2HCNA

Crystal structure of rna dependent rna polymerase domain from west nile virus
Total Genus 174
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
174
sequence length
571
structure length
486
Chain Sequence
LVNGVVRLLSKPWDTITTKAPEPPEGVKYVLNETTNWLWAFLAREKRPRMCSREEFIRKVNSNAAQWRSAREAVEDPKFWEMVDEEREAHLRGECHTCRAIWFMWLGARFLEFEALGFLNEDHWLGRKNSGGGVEGLGLQKLGYILREVGTRPGGRIYADDTAGWDTRITRADLENEAKVLELLDGEHRRLARAIIELTYRSGQVVTYALNTFTNLAVQLVRMMEGEGVIGPDDVEKLTKGKGPKVRTWLSENGEERLSRMAVSGDDCVVKPLDDRFATSLHFLNAMSKVRKDIQEWKPSTGWYDWQQVPFCSNHFTELIMKDGRTLVTPCRGQDELVGRARISPNVRDTACLAKSYAQMWLLLYFHRRDLRLMANAICSAVPVNWVPTGRTTWSIHAGGEWMTTEDMLEVWNRVWIEENEWMEDKTPVEKWSDVPYSGKREDIWCGSLIGTRARATWAENIQVAINQVRSIIGDEKYVDYMSSLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
pubmed doi rcsb
molecule tags Transferase
source organism Kunjin virus
molecule keywords RNA-directed RNA polymerase (NS5)
total genus 174
structure length 486
sequence length 571
ec nomenclature ec 2.1.1.56: mRNA (guanine-N(7)-)-methyltransferase.
pdb deposition date 2006-06-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.260.90 Mainly Alpha Orthogonal Bundle 434 Repressor (Amino-terminal Domain) 434 Repressor (Amino-terminal Domain) 2hcnA03
2HFZA 2J7UA 2J7WA 3VWSA 2HCNA 2HCSA
chains in the Genus database with same CATH superfamily
2PXLA 3CLCA 3RZZA 1ZZBA 4Z59A 1NEQA 1SQ8A 2PXPA 4I8TA 2LLVA 1QQBA 2PXBA 2PUEA 3MEJA 1O4XA 3L1PA 2R63A 3KXAA 4F8DA 2BJCA 1IC8A 3A9YA 2O38A 1RZRA 5DTQA 3QYXA 3QOWA 4X4CA 2IU7A 3UFDA 2MQKA 3GZDC 2PXKA 1PRAA 2HCNA 3PXPA 2PXFA 2KEIA 4I6UA 3ME5A 3TRBA 4EQZA 1ZZCA 2PUFA 3GBFA 3H5TA 1ZZ8A 2XI8A 3SCHA 1ZZ6A 3A9ZA 2IV1A 3GN5B 2R1JL 4Y42A 2XCJA 3SR4A 1ZAYA 3ZHMA 3KJXA 2PXDA 1QP4A 3LFPA 3NZLA 1ZZ9A 2B5AA 1LQCA 3OQOA 3BDNA 2AXVA 4FBIA 1XWRA 4J1WA 4DE9A 1HQ1A 2L49A 3QWGA 5DTRA 2D5VA 1ZS4A 3JXBC 5JUWA 1YSEA 4X4EA 1WH8A 1PRVA 4MCXA 1ZPQA 3CECA 3R1FA 2LLWA 2PPXA 3OWQA 2EBYA 2LYLA 2ICPA 2IVGA 4X4DA 4GQMA 2PUBA 2PIJA 3QQ6A 5DTMA 2EF8A 2XXQA 2V3CC 3QOXA 1QZXA 2CROA 3BD1A 2GZUA 3F6WA 4IA8A 4Z5HA 1QB2A 1PNRA 1PERL 2PUAA 4MCTA 3NDBB 5GAHi 1RIOA 3SCFA 3FMYA 4YG1A 2OFYA 1MFQC 1Y9QA 2PUDA 3LISA 5A7LA 3VWSA 2IUOA 2IVQA 4GHJA 3U3WA 4PU4C 1UTXA 2AUWA 1NW3A 2HFZA 1L1MA 3ZPXA 1WH6A 2LYJA 4DE8A 2HCSA 2PXEA 3HZIB 4ER3A 3VK0A 3B7HA 1JFSA 1WIZA 4Z58A 1CJGA 4IVZA 1U2ZA 1RPEL 2PXQA 4ER0A 2FJRA 1OSLA 2MXDA 4EZIA 4JQDA 1VPWA 2XJ3A 1DWKA 1Y7YA 1ADRA 4YG4A 2BNOA 1LCDA 4JCYA 3EUSA 2PE5A 1ZUGA 1NERA 4PU3C 4OB4A 3SCGA 4IWRA 2O4AA 2HINA 2JCGA 4X4IA 2M4HA 2MEZA 2OR1L 3G5GA 3GN5A 2PUGA 2ODRD 4I6RA 4I6TA 3SX0A 5DSXA 3TELA 2LNMA 4EKIA 3NROA 4PU7A 3LQXA 3M9LA 2L1PA 3KZ3A 1R63A 3QFIA 5K98B 3BS3A 3R09A 1OCTC 2KPJA 1BDIA 3A9XA 3D1NI 3FYMA 3DM5A 2KEKA 3TEPA 1QPZA 1WETA 2O49A 2AWIA 1CQTA 2XXAA 4EK9A 2EWTA 2L8NA 3MLFA 4X4GA 4Z5DA 5GAGi 3DNVB 3TFLA 3UWPA 1LCCA 1PRUA 5DRYA 4FN3A 1DW9A 1R69A 2BNNA 4Q2JA 5DRTA 2H8RA 4JCXA 4HRAA 1UXCA 2LYPA 2XXPA 2A6CA 4YBAA 1QP0A 3F52A 4X4FA 2HSGA 3OP9A 3OQMA 2JVLA 1BDHA 3GZCA 1JH9A 2LYSA 1EFAA 1LLIA 2WUSR 3OQNA 3GUUA 2PUCA 2LYRA 2LYKA 3OKZA 1LMB3 2XIUA 1QQAA 2ICTA 1UXDA 1X57A 2JQEA 2CSFA 3ZKCA 2PXUA 3O9XA 2WIUB 2IVBA 2J7UA 4X4HA 4PU8A 4ER5A 3F51A 1RZSA 1DULA 3ZHIA 3JXDL 3KL4A 1JFTA 3G7DA 4ER7A 4WVLA 4YARA 2GRMA 1ZVVA 1GT0C 1X2LA 3NXHA 2YBDA 4ER6A 3OMTA 1B0NA 1AU7A 1QP7A 3PE5A 3G0TA 2LYQA 1HF0A 1E3OC 4NDWA 2PXVA 1S7EA 2LCVA 4X4BA 2KEJA 1RZRD 3GZDA 2GRLA 2PXTA 4O8BA 2VEOA 2AW6A 1ZZ7A 4Z5CA 2J7WA 4YG7B 4EKGA 3S8QA 3JXCL 3IVPA 2XSDC 4OBMA 2KZ8A 1JWLA 2AXUA 3FYAA 4J1XA 3QF3A 2BNMA 3CROL 5DT2A 1POUA 2AXZA 2FFHA
chains in the Genus database with same CATH topology
5DTMA 4ER3A 3GZDA 3NXHA 3NZLA 2J7UA 3ME5A 5JUWA 3A9XA 2ODRD 3A9YA 4EQZA 5DRYA 5DTQA 2XXQA 2YBDA 3GUUA 4ER6A 2VEOA 3QOXA 3SX0A 4ER5A 2J7WA 1U2ZA 3QOWA 3VWSA 4EKGA 5DSXA 3TELA 4Q2JA 5DRTA 3A9ZA 2LLWA 2LNMA 3TEPA 4EKIA 3NROA 4HRAA 4OBMA 3OKZA 3M9LA 3PE5A 3G0TA 2XXPA 3OWQA 2L1PA 3UWPA 1NW3A 2LLVA 4ER0A 3GZCA 4EK9A 3SR4A 2MXDA 3GZDC 4ER7A 4EZIA 3MEJA 3QFIA 2HFZA 4WVLA 4DE9A 5DT2A 2HCNA 3R09A 2M4HA 3ZPXA 5DTRA 3TFLA 4DE8A 2HCSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HFZ A;  2J7U A;  2J7W A;  3VWS A;  2HCN A;  2HCS A; 
#chains in the Genus database with same CATH topology
 2PXL A;  3CLC A;  3RZZ A;  1ZZB A;  4Z59 A;  1NEQ A;  1SQ8 A;  2PXP A;  4I8T A;  2LLV A;  1QQB A;  2PXB A;  2PUE A;  3MEJ A;  1O4X A;  3L1P A;  2R63 A;  3KXA A;  4F8D A;  2BJC A;  1IC8 A;  3A9Y A;  2O38 A;  1RZR A;  5DTQ A;  3QYX A;  3QOW A;  4X4C A;  2IU7 A;  3UFD A;  2MQK A;  3GZD C;  2PXK A;  1PRA A;  2HCN A;  3PXP A;  2PXF A;  2KEI A;  4I6U A;  3ME5 A;  3TRB A;  4EQZ A;  1ZZC A;  2PUF A;  3GBF A;  3H5T A;  1ZZ8 A;  2XI8 A;  3SCH A;  1ZZ6 A;  3A9Z A;  2IV1 A;  3GN5 B;  2R1J L;  4Y42 A;  2XCJ A;  3SR4 A;  1ZAY A;  3ZHM A;  3KJX A;  2PXD A;  1QP4 A;  3LFP A;  3NZL A;  1ZZ9 A;  2B5A A;  1LQC A;  3OQO A;  3BDN A;  2AXV A;  4FBI A;  1XWR A;  4J1W A;  4DE9 A;  1HQ1 A;  2L49 A;  3QWG A;  5DTR A;  2D5V A;  1ZS4 A;  3JXB C;  5JUW A;  1YSE A;  4X4E A;  1WH8 A;  1PRV A;  4MCX A;  1ZPQ A;  3CEC A;  3R1F A;  2LLW A;  2PPX A;  3OWQ A;  2EBY A;  2LYL A;  2ICP A;  2IVG A;  4X4D A;  4GQM A;  2PUB A;  2PIJ A;  3QQ6 A;  5DTM A;  2EF8 A;  2XXQ A;  2V3C C;  3QOX A;  1QZX A;  2CRO A;  3BD1 A;  2GZU A;  3F6W A;  4IA8 A;  4Z5H A;  1QB2 A;  1PNR A;  1PER L;  2PUA A;  4MCT A;  3NDB B;  5GAH i;  1RIO A;  3SCF A;  3FMY A;  4YG1 A;  2OFY A;  1MFQ C;  1Y9Q A;  2PUD A;  3LIS A;  5A7L A;  3VWS A;  2IUO A;  2IVQ A;  4GHJ A;  3U3W A;  4PU4 C;  1UTX A;  2AUW A;  1NW3 A;  2HFZ A;  1L1M A;  3ZPX A;  1WH6 A;  2LYJ A;  4DE8 A;  2HCS A;  2PXE A;  3HZI B;  4ER3 A;  3VK0 A;  3B7H A;  1JFS A;  1WIZ A;  4Z58 A;  1CJG A;  4IVZ A;  1U2Z A;  1RPE L;  2PXQ A;  4ER0 A;  2FJR A;  1OSL A;  2MXD A;  4EZI A;  4JQD A;  1VPW A;  2XJ3 A;  1DWK A;  1Y7Y A;  1ADR A;  4YG4 A;  2BNO A;  1LCD A;  4JCY A;  3EUS A;  2PE5 A;  1ZUG A;  1NER A;  4PU3 C;  4OB4 A;  3SCG A;  4IWR A;  2O4A A;  2HIN A;  2JCG A;  4X4I A;  2M4H A;  2MEZ A;  2OR1 L;  3G5G A;  3GN5 A;  2PUG A;  2ODR D;  4I6R A;  4I6T A;  3SX0 A;  5DSX A;  3TEL A;  2LNM A;  4EKI A;  3NRO A;  4PU7 A;  3LQX A;  3M9L A;  2L1P A;  3KZ3 A;  1R63 A;  3QFI A;  5K98 B;  3BS3 A;  3R09 A;  1OCT C;  2KPJ A;  1BDI A;  3A9X A;  3D1N I;  3FYM A;  3DM5 A;  2KEK A;  3TEP A;  1QPZ A;  1WET A;  2O49 A;  2AWI A;  1CQT A;  2XXA A;  4EK9 A;  2EWT A;  2L8N A;  3MLF A;  4X4G A;  4Z5D A;  5GAG i;  3DNV B;  3TFL A;  3UWP A;  1LCC A;  1PRU A;  5DRY A;  4FN3 A;  1DW9 A;  1R69 A;  2BNN A;  4Q2J A;  5DRT A;  2H8R A;  4JCX A;  4HRA A;  1UXC A;  2LYP A;  2XXP A;  2A6C A;  4YBA A;  1QP0 A;  3F52 A;  4X4F A;  2HSG A;  3OP9 A;  3OQM A;  2JVL A;  1BDH A;  3GZC A;  1JH9 A;  2LYS A;  1EFA A;  1LLI A;  2WUS R;  3OQN A;  3GUU A;  2PUC A;  2LYR A;  2LYK A;  3OKZ A;  1LMB 3;  2XIU A;  1QQA A;  2ICT A;  1UXD A;  1X57 A;  2JQE A;  2CSF A;  3ZKC A;  2PXU A;  3O9X A;  2WIU B;  2IVB A;  2J7U A;  4X4H A;  4PU8 A;  4ER5 A;  3F51 A;  1RZS A;  1DUL A;  3ZHI A;  3JXD L;  3KL4 A;  1JFT A;  3G7D A;  4ER7 A;  4WVL A;  4YAR A;  2GRM A;  1ZVV A;  1GT0 C;  1X2L A;  3NXH A;  2YBD A;  4ER6 A;  3OMT A;  1B0N A;  1AU7 A;  1QP7 A;  3PE5 A;  3G0T A;  2LYQ A;  1HF0 A;  1E3O C;  4NDW A;  2PXV A;  1S7E A;  2LCV A;  4X4B A;  2KEJ A;  1RZR D;  3GZD A;  2GRL A;  2PXT A;  4O8B A;  2VEO A;  2AW6 A;  1ZZ7 A;  4Z5C A;  2J7W A;  4YG7 B;  4EKG A;  3S8Q A;  3JXC L;  3IVP A;  2XSD C;  4OBM A;  2KZ8 A;  1JWL A;  2AXU A;  3FYA A;  4J1X A;  3QF3 A;  2BNM A;  3CRO L;  5DT2 A;  1POU A;  2AXZ A;  2FFH A; 
#chains in the Genus database with same CATH homology
 5DTM A;  4ER3 A;  3GZD A;  3NXH A;  3NZL A;  2J7U A;  3ME5 A;  5JUW A;  3A9X A;  2ODR D;  3A9Y A;  4EQZ A;  5DRY A;  5DTQ A;  2XXQ A;  2YBD A;  3GUU A;  4ER6 A;  2VEO A;  3QOX A;  3SX0 A;  4ER5 A;  2J7W A;  1U2Z A;  3QOW A;  3VWS A;  4EKG A;  5DSX A;  3TEL A;  4Q2J A;  5DRT A;  3A9Z A;  2LLW A;  2LNM A;  3TEP A;  4EKI A;  3NRO A;  4HRA A;  4OBM A;  3OKZ A;  3M9L A;  3PE5 A;  3G0T A;  2XXP A;  3OWQ A;  2L1P A;  3UWP A;  1NW3 A;  2LLV A;  4ER0 A;  3GZC A;  4EK9 A;  3SR4 A;  2MXD A;  3GZD C;  4ER7 A;  4EZI A;  3MEJ A;  3QFI A;  2HFZ A;  4WVL A;  4DE9 A;  5DT2 A;  2HCN A;  3R09 A;  2M4H A;  3ZPX A;  5DTR A;  3TFL A;  4DE8 A;  2HCS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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