2HCSA

Crystal structure of rna dependant rna polymerase domain of west nile virus
Total Genus 175
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
570
structure length
487
Chain Sequence
LVNGVVRLLSKPWDTIDTKAPEPPEGVKYVLNETTNWLWAFLAREKRPRMCSREEFIRKVNSNAAQWRSAREAVEDPKFWEMVDEEREAHLRGECHTCSRAIWFMWLGARFLEFEALGFLNEDHWLGRKNSGGGVEGLGLQKLGYILREVGTRPGGRIYADDTAGWDTRITRADLENEAKVLELLDGEHRRLARAIIELTYRGSGQVVTYALNTFTNLAVQLVRMMEGEGVIGPDDVEKLTKGKGPKVRTWLSENGEERLSRMAVSGDDCVVKPLDDRFATSLHFLNAMSKVRKDIQEWKPSTGWYDWQQVPFCSNHFTELIMKDGRTLVTPCRGQDELVGRARISPNVRDTACLAKSYAQMWLLLYFHRRDLRLMANAICSAVPVNWVPTGRTTWSIHAGGEWMTTEDMLEVWNRVWIEENEWMEDKTPVEKWSDVPYSGKREDIWCGSLIGTRARATWAENIQVAINQVRSIIGDEKYVDYMSSL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
pubmed doi rcsb
molecule tags Transferase
source organism Kunjin virus
molecule keywords RNA-directed RNA polymerase (NS5)
total genus 175
structure length 487
sequence length 570
ec nomenclature ec 2.1.1.56: mRNA (guanine-N(7)-)-methyltransferase.
pdb deposition date 2006-06-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.260.90 Mainly Alpha Orthogonal Bundle 434 Repressor (Amino-terminal Domain) 434 Repressor (Amino-terminal Domain) 2hcsA03
2J7UA 3VWSA 2J7WA 2HCSA 2HCNA 2HFZA
chains in the Genus database with same CATH superfamily
1ADRA 2GRMA 2YBDA 4DE9A 3ZHMA 2FFHA 3B7HA 4I6TA 3OKZA 2ODRD 3KL4A 2AXUA 1R69A 3OQOA 2BNMA 3SCFA 5GAHi 2XJ3A 1X57A 4MCTA 2HCNA 3OWQA 2CROA 3RZZA 1DULA 1RPEL 1SQ8A 3PXPA 2D5VA 5DT2A 4WVLA 4Z5HA 4YG4A 2KEJA 3EUSA 3A9ZA 2LYLA 1JFTA 3CLCA 1Y9QA 3GZDC 3ZHIA 2EF8A 4EK9A 4YG7B 3DNVB 4YG1A 3TFLA 2O49A 2LLWA 1NERA 2PXLA 2HFZA 2HSGA 1QP7A 4EKIA 3U3WA 2IVGA 2JQEA 1HQ1A 4X4GA 4OB4A 3JXBC 2M4HA 2PXKA 1WIZA 2PXQA 2O4AA 1O4XA 3QOXA 4Z58A 3SCGA 4F8DA 2BNOA 2LNMA 1OSLA 1LCCA 2A6CA 4FBIA 3GZCA 3OQNA 3O9XA 4NDWA 1L1MA 4ER3A 3R09A 1OCTC 4Y42A 3TEPA 1QP4A 3JXCL 1JFSA 1RZRD 3GUUA 3HZIB 4PU8A 2PXVA 2GZUA 2XCJA 2IVQA 2PXDA 4X4CA 1BDIA 5A7LA 3KZ3A 3SX0A 2PIJA 4EKGA 2WIUB 4J1XA 2WUSR 3A9YA 3LISA 1WH8A 1ZUGA 5DTRA 2PUAA 4ER6A 3CECA 5DTQA 3H5TA 4DE8A 4X4HA 2HINA 1BDHA 3KJXA 3M9LA 2EWTA 3NDBB 1NEQA 2AWIA 1MFQC 5DSXA 2XIUA 4OBMA 2LYRA 3QWGA 3JXDL 2OFYA 2PPXA 3G7DA 2PUEA 5K98B 1ZVVA 3CROL 4X4EA 1ZAYA 1ZZBA 1JWLA 3G5GA 3OMTA 2XXQA 2EBYA 2LYKA 2AXZA 4Z5CA 3PE5A 1RZRA 1UXDA 3S8QA 4PU3C 2PXPA 3UWPA 5DTMA 4J1WA 3BDNA 3QYXA 1ZZ9A 2JVLA 3A9XA 3GN5B 4YARA 2B5AA 3IVPA 1EFAA 1WETA 1PRUA 3D1NI 3FYMA 2R1JL 5JUWA 1ZZ7A 4EZIA 2O38A 3GZDA 3L1PA 4PU4C 4X4IA 1AU7A 3QFIA 3NXHA 1ZZ6A 2OR1L 4Q2JA 2PXBA 4I8TA 3SCHA 2CSFA 3GN5A 3TRBA 3MEJA 1ZZ8A 1NW3A 3FYAA 2MEZA 1HF0A 3FMYA 2XXAA 4JCXA 2PUBA 1VPWA 2LCVA 1QZXA 3R1FA 1PERL 4I6UA 4PU7A 1Y7YA 2XI8A 3ME5A 3BS3A 5GAGi 2ICPA 4IA8A 2IV1A 5DRTA 1YSEA 2IUOA 3KXAA 1PNRA 3LQXA 1QQBA 2L1PA 1RZSA 1QP0A 3VK0A 4ER5A 1RIOA 2PE5A 3QF3A 2PXTA 4Z5DA 3DM5A 3ZKCA 2XXPA 2PUDA 2H8RA 1LQCA 4FN3A 4IWRA 1DW9A 1S7EA 3QQ6A 2KEIA 4ER7A 2BJCA 4HRAA 2BNNA 3SR4A 3VWSA 2GRLA 2V3CC 1DWKA 2KZ8A 1WH6A 3OP9A 1ZPQA 1QPZA 4JQDA 3F52A 2PXEA 1UTXA 4EQZA 2KPJA 3BD1A 4ER0A 3OQMA 2ICTA 3QOWA 1CJGA 4JCYA 3MLFA 3LFPA 2LLVA 2PUGA 3GBFA 1LMB3 5DRYA 4GHJA 1IC8A 2XSDC 2J7UA 4O8BA 2L49A 3NROA 2PXFA 1LLIA 1LCDA 2VEOA 4IVZA 2KEKA 1E3OC 2PUFA 4GQMA 1ZS4A 2LYQA 3UFDA 1UXCA 2MQKA 2PXUA 2LYPA 3G0TA 2LYSA 2AW6A 3F51A 2IVBA 4MCXA 2IU7A 1U2ZA 1X2LA 1POUA 1GT0C 2R63A 2MXDA 2JCGA 2L8NA 4X4BA 3ZPXA 2AXVA 1R63A 3TELA 2AUWA 4X4DA 4X4FA 1QB2A 1PRAA 1XWRA 2J7WA 2HCSA 4YBAA 3NZLA 4Z59A 2PUCA 4I6RA 1QQAA 2FJRA 3F6WA 1PRVA 1ZZCA 1B0NA 2LYJA 1JH9A 1CQTA
chains in the Genus database with same CATH topology
4HRAA 5DT2A 3TELA 3NXHA 5DTRA 3SR4A 2YBDA 3A9XA 3QFIA 3VWSA 3TEPA 2XXQA 4Q2JA 2L1PA 4WVLA 5DRYA 3TFLA 4ER6A 4DE9A 2LLWA 3G0TA 5DTQA 4DE8A 3OKZA 2ODRD 3QOXA 4ER5A 2J7UA 3PE5A 3GUUA 2J7WA 2HCSA 3ME5A 3MEJA 3NZLA 2HFZA 1NW3A 4EQZA 2LNMA 3NROA 3A9ZA 5JUWA 4EKIA 2XXPA 3GZCA 3UWPA 4ER0A 5DTMA 1U2ZA 3M9LA 4EZIA 2VEOA 2HCNA 3GZDA 3SX0A 4EK9A 3OWQA 3QOWA 2MXDA 5DRTA 4EKGA 3GZDC 5DSXA 2LLVA 3A9YA 4OBMA 4ER3A 3ZPXA 4ER7A 3R09A 2M4HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J7U A;  3VWS A;  2J7W A;  2HCS A;  2HCN A;  2HFZ A; 
#chains in the Genus database with same CATH topology
 1ADR A;  2GRM A;  2YBD A;  4DE9 A;  3ZHM A;  2FFH A;  3B7H A;  4I6T A;  3OKZ A;  2ODR D;  3KL4 A;  2AXU A;  1R69 A;  3OQO A;  2BNM A;  3SCF A;  5GAH i;  2XJ3 A;  1X57 A;  4MCT A;  2HCN A;  3OWQ A;  2CRO A;  3RZZ A;  1DUL A;  1RPE L;  1SQ8 A;  3PXP A;  2D5V A;  5DT2 A;  4WVL A;  4Z5H A;  4YG4 A;  2KEJ A;  3EUS A;  3A9Z A;  2LYL A;  1JFT A;  3CLC A;  1Y9Q A;  3GZD C;  3ZHI A;  2EF8 A;  4EK9 A;  4YG7 B;  3DNV B;  4YG1 A;  3TFL A;  2O49 A;  2LLW A;  1NER A;  2PXL A;  2HFZ A;  2HSG A;  1QP7 A;  4EKI A;  3U3W A;  2IVG A;  2JQE A;  1HQ1 A;  4X4G A;  4OB4 A;  3JXB C;  2M4H A;  2PXK A;  1WIZ A;  2PXQ A;  2O4A A;  1O4X A;  3QOX A;  4Z58 A;  3SCG A;  4F8D A;  2BNO A;  2LNM A;  1OSL A;  1LCC A;  2A6C A;  4FBI A;  3GZC A;  3OQN A;  3O9X A;  4NDW A;  1L1M A;  4ER3 A;  3R09 A;  1OCT C;  4Y42 A;  3TEP A;  1QP4 A;  3JXC L;  1JFS A;  1RZR D;  3GUU A;  3HZI B;  4PU8 A;  2PXV A;  2GZU A;  2XCJ A;  2IVQ A;  2PXD A;  4X4C A;  1BDI A;  5A7L A;  3KZ3 A;  3SX0 A;  2PIJ A;  4EKG A;  2WIU B;  4J1X A;  2WUS R;  3A9Y A;  3LIS A;  1WH8 A;  1ZUG A;  5DTR A;  2PUA A;  4ER6 A;  3CEC A;  5DTQ A;  3H5T A;  4DE8 A;  4X4H A;  2HIN A;  1BDH A;  3KJX A;  3M9L A;  2EWT A;  3NDB B;  1NEQ A;  2AWI A;  1MFQ C;  5DSX A;  2XIU A;  4OBM A;  2LYR A;  3QWG A;  3JXD L;  2OFY A;  2PPX A;  3G7D A;  2PUE A;  5K98 B;  1ZVV A;  3CRO L;  4X4E A;  1ZAY A;  1ZZB A;  1JWL A;  3G5G A;  3OMT A;  2XXQ A;  2EBY A;  2LYK A;  2AXZ A;  4Z5C A;  3PE5 A;  1RZR A;  1UXD A;  3S8Q A;  4PU3 C;  2PXP A;  3UWP A;  5DTM A;  4J1W A;  3BDN A;  3QYX A;  1ZZ9 A;  2JVL A;  3A9X A;  3GN5 B;  4YAR A;  2B5A A;  3IVP A;  1EFA A;  1WET A;  1PRU A;  3D1N I;  3FYM A;  2R1J L;  5JUW A;  1ZZ7 A;  4EZI A;  2O38 A;  3GZD A;  3L1P A;  4PU4 C;  4X4I A;  1AU7 A;  3QFI A;  3NXH A;  1ZZ6 A;  2OR1 L;  4Q2J A;  2PXB A;  4I8T A;  3SCH A;  2CSF A;  3GN5 A;  3TRB A;  3MEJ A;  1ZZ8 A;  1NW3 A;  3FYA A;  2MEZ A;  1HF0 A;  3FMY A;  2XXA A;  4JCX A;  2PUB A;  1VPW A;  2LCV A;  1QZX A;  3R1F A;  1PER L;  4I6U A;  4PU7 A;  1Y7Y A;  2XI8 A;  3ME5 A;  3BS3 A;  5GAG i;  2ICP A;  4IA8 A;  2IV1 A;  5DRT A;  1YSE A;  2IUO A;  3KXA A;  1PNR A;  3LQX A;  1QQB A;  2L1P A;  1RZS A;  1QP0 A;  3VK0 A;  4ER5 A;  1RIO A;  2PE5 A;  3QF3 A;  2PXT A;  4Z5D A;  3DM5 A;  3ZKC A;  2XXP A;  2PUD A;  2H8R A;  1LQC A;  4FN3 A;  4IWR A;  1DW9 A;  1S7E A;  3QQ6 A;  2KEI A;  4ER7 A;  2BJC A;  4HRA A;  2BNN A;  3SR4 A;  3VWS A;  2GRL A;  2V3C C;  1DWK A;  2KZ8 A;  1WH6 A;  3OP9 A;  1ZPQ A;  1QPZ A;  4JQD A;  3F52 A;  2PXE A;  1UTX A;  4EQZ A;  2KPJ A;  3BD1 A;  4ER0 A;  3OQM A;  2ICT A;  3QOW A;  1CJG A;  4JCY A;  3MLF A;  3LFP A;  2LLV A;  2PUG A;  3GBF A;  1LMB 3;  5DRY A;  4GHJ A;  1IC8 A;  2XSD C;  2J7U A;  4O8B A;  2L49 A;  3NRO A;  2PXF A;  1LLI A;  1LCD A;  2VEO A;  4IVZ A;  2KEK A;  1E3O C;  2PUF A;  4GQM A;  1ZS4 A;  2LYQ A;  3UFD A;  1UXC A;  2MQK A;  2PXU A;  2LYP A;  3G0T A;  2LYS A;  2AW6 A;  3F51 A;  2IVB A;  4MCX A;  2IU7 A;  1U2Z A;  1X2L A;  1POU A;  1GT0 C;  2R63 A;  2MXD A;  2JCG A;  2L8N A;  4X4B A;  3ZPX A;  2AXV A;  1R63 A;  3TEL A;  2AUW A;  4X4D A;  4X4F A;  1QB2 A;  1PRA A;  1XWR A;  2J7W A;  2HCS A;  4YBA A;  3NZL A;  4Z59 A;  2PUC A;  4I6R A;  1QQA A;  2FJR A;  3F6W A;  1PRV A;  1ZZC A;  1B0N A;  2LYJ A;  1JH9 A;  1CQT A; 
#chains in the Genus database with same CATH homology
 4HRA A;  5DT2 A;  3TEL A;  3NXH A;  5DTR A;  3SR4 A;  2YBD A;  3A9X A;  3QFI A;  3VWS A;  3TEP A;  2XXQ A;  4Q2J A;  2L1P A;  4WVL A;  5DRY A;  3TFL A;  4ER6 A;  4DE9 A;  2LLW A;  3G0T A;  5DTQ A;  4DE8 A;  3OKZ A;  2ODR D;  3QOX A;  4ER5 A;  2J7U A;  3PE5 A;  3GUU A;  2J7W A;  2HCS A;  3ME5 A;  3MEJ A;  3NZL A;  2HFZ A;  1NW3 A;  4EQZ A;  2LNM A;  3NRO A;  3A9Z A;  5JUW A;  4EKI A;  2XXP A;  3GZC A;  3UWP A;  4ER0 A;  5DTM A;  1U2Z A;  3M9L A;  4EZI A;  2VEO A;  2HCN A;  3GZD A;  3SX0 A;  4EK9 A;  3OWQ A;  3QOW A;  2MXD A;  5DRT A;  4EKG A;  3GZD C;  5DSX A;  2LLV A;  3A9Y A;  4OBM A;  4ER3 A;  3ZPX A;  4ER7 A;  3R09 A;  2M4H A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...