2HCNA

Crystal structure of rna dependent rna polymerase domain from west nile virus
Total Genus 174
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
174
sequence length
571
structure length
486
Chain Sequence
LVNGVVRLLSKPWDTITTKAPEPPEGVKYVLNETTNWLWAFLAREKRPRMCSREEFIRKVNSNAAQWRSAREAVEDPKFWEMVDEEREAHLRGECHTCRAIWFMWLGARFLEFEALGFLNEDHWLGRKNSGGGVEGLGLQKLGYILREVGTRPGGRIYADDTAGWDTRITRADLENEAKVLELLDGEHRRLARAIIELTYRSGQVVTYALNTFTNLAVQLVRMMEGEGVIGPDDVEKLTKGKGPKVRTWLSENGEERLSRMAVSGDDCVVKPLDDRFATSLHFLNAMSKVRKDIQEWKPSTGWYDWQQVPFCSNHFTELIMKDGRTLVTPCRGQDELVGRARISPNVRDTACLAKSYAQMWLLLYFHRRDLRLMANAICSAVPVNWVPTGRTTWSIHAGGEWMTTEDMLEVWNRVWIEENEWMEDKTPVEKWSDVPYSGKREDIWCGSLIGTRARATWAENIQVAINQVRSIIGDEKYVDYMSSLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
pubmed doi rcsb
molecule tags Transferase
source organism Kunjin virus
molecule keywords RNA-directed RNA polymerase (NS5)
total genus 174
structure length 486
sequence length 571
ec nomenclature ec 2.1.1.56: mRNA (guanine-N(7)-)-methyltransferase.
pdb deposition date 2006-06-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.260.90 Mainly Alpha Orthogonal Bundle 434 Repressor (Amino-terminal Domain) 434 Repressor (Amino-terminal Domain) 2hcnA03
2HCSA 2HFZA 2J7UA 3VWSA 2HCNA 2J7WA
chains in the Genus database with same CATH superfamily
2XCJA 2LYQA 3SR4A 3TELA 1UXDA 2AXZA 2IU7A 2BJCA 1PRVA 5DTMA 3H5TA 1SQ8A 2LYPA 3U3WA 1RZRD 1L1MA 2BNNA 4J1WA 1RZRA 1QQAA 4X4DA 4F8DA 3L1PA 1R69A 3GUUA 1PNRA 2PXFA 1R63A 5DTRA 4I6TA 2BNMA 2J7WA 3VK0A 2ODRD 1BDHA 4PU4C 2GZUA 2O38A 4ER5A 2EWTA 1Y9QA 5GAGi 2ICTA 3QYXA 4ER6A 3OKZA 1AU7A 3GBFA 1DULA 1JH9A 4PU7A 3SCHA 3GN5A 1WIZA 2PUBA 1BDIA 1QZXA 1ADRA 4IVZA 3GZCA 2KEKA 1ZZ7A 3PE5A 4ER7A 4FBIA 1ZAYA 3QWGA 3O9XA 2V3CC 2LYSA 1WETA 2XSDC 2LYJA 3QOWA 1ZZ6A 2XIUA 1UTXA 3OP9A 3IVPA 1HF0A 1ZZBA 3FYAA 3KJXA 1NEQA 3ZHIA 3NXHA 1ZZCA 3LQXA 2JQEA 3DM5A 3QF3A 2B5AA 1LCDA 4WVLA 1QQBA 4Z58A 4PU8A 3S8QA 4EKIA 3QOXA 1IC8A 2XJ3A 5K98B 1RPEL 3LFPA 2M4HA 2OFYA 4X4EA 1ZZ9A 1WH6A 3QQ6A 2XXPA 2L1PA 3B7HA 4YBAA 2LYRA 2HSGA 1S7EA 3GN5B 1RIOA 3CECA 4X4BA 3ZKCA 2PXBA 2FJRA 2PXKA 2XXAA 1QP7A 2FFHA 3F51A 4IA8A 1JFTA 3A9XA 3JXBC 3TEPA 4FN3A 5DSXA 1XWRA 2EBYA 5GAHi 4I6UA 3R1FA 4J1XA 2CSFA 3KZ3A 2AWIA 4ER0A 3BS3A 4O8BA 2L49A 1X57A 1E3OC 2VEOA 1PRUA 2PXUA 4I8TA 2HFZA 1QPZA 1QP4A 1PRAA 3SCFA 1ZPQA 4Z5DA 3SX0A 3LISA 3TFLA 1ZS4A 3NZLA 2PXLA 3A9YA 2L8NA 2YBDA 4DE8A 2KPJA 4IWRA 2KEJA 3MLFA 5DTQA 2KEIA 1NERA 2AW6A 4Z59A 3PXPA 5DRTA 3GZDC 4Y42A 2EF8A 1JFSA 2AUWA 1RZSA 2LLWA 1HQ1A 2PUDA 2WUSR 1Y7YA 2IV1A 2AXUA 1MFQC 2MEZA 4JCXA 3UFDA 2JCGA 2HCSA 3QFIA 4EQZA 4X4GA 3M9LA 3EUSA 2GRMA 2PIJA 1PERL 3UWPA 4EKGA 2MQKA 2PXDA 1LQCA 1YSEA 2CROA 1UXCA 4JQDA 1OSLA 4GHJA 3FMYA 2J7UA 3JXDL 4DE9A 2R63A 1LCCA 3ZPXA 4OB4A 3GZDA 3F52A 3KXAA 4OBMA 3G0TA 2IVQA 2PXPA 2PUFA 4Z5HA 4MCTA 1U2ZA 5JUWA 1LLIA 3NDBB 2LLVA 4X4FA 1X2LA 2D5VA 4EK9A 3VWSA 2LNMA 3R09A 2BNOA 1WH8A 4GQMA 1GT0C 3OQOA 1LMB3 2HINA 2PUCA 2KZ8A 5DT2A 2OR1L 1VPWA 1B0NA 3A9ZA 4YG4A 4X4HA 3BDNA 3JXCL 3CLCA 2LCVA 3KL4A 4X4IA 1DW9A 2PXEA 2IVGA 4Q2JA 3HZIB 4Z5CA 3OQNA 2PUAA 2PXVA 4X4CA 1NW3A 2O49A 2A6CA 2PXTA 2O4AA 2LYKA 2XI8A 3CROL 1OCTC 2PPXA 2PXQA 2JVLA 2LYLA 3OQMA 4YARA 2R1JL 2MXDA 4MCXA 4JCYA 3ME5A 2H8RA 1DWKA 3BD1A 2PUGA 1ZUGA 3SCGA 1POUA 2HCNA 3RZZA 1EFAA 4YG1A 3MEJA 3OMTA 2XXQA 2PUEA 2AXVA 3NROA 2ICPA 4EZIA 2WIUB 3G5GA 3G7DA 3DNVB 5DRYA 2IUOA 1O4XA 4HRAA 4ER3A 4NDWA 4YG7B 5A7LA 2PE5A 1ZVVA 1CQTA 3F6WA 2IVBA 1JWLA 4I6RA 3ZHMA 3OWQA 4PU3C 1QP0A 3FYMA 3TRBA 3D1NI 1CJGA 2GRLA 1ZZ8A 1QB2A
chains in the Genus database with same CATH topology
3GZDA 4ER3A 3GZCA 3TFLA 3TEPA 4OBMA 3G0TA 5DSXA 3SR4A 4ER5A 2HCNA 3NZLA 1NW3A 3GUUA 3A9YA 3PE5A 5DT2A 3SX0A 3TELA 2YBDA 3A9ZA 4EKIA 3MEJA 1U2ZA 3QOXA 4DE8A 5JUWA 2XXQA 4ER6A 4ER7A 4ER0A 3OWQA 3NROA 3OKZA 5DTQA 2M4HA 2LLVA 2HCSA 5DTRA 3NXHA 4EZIA 2J7UA 3QFIA 4Q2JA 4EK9A 5DRTA 3GZDC 3VWSA 4EQZA 2XXPA 3M9LA 2J7WA 2VEOA 2LNMA 5DTMA 3A9XA 2MXDA 2L1PA 3R09A 3UWPA 2HFZA 2ODRD 3ME5A 4EKGA 4DE9A 4WVLA 5DRYA 3ZPXA 3QOWA 2LLWA 4HRAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HCS A;  2HFZ A;  2J7U A;  3VWS A;  2HCN A;  2J7W A; 
#chains in the Genus database with same CATH topology
 2XCJ A;  2LYQ A;  3SR4 A;  3TEL A;  1UXD A;  2AXZ A;  2IU7 A;  2BJC A;  1PRV A;  5DTM A;  3H5T A;  1SQ8 A;  2LYP A;  3U3W A;  1RZR D;  1L1M A;  2BNN A;  4J1W A;  1RZR A;  1QQA A;  4X4D A;  4F8D A;  3L1P A;  1R69 A;  3GUU A;  1PNR A;  2PXF A;  1R63 A;  5DTR A;  4I6T A;  2BNM A;  2J7W A;  3VK0 A;  2ODR D;  1BDH A;  4PU4 C;  2GZU A;  2O38 A;  4ER5 A;  2EWT A;  1Y9Q A;  5GAG i;  2ICT A;  3QYX A;  4ER6 A;  3OKZ A;  1AU7 A;  3GBF A;  1DUL A;  1JH9 A;  4PU7 A;  3SCH A;  3GN5 A;  1WIZ A;  2PUB A;  1BDI A;  1QZX A;  1ADR A;  4IVZ A;  3GZC A;  2KEK A;  1ZZ7 A;  3PE5 A;  4ER7 A;  4FBI A;  1ZAY A;  3QWG A;  3O9X A;  2V3C C;  2LYS A;  1WET A;  2XSD C;  2LYJ A;  3QOW A;  1ZZ6 A;  2XIU A;  1UTX A;  3OP9 A;  3IVP A;  1HF0 A;  1ZZB A;  3FYA A;  3KJX A;  1NEQ A;  3ZHI A;  3NXH A;  1ZZC A;  3LQX A;  2JQE A;  3DM5 A;  3QF3 A;  2B5A A;  1LCD A;  4WVL A;  1QQB A;  4Z58 A;  4PU8 A;  3S8Q A;  4EKI A;  3QOX A;  1IC8 A;  2XJ3 A;  5K98 B;  1RPE L;  3LFP A;  2M4H A;  2OFY A;  4X4E A;  1ZZ9 A;  1WH6 A;  3QQ6 A;  2XXP A;  2L1P A;  3B7H A;  4YBA A;  2LYR A;  2HSG A;  1S7E A;  3GN5 B;  1RIO A;  3CEC A;  4X4B A;  3ZKC A;  2PXB A;  2FJR A;  2PXK A;  2XXA A;  1QP7 A;  2FFH A;  3F51 A;  4IA8 A;  1JFT A;  3A9X A;  3JXB C;  3TEP A;  4FN3 A;  5DSX A;  1XWR A;  2EBY A;  5GAH i;  4I6U A;  3R1F A;  4J1X A;  2CSF A;  3KZ3 A;  2AWI A;  4ER0 A;  3BS3 A;  4O8B A;  2L49 A;  1X57 A;  1E3O C;  2VEO A;  1PRU A;  2PXU A;  4I8T A;  2HFZ A;  1QPZ A;  1QP4 A;  1PRA A;  3SCF A;  1ZPQ A;  4Z5D A;  3SX0 A;  3LIS A;  3TFL A;  1ZS4 A;  3NZL A;  2PXL A;  3A9Y A;  2L8N A;  2YBD A;  4DE8 A;  2KPJ A;  4IWR A;  2KEJ A;  3MLF A;  5DTQ A;  2KEI A;  1NER A;  2AW6 A;  4Z59 A;  3PXP A;  5DRT A;  3GZD C;  4Y42 A;  2EF8 A;  1JFS A;  2AUW A;  1RZS A;  2LLW A;  1HQ1 A;  2PUD A;  2WUS R;  1Y7Y A;  2IV1 A;  2AXU A;  1MFQ C;  2MEZ A;  4JCX A;  3UFD A;  2JCG A;  2HCS A;  3QFI A;  4EQZ A;  4X4G A;  3M9L A;  3EUS A;  2GRM A;  2PIJ A;  1PER L;  3UWP A;  4EKG A;  2MQK A;  2PXD A;  1LQC A;  1YSE A;  2CRO A;  1UXC A;  4JQD A;  1OSL A;  4GHJ A;  3FMY A;  2J7U A;  3JXD L;  4DE9 A;  2R63 A;  1LCC A;  3ZPX A;  4OB4 A;  3GZD A;  3F52 A;  3KXA A;  4OBM A;  3G0T A;  2IVQ A;  2PXP A;  2PUF A;  4Z5H A;  4MCT A;  1U2Z A;  5JUW A;  1LLI A;  3NDB B;  2LLV A;  4X4F A;  1X2L A;  2D5V A;  4EK9 A;  3VWS A;  2LNM A;  3R09 A;  2BNO A;  1WH8 A;  4GQM A;  1GT0 C;  3OQO A;  1LMB 3;  2HIN A;  2PUC A;  2KZ8 A;  5DT2 A;  2OR1 L;  1VPW A;  1B0N A;  3A9Z A;  4YG4 A;  4X4H A;  3BDN A;  3JXC L;  3CLC A;  2LCV A;  3KL4 A;  4X4I A;  1DW9 A;  2PXE A;  2IVG A;  4Q2J A;  3HZI B;  4Z5C A;  3OQN A;  2PUA A;  2PXV A;  4X4C A;  1NW3 A;  2O49 A;  2A6C A;  2PXT A;  2O4A A;  2LYK A;  2XI8 A;  3CRO L;  1OCT C;  2PPX A;  2PXQ A;  2JVL A;  2LYL A;  3OQM A;  4YAR A;  2R1J L;  2MXD A;  4MCX A;  4JCY A;  3ME5 A;  2H8R A;  1DWK A;  3BD1 A;  2PUG A;  1ZUG A;  3SCG A;  1POU A;  2HCN A;  3RZZ A;  1EFA A;  4YG1 A;  3MEJ A;  3OMT A;  2XXQ A;  2PUE A;  2AXV A;  3NRO A;  2ICP A;  4EZI A;  2WIU B;  3G5G A;  3G7D A;  3DNV B;  5DRY A;  2IUO A;  1O4X A;  4HRA A;  4ER3 A;  4NDW A;  4YG7 B;  5A7L A;  2PE5 A;  1ZVV A;  1CQT A;  3F6W A;  2IVB A;  1JWL A;  4I6R A;  3ZHM A;  3OWQ A;  4PU3 C;  1QP0 A;  3FYM A;  3TRB A;  3D1N I;  1CJG A;  2GRL A;  1ZZ8 A;  1QB2 A; 
#chains in the Genus database with same CATH homology
 3GZD A;  4ER3 A;  3GZC A;  3TFL A;  3TEP A;  4OBM A;  3G0T A;  5DSX A;  3SR4 A;  4ER5 A;  2HCN A;  3NZL A;  1NW3 A;  3GUU A;  3A9Y A;  3PE5 A;  5DT2 A;  3SX0 A;  3TEL A;  2YBD A;  3A9Z A;  4EKI A;  3MEJ A;  1U2Z A;  3QOX A;  4DE8 A;  5JUW A;  2XXQ A;  4ER6 A;  4ER7 A;  4ER0 A;  3OWQ A;  3NRO A;  3OKZ A;  5DTQ A;  2M4H A;  2LLV A;  2HCS A;  5DTR A;  3NXH A;  4EZI A;  2J7U A;  3QFI A;  4Q2J A;  4EK9 A;  5DRT A;  3GZD C;  3VWS A;  4EQZ A;  2XXP A;  3M9L A;  2J7W A;  2VEO A;  2LNM A;  5DTM A;  3A9X A;  2MXD A;  2L1P A;  3R09 A;  3UWP A;  2HFZ A;  2ODR D;  3ME5 A;  4EKG A;  4DE9 A;  4WVL A;  5DRY A;  3ZPX A;  3QOW A;  2LLW A;  4HRA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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