1MFQC

Crystal structure analysis of a ternary s-domain complex of human signal recognition particle
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
116
structure length
108
Chain Sequence
KHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMVKKMGGIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Induced structural changes of 7SL RNA during the assembly of human signal recognition particle
pubmed doi rcsb
molecule tags Signaling protein/rna
source organism Homo sapiens
molecule keywords 7S RNA of human SRP
total genus 32
structure length 108
sequence length 116
ec nomenclature
pdb deposition date 2002-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF02978 SRP_SPB Signal peptide binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.260.30 Mainly Alpha Orthogonal Bundle 434 Repressor (Amino-terminal Domain) Signal recognition particle, SRP54 subunit, M-domain 1mfqC00
1QB2A 1HQ1A 3NDBB 2PXPA 3DM5A 2PXEA 2FFHA 2PXDA 3LQXA 2PXQA 2PXKA 2XXAA 2PXLA 5GAGi 2JQEA 1QZXA 1DULA 2PXUA 2PXBA 1MFQC 2V3CC 2PXFA 3KL4A 2PXVA 2PXTA 5GAHi
chains in the Genus database with same CATH superfamily
4JCXA 2JVLA 2IU7A 2IUOA 2XIUA 1R69A 5GAGi 3OQNA 1NW3A 4PU7A 3TELA 1LMB3 5DRTA 2EBYA 3QYXA 3GUUA 3IVPA 5DTMA 4Z58A 2FFHA 1LCCA 3R09A 4Q2JA 4IWRA 3CROL 4I6TA 4Z5CA 3GBFA 2WIUB 2LYJA 3NXHA 4Y42A 3ZHIA 2PIJA 3OWQA 2CSFA 1UXCA 1JWLA 1LQCA 2AXZA 4ER6A 3U3WA 3HZIB 3JXDL 5DRYA 1ZZCA 3JXCL 3MEJA 4EQZA 4X4GA 3F51A 1AU7A 2LYSA 1R63A 1ZAYA 3SX0A 3UFDA 2PXTA 4Z5DA 3D1NI 1Y7YA 2LYPA 2AXUA 1WH6A 1DWKA 3TFLA 2PXDA 1LCDA 1X2LA 2XXAA 3L1PA 4FBIA 2AXVA 4I8TA 3H5TA 3FYAA 1WETA 2XXQA 1YSEA 3TRBA 2PXFA 3O9XA 1WH8A 3OQOA 5GAHi 2PE5A 2PUBA 4X4FA 2R1JL 3VK0A 2XSDC 3GZCA 1X57A 1ZZ9A 4MCXA 5DSXA 2O4AA 2BNOA 2VEOA 1PNRA 4FN3A 3SR4A 1U2ZA 2ICPA 2A6CA 2HSGA 2PUEA 3UWPA 2HCNA 2YBDA 1SQ8A 3LISA 3QQ6A 2MEZA 3A9ZA 3NDBB 2AUWA 4O8BA 2IVGA 2PUCA 3CLCA 4I6RA 2KZ8A 1VPWA 4X4IA 2OFYA 4F8DA 4IA8A 2XXPA 2LLVA 5DTRA 3TEPA 1NEQA 5DTQA 4YARA 1RIOA 1B0NA 2LLWA 2KEJA 2AWIA 3PE5A 3M9LA 2JQEA 4YG1A 2B5AA 3BDNA 4X4HA 3OP9A 4OBMA 2XI8A 3FMYA 4NDWA 1RZRA 2D5VA 1ZVVA 1POUA 1EFAA 2LCVA 3QFIA 2GRLA 1Y9QA 1BDIA 3SCFA 1QP4A 4EK9A 1QZXA 4OB4A 1MFQC 4ER0A 3G7DA 1ZZ7A 4JCYA 1ZZ6A 2BJCA 1QP7A 2PXPA 2J7WA 3VWSA 4WVLA 1S7EA 3DNVB 2LYLA 2HFZA 2WUSR 3SCGA 3MLFA 4J1WA 1JFTA 2GRMA 2O38A 4EZIA 2PPXA 1OSLA 3NZLA 2PUAA 2EWTA 4ER3A 3DM5A 4HRAA 4MCTA 2MQKA 2ICTA 3A9YA 3ZKCA 2BNNA 2IV1A 3LFPA 1WIZA 2EF8A 4PU4C 4DE8A 4ER5A 4X4EA 3R1FA 1JH9A 3ME5A 1LLIA 1QPZA 2XJ3A 2J7UA 5JUWA 3QOXA 2JCGA 4J1XA 4GQMA 2AW6A 2R63A 2MXDA 2PXLA 2XCJA 2KEIA 1HF0A 1QP0A 4Z5HA 1PRAA 3BS3A 3SCHA 1ZPQA 2V3CC 2LYQA 3F52A 1UTXA 3QOWA 2L49A 2PUDA 4YG7B 4EKGA 3ZHMA 2PXEA 3CECA 2M4HA 2L8NA 1JFSA 2IVQA 2LNMA 5DT2A 3GZDA 3GZDC 2PXBA 1OCTC 4X4DA 2H8RA 3ZPXA 4PU3C 2CROA 1PRVA 4EKIA 5K98B 1QB2A 4GHJA 2PUFA 2ODRD 2IVBA 3S8QA 4I6UA 4PU8A 2HINA 3PXPA 4DE9A 1ZZ8A 1ZZBA 3G0TA 3B7HA 1PERL 1L1MA 3A9XA 4YG4A 3BD1A 2L1PA 1BDHA 4X4BA 1QQBA 4ER7A 2KPJA 1DW9A 3G5GA 1XWRA 2HCSA 1RZRD 1UXDA 3LQXA 1ZUGA 2KEKA 4YBAA 2O49A 1DULA 1CJGA 3KL4A 4Z59A 2FJRA 3NROA 3OMTA 1CQTA 1ADRA 1HQ1A 5A7LA 3GN5A 3GN5B 2PUGA 4IVZA 1QQAA 2LYKA 1IC8A 1O4XA 2PXQA 2PXKA 3F6WA 3KJXA 2GZUA 4X4CA 2PXUA 2BNMA 2LYRA 2OR1L 3RZZA 3KZ3A 1ZS4A 3EUSA 3FYMA 1GT0C 3QF3A 3KXAA 3JXBC 1RPEL 3OQMA 1NERA 4JQDA 1RZSA 1PRUA 3OKZA 2PXVA 1E3OC 3QWGA
chains in the Genus database with same CATH topology
1QB2A 1HQ1A 3NDBB 2PXPA 3DM5A 2PXEA 2FFHA 2PXDA 3LQXA 2PXQA 2PXKA 2XXAA 2PXLA 5GAGi 2JQEA 1QZXA 1DULA 2PXUA 2PXBA 1MFQC 2V3CC 2PXFA 3KL4A 2PXVA 2PXTA 5GAHi
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QB2 A;  1HQ1 A;  3NDB B;  2PXP A;  3DM5 A;  2PXE A;  2FFH A;  2PXD A;  3LQX A;  2PXQ A;  2PXK A;  2XXA A;  2PXL A;  5GAG i;  2JQE A;  1QZX A;  1DUL A;  2PXU A;  2PXB A;  1MFQ C;  2V3C C;  2PXF A;  3KL4 A;  2PXV A;  2PXT A;  5GAH i; 
#chains in the Genus database with same CATH topology
 4JCX A;  2JVL A;  2IU7 A;  2IUO A;  2XIU A;  1R69 A;  5GAG i;  3OQN A;  1NW3 A;  4PU7 A;  3TEL A;  1LMB 3;  5DRT A;  2EBY A;  3QYX A;  3GUU A;  3IVP A;  5DTM A;  4Z58 A;  2FFH A;  1LCC A;  3R09 A;  4Q2J A;  4IWR A;  3CRO L;  4I6T A;  4Z5C A;  3GBF A;  2WIU B;  2LYJ A;  3NXH A;  4Y42 A;  3ZHI A;  2PIJ A;  3OWQ A;  2CSF A;  1UXC A;  1JWL A;  1LQC A;  2AXZ A;  4ER6 A;  3U3W A;  3HZI B;  3JXD L;  5DRY A;  1ZZC A;  3JXC L;  3MEJ A;  4EQZ A;  4X4G A;  3F51 A;  1AU7 A;  2LYS A;  1R63 A;  1ZAY A;  3SX0 A;  3UFD A;  2PXT A;  4Z5D A;  3D1N I;  1Y7Y A;  2LYP A;  2AXU A;  1WH6 A;  1DWK A;  3TFL A;  2PXD A;  1LCD A;  1X2L A;  2XXA A;  3L1P A;  4FBI A;  2AXV A;  4I8T A;  3H5T A;  3FYA A;  1WET A;  2XXQ A;  1YSE A;  3TRB A;  2PXF A;  3O9X A;  1WH8 A;  3OQO A;  5GAH i;  2PE5 A;  2PUB A;  4X4F A;  2R1J L;  3VK0 A;  2XSD C;  3GZC A;  1X57 A;  1ZZ9 A;  4MCX A;  5DSX A;  2O4A A;  2BNO A;  2VEO A;  1PNR A;  4FN3 A;  3SR4 A;  1U2Z A;  2ICP A;  2A6C A;  2HSG A;  2PUE A;  3UWP A;  2HCN A;  2YBD A;  1SQ8 A;  3LIS A;  3QQ6 A;  2MEZ A;  3A9Z A;  3NDB B;  2AUW A;  4O8B A;  2IVG A;  2PUC A;  3CLC A;  4I6R A;  2KZ8 A;  1VPW A;  4X4I A;  2OFY A;  4F8D A;  4IA8 A;  2XXP A;  2LLV A;  5DTR A;  3TEP A;  1NEQ A;  5DTQ A;  4YAR A;  1RIO A;  1B0N A;  2LLW A;  2KEJ A;  2AWI A;  3PE5 A;  3M9L A;  2JQE A;  4YG1 A;  2B5A A;  3BDN A;  4X4H A;  3OP9 A;  4OBM A;  2XI8 A;  3FMY A;  4NDW A;  1RZR A;  2D5V A;  1ZVV A;  1POU A;  1EFA A;  2LCV A;  3QFI A;  2GRL A;  1Y9Q A;  1BDI A;  3SCF A;  1QP4 A;  4EK9 A;  1QZX A;  4OB4 A;  1MFQ C;  4ER0 A;  3G7D A;  1ZZ7 A;  4JCY A;  1ZZ6 A;  2BJC A;  1QP7 A;  2PXP A;  2J7W A;  3VWS A;  4WVL A;  1S7E A;  3DNV B;  2LYL A;  2HFZ A;  2WUS R;  3SCG A;  3MLF A;  4J1W A;  1JFT A;  2GRM A;  2O38 A;  4EZI A;  2PPX A;  1OSL A;  3NZL A;  2PUA A;  2EWT A;  4ER3 A;  3DM5 A;  4HRA A;  4MCT A;  2MQK A;  2ICT A;  3A9Y A;  3ZKC A;  2BNN A;  2IV1 A;  3LFP A;  1WIZ A;  2EF8 A;  4PU4 C;  4DE8 A;  4ER5 A;  4X4E A;  3R1F A;  1JH9 A;  3ME5 A;  1LLI A;  1QPZ A;  2XJ3 A;  2J7U A;  5JUW A;  3QOX A;  2JCG A;  4J1X A;  4GQM A;  2AW6 A;  2R63 A;  2MXD A;  2PXL A;  2XCJ A;  2KEI A;  1HF0 A;  1QP0 A;  4Z5H A;  1PRA A;  3BS3 A;  3SCH A;  1ZPQ A;  2V3C C;  2LYQ A;  3F52 A;  1UTX A;  3QOW A;  2L49 A;  2PUD A;  4YG7 B;  4EKG A;  3ZHM A;  2PXE A;  3CEC A;  2M4H A;  2L8N A;  1JFS A;  2IVQ A;  2LNM A;  5DT2 A;  3GZD A;  3GZD C;  2PXB A;  1OCT C;  4X4D A;  2H8R A;  3ZPX A;  4PU3 C;  2CRO A;  1PRV A;  4EKI A;  5K98 B;  1QB2 A;  4GHJ A;  2PUF A;  2ODR D;  2IVB A;  3S8Q A;  4I6U A;  4PU8 A;  2HIN A;  3PXP A;  4DE9 A;  1ZZ8 A;  1ZZB A;  3G0T A;  3B7H A;  1PER L;  1L1M A;  3A9X A;  4YG4 A;  3BD1 A;  2L1P A;  1BDH A;  4X4B A;  1QQB A;  4ER7 A;  2KPJ A;  1DW9 A;  3G5G A;  1XWR A;  2HCS A;  1RZR D;  1UXD A;  3LQX A;  1ZUG A;  2KEK A;  4YBA A;  2O49 A;  1DUL A;  1CJG A;  3KL4 A;  4Z59 A;  2FJR A;  3NRO A;  3OMT A;  1CQT A;  1ADR A;  1HQ1 A;  5A7L A;  3GN5 A;  3GN5 B;  2PUG A;  4IVZ A;  1QQA A;  2LYK A;  1IC8 A;  1O4X A;  2PXQ A;  2PXK A;  3F6W A;  3KJX A;  2GZU A;  4X4C A;  2PXU A;  2BNM A;  2LYR A;  2OR1 L;  3RZZ A;  3KZ3 A;  1ZS4 A;  3EUS A;  3FYM A;  1GT0 C;  3QF3 A;  3KXA A;  3JXB C;  1RPE L;  3OQM A;  1NER A;  4JQD A;  1RZS A;  1PRU A;  3OKZ A;  2PXV A;  1E3O C;  3QWG A; 
#chains in the Genus database with same CATH homology
 1QB2 A;  1HQ1 A;  3NDB B;  2PXP A;  3DM5 A;  2PXE A;  2FFH A;  2PXD A;  3LQX A;  2PXQ A;  2PXK A;  2XXA A;  2PXL A;  5GAG i;  2JQE A;  1QZX A;  1DUL A;  2PXU A;  2PXB A;  1MFQ C;  2V3C C;  2PXF A;  3KL4 A;  2PXV A;  2PXT A;  5GAH i; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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