZZC A;  3JXD L;  3D1N I;  1E3O C;  1QQB A;  1JWL A;  3G5G A;  3U3W A;  3F51 A;  1ZZ9 A;  4JCY A;  2AUW A;  2ICP A;  1PRV A;  2PUC A;  1JFS A;  5DRT A;  1ZPQ A;  2AWI A;  3HZI B;  1PRU A;  3SCF A;  3BS3 A;  4Z5H A;  1QQA A;  2MQK A;  4ER3 A;  2VEO A;  1WET A;  3ZPX A;  1HF0 A;  3VWS A;  2AXZ A;  2KEK A;  3S8Q A;  3NDB B;  3G0T A;  1R69 A;  2V3C C;  1MFQ C;  5DTR A;  3ZKC A;  1QP0 A;  2IVG A;  1X57 A;  2PXL A;  1UXC A;  2LLW A;  2LLV A;  2XJ3 A;  3R1F A;  1EFA A;  2BNM A;  1ZAY A;  4J1W A;  3OQN A;  3QOW A;  2MXD A;  2PE5 A;  2LYS A;  1LCD A;  2WUS R;  3DNV B;  1RZS A;  4NDW A;  2EF8 A;  3GN5 B;  2D5V A;  2KZ8 A;  4EKG A;  3A9X A;  2BNN A;  2CSF A;  1OSL A;  1NW3 A;  2LYR A;  4GHJ A;  1B0N A;  2PUB A;  5GAH i;  4YAR A;  1XWR A;  2JCG A;  2HFZ A;  2GRL A;  2IV1 A;  2PXK A;  3GZD A;  4J1X A;  4Z5C A;  4PU3 C;  5JUW A;  2WIU B;  3ME5 A;  2MEZ A;  1ZZ7 A;  2L49 A;  3FYA A;  3LIS A;  2J7U A;  2PXE A;  2AXV A;  2PXD A;  3G7D A;  4EKI A;  2KEJ A;  1BDH A;  2PUD A;  2PXT A;  3UWP A;  3B7H A;  4GQM A;  2L8N A;  4ER0 A;  1YSE A;  2O38 A;  3DM5 A;  2BNO A;  3R09 A;  2PIJ A;  1SQ8 A;  1JFT A;  1JH9 A;  4I6R A;  1PRA A;  2PPX A;  1PER L;  5GAG i;  1ZUG A;  2LCV A;  3QFI A;  3EUS A;  2A6C A;  1DW9 A;  3QYX A;  4EQZ A;  3KZ3 A;  3FMY A;  3VK0 A;  3TEP A;  3SCH A;  4HRA A;  2HCN A;  3QF3 A;  5DT2 A;  4F8D A;  4DE8 A;  1ZZB A;  2LYQ A;  4JQD A;  2OR1 L;  1BDI A;  1QPZ A;  3A9Z A;  1L1M A;  1O4X A;  1WH8 A;  1GT0 C;  3OKZ A;  3H5T A;  2OFY A;  2R1J L;  4IA8 A;  4I6T A;  3KXA A;  1POU A;  2H8R A;  1Y9Q A;  1S7E A;  3CEC A;  4X4H A;  1QP7 A;  2FFH A;  1LLI A;  2CRO A;  4WVL A;  1U2Z A;  4X4D A;  2IVB A;  4FN3 A;  2LYJ A;  1WIZ A;  2PUE A;  4X4I A;  1RIO A;  4I6U A;  3GUU A;  1X2L A;  1CQT A;  2AW6 A;  2IU7 A;  3SR4 A;  3ZHI A;  2PXV A;  4DE9 A;  4OB4 A; 
#chains in the Genus database with same CATH homology
 3KL4 A;  2FFH A;  2PXL A;  2PXD A;  2PXK A;  1QB2 A;  2PXT A;  3LQX A;  2PXP A;  1QZX A;  2PXB A;  2XXA A;  3DM5 A;  2PXQ A;  1HQ1 A;  3NDB B;  5GAH i;  2PXF A;  2JQE A;  1DUL A;  2V3C C;  2PXV A;  5GAG i;  1MFQ C;  2PXU A;  2PXE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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