1QB2A

Crystal structure of the conserved subdomain of human protein srp54m at 2.1a resolution: evidence for the mechanism of signal peptide binding
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
106
structure length
106
Chain Sequence
QFTLRDMYEQFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the conserved subdomain of human protein SRP54M at 2.1 A resolution: evidence for the mechanism of signal peptide binding.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords HUMAN SIGNAL RECOGNITION PARTICLE 54 KD PROTEIN
total genus 38
structure length 106
sequence length 106
chains with identical sequence B
ec nomenclature
pdb deposition date 1999-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02978 SRP_SPB Signal peptide binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.260.30 Mainly Alpha Orthogonal Bundle 434 Repressor (Amino-terminal Domain) Signal recognition particle, SRP54 subunit, M-domain 1qb2A00
2PXDA 5GAGi 2FFHA 2PXVA 3LQXA 2PXBA 2PXKA 2PXLA 3DM5A 5GAHi 2XXAA 2PXPA 1HQ1A 3KL4A 2PXEA 2JQEA 2PXQA 2PXFA 2V3CC 1MFQC 1DULA 3NDBB 1QZXA 1QB2A 2PXTA 2PXUA
chains in the Genus database with same CATH superfamily
3OWQA 5GAGi 2PUFA 2LYPA 3JXBC 2JVLA 1VPWA 2XI8A 4MCXA 2V3CC 3TFLA 2L8NA 2LYSA 2PUEA 1QZXA 1R69A 3H5TA 3SCFA 3F6WA 4X4EA 1LQCA 3G0TA 3KL4A 2JQEA 4Y42A 3VK0A 1ZVVA 2PUBA 1HF0A 1L1MA 3BDNA 1OSLA 3QF3A 1WIZA 1RZRD 4ER3A 3L1PA 2LCVA 1ZZ9A 3KXAA 3TELA 2H8RA 4EK9A 3QFIA 4Z5HA 3GUUA 1YSEA 2BJCA 3SCHA 3A9YA 4MCTA 2LNMA 2XCJA 2GRMA 3QQ6A 4X4FA 2BNOA 2LLVA 1LMB3 2AXVA 3CROL 1DULA 3GBFA 4YG4A 1BDHA 3U3WA 1ZUGA 1IC8A 4X4IA 2VEOA 2FFHA 2LYLA 3R1FA 3UFDA 4Z58A 2R63A 3MLFA 3NROA 2FJRA 1QP0A 2HCSA 2HSGA 2BNNA 2PUAA 2OR1L 3CECA 2J7WA 3ZHIA 3F52A 4YBAA 3JXDL 1UXCA 1PNRA 2YBDA 4F8DA 2LYJA 3KZ3A 3M9LA 2O38A 3GN5B 2XSDC 2IVQA 4ER6A 1DWKA 4NDWA 3KJXA 2LYKA 2PE5A 2M4HA 1PRUA 4I6UA 2KZ8A 3PE5A 5K98B 2MQKA 3GN5A 2R1JL 2PXQA 2IUOA 2KEKA 2EF8A 1QB2A 3A9XA 2PXUA 5DT2A 4O8BA 2CROA 2AW6A 2PXKA 5GAHi 2KEIA 2J7UA 3G7DA 1QQAA 4HRAA 2EBYA 4PU7A 3CLCA 2OFYA 2ICTA 1GT0C 3D1NI 4FBIA 4EKIA 2PUDA 2HCNA 1JWLA 2EWTA 2IU7A 1U2ZA 4Z59A 4PU3C 1NERA 3OQOA 4X4GA 1S7EA 4ER0A 4J1XA 2D5VA 1HQ1A 1POUA 1E3OC 3OMTA 1CQTA 1QPZA 5A7LA 1PERL 4ER7A 3ZPXA 3QYXA 2XJ3A 3UWPA 2L1PA 3HZIB 1OCTC 2PUCA 4JCYA 2O4AA 4PU4C 2LYQA 2KEJA 2XXAA 3QOWA 3FYMA 4I6TA 3G5GA 4X4DA 1RZSA 3IVPA 2AWIA 3SR4A 1LCCA 1JH9A 3LISA 4X4BA 3LQXA 3MEJA 1AU7A 4I6RA 4X4HA 1ZS4A 4DE8A 3GZCA 2IVBA 4YG7B 1ZPQA 1WETA 1ZAYA 3ME5A 2WUSR 1QQBA 4OB4A 3NDBB 1RPEL 1NW3A 1NEQA 3ZKCA 1RIOA 4Z5DA 3QWGA 3A9ZA 1PRAA 2PUGA 1ZZ7A 2LLWA 5DSXA 3NXHA 1ZZ8A 4DE9A 4FN3A 2XXPA 3R09A 2PXPA 1XWRA 1WH6A 1ZZCA 5JUWA 4EZIA 4PU8A 3F51A 3BS3A 3O9XA 3ZHMA 1ZZ6A 2A6CA 3OQNA 3DNVB 5DTRA 2O49A 4JQDA 2PXDA 3NZLA 3BD1A 4Z5CA 4OBMA 1X57A 2LYRA 4WVLA 2GZUA 5DRTA 3OP9A 2WIUB 4IA8A 4X4CA 2PXTA 1EFAA 1QP7A 4GQMA 2ICPA 4YARA 2AXUA 2AUWA 3QOXA 2JCGA 2IVGA 3FMYA 3FYAA 3PXPA 3GZDC 1UTXA 2GRLA 4I8TA 1B0NA 2HFZA 3OQMA 2AXZA 2ODRD 1JFSA 1Y9QA 2PXLA 3TRBA 4IWRA 1WH8A 1PRVA 1X2LA 3SCGA 4EQZA 3B7HA 5DRYA 3SX0A 2CSFA 3VWSA 1SQ8A 1Y7YA 4GHJA 1R63A 2HINA 3S8QA 2PXVA 1JFTA 2XXQA 1QP4A 3DM5A 2PPXA 4J1WA 2B5AA 5DTMA 3GZDA 3LFPA 2MEZA 1LCDA 3OKZA 3RZZA 3EUSA 4ER5A 4JCXA 1BDIA 2IV1A 3JXCL 1RZRA 2PIJA 1CJGA 1UXDA 4IVZA 2L49A 2PXBA 1DW9A 2BNMA 1ADRA 2XIUA 2PXEA 4YG1A 2MXDA 1ZZBA 2KPJA 5DTQA 1LLIA 1O4XA 2PXFA 1MFQC 4EKGA 3TEPA 4Q2JA
chains in the Genus database with same CATH topology
2PXDA 5GAGi 2FFHA 2PXVA 3LQXA 2PXBA 2PXKA 2PXLA 3DM5A 5GAHi 2XXAA 2PXPA 1HQ1A 3KL4A 2PXEA 2JQEA 2PXQA 2PXFA 2V3CC 1MFQC 1DULA 3NDBB 1QZXA 1QB2A 2PXTA 2PXUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PXD A;  5GAG i;  2FFH A;  2PXV A;  3LQX A;  2PXB A;  2PXK A;  2PXL A;  3DM5 A;  5GAH i;  2XXA A;  2PXP A;  1HQ1 A;  3KL4 A;  2PXE A;  2JQE A;  2PXQ A;  2PXF A;  2V3C C;  1MFQ C;  1DUL A;  3NDB B;  1QZX A;  1QB2 A;  2PXT A;  2PXU A; 
#chains in the Genus database with same CATH topology
 3OWQ A;  5GAG i;  2PUF A;  2LYP A;  3JXB C;  2JVL A;  1VPW A;  2XI8 A;  4MCX A;  2V3C C;  3TFL A;  2L8N A;  2LYS A;  2PUE A;  1QZX A;  1R69 A;  3H5T A;  3SCF A;  3F6W A;  4X4E A;  1LQC A;  3G0T A;  3KL4 A;  2JQE A;  4Y42 A;  3VK0 A;  1ZVV A;  2PUB A;  1HF0 A;  1L1M A;  3BDN A;  1OSL A;  3QF3 A;  1WIZ A;  1RZR D;  4ER3 A;  3L1P A;  2LCV A;  1ZZ9 A;  3KXA A;  3TEL A;  2H8R A;  4EK9 A;  3QFI A;  4Z5H A;  3GUU A;  1YSE A;  2BJC A;  3SCH A;  3A9Y A;  4MCT A;  2LNM A;  2XCJ A;  2GRM A;  3QQ6 A;  4X4F A;  2BNO A;  2LLV A;  1LMB 3;  2AXV A;  3CRO L;  1DUL A;  3GBF A;  4YG4 A;  1BDH A;  3U3W A;  1ZUG A;  1IC8 A;  4X4I A;  2VEO A;  2FFH A;  2LYL A;  3R1F A;  3UFD A;  4Z58 A;  2R63 A;  3MLF A;  3NRO A;  2FJR A;  1QP0 A;  2HCS A;  2HSG A;  2BNN A;  2PUA A;  2OR1 L;  3CEC A;  2J7W A;  3ZHI A;  3F52 A;  4YBA A;  3JXD L;  1UXC A;  1PNR A;  2YBD A;  4F8D A;  2LYJ A;  3KZ3 A;  3M9L A;  2O38 A;  3GN5 B;  2XSD C;  2IVQ A;  4ER6 A;  1DWK A;  4NDW A;  3KJX A;  2LYK A;  2PE5 A;  2M4H A;  1PRU A;  4I6U A;  2KZ8 A;  3PE5 A;  5K98 B;  2MQK A;  3GN5 A;  2R1J L;  2PXQ A;  2IUO A;  2KEK A;  2EF8 A;  1QB2 A;  3A9X A;  2PXU A;  5DT2 A;  4O8B A;  2CRO A;  2AW6 A;  2PXK A;  5GAH i;  2KEI A;  2J7U A;  3G7D A;  1QQA A;  4HRA A;  2EBY A;  4PU7 A;  3CLC A;  2OFY A;  2ICT A;  1GT0 C;  3D1N I;  4FBI A;  4EKI A;  2PUD A;  2HCN A;  1JWL A;  2EWT A;  2IU7 A;  1U2Z A;  4Z59 A;  4PU3 C;  1NER A;  3OQO A;  4X4G A;  1S7E A;  4ER0 A;  4J1X A;  2D5V A;  1HQ1 A;  1POU A;  1E3O C;  3OMT A;  1CQT A;  1QPZ A;  5A7L A;  1PER L;  4ER7 A;  3ZPX A;  3QYX A;  2XJ3 A;  3UWP A;  2L1P A;  3HZI B;  1OCT C;  2PUC A;  4JCY A;  2O4A A;  4PU4 C;  2LYQ A;  2KEJ A;  2XXA A;  3QOW A;  3FYM A;  4I6T A;  3G5G A;  4X4D A;  1RZS A;  3IVP A;  2AWI A;  3SR4 A;  1LCC A;  1JH9 A;  3LIS A;  4X4B A;  3LQX A;  3MEJ A;  1AU7 A;  4I6R A;  4X4H A;  1ZS4 A;  4DE8 A;  3GZC A;  2IVB A;  4YG7 B;  1ZPQ A;  1WET A;  1ZAY A;  3ME5 A;  2WUS R;  1QQB A;  4OB4 A;  3NDB B;  1RPE L;  1NW3 A;  1NEQ A;  3ZKC A;  1RIO A;  4Z5D A;  3QWG A;  3A9Z A;  1PRA A;  2PUG A;  1ZZ7 A;  2LLW A;  5DSX A;  3NXH A;  1ZZ8 A;  4DE9 A;  4FN3 A;  2XXP A;  3R09 A;  2PXP A;  1XWR A;  1WH6 A;  1ZZC A;  5JUW A;  4EZI A;  4PU8 A;  3F51 A;  3BS3 A;  3O9X A;  3ZHM A;  1ZZ6 A;  2A6C A;  3OQN A;  3DNV B;  5DTR A;  2O49 A;  4JQD A;  2PXD A;  3NZL A;  3BD1 A;  4Z5C A;  4OBM A;  1X57 A;  2LYR A;  4WVL A;  2GZU A;  5DRT A;  3OP9 A;  2WIU B;  4IA8 A;  4X4C A;  2PXT A;  1EFA A;  1QP7 A;  4GQM A;  2ICP A;  4YAR A;  2AXU A;  2AUW A;  3QOX A;  2JCG A;  2IVG A;  3FMY A;  3FYA A;  3PXP A;  3GZD C;  1UTX A;  2GRL A;  4I8T A;  1B0N A;  2HFZ A;  3OQM A;  2AXZ A;  2ODR D;  1JFS A;  1Y9Q A;  2PXL A;  3TRB A;  4IWR A;  1WH8 A;  1PRV A;  1X2L A;  3SCG A;  4EQZ A;  3B7H A;  5DRY A;  3SX0 A;  2CSF A;  3VWS A;  1SQ8 A;  1Y7Y A;  4GHJ A;  1R63 A;  2HIN A;  3S8Q A;  2PXV A;  1JFT A;  2XXQ A;  1QP4 A;  3DM5 A;  2PPX A;  4J1W A;  2B5A A;  5DTM A;  3GZD A;  3LFP A;  2MEZ A;  1LCD A;  3OKZ A;  3RZZ A;  3EUS A;  4ER5 A;  4JCX A;  1BDI A;  2IV1 A;  3JXC L;  1RZR A;  2PIJ A;  1CJG A;  1UXD A;  4IVZ A;  2L49 A;  2PXB A;  1DW9 A;  2BNM A;  1ADR A;  2XIU A;  2PXE A;  4YG1 A;  2MXD A;  1ZZB A;  2KPJ A;  5DTQ A;  1LLI A;  1O4X A;  2PXF A;  1MFQ C;  4EKG A;  3TEP A;  4Q2J A; 
#chains in the Genus database with same CATH homology
 2PXD A;  5GAG i;  2FFH A;  2PXV A;  3LQX A;  2PXB A;  2PXK A;  2PXL A;  3DM5 A;  5GAH i;  2XXA A;  2PXP A;  1HQ1 A;  3KL4 A;  2PXE A;  2JQE A;  2PXQ A;  2PXF A;  2V3C C;  1MFQ C;  1DUL A;  3NDB B;  1QZX A;  1QB2 A;  2PXT A;  2PXU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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