2HCSA

Crystal structure of rna dependant rna polymerase domain of west nile virus
Total Genus 175
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
570
structure length
487
Chain Sequence
LVNGVVRLLSKPWDTIDTKAPEPPEGVKYVLNETTNWLWAFLAREKRPRMCSREEFIRKVNSNAAQWRSAREAVEDPKFWEMVDEEREAHLRGECHTCSRAIWFMWLGARFLEFEALGFLNEDHWLGRKNSGGGVEGLGLQKLGYILREVGTRPGGRIYADDTAGWDTRITRADLENEAKVLELLDGEHRRLARAIIELTYRGSGQVVTYALNTFTNLAVQLVRMMEGEGVIGPDDVEKLTKGKGPKVRTWLSENGEERLSRMAVSGDDCVVKPLDDRFATSLHFLNAMSKVRKDIQEWKPSTGWYDWQQVPFCSNHFTELIMKDGRTLVTPCRGQDELVGRARISPNVRDTACLAKSYAQMWLLLYFHRRDLRLMANAICSAVPVNWVPTGRTTWSIHAGGEWMTTEDMLEVWNRVWIEENEWMEDKTPVEKWSDVPYSGKREDIWCGSLIGTRARATWAENIQVAINQVRSIIGDEKYVDYMSSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
pubmed doi rcsb
molecule tags Transferase
source organism Kunjin virus
molecule keywords RNA-directed RNA polymerase (NS5)
total genus 175
structure length 487
sequence length 570
ec nomenclature ec 2.1.1.56: mRNA (guanine-N(7)-)-methyltransferase.
pdb deposition date 2006-06-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.260.90 Mainly Alpha Orthogonal Bundle 434 Repressor (Amino-terminal Domain) 434 Repressor (Amino-terminal Domain) 2hcsA03
3VWSA 2HFZA 2HCNA 2HCSA 2J7UA 2J7WA
chains in the Genus database with same CATH superfamily
2AWIA 3D1NI 1UXCA 3IVPA 3F51A 1CJGA 2PXBA 3OP9A 3TRBA 3ZKCA 1X2LA 2IUOA 2YBDA 3KJXA 1BDIA 3PE5A 2IV1A 4IVZA 4Q2JA 4ER7A 4MCTA 4X4GA 3NXHA 2CROA 2HSGA 3OKZA 1BDHA 3VK0A 4EKIA 3NDBB 4YG1A 2WUSR 3QYXA 1QZXA 1JFTA 4X4FA 2JQEA 2BJCA 4I6RA 4WVLA 4Z5CA 2PUBA 4X4EA 2PPXA 4JCYA 4X4IA 3CROL 2PIJA 2LYRA 1PRAA 5DTRA 4NDWA 2PUAA 1DULA 2PXVA 4Z5DA 4ER3A 4ER6A 3A9ZA 2XCJA 2PUEA 3UFDA 4YBAA 2O4AA 1GT0C 3ZPXA 1B0NA 3OQMA 1RPEL 2LNMA 1ZZ9A 1RZRD 2PUDA 2XXAA 2L8NA 4OB4A 1ZZ8A 3BS3A 2EBYA 3QWGA 1ZVVA 2LYKA 3L1PA 2ICTA 4IWRA 4I6TA 3TFLA 2ICPA 3G0TA 2XJ3A 2EF8A 3TEPA 2LLVA 4EQZA 2PXUA 2HCNA 4DE9A 1AU7A 3GZDC 4FBIA 1ZUGA 1O4XA 1LCCA 2PXQA 3ZHIA 3MLFA 5K98B 2CSFA 5GAGi 1DWKA 1JWLA 2IVGA 3SCFA 2BNOA 4YG7B 1OCTC 2GRMA 1UXDA 2LYPA 2R63A 2AUWA 2GZUA 2O49A 4EZIA 2PXPA 4MCXA 4X4CA 2XXQA 3NROA 2PXFA 2MXDA 1ADRA 1OSLA 1UTXA 2BNMA 5DSXA 2A6CA 3S8QA 3FYAA 1XWRA 2D5VA 4O8BA 3SCHA 2KEIA 3JXBC 3U3WA 3MEJA 4GHJA 3GZDA 2XXPA 2IVBA 1LCDA 3LQXA 2XI8A 1NEQA 2KZ8A 1MFQC 1RZRA 1QP7A 3GBFA 3DNVB 3R1FA 3OQNA 1R63A 1POUA 1S7EA 1WH8A 2LYQA 3RZZA 4EKGA 1E3OC 3O9XA 3TELA 2JCGA 5JUWA 3FMYA 3JXCL 4OBMA 2GRLA 2HINA 2FJRA 2PUFA 1YSEA 2AW6A 3JXDL 2LYLA 3R09A 4X4BA 3G5GA 4ER0A 4PU7A 4X4DA 4PU4C 1ZZBA 4J1WA 2H8RA 3QQ6A 2EWTA 1QQBA 3F6WA 3OWQA 1WETA 2PUCA 2XIUA 1Y7YA 4Z5HA 1PRUA 5A7LA 3CLCA 1HF0A 3CECA 2J7UA 2VEOA 2R1JL 1RZSA 1VPWA 1PRVA 3OMTA 2JVLA 3G7DA 2IVQA 1NW3A 2PUGA 3QFIA 1CQTA 2PE5A 3GUUA 1PERL 1X57A 4PU3C 2LLWA 3KZ3A 3NZLA 3ZHMA 3SCGA 1ZAYA 3DM5A 2LCVA 2IU7A 3GZCA 2KEKA 1WH6A 2WIUB 4Z59A 4JQDA 3BD1A 4FN3A 3GN5B 2ODRD 2MEZA 2J7WA 3PXPA 2PXEA 4YARA 1NERA 4Y42A 1WIZA 1DW9A 2PXLA 1ZPQA 3SX0A 2V3CC 1QB2A 4PU8A 2XSDC 1SQ8A 3UWPA 5DTQA 1IC8A 5DRYA 3B7HA 2L1PA 2L49A 4X4HA 4IA8A 2PXTA 1Y9QA 1U2ZA 1ZZ7A 2FFHA 4J1XA 2AXVA 3QOXA 1QP4A 1ZZCA 1PNRA 5DT2A 2OFYA 1LQCA 4Z58A 1JFSA 1JH9A 4EK9A 3LFPA 2KPJA 4ER5A 3SR4A 2PXKA 1HQ1A 1LMB3 4HRAA 2MQKA 3FYMA 4DE8A 3M9LA 3GN5A 3VWSA 2AXZA 2HFZA 4I6UA 1QP0A 2PXDA 3A9XA 3KXAA 2OR1L 1QPZA 3QF3A 5DTMA 3EUSA 5GAHi 3OQOA 1R69A 4GQMA 4YG4A 2BNNA 5DRTA 3ME5A 2LYSA 4JCXA 1LLIA 4I8TA 2AXUA 3A9YA 1L1MA 1RIOA 2M4HA 1QQAA 4F8DA 3H5TA 3HZIB 2LYJA 2KEJA 1ZZ6A 3F52A 2O38A 1EFAA 3KL4A 1ZS4A 2B5AA 3QOWA 3BDNA 3LISA 2HCSA
chains in the Genus database with same CATH topology
2XXPA 4ER5A 3A9XA 5DRYA 2XXQA 3NXHA 3SR4A 3NROA 2L1PA 3OKZA 2LNMA 2MXDA 3OWQA 4EKIA 3G0TA 5DTMA 1NW3A 3TEPA 2LLVA 4HRAA 4EQZA 5DTRA 1U2ZA 2ODRD 3QFIA 3R09A 3QOXA 3GUUA 2J7WA 2YBDA 2HCNA 4DE9A 4DE8A 4ER3A 4ER6A 5DRTA 2LLWA 3A9ZA 4EKGA 3GZDC 5DT2A 3ME5A 3NZLA 5DSXA 3M9LA 3TELA 2J7UA 4ER0A 3SX0A 5JUWA 2VEOA 3PE5A 3VWSA 4OBMA 5DTQA 3UWPA 4EK9A 4WVLA 4EZIA 2HFZA 3A9YA 3QOWA 3ZPXA 4Q2JA 2HCSA 4ER7A 3MEJA 3TFLA 3GZCA 3GZDA 2M4HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VWS A;  2HFZ A;  2HCN A;  2HCS A;  2J7U A;  2J7W A; 
#chains in the Genus database with same CATH topology
 2AWI A;  3D1N I;  1UXC A;  3IVP A;  3F51 A;  1CJG A;  2PXB A;  3OP9 A;  3TRB A;  3ZKC A;  1X2L A;  2IUO A;  2YBD A;  3KJX A;  1BDI A;  3PE5 A;  2IV1 A;  4IVZ A;  4Q2J A;  4ER7 A;  4MCT A;  4X4G A;  3NXH A;  2CRO A;  2HSG A;  3OKZ A;  1BDH A;  3VK0 A;  4EKI A;  3NDB B;  4YG1 A;  2WUS R;  3QYX A;  1QZX A;  1JFT A;  4X4F A;  2JQE A;  2BJC A;  4I6R A;  4WVL A;  4Z5C A;  2PUB A;  4X4E A;  2PPX A;  4JCY A;  4X4I A;  3CRO L;  2PIJ A;  2LYR A;  1PRA A;  5DTR A;  4NDW A;  2PUA A;  1DUL A;  2PXV A;  4Z5D A;  4ER3 A;  4ER6 A;  3A9Z A;  2XCJ A;  2PUE A;  3UFD A;  4YBA A;  2O4A A;  1GT0 C;  3ZPX A;  1B0N A;  3OQM A;  1RPE L;  2LNM A;  1ZZ9 A;  1RZR D;  2PUD A;  2XXA A;  2L8N A;  4OB4 A;  1ZZ8 A;  3BS3 A;  2EBY A;  3QWG A;  1ZVV A;  2LYK A;  3L1P A;  2ICT A;  4IWR A;  4I6T A;  3TFL A;  2ICP A;  3G0T A;  2XJ3 A;  2EF8 A;  3TEP A;  2LLV A;  4EQZ A;  2PXU A;  2HCN A;  4DE9 A;  1AU7 A;  3GZD C;  4FBI A;  1ZUG A;  1O4X A;  1LCC A;  2PXQ A;  3ZHI A;  3MLF A;  5K98 B;  2CSF A;  5GAG i;  1DWK A;  1JWL A;  2IVG A;  3SCF A;  2BNO A;  4YG7 B;  1OCT C;  2GRM A;  1UXD A;  2LYP A;  2R63 A;  2AUW A;  2GZU A;  2O49 A;  4EZI A;  2PXP A;  4MCX A;  4X4C A;  2XXQ A;  3NRO A;  2PXF A;  2MXD A;  1ADR A;  1OSL A;  1UTX A;  2BNM A;  5DSX A;  2A6C A;  3S8Q A;  3FYA A;  1XWR A;  2D5V A;  4O8B A;  3SCH A;  2KEI A;  3JXB C;  3U3W A;  3MEJ A;  4GHJ A;  3GZD A;  2XXP A;  2IVB A;  1LCD A;  3LQX A;  2XI8 A;  1NEQ A;  2KZ8 A;  1MFQ C;  1RZR A;  1QP7 A;  3GBF A;  3DNV B;  3R1F A;  3OQN A;  1R63 A;  1POU A;  1S7E A;  1WH8 A;  2LYQ A;  3RZZ A;  4EKG A;  1E3O C;  3O9X A;  3TEL A;  2JCG A;  5JUW A;  3FMY A;  3JXC L;  4OBM A;  2GRL A;  2HIN A;  2FJR A;  2PUF A;  1YSE A;  2AW6 A;  3JXD L;  2LYL A;  3R09 A;  4X4B A;  3G5G A;  4ER0 A;  4PU7 A;  4X4D A;  4PU4 C;  1ZZB A;  4J1W A;  2H8R A;  3QQ6 A;  2EWT A;  1QQB A;  3F6W A;  3OWQ A;  1WET A;  2PUC A;  2XIU A;  1Y7Y A;  4Z5H A;  1PRU A;  5A7L A;  3CLC A;  1HF0 A;  3CEC A;  2J7U A;  2VEO A;  2R1J L;  1RZS A;  1VPW A;  1PRV A;  3OMT A;  2JVL A;  3G7D A;  2IVQ A;  1NW3 A;  2PUG A;  3QFI A;  1CQT A;  2PE5 A;  3GUU A;  1PER L;  1X57 A;  4PU3 C;  2LLW A;  3KZ3 A;  3NZL A;  3ZHM A;  3SCG A;  1ZAY A;  3DM5 A;  2LCV A;  2IU7 A;  3GZC A;  2KEK A;  1WH6 A;  2WIU B;  4Z59 A;  4JQD A;  3BD1 A;  4FN3 A;  3GN5 B;  2ODR D;  2MEZ A;  2J7W A;  3PXP A;  2PXE A;  4YAR A;  1NER A;  4Y42 A;  1WIZ A;  1DW9 A;  2PXL A;  1ZPQ A;  3SX0 A;  2V3C C;  1QB2 A;  4PU8 A;  2XSD C;  1SQ8 A;  3UWP A;  5DTQ A;  1IC8 A;  5DRY A;  3B7H A;  2L1P A;  2L49 A;  4X4H A;  4IA8 A;  2PXT A;  1Y9Q A;  1U2Z A;  1ZZ7 A;  2FFH A;  4J1X A;  2AXV A;  3QOX A;  1QP4 A;  1ZZC A;  1PNR A;  5DT2 A;  2OFY A;  1LQC A;  4Z58 A;  1JFS A;  1JH9 A;  4EK9 A;  3LFP A;  2KPJ A;  4ER5 A;  3SR4 A;  2PXK A;  1HQ1 A;  1LMB 3;  4HRA A;  2MQK A;  3FYM A;  4DE8 A;  3M9L A;  3GN5 A;  3VWS A;  2AXZ A;  2HFZ A;  4I6U A;  1QP0 A;  2PXD A;  3A9X A;  3KXA A;  2OR1 L;  1QPZ A;  3QF3 A;  5DTM A;  3EUS A;  5GAH i;  3OQO A;  1R69 A;  4GQM A;  4YG4 A;  2BNN A;  5DRT A;  3ME5 A;  2LYS A;  4JCX A;  1LLI A;  4I8T A;  2AXU A;  3A9Y A;  1L1M A;  1RIO A;  2M4H A;  1QQA A;  4F8D A;  3H5T A;  3HZI B;  2LYJ A;  2KEJ A;  1ZZ6 A;  3F52 A;  2O38 A;  1EFA A;  3KL4 A;  1ZS4 A;  2B5A A;  3QOW A;  3BDN A;  3LIS A;  2HCS A; 
#chains in the Genus database with same CATH homology
 2XXP A;  4ER5 A;  3A9X A;  5DRY A;  2XXQ A;  3NXH A;  3SR4 A;  3NRO A;  2L1P A;  3OKZ A;  2LNM A;  2MXD A;  3OWQ A;  4EKI A;  3G0T A;  5DTM A;  1NW3 A;  3TEP A;  2LLV A;  4HRA A;  4EQZ A;  5DTR A;  1U2Z A;  2ODR D;  3QFI A;  3R09 A;  3QOX A;  3GUU A;  2J7W A;  2YBD A;  2HCN A;  4DE9 A;  4DE8 A;  4ER3 A;  4ER6 A;  5DRT A;  2LLW A;  3A9Z A;  4EKG A;  3GZD C;  5DT2 A;  3ME5 A;  3NZL A;  5DSX A;  3M9L A;  3TEL A;  2J7U A;  4ER0 A;  3SX0 A;  5JUW A;  2VEO A;  3PE5 A;  3VWS A;  4OBM A;  5DTQ A;  3UWP A;  4EK9 A;  4WVL A;  4EZI A;  2HFZ A;  3A9Y A;  3QOW A;  3ZPX A;  4Q2J A;  2HCS A;  4ER7 A;  3MEJ A;  3TFL A;  3GZC A;  3GZD A;  2M4H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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