2HCNA

Crystal structure of rna dependent rna polymerase domain from west nile virus
Total Genus 174
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
174
sequence length
571
structure length
486
Chain Sequence
LVNGVVRLLSKPWDTITTKAPEPPEGVKYVLNETTNWLWAFLAREKRPRMCSREEFIRKVNSNAAQWRSAREAVEDPKFWEMVDEEREAHLRGECHTCRAIWFMWLGARFLEFEALGFLNEDHWLGRKNSGGGVEGLGLQKLGYILREVGTRPGGRIYADDTAGWDTRITRADLENEAKVLELLDGEHRRLARAIIELTYRSGQVVTYALNTFTNLAVQLVRMMEGEGVIGPDDVEKLTKGKGPKVRTWLSENGEERLSRMAVSGDDCVVKPLDDRFATSLHFLNAMSKVRKDIQEWKPSTGWYDWQQVPFCSNHFTELIMKDGRTLVTPCRGQDELVGRARISPNVRDTACLAKSYAQMWLLLYFHRRDLRLMANAICSAVPVNWVPTGRTTWSIHAGGEWMTTEDMLEVWNRVWIEENEWMEDKTPVEKWSDVPYSGKREDIWCGSLIGTRARATWAENIQVAINQVRSIIGDEKYVDYMSSLK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
pubmed doi rcsb
molecule tags Transferase
source organism Kunjin virus
molecule keywords RNA-directed RNA polymerase (NS5)
total genus 174
structure length 486
sequence length 571
ec nomenclature ec 2.1.1.56: mRNA (guanine-N(7)-)-methyltransferase.
pdb deposition date 2006-06-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.260.90 Mainly Alpha Orthogonal Bundle 434 Repressor (Amino-terminal Domain) 434 Repressor (Amino-terminal Domain) 2hcnA03
2HCSA 2J7UA 2HCNA 2HFZA 3VWSA 2J7WA
chains in the Genus database with same CATH superfamily
2PIJA 4JCXA 1E3OC 2LCVA 3PXPA 3R1FA 3QWGA 4J1XA 3TEPA 1OSLA 3ZHMA 4Z5HA 1ZUGA 2XSDC 1HQ1A 2BNNA 3H5TA 3B7HA 2BJCA 2PUDA 3OP9A 4JCYA 1ZZ9A 2XCJA 2PXVA 5DTQA 3BS3A 3CROL 3LISA 2A6CA 2ICPA 1L1MA 3A9YA 1PRUA 4X4CA 3PE5A 4WVLA 4ER0A 1QB2A 3KL4A 3TFLA 4Z5DA 2XXPA 3M9LA 4YG4A 1DWKA 2O4AA 2OR1L 3ZPXA 2AWIA 1RPEL 3GN5A 4EQZA 2XXAA 3GZCA 2CSFA 2IU7A 4J1WA 1IC8A 1ZZCA 2EF8A 3ZKCA 1LLIA 1B0NA 2PE5A 3JXBC 4Q2JA 3OQOA 2KEJA 2LLWA 4I6UA 5DT2A 3L1PA 2ICTA 3KZ3A 3OKZA 2AW6A 4ER7A 1QP7A 1ZPQA 1LQCA 3SX0A 5DRTA 4X4EA 4I6RA 3SCFA 2EWTA 4O8BA 4X4FA 1O4XA 3NXHA 1PERL 2IVBA 1ADRA 3OMTA 4YARA 4X4BA 3NZLA 1AU7A 1X2LA 3JXDL 3VK0A 2PUFA 2GZUA 2LYPA 2D5VA 2KEKA 3QOWA 2M4HA 4MCXA 1LCCA 2HCSA 3GZDC 2MEZA 3MLFA 4JQDA 4X4DA 4IVZA 3BD1A 4NDWA 1RZRD 2LLVA 2PXTA 1SQ8A 4PU3C 1QZXA 5DTMA 4IWRA 4HRAA 1Y7YA 3KXAA 2PXKA 1DW9A 2PUBA 3OQMA 4EZIA 4YG1A 2J7WA 2AXUA 2PXBA 2LYSA 1OCTC 3KJXA 3TRBA 3UWPA 3SR4A 1QPZA 3IVPA 4DE9A 1UTXA 4OBMA 4PU7A 5DRYA 1ZZ6A 1BDHA 2FFHA 1HF0A 4I6TA 1S7EA 2LYRA 3QYXA 2PXFA 4ER3A 1JFSA 4Z58A 2AUWA 1WETA 1NW3A 2EBYA 1CQTA 5DSXA 3R09A 2PUCA 2IUOA 2BNOA 1Y9QA 1WIZA 3LQXA 2R1JL 3CLCA 3FMYA 2PUGA 4EKIA 2LNMA 2HSGA 1VPWA 1QP4A 1ZZ7A 2PXQA 1JFTA 1CJGA 4YBAA 3OQNA 3U3WA 3FYMA 1ZZ8A 4ER5A 3QQ6A 2LYKA 2J7UA 2OFYA 1RZSA 2HINA 4GHJA 3G0TA 2GRLA 4OB4A 3VWSA 1NEQA 3GUUA 3ME5A 3GBFA 1R63A 2FJRA 3F51A 2PUAA 2XI8A 4EK9A 3MEJA 4EKGA 2CROA 4PU4C 3QF3A 4PU8A 3DM5A 4Z5CA 1WH6A 3DNVB 4FBIA 1NERA 4DE8A 4X4GA 2IV1A 1XWRA 3G7DA 3TELA 2ODRD 3O9XA 1ZS4A 1LMB3 2KPJA 2YBDA 2WUSR 3SCGA 2L8NA 3EUSA 4Z59A 2MQKA 4I8TA 3RZZA 1RZRA 2IVGA 2O38A 2WIUB 1ZZBA 1QP0A 3S8QA 2R63A 2PXPA 2JVLA 1GT0C 2L1PA 1JWLA 3FYAA 2IVQA 2JQEA 1ZAYA 3F6WA 3GZDA 2PXDA 3JXCL 3A9ZA 1PRVA 3CECA 1LCDA 3BDNA 5GAGi 3GN5B 4YG7B 1UXDA 2H8RA 2XIUA 3QFIA 3LFPA 2KEIA 1BDIA 1YSEA 2XXQA 2HCNA 2BNMA 4ER6A 1DULA 1JH9A 5DTRA 1WH8A 3NDBB 5JUWA 2AXVA 1R69A 1PRAA 1EFAA 4Y42A 2LYQA 5K98B 2LYJA 2B5AA 2HFZA 1ZVVA 1POUA 3NROA 4FN3A 1MFQC 2AXZA 4IA8A 2MXDA 2PXEA 3ZHIA 1U2ZA 2KZ8A 4X4IA 2V3CC 3A9XA 2GRMA 4MCTA 1PNRA 3UFDA 1RIOA 2JCGA 2PXLA 1QQBA 4X4HA 4F8DA 3QOXA 3SCHA 3D1NI 2LYLA 2PPXA 3F52A 1X57A 2XJ3A 1QQAA 5A7LA 2VEOA 2PUEA 3HZIB 3OWQA 2L49A 4GQMA 2O49A 3G5GA 1UXCA 2PXUA 5GAHi
chains in the Genus database with same CATH topology
1U2ZA 3ZPXA 3ME5A 4EZIA 4ER3A 3OKZA 3TEPA 4EQZA 4DE8A 2J7WA 4ER7A 3A9XA 3NZLA 3GZCA 5DRTA 3SX0A 1NW3A 4EK9A 3A9YA 3MEJA 3QFIA 5DSXA 4EKGA 3PE5A 2LLVA 3R09A 2VEOA 3TELA 2XXQA 2ODRD 2L1PA 4WVLA 3SR4A 3UWPA 4ER5A 4ER0A 4DE9A 2J7UA 2HCNA 2YBDA 2HFZA 3OWQA 3QOWA 2M4HA 4OBMA 4Q2JA 3TFLA 4EKIA 4ER6A 2XXPA 3M9LA 3GZDA 2LNMA 3NROA 5DRYA 5DTMA 2HCSA 2LLWA 2MXDA 5DTRA 4HRAA 3GZDC 3QOXA 3G0TA 5DTQA 5DT2A 3NXHA 3A9ZA 3VWSA 5JUWA 3GUUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HCS A;  2J7U A;  2HCN A;  2HFZ A;  3VWS A;  2J7W A; 
#chains in the Genus database with same CATH topology
 2PIJ A;  4JCX A;  1E3O C;  2LCV A;  3PXP A;  3R1F A;  3QWG A;  4J1X A;  3TEP A;  1OSL A;  3ZHM A;  4Z5H A;  1ZUG A;  2XSD C;  1HQ1 A;  2BNN A;  3H5T A;  3B7H A;  2BJC A;  2PUD A;  3OP9 A;  4JCY A;  1ZZ9 A;  2XCJ A;  2PXV A;  5DTQ A;  3BS3 A;  3CRO L;  3LIS A;  2A6C A;  2ICP A;  1L1M A;  3A9Y A;  1PRU A;  4X4C A;  3PE5 A;  4WVL A;  4ER0 A;  1QB2 A;  3KL4 A;  3TFL A;  4Z5D A;  2XXP A;  3M9L A;  4YG4 A;  1DWK A;  2O4A A;  2OR1 L;  3ZPX A;  2AWI A;  1RPE L;  3GN5 A;  4EQZ A;  2XXA A;  3GZC A;  2CSF A;  2IU7 A;  4J1W A;  1IC8 A;  1ZZC A;  2EF8 A;  3ZKC A;  1LLI A;  1B0N A;  2PE5 A;  3JXB C;  4Q2J A;  3OQO A;  2KEJ A;  2LLW A;  4I6U A;  5DT2 A;  3L1P A;  2ICT A;  3KZ3 A;  3OKZ A;  2AW6 A;  4ER7 A;  1QP7 A;  1ZPQ A;  1LQC A;  3SX0 A;  5DRT A;  4X4E A;  4I6R A;  3SCF A;  2EWT A;  4O8B A;  4X4F A;  1O4X A;  3NXH A;  1PER L;  2IVB A;  1ADR A;  3OMT A;  4YAR A;  4X4B A;  3NZL A;  1AU7 A;  1X2L A;  3JXD L;  3VK0 A;  2PUF A;  2GZU A;  2LYP A;  2D5V A;  2KEK A;  3QOW A;  2M4H A;  4MCX A;  1LCC A;  2HCS A;  3GZD C;  2MEZ A;  3MLF A;  4JQD A;  4X4D A;  4IVZ A;  3BD1 A;  4NDW A;  1RZR D;  2LLV A;  2PXT A;  1SQ8 A;  4PU3 C;  1QZX A;  5DTM A;  4IWR A;  4HRA A;  1Y7Y A;  3KXA A;  2PXK A;  1DW9 A;  2PUB A;  3OQM A;  4EZI A;  4YG1 A;  2J7W A;  2AXU A;  2PXB A;  2LYS A;  1OCT C;  3KJX A;  3TRB A;  3UWP A;  3SR4 A;  1QPZ A;  3IVP A;  4DE9 A;  1UTX A;  4OBM A;  4PU7 A;  5DRY A;  1ZZ6 A;  1BDH A;  2FFH A;  1HF0 A;  4I6T A;  1S7E A;  2LYR A;  3QYX A;  2PXF A;  4ER3 A;  1JFS A;  4Z58 A;  2AUW A;  1WET A;  1NW3 A;  2EBY A;  1CQT A;  5DSX A;  3R09 A;  2PUC A;  2IUO A;  2BNO A;  1Y9Q A;  1WIZ A;  3LQX A;  2R1J L;  3CLC A;  3FMY A;  2PUG A;  4EKI A;  2LNM A;  2HSG A;  1VPW A;  1QP4 A;  1ZZ7 A;  2PXQ A;  1JFT A;  1CJG A;  4YBA A;  3OQN A;  3U3W A;  3FYM A;  1ZZ8 A;  4ER5 A;  3QQ6 A;  2LYK A;  2J7U A;  2OFY A;  1RZS A;  2HIN A;  4GHJ A;  3G0T A;  2GRL A;  4OB4 A;  3VWS A;  1NEQ A;  3GUU A;  3ME5 A;  3GBF A;  1R63 A;  2FJR A;  3F51 A;  2PUA A;  2XI8 A;  4EK9 A;  3MEJ A;  4EKG A;  2CRO A;  4PU4 C;  3QF3 A;  4PU8 A;  3DM5 A;  4Z5C A;  1WH6 A;  3DNV B;  4FBI A;  1NER A;  4DE8 A;  4X4G A;  2IV1 A;  1XWR A;  3G7D A;  3TEL A;  2ODR D;  3O9X A;  1ZS4 A;  1LMB 3;  2KPJ A;  2YBD A;  2WUS R;  3SCG A;  2L8N A;  3EUS A;  4Z59 A;  2MQK A;  4I8T A;  3RZZ A;  1RZR A;  2IVG A;  2O38 A;  2WIU B;  1ZZB A;  1QP0 A;  3S8Q A;  2R63 A;  2PXP A;  2JVL A;  1GT0 C;  2L1P A;  1JWL A;  3FYA A;  2IVQ A;  2JQE A;  1ZAY A;  3F6W A;  3GZD A;  2PXD A;  3JXC L;  3A9Z A;  1PRV A;  3CEC A;  1LCD A;  3BDN A;  5GAG i;  3GN5 B;  4YG7 B;  1UXD A;  2H8R A;  2XIU A;  3QFI A;  3LFP A;  2KEI A;  1BDI A;  1YSE A;  2XXQ A;  2HCN A;  2BNM A;  4ER6 A;  1DUL A;  1JH9 A;  5DTR A;  1WH8 A;  3NDB B;  5JUW A;  2AXV A;  1R69 A;  1PRA A;  1EFA A;  4Y42 A;  2LYQ A;  5K98 B;  2LYJ A;  2B5A A;  2HFZ A;  1ZVV A;  1POU A;  3NRO A;  4FN3 A;  1MFQ C;  2AXZ A;  4IA8 A;  2MXD A;  2PXE A;  3ZHI A;  1U2Z A;  2KZ8 A;  4X4I A;  2V3C C;  3A9X A;  2GRM A;  4MCT A;  1PNR A;  3UFD A;  1RIO A;  2JCG A;  2PXL A;  1QQB A;  4X4H A;  4F8D A;  3QOX A;  3SCH A;  3D1N I;  2LYL A;  2PPX A;  3F52 A;  1X57 A;  2XJ3 A;  1QQA A;  5A7L A;  2VEO A;  2PUE A;  3HZI B;  3OWQ A;  2L49 A;  4GQM A;  2O49 A;  3G5G A;  1UXC A;  2PXU A;  5GAH i; 
#chains in the Genus database with same CATH homology
 1U2Z A;  3ZPX A;  3ME5 A;  4EZI A;  4ER3 A;  3OKZ A;  3TEP A;  4EQZ A;  4DE8 A;  2J7W A;  4ER7 A;  3A9X A;  3NZL A;  3GZC A;  5DRT A;  3SX0 A;  1NW3 A;  4EK9 A;  3A9Y A;  3MEJ A;  3QFI A;  5DSX A;  4EKG A;  3PE5 A;  2LLV A;  3R09 A;  2VEO A;  3TEL A;  2XXQ A;  2ODR D;  2L1P A;  4WVL A;  3SR4 A;  3UWP A;  4ER5 A;  4ER0 A;  4DE9 A;  2J7U A;  2HCN A;  2YBD A;  2HFZ A;  3OWQ A;  3QOW A;  2M4H A;  4OBM A;  4Q2J A;  3TFL A;  4EKI A;  4ER6 A;  2XXP A;  3M9L A;  3GZD A;  2LNM A;  3NRO A;  5DRY A;  5DTM A;  2HCS A;  2LLW A;  2MXD A;  5DTR A;  4HRA A;  3GZD C;  3QOX A;  3G0T A;  5DTQ A;  5DT2 A;  3NXH A;  3A9Z A;  3VWS A;  5JUW A;  3GUU A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...